Sort by
Items per page

Send to

Choose Destination

Search results

Items: 25


Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.

Wu T, Guan J, Handel A, Tscharke DC, Sidney J, Sette A, Wakim LM, Sng XYX, Thomas PG, Croft NP, Purcell AW, La Gruta NL.

Nat Commun. 2019 Jun 28;10(1):2846. doi: 10.1038/s41467-019-10661-8.


Human CD8+ T cell cross-reactivity across influenza A, B and C viruses.

Koutsakos M, Illing PT, Nguyen THO, Mifsud NA, Crawford JC, Rizzetto S, Eltahla AA, Clemens EB, Sant S, Chua BY, Wong CY, Allen EK, Teng D, Dash P, Boyd DF, Grzelak L, Zeng W, Hurt AC, Barr I, Rockman S, Jackson DC, Kotsimbos TC, Cheng AC, Richards M, Westall GP, Loudovaris T, Mannering SI, Elliott M, Tangye SG, Wakim LM, Rossjohn J, Vijaykrishna D, Luciani F, Thomas PG, Gras S, Purcell AW, Kedzierska K.

Nat Immunol. 2019 May;20(5):613-625. doi: 10.1038/s41590-019-0320-6. Epub 2019 Feb 18.


Zymosan by-passes the requirement for pulmonary antigen encounter in lung tissue-resident memory CD8+ T cell development.

Caminschi I, Lahoud MH, Pizzolla A, Wakim LM.

Mucosal Immunol. 2019 Mar;12(2):403-412. doi: 10.1038/s41385-018-0124-2. Epub 2019 Jan 21.


Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection.

Bedford JG, O'Keeffe M, Reading PC, Wakim LM.

PLoS One. 2019 Jan 16;14(1):e0210132. doi: 10.1371/journal.pone.0210132. eCollection 2019.


Memory T Cell Dynamics in the Lung during Influenza Virus Infection.

Pizzolla A, Wakim LM.

J Immunol. 2019 Jan 15;202(2):374-381. doi: 10.4049/jimmunol.1800979. Review.


Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

Sant S, Grzelak L, Wang Z, Pizzolla A, Koutsakos M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Wakim LM, Rossjohn J, Gras S, Richards M, Xu J, Thomas PG, Loh L, Nguyen THO, Kedzierska K.

Front Immunol. 2018 Jun 27;9:1453. doi: 10.3389/fimmu.2018.01453. eCollection 2018.


Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine.

Clemens EB, van de Sandt C, Wong SS, Wakim LM, Valkenburg SA.

Vaccines (Basel). 2018 Mar 26;6(2). pii: E18. doi: 10.3390/vaccines6020018. Review.


Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity.

Koutsakos M, Wheatley AK, Loh L, Clemens EB, Sant S, Nüssing S, Fox A, Chung AW, Laurie KL, Hurt AC, Rockman S, Lappas M, Loudovaris T, Mannering SI, Westall GP, Elliot M, Tangye SG, Wakim LM, Kent SJ, Nguyen THO, Kedzierska K.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaan8405. doi: 10.1126/scitranslmed.aan8405.


Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.

Pizzolla A, Nguyen TH, Sant S, Jaffar J, Loudovaris T, Mannering SI, Thomas PG, Westall GP, Kedzierska K, Wakim LM.

J Clin Invest. 2018 Feb 1;128(2):721-733. doi: 10.1172/JCI96957. Epub 2018 Jan 8.


Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

Pizzolla A, Nguyen THO, Smith JM, Brooks AG, Kedzieska K, Heath WR, Reading PC, Wakim LM.

Sci Immunol. 2017 Jun 2;2(12). pii: eaam6970. doi: 10.1126/sciimmunol.aam6970.


Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells.

Pizzolla A, Wang Z, Groom JR, Kedzierska K, Brooks AG, Reading PC, Wakim LM.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5225-5230. doi: 10.1073/pnas.1620194114. Epub 2017 May 1.


When input does not match output, lung-resident memory T cells decay.

Wakim LM.

Immunol Cell Biol. 2017 Apr;95(4):321-322. doi: 10.1038/icb.2017.14. Epub 2017 Mar 14. No abstract available.


Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8+ T Cell Priming.

Infusini G, Smith JM, Yuan H, Pizzolla A, Ng WC, Londrigan SL, Haque A, Reading PC, Villadangos JA, Wakim LM.

PLoS One. 2015 Nov 23;10(11):e0143539. doi: 10.1371/journal.pone.0143539. eCollection 2015.


Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection.

Londrigan SL, Tate MD, Job ER, Moffat JM, Wakim LM, Gonelli CA, Purcell DF, Brooks AG, Villadangos JA, Reading PC, Mintern JD.

PLoS One. 2015 Nov 13;10(11):e0142925. doi: 10.1371/journal.pone.0142925. eCollection 2015.


Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection.

Wakim LM, Smith J, Caminschi I, Lahoud MH, Villadangos JA.

Mucosal Immunol. 2015 Sep;8(5):1060-71. doi: 10.1038/mi.2014.133. Epub 2015 Jan 14.


Enhanced survival of lung tissue-resident memory CD8⁺ T cells during infection with influenza virus due to selective expression of IFITM3.

Wakim LM, Gupta N, Mintern JD, Villadangos JA.

Nat Immunol. 2013 Mar;14(3):238-45. doi: 10.1038/ni.2525. Epub 2013 Jan 27.


The molecular signature of tissue resident memory CD8 T cells isolated from the brain.

Wakim LM, Woodward-Davis A, Liu R, Hu Y, Villadangos J, Smyth G, Bevan MJ.

J Immunol. 2012 Oct 1;189(7):3462-71. Epub 2012 Aug 24.


Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection.

Wakim LM, Bevan MJ.

Nature. 2011 Mar 31;471(7340):629-32. doi: 10.1038/nature09863.


Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence.

Wakim LM, Woodward-Davis A, Bevan MJ.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):17872-9. doi: 10.1073/pnas.1010201107. Epub 2010 Oct 5.


From the thymus to longevity in the periphery.

Wakim LM, Bevan MJ.

Curr Opin Immunol. 2010 Jun;22(3):274-8. doi: 10.1016/j.coi.2010.03.003. Epub 2010 Apr 6. Review.


Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus.

Gebhardt T, Wakim LM, Eidsmo L, Reading PC, Heath WR, Carbone FR.

Nat Immunol. 2009 May;10(5):524-30. doi: 10.1038/ni.1718. Epub 2009 Mar 22.


Cutting edge: local recall responses by memory T cells newly recruited to peripheral nonlymphoid tissues.

Wakim LM, Gebhardt T, Heath WR, Carbone FR.

J Immunol. 2008 Nov 1;181(9):5837-41.


CD8(+) T-cell attenuation of cutaneous herpes simplex virus infection reduces the average viral copy number of the ensuing latent infection.

Wakim LM, Jones CM, Gebhardt T, Preston CM, Carbone FR.

Immunol Cell Biol. 2008 Nov-Dec;86(8):666-75. doi: 10.1038/icb.2008.47. Epub 2008 Jul 8.


Dendritic cell-induced memory T cell activation in nonlymphoid tissues.

Wakim LM, Waithman J, van Rooijen N, Heath WR, Carbone FR.

Science. 2008 Jan 11;319(5860):198-202. doi: 10.1126/science.1151869.


Epidermal viral immunity induced by CD8alpha+ dendritic cells but not by Langerhans cells.

Allan RS, Smith CM, Belz GT, van Lint AL, Wakim LM, Heath WR, Carbone FR.

Science. 2003 Sep 26;301(5641):1925-8.

Supplemental Content

Loading ...
Support Center