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Items: 1 to 20 of 231

1.

Lipidomics: Current state of the art in a fast moving field.

O'Donnell VB, Ekroos K, Liebisch G, Wakelam M.

Wiley Interdiscip Rev Syst Biol Med. 2019 Oct 23:e1466. doi: 10.1002/wsbm.1466. [Epub ahead of print] Review.

PMID:
31646749
2.

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication.

Zhuang X, Magri A, Hill M, Lai AG, Kumar A, Rambhatla SB, Donald CL, Lopez-Clavijo AF, Rudge S, Pinnick K, Chang WH, Wing PAC, Brown R, Qin X, Simmonds P, Baumert TF, Ray D, Loudon A, Balfe P, Wakelam M, Butterworth S, Kohl A, Jopling CL, Zitzmann N, McKeating JA.

Nat Commun. 2019 Jan 22;10(1):377. doi: 10.1038/s41467-019-08299-7.

3.

LIPID MAPS: Serving the next generation of lipid researchers with tools, resources, data, and training.

O'Donnell VB, Dennis EA, Wakelam MJO, Subramaniam S.

Sci Signal. 2019 Jan 8;12(563). pii: eaaw2964. doi: 10.1126/scisignal.aaw2964. Review.

4.

Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism Caenorhabditis elegans.

Witting M, Hastings J, Rodriguez N, Joshi CJ, Hattwell JPN, Ebert PR, van Weeghel M, Gao AW, Wakelam MJO, Houtkooper RH, Mains A, Le Novère N, Sadykoff S, Schroeder F, Lewis NE, Schirra HJ, Kaleta C, Casanueva O.

Front Mol Biosci. 2018 Nov 14;5:96. doi: 10.3389/fmolb.2018.00096. eCollection 2018.

5.

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers.

Jones DT, Valli A, Haider S, Zhang Q, Smethurst EA, Schug ZT, Peck B, Aboagye EO, Critchlow SE, Schulze A, Gottlieb E, Wakelam MJO, Harris AL.

Mol Cancer Ther. 2019 Feb;18(2):376-388. doi: 10.1158/1535-7163.MCT-17-0857. Epub 2018 Nov 26.

6.

C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies.

Ezcurra M, Benedetto A, Sornda T, Gilliat AF, Au C, Zhang Q, van Schelt S, Petrache AL, Wang H, Guardia Y, Bar-Nun S, Tyler E, Wakelam MJ, Gems D.

Curr Biol. 2018 Oct 22;28(20):3352. doi: 10.1016/j.cub.2018.10.003. No abstract available.

7.

CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways.

Sadej R, Lu X, Turczyk L, Novitskaya V, Lopez-Clavijo AF, Kordek R, Potemski P, Wakelam MJO, Romanska-Knight H, Berditchevski F.

J Cell Sci. 2018 Oct 29;131(21). pii: jcs220640. doi: 10.1242/jcs.220640.

8.

MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines.

Burla B, Arita M, Arita M, Bendt AK, Cazenave-Gassiot A, Dennis EA, Ekroos K, Han X, Ikeda K, Liebisch G, Lin MK, Loh TP, Meikle PJ, Orešič M, Quehenberger O, Shevchenko A, Torta F, Wakelam MJO, Wheelock CE, Wenk MR.

J Lipid Res. 2018 Oct;59(10):2001-2017. doi: 10.1194/jlr.S087163. Epub 2018 Aug 16.

9.

C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies.

Ezcurra M, Benedetto A, Sornda T, Gilliat AF, Au C, Zhang Q, van Schelt S, Petrache AL, Wang H, de la Guardia Y, Bar-Nun S, Tyler E, Wakelam MJ, Gems D.

Curr Biol. 2018 Aug 20;28(16):2544-2556.e5. doi: 10.1016/j.cub.2018.06.035. Epub 2018 Aug 9. Erratum in: Curr Biol. 2018 Oct 22;28(20):3352.

10.

Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets.

Nguyen A, Guedán A, Mousnier A, Swieboda D, Zhang Q, Horkai D, Le Novere N, Solari R, Wakelam MJO.

J Lipid Res. 2018 Sep;59(9):1671-1684. doi: 10.1194/jlr.M085910. Epub 2018 Jun 26.

11.

Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels.

Riento K, Zhang Q, Clark J, Begum F, Stephens E, Wakelam MJ, Nichols BJ.

PLoS One. 2018 May 22;13(5):e0197401. doi: 10.1371/journal.pone.0197401. eCollection 2018.

12.

Extracellular vesicles: lipids as key components of their biogenesis and functions.

Record M, Silvente-Poirot S, Poirot M, Wakelam MJO.

J Lipid Res. 2018 Aug;59(8):1316-1324. doi: 10.1194/jlr.E086173. Epub 2018 May 15. Review.

13.

Phospholipid signaling in innate immune cells.

O'Donnell VB, Rossjohn J, Wakelam MJ.

J Clin Invest. 2018 Jul 2;128(7):2670-2679. doi: 10.1172/JCI97944. Epub 2018 Apr 23. Review.

14.

Deciphering lipid structures based on platform-independent decision rules.

Hartler J, Triebl A, Ziegl A, Trötzmüller M, Rechberger GN, Zeleznik OA, Zierler KA, Torta F, Cazenave-Gassiot A, Wenk MR, Fauland A, Wheelock CE, Armando AM, Quehenberger O, Zhang Q, Wakelam MJO, Haemmerle G, Spener F, Köfeler HC, Thallinger GG.

Nat Methods. 2017 Dec;14(12):1171-1174. doi: 10.1038/nmeth.4470. Epub 2017 Oct 23.

15.

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.

Hahn O, Grönke S, Stubbs TM, Ficz G, Hendrich O, Krueger F, Andrews S, Zhang Q, Wakelam MJ, Beyer A, Reik W, Partridge L.

Genome Biol. 2017 Mar 28;18(1):56. doi: 10.1186/s13059-017-1187-1.

16.

Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.

Farquhar MJ, Humphreys IS, Rudge SA, Wilson GK, Bhattacharya B, Ciaccia M, Hu K, Zhang Q, Mailly L, Reynolds GM, Ashcroft M, Balfe P, Baumert TF, Roessler S, Wakelam MJO, McKeating JA.

J Hepatol. 2017 May;66(5):919-929. doi: 10.1016/j.jhep.2017.01.009. Epub 2017 Jan 23.

PMID:
28126468
17.

Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis.

Kilbey A, Terry A, Wotton S, Borland G, Zhang Q, Mackay N, McDonald A, Bell M, Wakelam MJ, Cameron ER, Neil JC.

J Cell Biochem. 2017 Jun;118(6):1432-1441. doi: 10.1002/jcb.25802. Epub 2017 Jan 10.

18.

Phospholipase D activity couples plasma membrane endocytosis with retromer dependent recycling.

Thakur R, Panda A, Coessens E, Raj N, Yadav S, Balakrishnan S, Zhang Q, Georgiev P, Basak B, Pasricha R, Wakelam MJ, Ktistakis NT, Raghu P.

Elife. 2016 Nov 16;5. pii: e18515. doi: 10.7554/eLife.18515.

19.

Using lipidomics analysis to determine signalling and metabolic changes in cells.

Nguyen A, Rudge SA, Zhang Q, Wakelam MJ.

Curr Opin Biotechnol. 2017 Feb;43:96-103. doi: 10.1016/j.copbio.2016.10.003. Epub 2016 Nov 4. Review.

PMID:
27816901
20.

Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations.

Huang-Doran I, Tomlinson P, Payne F, Gast A, Sleigh A, Bottomley W, Harris J, Daly A, Rocha N, Rudge S, Clark J, Kwok A, Romeo S, McCann E, Müksch B, Dattani M, Zucchini S, Wakelam M, Foukas LC, Savage DB, Murphy R, O'Rahilly S, Barroso I, Semple RK.

JCI Insight. 2016 Oct 20;1(17):e88766. doi: 10.1172/jci.insight.88766.

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