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Items: 1 to 50 of 227

1.

DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling.

Ishiguro K, Kitajima H, Niinuma T, Ishida T, Maruyama R, Ikeda H, Hayashi T, Sasaki H, Wakasugi H, Nishiyama K, Shindo T, Yamamoto E, Kai M, Sasaki Y, Tokino T, Nakase H, Suzuki H.

Haematologica. 2019 Jan;104(1):155-165. doi: 10.3324/haematol.2018.191262. Epub 2018 Aug 31.

2.

Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment.

Wakasugi H, Takahashi H, Niinuma T, Kitajima H, Oikawa R, Matsumoto N, Takeba Y, Otsubo T, Takagi M, Ariizumi Y, Suzuki M, Okuse C, Iwabuchi S, Nakano M, Akutsu N, Kang JH, Matsui T, Yamada N, Sasaki H, Yamamoto E, Kai M, Sasaki Y, Sasaki S, Tanaka Y, Yotsuyanagi H, Tsutsumi T, Yamamoto H, Tokino T, Nakase H, Suzuki H, Itoh F.

Cancer Lett. 2018 Oct 10;434:91-100. doi: 10.1016/j.canlet.2018.07.019. Epub 2018 Jul 17.

PMID:
30026054
3.

Development of hypertension within 2 weeks of initiation of sorafenib for advanced hepatocellular carcinoma is a predictor of efficacy.

Akutsu N, Sasaki S, Takagi H, Motoya M, Shitani M, Igarashi M, Hirayama D, Wakasugi H, Yamamoto H, Kaneto H, Yonezawa K, Yawata A, Adachi T, Hamamoto Y, Shinomura Y.

Int J Clin Oncol. 2015 Feb;20(1):105-10. doi: 10.1007/s10147-014-0691-5. Epub 2014 Apr 18.

PMID:
24744262
4.

[A case of recurrent gastric cancer showing partial response to capecitabine/CDDP after treatment with S-1/CDDP].

Goto A, Itoh M, Wakasugi H, Kanno S, Yabana T, Mitsuhashi K, Adachi T, Kondo Y, Suzuki T, Shinomura Y.

Gan To Kagaku Ryoho. 2012 Oct;39(10):1563-6. Japanese.

PMID:
23064073
5.

Low-density lipoprotein apheresis therapy for steroid- and cyclosporine-resistant idiopathic membranous nephropathy.

Sato Y, Tsunoda S, Nozue T, Pan Q, Wakasugi H, Yoshimura A.

Intern Med. 2012;51(18):2597-602. Epub 2012 Sep 15.

6.

Intestinal immune-potentiation by a purified alkylglycerols compound.

Kantah MK, Wakasugi H, Kumari A, Carrera-Bastos P, Palmieri B, Naito Y, Catanzaro R, Kobayashi R, Marotta F.

Acta Biomed. 2012 Apr;83(1):36-43.

PMID:
22978056
7.

Extensive portal and mesenteric vein thrombosis in a young man with Klinefelter's syndrome.

Matsunaga Y, Goto A, Wakasugi H, Itoh A, Yonezawa K, Itoh M, Fujii K, Suzuki K, Abe T, Ushijima K, Shinomura Y.

Hepatol Res. 2012 Jan;42(1):103-9. doi: 10.1111/j.1872-034X.2011.00903.x.

PMID:
22175800
8.

Efficient and substrate-specific hydration of nitriles to amides in water by using a CeO2 catalyst.

Tamura M, Wakasugi H, Shimizu K, Satsuma A.

Chemistry. 2011 Oct 4;17(41):11428-31. doi: 10.1002/chem.201101576. Epub 2011 Aug 29. No abstract available.

PMID:
21953923
9.

Irinotecan as the key chemotherapeutic agent in second-line treatment of metastatic gastric cancer after failure of first-line S-1 or S-1/CDDP therapy.

Goto A, Sukawa Y, Igarashi H, Onodera K, Aoki Y, Suzuki K, Yonezawa K, Yawata A, Kobayashi T, Kaneto H, Shimizu H, Wakasugi H, Matsunaga Y, Itoh M, Okuda H, Arimura Y, Shinomura Y.

Gan To Kagaku Ryoho. 2011 Sep;38(9):1461-6.

PMID:
21945893
10.

Pancreatic-colonic fistula successfully treated with endoscopic transpapillary nasopancreatic drainage.

Fujii K, Suzuki K, Goto A, Nakahata K, Matsunaga Y, Wakasugi H, Itoh M, Yonezawa K, Abe T, Shinomura Y.

Endoscopy. 2011;43 Suppl 2 UCTN:E154-5. doi: 10.1055/s-0030-1256259. Epub 2011 May 11. No abstract available.

PMID:
21563059
11.

[A case of hepatocellular carcinoma diagnosed based on the result of a bone biopsy, in which the primary hepatocellular carcinoma was identified in the liver 14 months after the initial diagnosis].

Kubo T, Akutsu N, Wakasugi H, Shitani M, Ohashi H, Kashiwaya K, Hosokawa M, Takagi H, Yamamoto H, Sasaki S, Mizuguchi T, Hirata K, Hasegawa T, Shinomura Y.

Nihon Shokakibyo Gakkai Zasshi. 2011 May;108(5):805-12. Review. Japanese.

PMID:
21558749
12.

Gastric rupture before puncture of the stomach in percutaneous gastrostomy.

Matsunaga Y, Goto A, Kaneko H, Hasegawa N, Wakasugi H, Itoh M, Fujii K, Suzuki K, Nakahata K, Shinomura Y.

Endoscopy. 2011;43 Suppl 2 UCTN:E57. doi: 10.1055/s-0030-1256077. Epub 2011 Feb 1. No abstract available.

PMID:
21287452
13.

Desquamative esophagitis due to pemphigus vulgaris.

Matunaga Y, Goto A, Fujii K, Nakamura H, Itoh M, Wakasugi H, Suzuki K, Yonezawa K, Abe T, Shinomura Y.

Endoscopy. 2010;42 Suppl 2:E285. doi: 10.1055/s-0030-1255569. Epub 2010 Nov 17. No abstract available. Erratum in: Endoscopy. 2010;42 Suppl 2:E322.

PMID:
21086254
14.

[Effectiveness and safety of chemoradiation in a community-based population of patients with esophageal cancer].

Goto A, Hasegawa Y, Sukawa Y, Fujii K, Matunaga Y, Suzuki K, Yonezawa K, Abe T, Wakasugi H, Itoh M, Itoh A, Shinomura Y, Kagei K.

Gan To Kagaku Ryoho. 2010 Nov;37(11):2115-9. Japanese.

PMID:
21084810
15.

Anorectal melanoma with a KIT-activating mutation, which is a target for tyrosine kinase inhibitor.

Itoh M, Goto A, Wakasugi H, Yoshida Y, Matsunaga Y, Fujii K, Suzuki K, Yonezawa K, Abe T, Arimura Y, Shinomura Y.

Int J Clin Oncol. 2011 Aug;16(4):428-34. doi: 10.1007/s10147-010-0139-5. Epub 2010 Nov 11.

PMID:
21069551
16.

Regurgitation of a mass into the mouth: a fibrovascular polyp of the esophagus.

Goto A, Suzuki M, Iizuka K, Yoshida Y, Suzuki K, Itoh M, Wakasugi H, Fujii K, Matunaga Y, Shinomura Y.

Endoscopy. 2010;42 Suppl 2:E248-9. doi: 10.1055/s-0030-1255618. Epub 2010 Oct 7. No abstract available.

PMID:
20931465
17.

A case of IgG4-positive multiorgan lymphoproliferative syndrome: dramatic perturbations of the CD8-positive T-cell repertoire in peripheral blood.

Tsunoda S, Yachie A, Wakasugi H, Matsushita K, Yamaguchi Y, Kawano M.

Scand J Rheumatol. 2010 Nov;39(6):520-3. doi: 10.3109/03009742.2010.486765. Epub 2010 Sep 21. No abstract available.

PMID:
20858140
18.

Reversible choreoathetosis after the administration of ceftriaxone sodium in patients with end-stage renal disease.

Sato Y, Morita H, Wakasugi H, Iijima S, Kawashima E, Wakayama Y, Yoshimura A.

Am J Med Sci. 2010 Nov;340(5):382-4. doi: 10.1097/MAJ.0b013e3181ec063b.

PMID:
20724905
19.

[Hyperplastic hepatic nodules in a case of idiopathic portal hypertension: changes in imaging findings during a 6-year follow-up].

Akutsu N, Wakasugi H, Ohzeki R, Ohashi H, Takagi H, Yamamoto H, Sasaki S, Katsuramaki T, Hirata K, Hasegawa T, Shinomura Y.

Nihon Shokakibyo Gakkai Zasshi. 2010 Jan;107(1):102-11. Japanese.

PMID:
20057189
20.

Surgery versus radiochemotherapy for resectable locally invasive pancreatic cancer: final results of a randomized multi-institutional trial.

Doi R, Imamura M, Hosotani R, Imaizumi T, Hatori T, Takasaki K, Funakoshi A, Wakasugi H, Asano T, Hishinuma S, Ogata Y, Sunamura M, Yamaguchi K, Tanaka M, Takao S, Aikou T, Hirata K, Maguchi H, Aiura K, Aoki T, Kakita A, Sasaki M, Ozaki M, Matsusue S, Higashide S, Noda H, Ikeda S, Maetani S, Yoshida S; Japan Pancreatic Cancer Study Group.

Surg Today. 2008;38(11):1021-8. doi: 10.1007/s00595-007-3745-8. Epub 2008 Oct 29.

PMID:
18958561
21.

Insufficient ex vivo expansion of Valpha24(+) natural killer T cells in malignant lymphoma patients related to the suppressed expression of CD1d molecules on CD14(+) cells.

Imataki O, Heike Y, Makiyama H, Iizuka A, Ikarashi Y, Ishida T, Wakasugi H, Takaue Y.

Cytotherapy. 2008;10(5):497-506. doi: 10.1080/14653240802072747.

PMID:
18608348
22.

Clinical features and prognoses of 23 patients with chronic granulomatous disease followed for 21 years by a single hospital in Japan.

Kobayashi S, Murayama S, Takanashi S, Takahashi K, Miyatsuka S, Fujita T, Ichinohe S, Koike Y, Kohagizawa T, Mori H, Deguchi Y, Higuchi K, Wakasugi H, Sato T, Wada Y, Nagata M, Okabe N, Tatsuzawa O.

Eur J Pediatr. 2008 Dec;167(12):1389-94. doi: 10.1007/s00431-008-0680-7. Epub 2008 Mar 12.

PMID:
18335239
23.

Interleukin (IL)-4 promotes T helper type 2-biased natural killer T (NKT) cell expansion, which is regulated by NKT cell-derived interferon-gamma and IL-4.

Iizuka A, Ikarashi Y, Yoshida M, Heike Y, Takeda K, Quinn G, Wakasugi H, Kitagawa M, Takaue Y.

Immunology. 2008 Jan;123(1):100-7. Epub 2007 Nov 14.

24.

Antiproliferating activity of the mitotic inhibitor pironetin against vindesine- and paclitaxel-resistant human small cell lung cancer H69 cells.

Yoshida M, Matsui Y, Ikarashi Y, Usui T, Osada H, Wakasugi H.

Anticancer Res. 2007 Mar-Apr;27(2):729-36.

25.

Leukoencephalopathy during administration of etanercept for refractory rheumatoid arthritis.

Yamamoto M, Takahashi H, Wakasugi H, Sukawa Y, Saito M, Suzuki C, Naishiro Y, Yamamoto H, Shinomura Y, Imai K.

Mod Rheumatol. 2007;17(1):72-4. Epub 2007 Feb 20.

PMID:
17278027
26.

Modulation of acute graft-versus-host disease and chimerism after adoptive transfer of in vitro-expanded invariant Valpha14 natural killer T cells.

Kuwatani M, Ikarashi Y, Iizuka A, Kawakami C, Quinn G, Heike Y, Yoshida M, Asaka M, Takaue Y, Wakasugi H.

Immunol Lett. 2006 Jul 15;106(1):82-90. Epub 2006 May 23.

PMID:
16806496
27.

Efficient ex vivo expansion of Valpha24+ NKT cells derived from G-CSF-mobilized blood cells.

Imataki O, Heike Y, Ishida T, Takaue Y, Ikarashi Y, Yoshida M, Wakasugi H, Kakizoe T.

J Immunother. 2006 May-Jun;29(3):320-7.

PMID:
16699375
28.
29.

Cell cycle arrest and apoptosis induced by SART-1 gene transduction.

Hosokawa M, Kadota R, Shichijo S, Itoh K, Dmitriev I, Krasnykh V, Curiel DT, Takue Y, Wakasugi H, Takashima S, Heike Y.

Anticancer Res. 2005 May-Jun;25(3B):1983-90.

30.

New plastoquinones isolated from the brown alga, Sargassum micracanthum.

Mori J, Iwashima M, Wakasugi H, Saito H, Matsunaga T, Ogasawara M, Takahashi S, Suzuki H, Hayashi T.

Chem Pharm Bull (Tokyo). 2005 Sep;53(9):1159-63.

31.

Phenotypical and functional alterations during the expansion phase of invariant Valpha14 natural killer T (Valpha14i NKT) cells in mice primed with alpha-galactosylceramide.

Ikarashi Y, Iizuka A, Koshidaka Y, Heike Y, Takaue Y, Yoshida M, Kronenberg M, Wakasugi H.

Immunology. 2005 Sep;116(1):30-7.

32.
33.

Expansion of alpha-galactosylceramide-stimulated Valpha24+ NKT cells cultured in the absence of animal materials.

Harada Y, Imataki O, Heike Y, Kawai H, Shimosaka A, Mori S, Kami M, Tanosaki R, Ikarashi Y, Iizuka A, Yoshida M, Wakasugi H, Saito S, Takaue Y, Takei M, Kakizoe T.

J Immunother. 2005 Jul-Aug;28(4):314-21.

PMID:
16000949
34.

Accelerated chemically induced tumor development mediated by CD4+CD25+ regulatory T cells in wild-type hosts.

Nishikawa H, Kato T, Tawara I, Takemitsu T, Saito K, Wang L, Ikarashi Y, Wakasugi H, Nakayama T, Taniguchi M, Kuribayashi K, Old LJ, Shiku H.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9253-7. Epub 2005 Jun 16.

35.

IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.

Ota T, Takeda K, Akiba H, Hayakawa Y, Ogasawara K, Ikarashi Y, Miyake S, Wakasugi H, Yamamura T, Kronenberg M, Raulet DH, Kinoshita K, Yagita H, Smyth MJ, Okumura K.

Blood. 2005 Jul 1;106(1):184-92. Epub 2005 Mar 3.

36.

ICOS costimulates invariant NKT cell activation.

Kaneda H, Takeda K, Ota T, Kaduka Y, Akiba H, Ikarashi Y, Wakasugi H, Kronenberg M, Kinoshita K, Yagita H, Okumura K.

Biochem Biophys Res Commun. 2005 Feb 4;327(1):201-7.

PMID:
15629449
37.

A randomized multicenter trial comparing resection and radiochemotherapy for resectable locally invasive pancreatic cancer.

Imamura M, Doi R, Imaizumi T, Funakoshi A, Wakasugi H, Sunamura M, Ogata Y, Hishinuma S, Asano T, Aikou T, Hosotani R, Maetani S.

Surgery. 2004 Nov;136(5):1003-11.

PMID:
15523393
38.

Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects.

Borg C, Terme M, Taïeb J, Ménard C, Flament C, Robert C, Maruyama K, Wakasugi H, Angevin E, Thielemans K, Le Cesne A, Chung-Scott V, Lazar V, Tchou I, Crépineau F, Lemoine F, Bernard J, Fletcher JA, Turhan A, Blay JY, Spatz A, Emile JF, Heinrich MC, Mécheri S, Tursz T, Zitvogel L.

J Clin Invest. 2004 Aug;114(3):379-88.

39.

NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.

Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, Ryffel B, Cambi A, Figdor C, Vainchenker W, Galy A, Caignard A, Zitvogel L.

Blood. 2004 Nov 15;104(10):3267-75. Epub 2004 Jul 8.

40.

IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules.

Terme M, Tomasello E, Maruyama K, Crépineau F, Chaput N, Flament C, Marolleau JP, Angevin E, Wagner EF, Salomon B, Lemonnier FA, Wakasugi H, Colonna M, Vivier E, Zitvogel L.

J Immunol. 2004 May 15;172(10):5957-66.

41.

The mouse natural killer T cell-associated antigen recognized by U5A2-13 monoclonal antibody is intercellular adhesion molecule-1.

Shimizu A, Sasaki H, Aoyagi K, Yoshida M, Kato K, Heike Y, Ikarashi Y, Shirakawa K, Takaue Y, Miyajima A, Terada M, Nagai H, Wakasugi H.

Immunol Lett. 2004 Apr 15;92(3):227-35.

PMID:
15081617
42.

Freeze-thawing procedures have no influence on the phenotypic and functional development of dendritic cells generated from peripheral blood CD14+ monocytes.

Hori S, Heike Y, Takei M, Maruyama M, Inoue Y, Lee JJ, Kim HJ, Harada Y, Kawai H, Shimosaka A, Kami M, Tanosaki MD, Wakasugi H, Saito S, Takaue Y, Kakizoe T.

J Immunother. 2004 Jan-Feb;27(1):27-35.

PMID:
14676631
43.

Immune reconstitution following reduced-intensity transplantation with cladribine, busulfan, and antithymocyte globulin: serial comparison with conventional myeloablative transplantation.

Saito T, Kanda Y, Nakai K, Kim SW, Arima F, Kami M, Tanosaki R, Tobinai K, Wakasugi H, Heike Y, Mineishi S, Takaue Y.

Bone Marrow Transplant. 2003 Sep;32(6):601-8.

PMID:
12953133
44.

CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responses.

Nishikawa H, Kato T, Tanida K, Hiasa A, Tawara I, Ikeda H, Ikarashi Y, Wakasugi H, Kronenberg M, Nakayama T, Taniguchi M, Kuribayashi K, Old LJ, Shiku H.

Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10902-6. Epub 2003 Aug 28.

45.

Antithymocyte globulin affects the occurrence of acute and chronic graft-versus-host disease after a reduced-intensity conditioning regimen by modulating mixed chimerism induction and immune reconstitution.

Nakai K, Mineishi S, Kami M, Saito T, Hori A, Kojima R, Imataki O, Hamaki T, Yoshihara S, Ohnishi M, Kim SW, Ando T, Fumitoh A, Kanda Y, Makimoto A, Tanosaki R, Kanai S, Heike Y, Ohnishi T, Kawano Y, Wakasugi H, Takaue Y.

Transplantation. 2003 Jun 27;75(12):2135-43.

PMID:
12829926
46.

Increased expansion of V alpha 24+ T cells derived from G-CSF-mobilized peripheral blood stem cells as compared to peripheral blood mononuclear cells following alpha-galactosylceramide stimulation.

Asada-Mikami R, Heike Y, Harada Y, Kanai S, Ikarashi Y, Kato K, Shirakawa K, Takaue Y, Abe T, Wakasugi H.

Cancer Sci. 2003 Apr;94(4):383-8.

47.

Determining the levels of matrix metalloproteinase-9 in portal and peripheral blood is useful for predicting liver metastasis of colorectal cancer.

Ishida H, Murata N, Tada M, Okada N, Hashimoto D, Kubota S, Shirakawa K, Wakasugi H.

Jpn J Clin Oncol. 2003 Apr;33(4):186-91.

PMID:
12810833
48.

Inflammatory breast cancer: vasculogenic mimicry and its hemodynamics of an inflammatory breast cancer xenograft model.

Shirakawa K, Kobayashi H, Sobajima J, Hashimoto D, Shimizu A, Wakasugi H.

Breast Cancer Res. 2003;5(3):136-9. Epub 2003 Mar 6.

49.

U5A2-13, an antigen originally found on mouse NK-like T cells, is an early inducible cell surface antigen during lymphoid activation.

Kato K, Ikarashi Y, Sugahara T, Yasumoto A, Sancho D, Yoshida M, Takaue Y, Kobayashi Y, Sánchez-Madrid F, Wakasugi H.

Cell Immunol. 2003 Jan;221(1):27-36.

PMID:
12742379
50.

Involvement of PKC betaII in anti-proliferating action of a new antitumor compound gnidimacrin.

Yoshida M, Heike Y, Ohno S, Ikekawa T, Wakasugi H.

Int J Cancer. 2003 Jul 10;105(5):601-6.

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