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Items: 1 to 50 of 97

1.

Structure-Based Analysis of Cryptic-Site Opening.

Sun Z, Wakefield AE, Kolossvary I, Beglov D, Vajda S.

Structure. 2020 Feb 4;28(2):223-235.e2. doi: 10.1016/j.str.2019.11.007. Epub 2019 Dec 3.

PMID:
31810712
2.

Analysis of tractable allosteric sites in G protein-coupled receptors.

Wakefield AE, Mason JS, Vajda S, Keserű GM.

Sci Rep. 2019 Apr 16;9(1):6180. doi: 10.1038/s41598-019-42618-8.

3.

Cryptic binding sites on proteins: definition, detection, and druggability.

Vajda S, Beglov D, Wakefield AE, Egbert M, Whitty A.

Curr Opin Chem Biol. 2018 Jun;44:1-8. doi: 10.1016/j.cbpa.2018.05.003. Epub 2018 May 23. Review.

4.

Exploring the structural origins of cryptic sites on proteins.

Beglov D, Hall DR, Wakefield AE, Luo L, Allen KN, Kozakov D, Whitty A, Vajda S.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3416-E3425. doi: 10.1073/pnas.1711490115. Epub 2018 Mar 26.

5.

Molecular Simulation of Conformational Pre-Organization in Cyclic RGD Peptides.

Wakefield AE, Wuest WM, Voelz VA.

J Chem Inf Model. 2015 Apr 27;55(4):806-13. doi: 10.1021/ci500768u. Epub 2015 Mar 20.

PMID:
25741627
6.

Biomechanics of thoracic discectomy.

Wakefield AE, Steinmetz MP, Benzel EC.

Neurosurg Focus. 2001 Sep 15;11(3):E6.

PMID:
16519426
7.

Genotypic variation in Pneumocystis jirovecii isolates in Britain.

Miller RF, Lindley AR, Copas A, Ambrose HE, Davies RJ, Wakefield AE.

Thorax. 2005 Aug;60(8):679-82.

8.

Gene arrays at Pneumocystis carinii telomeres.

Keely SP, Renauld H, Wakefield AE, Cushion MT, Smulian AG, Fosker N, Fraser A, Harris D, Murphy L, Price C, Quail MA, Seeger K, Sharp S, Tindal CJ, Warren T, Zuiderwijk E, Barrell BG, Stringer JR, Hall N.

Genetics. 2005 Aug;170(4):1589-600. Epub 2005 Jun 18.

9.

Isolates of Pneumocystis jirovecii from Harare show high genotypic similarity to isolates from London at the superoxide dismutase locus.

Miller RF, Lindley AR, Malin AS, Ambrose HE, Wakefield AE.

Trans R Soc Trop Med Hyg. 2005 Mar;99(3):202-6.

PMID:
15653122
10.

Estimating the risk of nonunion following nonoperative treatment of a clavicular fracture.

Robinson CM, Court-Brown CM, McQueen MM, Wakefield AE.

J Bone Joint Surg Am. 2004 Jul;86(7):1359-65.

PMID:
15252081
11.

Expression and complexity of the PRT1 multigene family of Pneumocystis carinii.

Ambrose HE, Keely SP, Aliouat EM, Dei-Cas E, Wakefield AE, Miller RF, Stringer JR.

Microbiology. 2004 Feb;150(Pt 2):293-300. doi: 10.1099/mic.0.26539-0.

PMID:
14766907
12.

Multilocus genotyping of Pneumocystis jirovecii from adult HIV-infected patients with Pneumocystis pneumonia.

Miller RF, Lindley AR, Ambrose HE, Aliouat-Denis CM, Wakefield AE.

J Eukaryot Microbiol. 2003;50 Suppl:654-5. No abstract available.

PMID:
14736205
13.

Genotypes of Pneumocystis jiroveci isolates obtained in Harare, Zimbabwe, and London, United Kingdom.

Miller RF, Lindley AR, Ambrose HE, Malin AS, Wakefield AE.

Antimicrob Agents Chemother. 2003 Dec;47(12):3979-81.

14.

Assessment of Pneumocystis species carriage in captive primates.

Demanche C, Petit T, Moisson P, Ollivet F, Rigoulet J, Chermette R, Dei-Cas E, Wakefield AE, Guillot J.

Vet Rec. 2003 Jun 28;152(26):811-3. No abstract available.

PMID:
12862172
15.

Primary hemiarthroplasty for treatment of proximal humeral fractures.

Robinson CM, Page RS, Hill RM, Sanders DL, Court-Brown CM, Wakefield AE.

J Bone Joint Surg Am. 2003 Jul;85(7):1215-23.

PMID:
12851345
16.

Asymptomatic carriage of Pneumocystis jiroveci in subjects undergoing bronchoscopy: a prospective study.

Maskell NA, Waine DJ, Lindley A, Pepperell JC, Wakefield AE, Miller RF, Davies RJ.

Thorax. 2003 Jul;58(7):594-7.

17.

Limited asymptomatic carriage of Pneumocystis jiroveci in human immunodeficiency virus-infected patients.

Wakefield AE, Lindley AR, Ambrose HE, Denis CM, Miller RF.

J Infect Dis. 2003 Mar 15;187(6):901-8. Epub 2003 Mar 6.

PMID:
12660936
18.

Pneumocystis carinii pneumonia with pleurisy, platypnoea and orthodeoxia.

Newton PN, Wakefield AE, Goldin R, Govan J.

Thorax. 2003 Feb;58(2):185-6.

19.
20.

A new name (Pneumocystis jiroveci) for Pneumocystis from humans.

Stringer JR, Beard CB, Miller RF, Wakefield AE.

Emerg Infect Dis. 2002 Sep;8(9):891-6. Review.

21.

Absence of mutations associated with sulfa resistance in Pneumocystis carinii dihydropteroate synthase gene from non-human primates.

Demanche C, Guillot J, Berthelemy M, Petitt T, Roux P, Wakefield AE.

Med Mycol. 2002 Jun;40(3):315-8.

PMID:
12146763
22.

Pneumocystis carinii.

Wakefield AE.

Br Med Bull. 2002;61:175-88. Review.

PMID:
11997305
23.

Probable mother-to-infant transmission of Pneumocystis carinii f. sp. hominis infection.

Miller RF, Ambrose HE, Novelli V, Wakefield AE.

J Clin Microbiol. 2002 Apr;40(4):1555-7.

24.

New nomenclature for the genus Pneumocystis.

Stringer JR, Cushion MT, Wakefield AE.

J Eukaryot Microbiol. 2001;Suppl:184S-189S. Review. No abstract available.

PMID:
11906056
25.

Detailed structure of Pneumocystis carinii chromosome ends.

Keely SP, Wakefield AE, Cushion MT, Smulian AG, Hall N, Barrell BG, Stringer JR.

J Eukaryot Microbiol. 2001;Suppl:118S-120S. No abstract available.

PMID:
11906018
26.

Parallel phylogenies of Pneumocystis species and their mammalian hosts.

Guillot J, Demanche C, Hugot JP, Berthelemy M, Wakefield AE, Dei-Cas E, Chermette R.

J Eukaryot Microbiol. 2001;Suppl:113S-115S.

PMID:
11906016
27.

Functional glycosylphosphatidylinositol anchor signal sequences in the Pneumocystis carinii PRT1 protease family.

Palmer RJ, Wakefield AE.

Am J Respir Cell Mol Biol. 2001 Oct;25(4):466-73.

PMID:
11694452
28.
29.

Distribution of Pneumocystis carinii f. sp. hominis types in the lung of a child dying of Pneumocystis pneumonia.

Ambrose HE, Ponce CA, Wakefield AE, Miller RF, Vargas SL.

Clin Infect Dis. 2001 Nov 1;33(9):e100-2. Epub 2001 Sep 24.

PMID:
11568852
30.

Phylogeny of Pneumocystis carinii from 18 primate species confirms host specificity and suggests coevolution.

Demanche C, Berthelemy M, Petit T, Polack B, Wakefield AE, Dei-Cas E, Guillot J.

J Clin Microbiol. 2001 Jun;39(6):2126-33.

31.

Determination of the copy number of the nuclear rDNA and beta-tubulin genes of Pneumocystis carinii f. sp. hominis using PCR multicompetitors.

Nahimana A, Francioli P, Blanc DS, Bille J, Wakefield AE, Hauser PM.

J Eukaryot Microbiol. 2000 Jul-Aug;47(4):368-72.

PMID:
11140450
32.

Transmission of Pneumocystis carinii disease from immunocompetent contacts of infected hosts to susceptible hosts.

Dumoulin A, Mazars E, Seguy N, Gargallo-Viola D, Vargas S, Cailliez JC, Aliouat EM, Wakefield AE, Dei-Cas E.

Eur J Clin Microbiol Infect Dis. 2000 Sep;19(9):671-8.

PMID:
11057500
33.

Population structure of rat-derived Pneumocystis carinii in Danish wild rats.

Palmer RJ, Settnes OP, Lodal J, Wakefield AE.

Appl Environ Microbiol. 2000 Nov;66(11):4954-61.

34.

The role of physiotherapy and clinical predictors of outcome after fracture of the distal radius.

Wakefield AE, McQueen MM.

J Bone Joint Surg Br. 2000 Sep;82(7):972-6.

PMID:
11041584
35.

Genetic divergence at the SODA locus of six different formae speciales of Pneumocystis carinii.

Denis CM, Mazars E, Guyot K, Odberg-Ferragut C, Viscogliosi E, Dei-Cas E, Wakefield AE.

Med Mycol. 2000 Aug;38(4):289-300.

PMID:
10975697
36.

Ultrastructural and molecular characterization of Pneumocystis carinii isolated from a rhesus monkey (Macaca mulatta).

Durand-Joly I, Wakefield AE, Palmer RJ, Denis CM, Creusy C, Fleurisse L, Ricard I, Gut JP, Dei-Cas E.

Med Mycol. 2000 Feb;38(1):61-72.

PMID:
10746229
37.

Pneumocystis carinii infection in young non-immunosuppressed rabbits. Kinetics of infection and of the primary specific immune response.

Tamburrini E, Ortona E, Visconti E, Mencarini P, Margutti P, Zolfo M, Barca S, Peters SE, Wakefield AE, Siracusano A.

Med Microbiol Immunol. 1999 Aug;188(1):1-7.

PMID:
10691087
38.

Association of primary Pneumocystis carinii infection and sudden infant death syndrome.

Vargas SL, Ponce CA, Hughes WT, Wakefield AE, Weitz JC, Donoso S, Ulloa AV, Madrid P, Gould S, Latorre JJ, Avila R, Benveniste S, Gallo M, Belletti J, Lopez R.

Clin Infect Dis. 1999 Dec;29(6):1489-93.

PMID:
10585801
39.

Oropharyngeal samples for genotyping and monitoring response to treatment in AIDS patients with Pneumocystis carinii pneumonia.

Tsolaki AG, Miller RF, Wakefield AE.

J Med Microbiol. 1999 Oct;48(10):897-905. doi: 10.1099/00222615-48-10-897.

PMID:
10510966
40.

Pneumocystis carinii genotypes and severity of pneumonia.

Miller RF, Wakefield AE.

Lancet. 1999 Jun 12;353(9169):2039-40. No abstract available.

PMID:
10376625
41.

The affinity of lipid-coated microbubbles to maturing spinal cord injury sites.

Kureshi IU, Ho SY, Onyiuke HC, Wakefield AE, Kureshi IU, D'Arrigo JS, Simon RH.

Neurosurgery. 1999 May;44(5):1047-53.

PMID:
10232538
42.

Cell surface protease PRT1 identified in the fungal pathogen Pneumocystis carinii.

Lugli EB, Bampton ET, Ferguson DJ, Wakefield AE.

Mol Microbiol. 1999 Mar;31(6):1723-33.

43.
44.

Clusters of Pneumocystis carinii pneumonia: analysis of person-to-person transmission by genotyping.

Helweg-Larsen J, Tsolaki AG, Miller RF, Lundgren B, Wakefield AE.

QJM. 1998 Dec;91(12):813-20.

PMID:
10024946
45.

Genetics, metabolism and host specificity of Pneumocystis carinii.

Wakefield AE, Stringer JR, Tamburrini E, Dei-Cas E.

Med Mycol. 1998;36 Suppl 1:183-93. Review.

PMID:
9988507
46.

Sequence polymorphisms in the Pneumocystis carinii cytochrome b gene and their association with atovaquone prophylaxis failure.

Walker DJ, Wakefield AE, Dohn MN, Miller RF, Baughman RP, Hossler PA, Bartlett MS, Smith JW, Kazanjian P, Meshnick SR.

J Infect Dis. 1998 Dec;178(6):1767-75.

PMID:
9815231
47.

PCR for detecting Pneumocystis carinii in clinical or environmental samples.

Lundgren B, Wakefield AE.

FEMS Immunol Med Microbiol. 1998 Sep;22(1-2):97-101.

48.

Genetic heterogeneity in human-derived Pneumocystis carinii.

Wakefield AE.

FEMS Immunol Med Microbiol. 1998 Sep;22(1-2):59-65.

49.

Genetic heterogeneity in Pneumocystis carinii: an introduction.

Wakefield AE.

FEMS Immunol Med Microbiol. 1998 Sep;22(1-2):5-13.

50.

Molecular cloning and characterization of a superoxide dismutase (sod) gene in Pneumocystis carinii.

Denis CM, Guyot K, Wakefield AE, Dive D, Dei-Cas E, Camus D, Odberg-Ferragut C.

J Eukaryot Microbiol. 1998 Sep-Oct;45(5):475-83.

PMID:
9783449

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