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Items: 1 to 50 of 197

1.

In Vivo Lineage Tracing of Polyploid Hepatocytes Reveals Extensive Proliferation during Liver Regeneration.

Matsumoto T, Wakefield L, Tarlow BD, Grompe M.

Cell Stem Cell. 2020 Jan 2;26(1):34-47.e3. doi: 10.1016/j.stem.2019.11.014. Epub 2019 Dec 19.

PMID:
31866222
2.

SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.

He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23534-23541. doi: 10.1073/pnas.1902308116. Epub 2019 Oct 7.

PMID:
31591207
3.

The Outcome of TGFβ Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFβ.

Yang Y, Yang HH, Tang B, Wu AML, Flanders KC, Moshkovich N, Weinberg DS, Welsh MA, Weng J, Ochoa HJ, Hu TY, Herrmann MA, Chen J, Edmondson EF, Simpson RM, Liu F, Liu H, Lee MP, Wakefield LM.

Clin Cancer Res. 2019 Oct 3. doi: 10.1158/1078-0432.CCR-19-2370. [Epub ahead of print]

PMID:
31582516
4.

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein.

Byun JS, Park S, Yi DI, Shin JH, Hernandez SG, Hewitt SM, Nicklaus MC, Peach ML, Guasch L, Tang B, Wakefield LM, Yan T, Caban A, Jones A, Kabbout M, Vohra N, Nápoles AM, Singhal S, Yancey R, De Siervi A, Gardner K.

Cell Death Dis. 2019 Sep 18;10(10):689. doi: 10.1038/s41419-019-1892-7.

5.

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription.

Malik N, Yan H, Moshkovich N, Palangat M, Yang H, Sanchez V, Cai Z, Peat TJ, Jiang S, Liu C, Lee M, Mock BA, Yuspa SH, Larson D, Wakefield LM, Huang J.

Nat Commun. 2019 May 6;10(1):2071. doi: 10.1038/s41467-019-10102-6.

6.

Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure.

Torres S, Baulies A, Insausti-Urkia N, Alarcón-Vila C, Fucho R, Solsona-Vilarrasa E, Núñez S, Robles D, Ribas V, Wakefield L, Grompe M, Lucena MI, Andrade RJ, Win S, Aung TA, Kaplowitz N, García-Ruiz C, Fernández-Checa JC.

Gastroenterology. 2019 Aug;157(2):552-568. doi: 10.1053/j.gastro.2019.04.023. Epub 2019 Apr 25.

7.

Identification and Isolation of Clonogenic Cholangiocyte in Mouse.

Li B, Dorrell C, Canady PS, Wakefield L.

Methods Mol Biol. 2019;1905:19-27. doi: 10.1007/978-1-4939-8961-4_3.

PMID:
30536087
8.

HLA-B*45:22: a novel allele that differs from HLA-B*45:01:01 at several locations.

Dukek BA, Zuccarelli MD, Wakefield LL, Kreuter JD, Gandhi MJ.

HLA. 2019 Jan;93(1):49-50. doi: 10.1111/tan.13422. Epub 2018 Dec 6.

PMID:
30421561
9.

The association of de novo anti-HLA-DPB1 donor-specific antibody formation and primary graft failure after allogeneic hematopoietic cell transplantation.

Hefazi M, Hogan WJ, Wakefield LL, Gandhi MJ.

Hum Immunol. 2018 Dec;79(12):861-864. doi: 10.1016/j.humimm.2018.08.009. Epub 2018 Aug 22.

PMID:
30142360
10.

Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target.

Brooks D, Zimmer A, Wakefield L, Lyle LT, Difilippantonio S, Tucci FC, Illiano S, Annunziata CM, Steeg PS.

Oncotarget. 2018 May 4;9(34):23462-23481. doi: 10.18632/oncotarget.25231. eCollection 2018 May 4.

11.

Identifying a newly discovered HLA-C allele: HLA-C*07:607.

Duellman PM, Schneider BA, Dukek BA, Wakefield LL, Gandhi MJ.

HLA. 2018 May 7. doi: 10.1111/tan.13290. [Epub ahead of print]

PMID:
29732717
12.

Does matching for SNPs in the MHC gamma block in 10/10 HLA-matched unrelated donor-recipient pairs undergoing allogeneic stem cell transplant improve outcomes?

Moyer AM, Hashmi SK, Kroning C, De Goey SR, Patnaik M, Litzow M, Gastineau DA, Hogan WJ, Jacob EK, Kreuter JD, Wakefield LL, Gandhi MJ.

Hum Immunol. 2018 Jul;79(7):532-536. doi: 10.1016/j.humimm.2018.04.008. Epub 2018 Apr 13.

PMID:
29660451
13.

Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts.

Wang Y, Dorrell C, Naugler WE, Heskett M, Spellman P, Li B, Galivo F, Haft A, Wakefield L, Grompe M.

Mol Ther. 2018 May 2;26(5):1327-1342. doi: 10.1016/j.ymthe.2018.02.014. Epub 2018 Feb 21.

14.

Genetic insights into the morass of metastatic heterogeneity.

Hunter KW, Amin R, Deasy S, Ha NH, Wakefield L.

Nat Rev Cancer. 2018 Apr;18(4):211-223. doi: 10.1038/nrc.2017.126. Epub 2018 Feb 9. Review.

15.

Comparison Between Total IgG, C1q, and C3d Single Antigen Bead Assays in Detecting Class I Complement-Binding Anti-HLA Antibodies.

Moreno Gonzales MA, Mitema DG, Smith BH, Schinstock CA, Stegall MD, Wakefield LL, Henderson NA, DeGoey SR, Kreuter JD, Gandhi MJ.

Transplant Proc. 2017 Nov;49(9):2031-2035. doi: 10.1016/j.transproceed.2017.09.040.

PMID:
29149956
16.

How do I … manage the platelet transfusion-refractory patient?

Juskewitch JE, Norgan AP, De Goey SR, Duellman PM, Wakefield LL, Gandhi MJ, Stubbs JR, Kreuter JD.

Transfusion. 2017 Dec;57(12):2828-2835. doi: 10.1111/trf.14316. Epub 2017 Sep 28.

PMID:
28960321
17.

Clinical outcomes of HLA-DPB1 mismatches in 10/10 HLA-matched unrelated donor-recipient pairs undergoing allogeneic stem cell transplant.

Moyer AM, Hashmi SK, Kroning CM, Kremers WK, De Goey SR, Patnaik M, Litzow M, Gastineau DA, Hogan WJ, Jacob EK, Kreuter JD, Wakefield LL, Gandhi MJ.

Eur J Haematol. 2017 Sep;99(3):275-282. doi: 10.1111/ejh.12916. Epub 2017 Jul 21.

PMID:
28632323
18.

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3.

Chaudhary R, Gryder B, Woods WS, Subramanian M, Jones MF, Li XL, Jenkins LM, Shabalina SA, Mo M, Dasso M, Yang Y, Wakefield LM, Zhu Y, Frier SM, Moriarity BS, Prasanth KV, Perez-Pinera P, Lal A.

Elife. 2017 Jun 5;6. pii: e23244. doi: 10.7554/eLife.23244.

19.

Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis.

Yang Y, Yang HH, Hu Y, Watson PH, Liu H, Geiger TR, Anver MR, Haines DC, Martin P, Green JE, Lee MP, Hunter KW, Wakefield LM.

Oncotarget. 2017 May 9;8(19):30621-30643. doi: 10.18632/oncotarget.15695.

20.

The 'HLA conundrum in bone marrow transplantation': correct interpretation of anti-HLA antibodies in haploidentical donor selection.

Dias AL, Hashmi S, Hogan W, Baig N, Wakefield L, Kreuter J, Gandhi MJ.

Bone Marrow Transplant. 2017 Jun;52(6):902-904. doi: 10.1038/bmt.2017.13. Epub 2017 Feb 20. No abstract available.

PMID:
28218752
21.

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium.

Flanders KC, Yang YA, Herrmann M, Chen J, Mendoza N, Mirza AM, Wakefield LM.

Oncotarget. 2016 Jun 21;7(25):38164-38179. doi: 10.18632/oncotarget.9416.

22.

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.

Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A.

J Natl Cancer Inst. 2016 Sep 15;109(1). doi: 10.1093/jnci/djw189. Print 2017 Jan.

23.

Immune-mediated pathology in Duchenne muscular dystrophy.

Rosenberg AS, Puig M, Nagaraju K, Hoffman EP, Villalta SA, Rao VA, Wakefield LM, Woodcock J.

Sci Transl Med. 2015 Aug 5;7(299):299rv4. doi: 10.1126/scitranslmed.aaa7322. Review.

24.

Capillary nano-immunoassays: advancing quantitative proteomics analysis, biomarker assessment, and molecular diagnostics.

Chen JQ, Wakefield LM, Goldstein DJ.

J Transl Med. 2015 Jun 6;13:182. doi: 10.1186/s12967-015-0537-6. Review.

25.

Ten-year Retrospective Study on the Efficacy of a Manual Physical Therapy to Treat Female Infertility.

Rice AD, Patterson K, Wakefield LB, Reed ED, Breder KP, Wurn BF, King Iii R, Wurn LJ.

Altern Ther Health Med. 2015 May-Jun;21(3):36-44.

PMID:
26026143
26.

Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model.

Sato M, Matsubara T, Adachi J, Hashimoto Y, Fukamizu K, Kishida M, Yang YA, Wakefield LM, Tomonaga T.

PLoS One. 2015 May 18;10(5):e0126483. doi: 10.1371/journal.pone.0126483. eCollection 2015.

27.

Growth differentiation factor-15 encodes a novel microRNA 3189 that functions as a potent regulator of cell death.

Jones MF, Li XL, Subramanian M, Shabalina SA, Hara T, Zhu Y, Huang J, Yang Y, Wakefield LM, Prasanth KV, Lal A.

Cell Death Differ. 2015 Oct;22(10):1641-53. doi: 10.1038/cdd.2015.9. Epub 2015 Feb 20.

28.

Ten-year Retrospective Study on the Efficacy of a Manual Physical Therapy to Treat Female Infertility.

Rice AD, Patterson K, Wakefield LB, Reed ED, Breder KP, Wurn BF, King Iii R, Wurn LJ.

Altern Ther Health Med. 2015 Feb 17. pii: at5233. [Epub ahead of print]

PMID:
25691329
29.

A flexible reporter system for direct observation and isolation of cancer stem cells.

Tang B, Raviv A, Esposito D, Flanders KC, Daniel C, Nghiem BT, Garfield S, Lim L, Mannan P, Robles AI, Smith WI Jr, Zimmerberg J, Ravin R, Wakefield LM.

Stem Cell Reports. 2015 Jan 13;4(1):155-169. doi: 10.1016/j.stemcr.2014.11.002. Epub 2014 Dec 11.

30.

Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes.

Tarlow BD, Pelz C, Naugler WE, Wakefield L, Wilson EM, Finegold MJ, Grompe M.

Cell Stem Cell. 2014 Nov 6;15(5):605-18. doi: 10.1016/j.stem.2014.09.008. Epub 2014 Oct 9.

31.

Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cells.

Hara T, Jones MF, Subramanian M, Li XL, Ou O, Zhu Y, Yang Y, Wakefield LM, Hussain SP, Gaedcke J, Ried T, Luo J, Caplen NJ, Lal A.

Oncotarget. 2014 Sep 15;5(17):7635-50.

32.

Definition of smad3 phosphorylation events that affect malignant and metastatic behaviors in breast cancer cells.

Bae E, Sato M, Kim RJ, Kwak MK, Naka K, Gim J, Kadota M, Tang B, Flanders KC, Kim TA, Leem SH, Park T, Liu F, Wakefield LM, Kim SJ, Ooshima A.

Cancer Res. 2014 Nov 1;74(21):6139-49. doi: 10.1158/0008-5472.CAN-14-0803. Epub 2014 Sep 9.

33.

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

Flanders KC, Heger CD, Conway C, Tang B, Sato M, Dengler SL, Goldsmith PK, Hewitt SM, Wakefield LM.

J Histochem Cytochem. 2014 Dec;62(12):846-63. doi: 10.1369/0022155414550163. Epub 2014 Aug 20.

34.

Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide.

Chen X, Wakefield LM, Oppenheim JJ.

Oncoimmunology. 2014 Apr 16;3:e28247. eCollection 2014.

35.

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer.

Sato M, Kadota M, Tang B, Yang HH, Yang YA, Shan M, Weng J, Welsh MA, Flanders KC, Nagano Y, Michalowski AM, Clifford RJ, Lee MP, Wakefield LM.

Breast Cancer Res. 2014 Jun 2;16(3):R57. doi: 10.1186/bcr3668.

36.

Decreasing adhesions and avoiding further surgery in a pediatric patient involved in a severe pedestrian versus motor vehicle accident.

Rice AD, Wakefield LB, Patterson K, Reed ED, Wurn BF, King CR 3rd, Wurn LJ.

Pediatr Rep. 2014 Feb 24;6(1):5126. doi: 10.4081/pr.2014.5126. eCollection 2014 Feb 17.

37.

A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.

Subramanian M, Francis P, Bilke S, Li XL, Hara T, Lu X, Jones MF, Walker RL, Zhu Y, Pineda M, Lee C, Varanasi L, Yang Y, Martinez LA, Luo J, Ambs S, Sharma S, Wakefield LM, Meltzer PS, Lal A.

Oncogene. 2015 Feb 26;34(9):1094-104. doi: 10.1038/onc.2014.46. Epub 2014 Mar 24.

38.

Pillars Article: production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J Exp Med. 1986. 163: 1037-1050.

Kehrl JH, Wakefield LM, Roberts AB, Jakowlew S, Alvarez-Mon M, Derynck R, Sporn MB, Fauci AS.

J Immunol. 2014 Apr 1;192(7):2939-52. No abstract available.

39.

Nicotine exposure during differentiation causes inhibition of N-myc expression.

Ben-Yehudah A, Campanaro BM, Wakefield LM, Kinney TN, Brekosky J, Eisinger VM, Castro CA, Carlisle DL.

Respir Res. 2013 Nov 5;14:119. doi: 10.1186/1465-9921-14-119.

40.

Effective chemoimmunotherapy with anti-TGFβ antibody and cyclophosphamide in a mouse model of breast cancer.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, McPherson JM, Wakefield LM, Oppenheim JJ.

PLoS One. 2014 Jan 9;9(1):e85398. doi: 10.1371/journal.pone.0085398. eCollection 2014.

41.

Development and Validation of a Questionnaire to Measure Serious and Common Quality of Life Issues for Patients Experiencing Small Bowel Obstructions.

Rice AD, Wakefield LB, Patterson K, D'Avy Reed E, Wurn BF, Klingenberg B, King Iii CR, Wurn LJ.

Healthcare (Basel). 2014 Mar 7;2(1):139-49. doi: 10.3390/healthcare2010139.

42.

A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster.

Li XL, Hara T, Choi Y, Subramanian M, Francis P, Bilke S, Walker RL, Pineda M, Zhu Y, Yang Y, Luo J, Wakefield LM, Brabletz T, Park BH, Sharma S, Chowdhury D, Meltzer PS, Lal A.

Mol Cell Biol. 2014 Feb;34(3):533-50. doi: 10.1128/MCB.01043-13. Epub 2013 Nov 25.

43.

Expression of the B-cell receptor component CD79a on immature myeloid cells contributes to their tumor promoting effects.

Luger D, Yang YA, Raviv A, Weinberg D, Banerjee S, Lee MJ, Trepel J, Yang L, Wakefield LM.

PLoS One. 2013 Oct 16;8(10):e76115. doi: 10.1371/journal.pone.0076115. eCollection 2013.

44.

Genetic background may contribute to PAM50 gene expression breast cancer subtype assignments.

Hu Y, Bai L, Geiger T, Goldberger N, Walker RC, Green JE, Wakefield LM, Hunter KW.

PLoS One. 2013 Aug 28;8(8):e72287. doi: 10.1371/journal.pone.0072287. eCollection 2013.

45.

Beyond TGFβ: roles of other TGFβ superfamily members in cancer.

Wakefield LM, Hill CS.

Nat Rev Cancer. 2013 May;13(5):328-41. doi: 10.1038/nrc3500. Review.

PMID:
23612460
46.

SDF-1α mediates wound-promoted tumor growth in a syngeneic orthotopic mouse model of breast cancer.

Stuelten CH, Cervoni-Curet FN, Busch JI, Sutton E, Webster JD, Kavalukas SL, Wakefield LM, Barbul A, Niederhuber JE.

PLoS One. 2013 Apr 11;8(4):e60919. doi: 10.1371/journal.pone.0060919. Print 2013.

47.

Investigating silver coordination to mixed chalcogen ligands.

Knight FR, Randall RA, Wakefield L, Slawin AM, Woollins JD.

Molecules. 2012 Nov 8;17(11):13307-29. doi: 10.3390/molecules171113307.

48.

Silver(I) coordination complexes and extended networks assembled from S, Se, Te substituted acenaphthenes.

Knight FR, Randall RA, Wakefield L, Slawin AM, Woollins JD.

Dalton Trans. 2013 Jan 7;42(1):143-54. doi: 10.1039/c2dt31390a.

PMID:
23108191
49.

TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury.

Matsubara T, Tanaka N, Sato M, Kang DW, Krausz KW, Flanders KC, Ikeda K, Luecke H, Wakefield LM, Gonzalez FJ.

J Lipid Res. 2012 Dec;53(12):2698-707. doi: 10.1194/jlr.M031773. Epub 2012 Oct 3.

50.

Noncovalent interactions in peri-substituted chalconium acenaphthene and naphthalene salts: a combined experimental, crystallographic, computational, and solid-state NMR study.

Knight FR, Randall RA, Athukorala Arachchige KS, Wakefield L, Griffin JM, Ashbrook SE, Bühl M, Slawin AM, Woollins JD.

Inorg Chem. 2012 Oct 15;51(20):11087-97. doi: 10.1021/ic301627y. Epub 2012 Sep 24.

PMID:
23004571

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