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'Slope sign': a feature of large vessel vasculitis?

Dasgupta B, Smith K, Khan AAS, Coath F, Wakefield RJ.

Ann Rheum Dis. 2019 Sep 13. pii: annrheumdis-2019-216213. doi: 10.1136/annrheumdis-2019-216213. [Epub ahead of print] No abstract available.


Reduction in stiffness of proximal leg muscles during the first 6 months of glucocorticoid therapy for giant cell arteritis: A pilot study using shear wave elastography.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Mackie S, Wakefield RJ.

Int J Rheum Dis. 2019 Jul 30. doi: 10.1111/1756-185X.13667. [Epub ahead of print]


Reply to: Graduate-entry medical students' perspectives on the development of ultrasound teaching in UK Medical schools.

Wakefield RJ, Weerasinghe A, Tung P, Smith L, Roberts T.

Med Teach. 2019 Jul 26:1-2. doi: 10.1080/0142159X.2019.1643585. [Epub ahead of print] No abstract available.


Muscle stiffness in rheumatoid arthritis is not altered or associated with muscle weakness: A shear wave elastography study.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Mod Rheumatol. 2019 Aug 1:1-9. doi: 10.1080/14397595.2019.1645374. [Epub ahead of print]


Development of semiquantitative ultrasound scoring system to assess cartilage in rheumatoid arthritis.

Mandl P, Studenic P, Filippucci E, Bachta A, Backhaus M, Bong D, Bruyn GAW, Collado P, Damjanov N, Dejaco C, Delle-Sedie A, De Miguel E, Duftner C, Gessl I, Gutierrez M, Hammer HB, Hernandez-Diaz C, Iagnocco A, Ikeda K, Kane D, Keen H, Kelly S, Kővári E, Möller I, Møller-Dohn U, Naredo E, Nieto JC, Pineda C, Platzer A, Rodriguez A, Schmidt WA, Supp G, Szkudlarek M, Terslev L, Thiele R, Wakefield RJ, Windschall D, D'Agostino MA, Balint PV; OMERACT Ultrasound Cartilage Task Force Group.

Rheumatology (Oxford). 2019 Oct 1;58(10):1802-1811. doi: 10.1093/rheumatology/kez153.


The OMERACT Stepwise Approach to Select and Develop Imaging Outcome Measurement Instruments: The Musculoskeletal Ultrasound Example.

Terslev L, Naredo E, Keen HI, Bruyn GAW, Iagnocco A, Wakefield RJ, Conaghan PG, Maxwell LJ, Beaton DE, Boers M, D'Agostino MA.

J Rheumatol. 2019 Oct;46(10):1394-1400. doi: 10.3899/jrheum.181158. Epub 2019 Mar 15.


Muscle shear wave elastography in idiopathic inflammatory myopathies: a case-control study with MRI correlation.

Alfuraih AM, O'Connor P, Tan AL, Hensor EMA, Ladas A, Emery P, Wakefield RJ.

Skeletal Radiol. 2019 Aug;48(8):1209-1219. doi: 10.1007/s00256-019-03175-3. Epub 2019 Feb 27.


The effect of ageing on shear wave elastography muscle stiffness in adults.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Aging Clin Exp Res. 2019 Feb 14. doi: 10.1007/s40520-019-01139-0. [Epub ahead of print]


OMERACT Definitions for Ultrasonographic Pathologies and Elementary Lesions of Rheumatic Disorders 15 Years On.

Bruyn GA, Iagnocco A, Naredo E, Balint PV, Gutierrez M, Hammer HB, Collado P, Filippou G, Schmidt WA, Jousse-Joulin S, Mandl P, Conaghan PG, Wakefield RJ, Keen HI, Terslev L, D'Agostino MA; OMERACT Ultrasound Working Group.

J Rheumatol. 2019 Oct;46(10):1388-1393. doi: 10.3899/jrheum.181095. Epub 2019 Feb 1.


Regression of Peripheral Subclinical Enthesopathy in Therapy-Naive Patients Treated With Ustekinumab for Moderate-to-Severe Chronic Plaque Psoriasis: A Fifty-Two-Week, Prospective, Open-Label Feasibility Study.

Savage L, Goodfield M, Horton L, Watad A, Hensor E, Emery P, Wakefield R, Wittmann M, McGonagle D.

Arthritis Rheumatol. 2019 Apr;71(4):626-631. doi: 10.1002/art.40778. Epub 2019 Mar 4.


Ultrasound of Subtalar Joint Synovitis in Patients with Rheumatoid Arthritis: Results of an OMERACT Reliability Exercise Using Consensual Definitions.

Bruyn GAW, Siddle HJ, Hanova P, Costantino F, Iagnocco A, Sedie AD, Gutierrez M, Hammer HB, Jernberg E, Loeille D, Micu MC, Moller I, Pineda C, Richards B, Stoenoiu MS, Suzuki T, Terslev L, Vlad V, Wonink R, d'Agostino MA, Wakefield RJ.

J Rheumatol. 2019 Apr;46(4):351-359. doi: 10.3899/jrheum.171490. Epub 2018 Nov 1. Erratum in: J Rheumatol. 2019 Jul;46(7):867.


Identification of a distinct imaging phenotype may improve the management of palindromic rheumatism.

Mankia K, D'Agostino MA, Wakefield RJ, Nam JL, Mahmood W, Grainger AJ, Emery P.

Ann Rheum Dis. 2019 Jan;78(1):43-50. doi: 10.1136/annrheumdis-2018-214175. Epub 2018 Oct 8.


Defining inflammatory musculoskeletal manifestations in systemic lupus erythematosus.

Zayat AS, Mahmoud K, Md Yusof MY, Mukherjee S, D'Agostino MA, Hensor EMA, Wakefield RJ, Conaghan PG, Edwards CJ, Emery P, Vital EM.

Rheumatology (Oxford). 2019 Feb 1;58(2):304-312. doi: 10.1093/rheumatology/key277.


Reliability of a consensus-based ultrasound definition and scoring for enthesitis in spondyloarthritis and psoriatic arthritis: an OMERACT US initiative.

Balint PV, Terslev L, Aegerter P, Bruyn GAW, Chary-Valckenaere I, Gandjbakhch F, Iagnocco A, Jousse-Joulin S, Möller I, Naredo E, Schmidt WA, Wakefield RJ, D'Agostino MA; OMERACT Ultrasound Task Force members.

Ann Rheum Dis. 2018 Dec;77(12):1730-1735. doi: 10.1136/annrheumdis-2018-213609. Epub 2018 Aug 3.


What is the added value of ultrasound joint examination for monitoring synovitis in rheumatoid arthritis and can it be used to guide treatment decisions? A systematic review and cost-effectiveness analysis.

Simpson E, Hock E, Stevenson M, Wong R, Dracup N, Wailoo A, Conaghan P, Estrach C, Edwards C, Wakefield R.

Health Technol Assess. 2018 Apr;22(20):1-258. doi: 10.3310/hta22200. Review.


The development of a pragmatic, clinically driven ultrasound curriculum in a UK medical school.

Wakefield RJ, Weerasinghe A, Tung P, Smith L, Pickering J, Msimanga T, Arora M, Flood K, Gupta P, Bickerdike S, McLaughlan J, Uttley A, Wilson J, Evans T, Wolstenhulme S, Roberts TE.

Med Teach. 2018 Jun;40(6):600-606. doi: 10.1080/0142159X.2018.1439579. Epub 2018 Feb 28.


Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial.

Kingsbury SR, Tharmanathan P, Keding A, Ronaldson SJ, Grainger A, Wakefield RJ, Arundel C, Birrell F, Doherty M, Vincent T, Watt FE, Dziedzic K, O'Neill TW, Arden NK, Scott DL, Dickson J, Garrood T, Green M, Menon A, Sheeran T, Torgerson D, Conaghan PG.

Ann Intern Med. 2018 Mar 20;168(6):385-395. doi: 10.7326/M17-1430. Epub 2018 Feb 20.


An investigation into the variability between different shear wave elastography systems in muscle.

Alfuraih AM, O'Connor P, Tan AL, Hensor E, Emery P, Wakefield RJ.

Med Ultrason. 2017 Nov 29;19(4):392-400. doi: 10.11152/mu-1113.


The effect of unit, depth, and probe load on the reliability of muscle shear wave elastography: Variables affecting reliability of SWE.

Alfuraih AM, O'Connor P, Hensor E, Tan AL, Emery P, Wakefield RJ.

J Clin Ultrasound. 2018 Feb;46(2):108-115. doi: 10.1002/jcu.22534. Epub 2017 Oct 9.


Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 2: reliability and application to multiple joints of a standardised consensus-based scoring system.

Terslev L, Naredo E, Aegerter P, Wakefield RJ, Backhaus M, Balint P, Bruyn GAW, Iagnocco A, Jousse-Joulin S, Schmidt WA, Szkudlarek M, Conaghan PG, Filippucci E, D'Agostino MA.

RMD Open. 2017 Jul 11;3(1):e000427. doi: 10.1136/rmdopen-2016-000427. eCollection 2017.


Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 1: definition and development of a standardised, consensus-based scoring system.

D'Agostino MA, Terslev L, Aegerter P, Backhaus M, Balint P, Bruyn GA, Filippucci E, Grassi W, Iagnocco A, Jousse-Joulin S, Kane D, Naredo E, Schmidt W, Szkudlarek M, Conaghan PG, Wakefield RJ.

RMD Open. 2017 Jul 11;3(1):e000428. doi: 10.1136/rmdopen-2016-000428. eCollection 2017.


The 2017 EULAR standardised procedures for ultrasound imaging in rheumatology.

Möller I, Janta I, Backhaus M, Ohrndorf S, Bong DA, Martinoli C, Filippucci E, Sconfienza LM, Terslev L, Damjanov N, Hammer HB, Sudol-Szopinska I, Grassi W, Balint P, Bruyn GAW, D'Agostino MA, Hollander D, Siddle HJ, Supp G, Schmidt WA, Iagnocco A, Koski J, Kane D, Fodor D, Bruns A, Mandl P, Kaeley GS, Micu M, Ho C, Vlad V, Chávez-López M, Filippou G, Cerón CE, Nestorova R, Quintero M, Wakefield R, Carmona L, Naredo E.

Ann Rheum Dis. 2017 Dec;76(12):1974-1979. doi: 10.1136/annrheumdis-2017-211585. Epub 2017 Aug 16.


Plantar plate pathology is associated with erosive disease in the painful forefoot of patients with rheumatoid arthritis.

Siddle HJ, Hodgson RJ, Hensor EMA, Grainger AJ, Redmond AC, Wakefield RJ, Helliwell PS.

BMC Musculoskelet Disord. 2017 Jul 18;18(1):308. doi: 10.1186/s12891-017-1668-0.


The new ACR/EULAR criteria for rheumatoid arthritis can identify patients with same disease activity but less damage by ultrasound.

Aydın SZ, Castillo-Gallego C, Nam J, Freeston J, Horton S, Wakefield RJ, Emery P.

Eur J Rheumatol. 2017 Jun;4(2):118-121. doi: 10.5152/eurjrheum.2017.160091. Epub 2017 Jun 1.


Vascularity of nail bed by ultrasound to discriminate psoriasis, psoriatic arthritis and healthy controls.

Aydin SZ, Castillo-Gallego C, Ash ZR, Marzo-Ortega H, Wakefield R, McGonagle D.

Clin Exp Rheumatol. 2017 Sep-Oct;35(5):872. Epub 2017 Jun 16. No abstract available.


Ultrasound-detectable grey scale synovitis predicts future fulfilment of the 2010 ACR/EULAR RA classification criteria in patients with new-onset undifferentiated arthritis.

Horton SC, Tan AL, Wakefield RJ, Freeston JE, Buch MH, Emery P.

RMD Open. 2017 Mar 30;3(1):e000394. doi: 10.1136/rmdopen-2016-000394. eCollection 2017.


Diagnostic test accuracy of ultrasound for synovitis in rheumatoid arthritis: systematic review and meta-analysis.

Takase-Minegishi K, Horita N, Kobayashi K, Yoshimi R, Kirino Y, Ohno S, Kaneko T, Nakajima H, Wakefield RJ, Emery P.

Rheumatology (Oxford). 2018 Jan 1;57(1):49-58. doi: 10.1093/rheumatology/kex036. Review.


Abatacept reduces disease activity and ultrasound power Doppler in ACPA-negative undifferentiated arthritis: a proof-of-concept clinical and imaging study.

Buch MH, Hensor EM, Rakieh C, Freeston JE, Middleton E, Horton S, Das S, Peterfy C, Tan AL, Wakefield RJ, Emery P.

Rheumatology (Oxford). 2017 Jan;56(1):58-67. doi: 10.1093/rheumatology/kew357. Epub 2016 Oct 22.


The EULAR points to consider for health professionals undertaking musculoskeletal ultrasound for rheumatic and musculoskeletal diseases.

Siddle HJ, Mandl P, Aletaha D, Vliet Vlieland TP, Backhaus M, Cornell P, D'Agostino MA, Ellegaard K, Iagnocco A, Jakobsen B, Jasinski T, Kildal NH, Lehner M, Möller I, Supp GM, O'Connor P, Redmond AC, Naredo E, Wakefield RJ.

Ann Rheum Dis. 2018 Feb;77(2):311-313. doi: 10.1136/annrheumdis-2016-210741. Epub 2016 Dec 9. No abstract available.


Is it time to revisit the role of ultrasound in rheumatoid arthritis management?

D'Agostino MA, Boers M, Wakefield RJ, Emery P, Conaghan PG.

Ann Rheum Dis. 2017 Jan;76(1):7-8. doi: 10.1136/annrheumdis-2016-210453. Epub 2016 Nov 9.


Novel algorithms for the pragmatic use of ultrasound in the management of patients with rheumatoid arthritis: from diagnosis to remission.

D'Agostino MA, Terslev L, Wakefield R, Østergaard M, Balint P, Naredo E, Iagnocco A, Backhaus M, Grassi W, Emery P.

Ann Rheum Dis. 2016 Nov;75(11):1902-1908. doi: 10.1136/annrheumdis-2016-209646. Epub 2016 Aug 23. Review.


Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier.

Campos Y, Qiu X, Gomero E, Wakefield R, Horner L, Brutkowski W, Han YG, Solecki D, Frase S, Bongiovanni A, d'Azzo A.

Nat Commun. 2016 Jun 23;7:11876. doi: 10.1038/ncomms11876.


Exploring a new ultrasound score as a clinical predictive tool in patients with rheumatoid arthritis starting abatacept: results from the APPRAISE study.

D'Agostino MA, Boers M, Wakefield RJ, Berner Hammer H, Vittecoq O, Filippou G, Balint P, Möller I, Iagnocco A, Naredo E, Østergaard M, Gaillez C, Le Bars M.

RMD Open. 2016 May 5;2(1):e000237. doi: 10.1136/rmdopen-2015-000237. eCollection 2016.


Discordance between the predictors of clinical and imaging remission in patients with early rheumatoid arthritis in clinical practice: implications for the use of ultrasound within a treatment-to-target strategy.

Horton SC, Tan AL, Freeston JE, Wakefield RJ, Buch MH, Emery P.

Rheumatology (Oxford). 2016 Jul;55(7):1177-87. doi: 10.1093/rheumatology/kew037. Epub 2016 Mar 19.


Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis.

Quarato G, Guy CS, Grace CR, Llambi F, Nourse A, Rodriguez DA, Wakefield R, Frase S, Moldoveanu T, Green DR.

Mol Cell. 2016 Feb 18;61(4):589-601. doi: 10.1016/j.molcel.2016.01.011. Epub 2016 Feb 4.


A prospective, single-centre, randomised study evaluating the clinical, imaging and immunological depth of remission achieved by very early versus delayed Etanercept in patients with Rheumatoid Arthritis (VEDERA).

Dumitru RB, Horton S, Hodgson R, Wakefield RJ, Hensor EMA, Emery P, Buch MH.

BMC Musculoskelet Disord. 2016 Feb 5;17:61. doi: 10.1186/s12891-016-0915-0.


Ultrasound findings predict progression to inflammatory arthritis in anti-CCP antibody-positive patients without clinical synovitis.

Nam JL, Hensor EM, Hunt L, Conaghan PG, Wakefield RJ, Emery P.

Ann Rheum Dis. 2016 Dec;75(12):2060-2067. doi: 10.1136/annrheumdis-2015-208235. Epub 2016 Jan 22.


Summary Findings of a Systematic Literature Review of the Ultrasound Assessment of Bone Erosions in Rheumatoid Arthritis.

Szkudlarek M, Terslev L, Wakefield RJ, Backhaus M, Balint PV, Bruyn GA, Filippucci E, Gandjbakhch F, Iagnocco A, Mandl P, Möller I, Naredo E, Schmidt WA, d'Agostino MA.

J Rheumatol. 2016 Jan;43(1):12-21. doi: 10.3899/jrheum.141416. Epub 2015 Dec 1. Review. Erratum in: J Rheumatol. 2017 Jan;44(1):130.


Value of ultrasonography as a marker of early response to abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results from the APPRAISE study.

D'Agostino MA, Wakefield RJ, Berner-Hammer H, Vittecoq O, Filippou G, Balint P, Möller I, Iagnocco A, Naredo E, Østergaard M, Boers M, Gaillez C, Van Holder K, Le Bars M; OMERACT-EULAR-Ultrasound Task Force.

Ann Rheum Dis. 2016 Oct;75(10):1763-9. doi: 10.1136/annrheumdis-2015-207709. Epub 2015 Nov 20.


Educational recommendations for the conduct, content and format of EULAR musculoskeletal ultrasound Teaching the Teachers Courses.

Iagnocco A, Terslev L, Backhaus M, Balint P, Bruyn GA, Damjanov N, Filippucci E, Hammer HB, Jousse-Joulin S, Kane D, Koski JM, Mandl P, Möller I, Peetrons P, Schmidt W, Szkudlarek M, Vojinovic J, Wakefield RJ, Hofer M, D'Agostino MA, Naredo E.

RMD Open. 2015 Oct 6;1(1):e000139. doi: 10.1136/rmdopen-2015-000139. eCollection 2015.


Accuracy of musculoskeletal imaging for the diagnosis of polymyalgia rheumatica: systematic review.

Mackie SL, Koduri G, Hill CL, Wakefield RJ, Hutchings A, Loy C, Dasgupta B, Wyatt JC.

RMD Open. 2015 Aug 13;1(1):e000100. doi: 10.1136/rmdopen-2015-000100. eCollection 2015.


The role of ultrasound in assessing musculoskeletal symptoms of systemic lupus erythematosus: a systematic literature review.

Zayat AS, Md Yusof MY, Wakefield RJ, Conaghan PG, Emery P, Vital EM.

Rheumatology (Oxford). 2016 Mar;55(3):485-94. doi: 10.1093/rheumatology/kev343. Epub 2015 Oct 7. Review.


Reply: To PMID 25370843.

Torp-Pedersen S, Christensen R, Ellegaard K, Torp-Pedersen A, Szkudlarek M, D'Agostino MA, Iagnocco A, Naredo E, Balint P, Wakefield RJ, Terslev L, Jensen JA.

Arthritis Rheumatol. 2015 Jun;67(6):1681-3. doi: 10.1002/art.39057. No abstract available.


Ultrasound assessment of response to intra-articular therapy in osteoarthritis of the knee.

Keen HI, Hensor EM, Wakefield RJ, Mease PJ, Bingham CO 3rd, Conaghan PG.

Rheumatology (Oxford). 2015 Aug;54(8):1385-91. doi: 10.1093/rheumatology/keu529. Epub 2015 Feb 16.


Global ultrasound assessment of structural lesions in osteoarthritis: a reliability study by the OMERACT ultrasonography group on scoring cartilage and osteophytes in finger joints.

Hammer HB, Iagnocco A, Mathiessen A, Filippucci E, Gandjbakhch F, Kortekaas MC, Möller I, Naredo E, Wakefield RJ, Aegerter P, D'Agostino MA.

Ann Rheum Dis. 2016 Feb;75(2):402-7. doi: 10.1136/annrheumdis-2014-206289. Epub 2014 Dec 17.


Oral disease-modifying therapies for relapsing-remitting multiple sclerosis.

Thomas RH, Wakefield RA.

Am J Health Syst Pharm. 2015 Jan 1;72(1):25-38. doi: 10.2146/ajhp140023. Review.


Power and color Doppler ultrasound settings for inflammatory flow: impact on scoring of disease activity in patients with rheumatoid arthritis.

Torp-Pedersen S, Christensen R, Szkudlarek M, Ellegaard K, D'Agostino MA, Iagnocco A, Naredo E, Balint P, Wakefield RJ, Torp-Pedersen A, Terslev L.

Arthritis Rheumatol. 2015 Feb;67(2):386-95. doi: 10.1002/art.38940.


Optimising ultrasonography in rheumatology.

Keen HI, Wakefield R, Conaghan PG.

Clin Exp Rheumatol. 2014 Sep-Oct;32(5 Suppl 85):S-13-6. Epub 2014 Oct 30. Review.


Musculoskeletal ultrasound in rheumatology in Korea: targeted ultrasound initiative survey.

Kang T, Wakefield RJ, Emery P.

Int J Rheum Dis. 2016 Apr;19(4):335-42. doi: 10.1111/1756-185X.12508. Epub 2014 Oct 28.


Skin imaging in systemic sclerosis.

Kang T, Abignano G, Lettieri G, Wakefield RJ, Emery P, Del Galdo F.

Eur J Rheumatol. 2014 Sep;1(3):111-116. Epub 2014 Sep 1. Review.

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