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Items: 1 to 50 of 114

1.

Scalable Fabrication of Organic Single-Crystalline Wafers for Reproducible TFT Arrays.

Kumagai S, Yamamura A, Makita T, Tsurumi J, Lim YY, Wakimoto T, Isahaya N, Nozawa H, Sato K, Mitani M, Okamoto T, Watanabe S, Takeya J.

Sci Rep. 2019 Nov 4;9(1):15897. doi: 10.1038/s41598-019-50294-x.

2.

Crystal Structures of Flavone C-Glycosides from Oolong Tea Leaves: Chafuroside A Dihydrate and Chafuroside B Monohydrate.

Iwao Y, Ishida H, Kimura SI, Wakimoto T, Kondo H, Itai S, Noguchi S.

Chem Pharm Bull (Tokyo). 2019;67(9):935-939. doi: 10.1248/cpb.c19-00166.

3.

The Revised Structure of the Cyclic Octapeptide Surugamide A.

Matsuda K, Kuranaga T, Sano A, Ninomiya A, Takada K, Wakimoto T.

Chem Pharm Bull (Tokyo). 2019;67(5):476-480. doi: 10.1248/cpb.c19-00002.

4.

Scrobiculosides A and B from the deep-sea sponge Pachastrella scrobiculosa.

Jomori T, Shiroyama S, Ise Y, Kohtsuka H, Matsuda K, Kuranaga T, Wakimoto T.

J Nat Med. 2019 Sep;73(4):814-819. doi: 10.1007/s11418-019-01315-6. Epub 2019 May 3.

PMID:
31054009
5.

SurE is a trans-acting thioesterase cyclizing two distinct non-ribosomal peptides.

Matsuda K, Kobayashi M, Kuranaga T, Takada K, Ikeda H, Matsunaga S, Wakimoto T.

Org Biomol Chem. 2019 Jan 31;17(5):1058-1061. doi: 10.1039/c8ob02867b.

PMID:
30637418
6.

Impact of maternal methylenetetrahydrofolate reductase C677T polymorphism on intervillous and decidual pathology with pregnancy loss.

Mehandjiev TR, Tenno NM, Nakura Y, Georgiev TP, Minekawa R, Wakimoto T, Mimura K, Nakayama M, Kawakami K, Kanagawa T, Tomimatsu T, Fujita T, Onouchi Y, Takeuchi M, Kimura T, Yanagihara I.

J Obstet Gynaecol Res. 2019 Jan;45(1):78-85. doi: 10.1111/jog.13798. Epub 2018 Aug 23.

PMID:
30136429
7.

Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria.

Matsuda K, Tomita T, Shin-Ya K, Wakimoto T, Kuzuyama T, Nishiyama M.

J Am Chem Soc. 2018 Jul 25;140(29):9083-9086. doi: 10.1021/jacs.8b05354. Epub 2018 Jul 17.

PMID:
30001119
8.

Diastereoselective Total Synthesis and Structural Confirmation of Surugamide F.

Kuranaga T, Fukuba A, Ninomiya A, Takada K, Matsunaga S, Wakimoto T.

Chem Pharm Bull (Tokyo). 2018;66(6):637-641. doi: 10.1248/cpb.c18-00072.

9.

Total Synthesis of the Nonribosomal Peptide Surugamide B and Identification of a New Offloading Cyclase Family.

Kuranaga T, Matsuda K, Sano A, Kobayashi M, Ninomiya A, Takada K, Matsunaga S, Wakimoto T.

Angew Chem Int Ed Engl. 2018 Jul 20;57(30):9447-9451. doi: 10.1002/anie.201805541. Epub 2018 Jun 25.

PMID:
29808953
10.

Biosynthetic Insights of Calyculin- and Misakinolide-Type Compounds in "Candidatus Entotheonella sp."

Uria AR, Piel J, Wakimoto T.

Methods Enzymol. 2018;604:287-330. doi: 10.1016/bs.mie.2018.02.017. Epub 2018 May 7.

PMID:
29779656
11.

Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes.

Unno Y, Yamamoto H, Takatsuki S, Sato Y, Kuranaga T, Yazawa K, Ono Y, Wakimoto T.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jul;1863(7):772-782. doi: 10.1016/j.bbalip.2018.04.003. Epub 2018 Apr 12.

PMID:
29654827
12.

Correction to: Protein phosphatases 1 and 2A and their naturally occurring inhibitors: current topics in smooth muscle physiology and chemical biology.

Takai A, Eto M, Hirano K, Takeya K, Wakimoto T, Watanabe M.

J Physiol Sci. 2018 Mar;68(2):201. doi: 10.1007/s12576-017-0577-1.

13.

Corrigendum: Biosynthetic Gene Cluster for Surugamide A Encompasses an Unrelated Decapeptide, Surugamide F.

Ninomiya A, Katsuyama Y, Kuranaga T, Miyazaki M, Nogi Y, Okada S, Wakimoto T, Ohnishi Y, Matsunaga S, Takada K.

Chembiochem. 2017 Sep 5;18(17):1770. doi: 10.1002/cbic.201700401. Epub 2017 Aug 4. No abstract available.

PMID:
28872266
14.

Protein phosphatases 1 and 2A and their naturally occurring inhibitors: current topics in smooth muscle physiology and chemical biology.

Takai A, Eto M, Hirano K, Takeya K, Wakimoto T, Watanabe M.

J Physiol Sci. 2018 Jan;68(1):1-17. doi: 10.1007/s12576-017-0556-6. Epub 2017 Jul 5. Review. Erratum in: J Physiol Sci. 2017 Nov 27;:.

15.

Toward the Dark Matter of Natural Products.

Wakimoto T.

Chem Rec. 2017 Nov;17(11):1124-1134. doi: 10.1002/tcr.201700009. Epub 2017 Apr 18.

PMID:
28418111
16.

Identification of Pyridinium with Three Indole Moieties as an Antimicrobial Agent.

Okada M, Sugita T, Wong CP, Wakimoto T, Abe I.

J Nat Prod. 2017 Apr 28;80(4):1205-1209. doi: 10.1021/acs.jnatprod.6b01152. Epub 2017 Mar 14.

PMID:
28290701
17.

Total Synthesis of Theonellapeptolide Id.

Kuranaga T, Enomoto A, Tan H, Fujita K, Wakimoto T.

Org Lett. 2017 Mar 17;19(6):1366-1369. doi: 10.1021/acs.orglett.7b00249. Epub 2017 Feb 28.

PMID:
28244756
18.

Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.

Zhang L, Hashimoto T, Qin B, Hashimoto J, Kozone I, Kawahara T, Okada M, Awakawa T, Ito T, Asakawa Y, Ueki M, Takahashi S, Osada H, Wakimoto T, Ikeda H, Shin-Ya K, Abe I.

Angew Chem Int Ed Engl. 2017 Feb 6;56(7):1740-1745. doi: 10.1002/anie.201611371. Epub 2017 Jan 11.

PMID:
28133950
19.

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by 'Entotheonella'.

Nakashima Y, Egami Y, Kimura M, Wakimoto T, Abe I.

PLoS One. 2016 Oct 12;11(10):e0164468. doi: 10.1371/journal.pone.0164468. eCollection 2016.

20.

Sulfoureido Lipopeptides from the Marine Sponge Discodermia kiiensis.

Tan KC, Wakimoto T, Abe I.

J Nat Prod. 2016 Sep 23;79(9):2418-22. doi: 10.1021/acs.jnatprod.6b00586. Epub 2016 Aug 23.

PMID:
27551908
21.

Biosynthetic Gene Cluster for Surugamide A Encompasses an Unrelated Decapeptide, Surugamide F.

Ninomiya A, Katsuyama Y, Kuranaga T, Miyazaki M, Nogi Y, Okada S, Wakimoto T, Ohnishi Y, Matsunaga S, Takada K.

Chembiochem. 2016 Sep 15;17(18):1709-12. doi: 10.1002/cbic.201600350. Epub 2016 Jul 22. Erratum in: Chembiochem. 2017 Sep 5;18(17 ):1770.

PMID:
27443244
22.

Structural Diversification of Lyngbyatoxin A by Host-Dependent Heterologous Expression of the tleABC Biosynthetic Gene Cluster.

Zhang L, Hoshino S, Awakawa T, Wakimoto T, Abe I.

Chembiochem. 2016 Aug 3;17(15):1407-11. doi: 10.1002/cbic.201600229. Epub 2016 Jun 17.

PMID:
27194569
23.

Does voluntary hypoventilation during exercise impact EMG activity?

Kume D, Akahoshi S, Yamagata T, Wakimoto T, Nagao N.

Springerplus. 2016 Feb 24;5:149. doi: 10.1186/s40064-016-1845-x. eCollection 2016.

24.

Calyculin: Nature's way of making the sponge-derived cytotoxin.

Wakimoto T, Egami Y, Abe I.

Nat Prod Rep. 2016 Jun 2;33(6):751-60. doi: 10.1039/c5np00123d. Review.

PMID:
26923942
25.

Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol.

Asakawa T, Kawabe Y, Yoshida A, Aihara Y, Manabe T, Hirose Y, Sakurada A, Inai M, Hamashima Y, Furuta T, Wakimoto T, Kan T.

J Antibiot (Tokyo). 2016 Apr;69(4):299-312. doi: 10.1038/ja.2016.14. Epub 2016 Feb 24.

PMID:
26905756
26.

Niizalactams A-C, Multicyclic Macrolactams Isolated from Combined Culture of Streptomyces with Mycolic Acid-Containing Bacterium.

Hoshino S, Okada M, Wakimoto T, Zhang H, Hayashi F, Onaka H, Abe I.

J Nat Prod. 2015 Dec 24;78(12):3011-7. doi: 10.1021/acs.jnatprod.5b00804. Epub 2015 Dec 1.

PMID:
26624939
27.

An Unusual Chimeric Diterpene Synthase from Emericella variecolor and Its Functional Conversion into a Sesterterpene Synthase by Domain Swapping.

Qin B, Matsuda Y, Mori T, Okada M, Quan Z, Mitsuhashi T, Wakimoto T, Abe I.

Angew Chem Int Ed Engl. 2016 Jan 26;55(5):1658-61. doi: 10.1002/anie.201509263. Epub 2015 Nov 6.

PMID:
26546087
28.

Surfactant protein-D attenuates the lipopolysaccharide-induced inflammation in human intestinal cells overexpressing toll-like receptor 4.

Saka R, Wakimoto T, Nishiumi F, Sasaki T, Nose S, Fukuzawa M, Oue T, Yanagihara I, Okuyama H.

Pediatr Surg Int. 2016 Jan;32(1):59-63. doi: 10.1007/s00383-015-3812-y. Epub 2015 Oct 28.

PMID:
26510735
29.

Dietziamides, novel tetramic acid dimers from Dietzia timorensis MZ-3 with antioxidative activity.

Hoshino S, Wakimoto T, Zhang H, Hayashi F, Okada M, Abe I.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):3953-5. doi: 10.1016/j.bmcl.2015.07.035. Epub 2015 Jul 18.

PMID:
26220156
30.

Hydroxylated fullerene: a potential antiinflammatory and antioxidant agent for preventing mouse preterm birth.

Wakimoto T, Uchida K, Mimura K, Kanagawa T, Mehandjiev TR, Aoshima H, Kokubo K, Mitsuda N, Yoshioka Y, Tsutsumi Y, Kimura T, Yanagihara I.

Am J Obstet Gynecol. 2015 Nov;213(5):708.e1-9. doi: 10.1016/j.ajog.2015.07.017. Epub 2015 Jul 18.

PMID:
26196453
31.

Structural Basis for β-Carboline Alkaloid Production by the Microbial Homodimeric Enzyme McbB.

Mori T, Hoshino S, Sahashi S, Wakimoto T, Matsui T, Morita H, Abe I.

Chem Biol. 2015 Jul 23;22(7):898-906. doi: 10.1016/j.chembiol.2015.06.006. Epub 2015 Jun 25.

32.

Production of indole antibiotics induced by exogenous gene derived from sponge metagenomes.

Takeshige Y, Egami Y, Wakimoto T, Abe I.

Mol Biosyst. 2015 May;11(5):1290-4. doi: 10.1039/c5mb00131e.

PMID:
25828760
33.

Chojalactones A-C, cytotoxic butanolides isolated from Streptomyces sp. cultivated with mycolic acid containing bacterium.

Hoshino S, Wakimoto T, Onaka H, Abe I.

Org Lett. 2015 Mar 20;17(6):1501-4. doi: 10.1021/acs.orglett.5b00385. Epub 2015 Mar 5.

PMID:
25742189
34.

Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase.

Matsuda Y, Iwabuchi T, Wakimoto T, Awakawa T, Abe I.

J Am Chem Soc. 2015 Mar 11;137(9):3393-401. doi: 10.1021/jacs.5b00570. Epub 2015 Feb 25.

PMID:
25671343
35.

In vitro activity of five quinolones and analysis of the quinolone resistance-determining regions of gyrA, gyrB, parC, and parE in Ureaplasma parvum and Ureaplasma urealyticum clinical isolates from perinatal patients in Japan.

Kawai Y, Nakura Y, Wakimoto T, Nomiyama M, Tokuda T, Takayanagi T, Shiraishi J, Wasada K, Kitajima H, Fujita T, Nakayama M, Mitsuda N, Nakanishi I, Takeuchi M, Yanagihara I.

Antimicrob Agents Chemother. 2015 Apr;59(4):2358-64. doi: 10.1128/AAC.04262-14. Epub 2015 Feb 2.

36.

Phosphocalyculin C as a pyrophosphate protoxin of calyculin C in the marine sponge Discodermia calyx.

Egami Y, Wakimoto T, Abe I.

Bioorg Med Chem Lett. 2014 Nov 15;24(22):5150-3. doi: 10.1016/j.bmcl.2014.10.002. Epub 2014 Oct 13.

PMID:
25442302
37.

Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823.

Hoshino S, Zhang L, Awakawa T, Wakimoto T, Onaka H, Abe I.

J Antibiot (Tokyo). 2015 May;68(5):342-4. doi: 10.1038/ja.2014.147. Epub 2014 Oct 22. No abstract available.

PMID:
25335694
38.

Complete biosynthetic pathway of anditomin: nature's sophisticated synthetic route to a complex fungal meroterpenoid.

Matsuda Y, Wakimoto T, Mori T, Awakawa T, Abe I.

J Am Chem Soc. 2014 Oct 29;136(43):15326-36. doi: 10.1021/ja508127q. Epub 2014 Sep 23.

PMID:
25216349
39.

Three acyltetronic acid derivatives: noncanonical cryptic polyketides from Aspergillus niger identified by genome mining.

Yang XL, Awakawa T, Wakimoto T, Abe I.

Chembiochem. 2014 Jul 21;15(11):1578-83. doi: 10.1002/cbic.201402172. Epub 2014 Jul 8.

PMID:
25044953
40.

A methyltransferase initiates terpene cyclization in teleocidin B biosynthesis.

Awakawa T, Zhang L, Wakimoto T, Hoshino S, Mori T, Ito T, Ishikawa J, Tanner ME, Abe I.

J Am Chem Soc. 2014 Jul 16;136(28):9910-3. doi: 10.1021/ja505224r. Epub 2014 Jul 8.

PMID:
24992358
41.

Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.

Wakimoto T, Egami Y, Nakashima Y, Wakimoto Y, Mori T, Awakawa T, Ito T, Kenmoku H, Asakawa Y, Piel J, Abe I.

Nat Chem Biol. 2014 Aug;10(8):648-55. doi: 10.1038/nchembio.1573. Epub 2014 Jun 29.

PMID:
24974231
42.

Lipodiscamides A-C, new cytotoxic lipopeptides from Discodermia kiiensis.

Tan KC, Wakimoto T, Abe I.

Org Lett. 2014 Jun 20;16(12):3256-9. doi: 10.1021/ol501271v. Epub 2014 Jun 6.

PMID:
24906171
43.

Enantioselective synthesis of SB-203207.

Hirooka Y, Ikeuchi K, Kawamoto Y, Akao Y, Furuta T, Asakawa T, Inai M, Wakimoto T, Fukuyama T, Kan T.

Org Lett. 2014 Mar 21;16(6):1646-9. doi: 10.1021/ol5002973. Epub 2014 Mar 6.

PMID:
24601822
44.

An environmental bacterial taxon with a large and distinct metabolic repertoire.

Wilson MC, Mori T, Rückert C, Uria AR, Helf MJ, Takada K, Gernert C, Steffens UA, Heycke N, Schmitt S, Rinke C, Helfrich EJ, Brachmann AO, Gurgui C, Wakimoto T, Kracht M, Crüsemann M, Hentschel U, Abe I, Matsunaga S, Kalinowski J, Takeyama H, Piel J.

Nature. 2014 Feb 6;506(7486):58-62. doi: 10.1038/nature12959. Epub 2014 Jan 29. Erratum in: Nature. 2014 Mar 13;507(7491):262.

PMID:
24476823
45.

Revised structure of cyclolithistide A, a cyclic depsipeptide from the marine sponge Discodermia japonica.

Tajima H, Wakimoto T, Takada K, Ise Y, Abe I.

J Nat Prod. 2014 Jan 24;77(1):154-8. doi: 10.1021/np400668k. Epub 2013 Dec 13.

PMID:
24328201
46.

Effects of Ureaplasma parvum lipoprotein multiple-banded antigen on pregnancy outcome in mice.

Uchida K, Nakahira K, Mimura K, Shimizu T, De Seta F, Wakimoto T, Kawai Y, Nomiyama M, Kuwano K, Guaschino S, Yanagihara I.

J Reprod Immunol. 2013 Dec;100(2):118-27. doi: 10.1016/j.jri.2013.10.001. Epub 2013 Oct 19.

PMID:
24238827
47.

Pyranonigrin E: a PKS-NRPS hybrid metabolite from Aspergillus niger identified by genome mining.

Awakawa T, Yang XL, Wakimoto T, Abe I.

Chembiochem. 2013 Nov 4;14(16):2095-9. doi: 10.1002/cbic.201300430. Epub 2013 Sep 17.

PMID:
24106156
48.

[3:1] site-differentiated [4Fe-4S] clusters having one carboxylate and three thiolates.

Terada T, Hirabayashi K, Liu D, Nakamura T, Wakimoto T, Matsumoto T, Tatsumi K.

Inorg Chem. 2013 Oct 21;52(20):11997-2004. doi: 10.1021/ic4017596. Epub 2013 Oct 8.

PMID:
24102391
49.

Spiro-ring formation is catalyzed by a multifunctional dioxygenase in austinol biosynthesis.

Matsuda Y, Awakawa T, Wakimoto T, Abe I.

J Am Chem Soc. 2013 Jul 31;135(30):10962-5. doi: 10.1021/ja405518u. Epub 2013 Jul 22.

PMID:
23865690
50.

Cycloforskamide, a cytotoxic macrocyclic peptide from the sea slug Pleurobranchus forskalii.

Tan KC, Wakimoto T, Takada K, Ohtsuki T, Uchiyama N, Goda Y, Abe I.

J Nat Prod. 2013 Jul 26;76(7):1388-91. doi: 10.1021/np400404r. Epub 2013 Jul 12.

PMID:
23848233

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