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Pragmatic randomised controlled trial of very early etanercept and MTX versus MTX with delayed etanercept in RA: the VEDERA trial.

Emery P, Horton S, Dumitru RB, Naraghi K, van der Heijde D, Wakefield RJ, Hensor EMA, Buch MH.

Ann Rheum Dis. 2020 Apr;79(4):464-471. doi: 10.1136/annrheumdis-2019-216539. Epub 2020 Jan 29.


'Slope sign': a feature of large vessel vasculitis?

Dasgupta B, Smith K, Khan AAS, Coath F, Wakefield RJ.

Ann Rheum Dis. 2019 Dec;78(12):1738. doi: 10.1136/annrheumdis-2019-216213. Epub 2019 Sep 13. No abstract available.


Reduction in stiffness of proximal leg muscles during the first 6 months of glucocorticoid therapy for giant cell arteritis: A pilot study using shear wave elastography.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Mackie S, Wakefield RJ.

Int J Rheum Dis. 2019 Oct;22(10):1891-1899. doi: 10.1111/1756-185X.13667. Epub 2019 Jul 30.


Reply to: Graduate-entry medical students' perspectives on the development of ultrasound teaching in UK Medical schools.

Wakefield RJ, Weerasinghe A, Tung P, Smith L, Roberts T.

Med Teach. 2020 Mar;42(3):358-359. doi: 10.1080/0142159X.2019.1643585. Epub 2019 Jul 26. No abstract available.


Muscle stiffness in rheumatoid arthritis is not altered or associated with muscle weakness: A shear wave elastography study.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Mod Rheumatol. 2019 Aug 1:1-9. doi: 10.1080/14397595.2019.1645374. [Epub ahead of print]


Development of semiquantitative ultrasound scoring system to assess cartilage in rheumatoid arthritis.

Mandl P, Studenic P, Filippucci E, Bachta A, Backhaus M, Bong D, Bruyn GAW, Collado P, Damjanov N, Dejaco C, Delle-Sedie A, De Miguel E, Duftner C, Gessl I, Gutierrez M, Hammer HB, Hernandez-Diaz C, Iagnocco A, Ikeda K, Kane D, Keen H, Kelly S, Kővári E, Möller I, Møller-Dohn U, Naredo E, Nieto JC, Pineda C, Platzer A, Rodriguez A, Schmidt WA, Supp G, Szkudlarek M, Terslev L, Thiele R, Wakefield RJ, Windschall D, D'Agostino MA, Balint PV; OMERACT Ultrasound Cartilage Task Force Group.

Rheumatology (Oxford). 2019 Oct 1;58(10):1802-1811. doi: 10.1093/rheumatology/kez153. Review.


The OMERACT Stepwise Approach to Select and Develop Imaging Outcome Measurement Instruments: The Musculoskeletal Ultrasound Example.

Terslev L, Naredo E, Keen HI, Bruyn GAW, Iagnocco A, Wakefield RJ, Conaghan PG, Maxwell LJ, Beaton DE, Boers M, D'Agostino MA.

J Rheumatol. 2019 Oct;46(10):1394-1400. doi: 10.3899/jrheum.181158. Epub 2019 Mar 15.


Muscle shear wave elastography in idiopathic inflammatory myopathies: a case-control study with MRI correlation.

Alfuraih AM, O'Connor P, Tan AL, Hensor EMA, Ladas A, Emery P, Wakefield RJ.

Skeletal Radiol. 2019 Aug;48(8):1209-1219. doi: 10.1007/s00256-019-03175-3. Epub 2019 Feb 27.


The effect of ageing on shear wave elastography muscle stiffness in adults.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Aging Clin Exp Res. 2019 Dec;31(12):1755-1763. doi: 10.1007/s40520-019-01139-0. Epub 2019 Feb 14.


OMERACT Definitions for Ultrasonographic Pathologies and Elementary Lesions of Rheumatic Disorders 15 Years On.

Bruyn GA, Iagnocco A, Naredo E, Balint PV, Gutierrez M, Hammer HB, Collado P, Filippou G, Schmidt WA, Jousse-Joulin S, Mandl P, Conaghan PG, Wakefield RJ, Keen HI, Terslev L, D'Agostino MA; OMERACT Ultrasound Working Group.

J Rheumatol. 2019 Oct;46(10):1388-1393. doi: 10.3899/jrheum.181095. Epub 2019 Feb 1.


Ultrasound of Subtalar Joint Synovitis in Patients with Rheumatoid Arthritis: Results of an OMERACT Reliability Exercise Using Consensual Definitions.

Bruyn GAW, Siddle HJ, Hanova P, Costantino F, Iagnocco A, Sedie AD, Gutierrez M, Hammer HB, Jernberg E, Loeille D, Micu MC, Moller I, Pineda C, Richards B, Stoenoiu MS, Suzuki T, Terslev L, Vlad V, Wonink R, d'Agostino MA, Wakefield RJ.

J Rheumatol. 2019 Apr;46(4):351-359. doi: 10.3899/jrheum.171490. Epub 2018 Nov 1. Erratum in: J Rheumatol. 2019 Jul;46(7):867.


Identification of a distinct imaging phenotype may improve the management of palindromic rheumatism.

Mankia K, D'Agostino MA, Wakefield RJ, Nam JL, Mahmood W, Grainger AJ, Emery P.

Ann Rheum Dis. 2019 Jan;78(1):43-50. doi: 10.1136/annrheumdis-2018-214175. Epub 2018 Oct 8.


Defining inflammatory musculoskeletal manifestations in systemic lupus erythematosus.

Zayat AS, Mahmoud K, Md Yusof MY, Mukherjee S, D'Agostino MA, Hensor EMA, Wakefield RJ, Conaghan PG, Edwards CJ, Emery P, Vital EM.

Rheumatology (Oxford). 2019 Feb 1;58(2):304-312. doi: 10.1093/rheumatology/key277.


Reliability of a consensus-based ultrasound definition and scoring for enthesitis in spondyloarthritis and psoriatic arthritis: an OMERACT US initiative.

Balint PV, Terslev L, Aegerter P, Bruyn GAW, Chary-Valckenaere I, Gandjbakhch F, Iagnocco A, Jousse-Joulin S, Möller I, Naredo E, Schmidt WA, Wakefield RJ, D'Agostino MA; OMERACT Ultrasound Task Force members.

Ann Rheum Dis. 2018 Dec;77(12):1730-1735. doi: 10.1136/annrheumdis-2018-213609. Epub 2018 Aug 3.


The development of a pragmatic, clinically driven ultrasound curriculum in a UK medical school.

Wakefield RJ, Weerasinghe A, Tung P, Smith L, Pickering J, Msimanga T, Arora M, Flood K, Gupta P, Bickerdike S, McLaughlan J, Uttley A, Wilson J, Evans T, Wolstenhulme S, Roberts TE.

Med Teach. 2018 Jun;40(6):600-606. doi: 10.1080/0142159X.2018.1439579. Epub 2018 Feb 28.


Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial.

Kingsbury SR, Tharmanathan P, Keding A, Ronaldson SJ, Grainger A, Wakefield RJ, Arundel C, Birrell F, Doherty M, Vincent T, Watt FE, Dziedzic K, O'Neill TW, Arden NK, Scott DL, Dickson J, Garrood T, Green M, Menon A, Sheeran T, Torgerson D, Conaghan PG.

Ann Intern Med. 2018 Mar 20;168(6):385-395. doi: 10.7326/M17-1430. Epub 2018 Feb 20.


An investigation into the variability between different shear wave elastography systems in muscle.

Alfuraih AM, O'Connor P, Tan AL, Hensor E, Emery P, Wakefield RJ.

Med Ultrason. 2017 Nov 29;19(4):392-400. doi: 10.11152/mu-1113.


The effect of unit, depth, and probe load on the reliability of muscle shear wave elastography: Variables affecting reliability of SWE.

Alfuraih AM, O'Connor P, Hensor E, Tan AL, Emery P, Wakefield RJ.

J Clin Ultrasound. 2018 Feb;46(2):108-115. doi: 10.1002/jcu.22534. Epub 2017 Oct 9.


Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 2: reliability and application to multiple joints of a standardised consensus-based scoring system.

Terslev L, Naredo E, Aegerter P, Wakefield RJ, Backhaus M, Balint P, Bruyn GAW, Iagnocco A, Jousse-Joulin S, Schmidt WA, Szkudlarek M, Conaghan PG, Filippucci E, D'Agostino MA.

RMD Open. 2017 Jul 11;3(1):e000427. doi: 10.1136/rmdopen-2016-000427. eCollection 2017.


Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 1: definition and development of a standardised, consensus-based scoring system.

D'Agostino MA, Terslev L, Aegerter P, Backhaus M, Balint P, Bruyn GA, Filippucci E, Grassi W, Iagnocco A, Jousse-Joulin S, Kane D, Naredo E, Schmidt W, Szkudlarek M, Conaghan PG, Wakefield RJ.

RMD Open. 2017 Jul 11;3(1):e000428. doi: 10.1136/rmdopen-2016-000428. eCollection 2017.


Plantar plate pathology is associated with erosive disease in the painful forefoot of patients with rheumatoid arthritis.

Siddle HJ, Hodgson RJ, Hensor EMA, Grainger AJ, Redmond AC, Wakefield RJ, Helliwell PS.

BMC Musculoskelet Disord. 2017 Jul 18;18(1):308. doi: 10.1186/s12891-017-1668-0.


The new ACR/EULAR criteria for rheumatoid arthritis can identify patients with same disease activity but less damage by ultrasound.

Aydın SZ, Castillo-Gallego C, Nam J, Freeston J, Horton S, Wakefield RJ, Emery P.

Eur J Rheumatol. 2017 Jun;4(2):118-121. doi: 10.5152/eurjrheum.2017.160091. Epub 2017 Jun 1.


Ultrasound-detectable grey scale synovitis predicts future fulfilment of the 2010 ACR/EULAR RA classification criteria in patients with new-onset undifferentiated arthritis.

Horton SC, Tan AL, Wakefield RJ, Freeston JE, Buch MH, Emery P.

RMD Open. 2017 Mar 30;3(1):e000394. doi: 10.1136/rmdopen-2016-000394. eCollection 2017.


Diagnostic test accuracy of ultrasound for synovitis in rheumatoid arthritis: systematic review and meta-analysis.

Takase-Minegishi K, Horita N, Kobayashi K, Yoshimi R, Kirino Y, Ohno S, Kaneko T, Nakajima H, Wakefield RJ, Emery P.

Rheumatology (Oxford). 2018 Jan 1;57(1):49-58. doi: 10.1093/rheumatology/kex036. Review.


Abatacept reduces disease activity and ultrasound power Doppler in ACPA-negative undifferentiated arthritis: a proof-of-concept clinical and imaging study.

Buch MH, Hensor EM, Rakieh C, Freeston JE, Middleton E, Horton S, Das S, Peterfy C, Tan AL, Wakefield RJ, Emery P.

Rheumatology (Oxford). 2017 Jan;56(1):58-67. doi: 10.1093/rheumatology/kew357. Epub 2016 Oct 22.


The EULAR points to consider for health professionals undertaking musculoskeletal ultrasound for rheumatic and musculoskeletal diseases.

Siddle HJ, Mandl P, Aletaha D, Vliet Vlieland TP, Backhaus M, Cornell P, D'Agostino MA, Ellegaard K, Iagnocco A, Jakobsen B, Jasinski T, Kildal NH, Lehner M, Möller I, Supp GM, O'Connor P, Redmond AC, Naredo E, Wakefield RJ.

Ann Rheum Dis. 2018 Feb;77(2):311-313. doi: 10.1136/annrheumdis-2016-210741. Epub 2016 Dec 9. No abstract available.


Is it time to revisit the role of ultrasound in rheumatoid arthritis management?

D'Agostino MA, Boers M, Wakefield RJ, Emery P, Conaghan PG.

Ann Rheum Dis. 2017 Jan;76(1):7-8. doi: 10.1136/annrheumdis-2016-210453. Epub 2016 Nov 9.


Exploring a new ultrasound score as a clinical predictive tool in patients with rheumatoid arthritis starting abatacept: results from the APPRAISE study.

D'Agostino MA, Boers M, Wakefield RJ, Berner Hammer H, Vittecoq O, Filippou G, Balint P, Möller I, Iagnocco A, Naredo E, Østergaard M, Gaillez C, Le Bars M.

RMD Open. 2016 May 5;2(1):e000237. doi: 10.1136/rmdopen-2015-000237. eCollection 2016.


Discordance between the predictors of clinical and imaging remission in patients with early rheumatoid arthritis in clinical practice: implications for the use of ultrasound within a treatment-to-target strategy.

Horton SC, Tan AL, Freeston JE, Wakefield RJ, Buch MH, Emery P.

Rheumatology (Oxford). 2016 Jul;55(7):1177-87. doi: 10.1093/rheumatology/kew037. Epub 2016 Mar 19.


A prospective, single-centre, randomised study evaluating the clinical, imaging and immunological depth of remission achieved by very early versus delayed Etanercept in patients with Rheumatoid Arthritis (VEDERA).

Dumitru RB, Horton S, Hodgson R, Wakefield RJ, Hensor EMA, Emery P, Buch MH.

BMC Musculoskelet Disord. 2016 Feb 5;17:61. doi: 10.1186/s12891-016-0915-0.


Ultrasound findings predict progression to inflammatory arthritis in anti-CCP antibody-positive patients without clinical synovitis.

Nam JL, Hensor EM, Hunt L, Conaghan PG, Wakefield RJ, Emery P.

Ann Rheum Dis. 2016 Dec;75(12):2060-2067. doi: 10.1136/annrheumdis-2015-208235. Epub 2016 Jan 22.


Summary Findings of a Systematic Literature Review of the Ultrasound Assessment of Bone Erosions in Rheumatoid Arthritis.

Szkudlarek M, Terslev L, Wakefield RJ, Backhaus M, Balint PV, Bruyn GA, Filippucci E, Gandjbakhch F, Iagnocco A, Mandl P, Möller I, Naredo E, Schmidt WA, d'Agostino MA.

J Rheumatol. 2016 Jan;43(1):12-21. doi: 10.3899/jrheum.141416. Epub 2015 Dec 1. Review. Erratum in: J Rheumatol. 2017 Jan;44(1):130.


Value of ultrasonography as a marker of early response to abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results from the APPRAISE study.

D'Agostino MA, Wakefield RJ, Berner-Hammer H, Vittecoq O, Filippou G, Balint P, Möller I, Iagnocco A, Naredo E, Østergaard M, Boers M, Gaillez C, Van Holder K, Le Bars M; OMERACT-EULAR-Ultrasound Task Force.

Ann Rheum Dis. 2016 Oct;75(10):1763-9. doi: 10.1136/annrheumdis-2015-207709. Epub 2015 Nov 20.


Educational recommendations for the conduct, content and format of EULAR musculoskeletal ultrasound Teaching the Teachers Courses.

Iagnocco A, Terslev L, Backhaus M, Balint P, Bruyn GA, Damjanov N, Filippucci E, Hammer HB, Jousse-Joulin S, Kane D, Koski JM, Mandl P, Möller I, Peetrons P, Schmidt W, Szkudlarek M, Vojinovic J, Wakefield RJ, Hofer M, D'Agostino MA, Naredo E.

RMD Open. 2015 Oct 6;1(1):e000139. doi: 10.1136/rmdopen-2015-000139. eCollection 2015.


Accuracy of musculoskeletal imaging for the diagnosis of polymyalgia rheumatica: systematic review.

Mackie SL, Koduri G, Hill CL, Wakefield RJ, Hutchings A, Loy C, Dasgupta B, Wyatt JC.

RMD Open. 2015 Aug 13;1(1):e000100. doi: 10.1136/rmdopen-2015-000100. eCollection 2015.


The role of ultrasound in assessing musculoskeletal symptoms of systemic lupus erythematosus: a systematic literature review.

Zayat AS, Md Yusof MY, Wakefield RJ, Conaghan PG, Emery P, Vital EM.

Rheumatology (Oxford). 2016 Mar;55(3):485-94. doi: 10.1093/rheumatology/kev343. Epub 2015 Oct 7. Review.


Reply: To PMID 25370843.

Torp-Pedersen S, Christensen R, Ellegaard K, Torp-Pedersen A, Szkudlarek M, D'Agostino MA, Iagnocco A, Naredo E, Balint P, Wakefield RJ, Terslev L, Jensen JA.

Arthritis Rheumatol. 2015 Jun;67(6):1681-3. doi: 10.1002/art.39057. No abstract available.


Ultrasound assessment of response to intra-articular therapy in osteoarthritis of the knee.

Keen HI, Hensor EM, Wakefield RJ, Mease PJ, Bingham CO 3rd, Conaghan PG.

Rheumatology (Oxford). 2015 Aug;54(8):1385-91. doi: 10.1093/rheumatology/keu529. Epub 2015 Feb 16.


Global ultrasound assessment of structural lesions in osteoarthritis: a reliability study by the OMERACT ultrasonography group on scoring cartilage and osteophytes in finger joints.

Hammer HB, Iagnocco A, Mathiessen A, Filippucci E, Gandjbakhch F, Kortekaas MC, Möller I, Naredo E, Wakefield RJ, Aegerter P, D'Agostino MA.

Ann Rheum Dis. 2016 Feb;75(2):402-7. doi: 10.1136/annrheumdis-2014-206289. Epub 2014 Dec 17.


Power and color Doppler ultrasound settings for inflammatory flow: impact on scoring of disease activity in patients with rheumatoid arthritis.

Torp-Pedersen S, Christensen R, Szkudlarek M, Ellegaard K, D'Agostino MA, Iagnocco A, Naredo E, Balint P, Wakefield RJ, Torp-Pedersen A, Terslev L.

Arthritis Rheumatol. 2015 Feb;67(2):386-95. doi: 10.1002/art.38940.


Musculoskeletal ultrasound in rheumatology in Korea: targeted ultrasound initiative survey.

Kang T, Wakefield RJ, Emery P.

Int J Rheum Dis. 2016 Apr;19(4):335-42. doi: 10.1111/1756-185X.12508. Epub 2014 Oct 28.


Skin imaging in systemic sclerosis.

Kang T, Abignano G, Lettieri G, Wakefield RJ, Emery P, Del Galdo F.

Eur J Rheumatol. 2014 Sep;1(3):111-116. Epub 2014 Sep 1. Review.


Predicting the development of clinical arthritis in anti-CCP positive individuals with non-specific musculoskeletal symptoms: a prospective observational cohort study.

Rakieh C, Nam JL, Hunt L, Hensor EM, Das S, Bissell LA, Villeneuve E, McGonagle D, Hodgson R, Grainger A, Wakefield RJ, Conaghan PG, Emery P.

Ann Rheum Dis. 2015 Sep;74(9):1659-66. doi: 10.1136/annrheumdis-2014-205227. Epub 2014 Apr 12.


A randomised controlled trial of etanercept and methotrexate to induce remission in early inflammatory arthritis: the EMPIRE trial.

Nam JL, Villeneuve E, Hensor EM, Wakefield RJ, Conaghan PG, Green MJ, Gough A, Quinn M, Reece R, Cox SR, Buch MH, van der Heijde DM, Emery P.

Ann Rheum Dis. 2014 Jun;73(6):1027-36. doi: 10.1136/annrheumdis-2013-204882. Epub 2014 Mar 11.


Updating the OMERACT filter: implications for imaging and soluble biomarkers.

D'Agostino MA, Boers M, Kirwan J, van der Heijde D, Østergaard M, Schett G, Landewé RB, Maksymowych WP, Naredo E, Dougados M, Iagnocco A, Bingham CO 3rd, Brooks PM, Beaton DE, Gandjbakhch F, Gossec L, Guillemin F, Hewlett SE, Kloppenburg M, March L, Mease PJ, Moller I, Simon LS, Singh JA, Strand V, Wakefield RJ, Wells GA, Tugwell P, Conaghan PG.

J Rheumatol. 2014 May;41(5):1016-24. doi: 10.3899/jrheum.131313. Epub 2014 Mar 1.


A brief history of ultrasound in rheumatology: where we are now.

Kang T, Emery P, Wakefield RJ.

Clin Exp Rheumatol. 2014 Jan-Feb;32(1 Suppl 80):S7-11. Epub 2014 Feb 17. Review.


Anatomical location of erosions at the metatarsophalangeal joints in patients with rheumatoid arthritis.

Siddle HJ, Hensor EM, Hodgson RJ, Grainger AJ, Redmond AC, Wakefield RJ, Helliwell PS.

Rheumatology (Oxford). 2014 May;53(5):932-6. doi: 10.1093/rheumatology/ket478. Epub 2014 Jan 29.


The specificity of ultrasound-detected bone erosions for rheumatoid arthritis.

Zayat AS, Ellegaard K, Conaghan PG, Terslev L, Hensor EM, Freeston JE, Emery P, Wakefield RJ.

Ann Rheum Dis. 2015 May;74(5):897-903. doi: 10.1136/annrheumdis-2013-204864. Epub 2014 Jan 20.


Defining enthesitis in spondyloarthritis by ultrasound: results of a Delphi process and of a reliability reading exercise.

Terslev L, Naredo E, Iagnocco A, Balint PV, Wakefield RJ, Aegerter P, Aydin SZ, Bachta A, Hammer HB, Bruyn GA, Filippucci E, Gandjbakhch F, Mandl P, Pineda C, Schmidt WA, D'Agostino MA; Outcome Measures in Rheumatology Ultrasound Task Force.

Arthritis Care Res (Hoboken). 2014 May;66(5):741-8. doi: 10.1002/acr.22191. Erratum in: Arthritis Care Res (Hoboken). 2017 Feb;69(2):311.


Is there subclinical synovitis in early psoriatic arthritis? A clinical comparison with gray-scale and power Doppler ultrasound.

Freeston JE, Coates LC, Nam JL, Moverley AR, Hensor EM, Wakefield RJ, Emery P, Helliwell PS, Conaghan PG.

Arthritis Care Res (Hoboken). 2014 Mar;66(3):432-9. doi: 10.1002/acr.22158.

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