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Items: 1 to 50 of 256

1.

The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells.

Solari C, Petrone MV, Toro A, Vazquez Echegaray C, Cosentino MS, Waisman A, Francia M, Barañao L, Miriuka S, Guberman A.

BMC Res Notes. 2019 Jul 1;12(1):370. doi: 10.1186/s13104-019-4411-0.

2.

Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring.

Darby MG, Chetty A, Mrjden D, Rolot M, Smith K, Mackowiak C, Sedda D, Nyangahu D, Jaspan H, Toellner KM, Waisman A, Quesniaux V, Ryffel B, Cunningham AF, Dewals BG, Brombacher F, Horsnell WGC.

Sci Adv. 2019 May 29;5(5):eaav3058. doi: 10.1126/sciadv.aav3058. eCollection 2019 May.

3.

Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.

Timilshina M, You Z, Lacher SM, Acharya S, Jiang L, Kang Y, Kim JA, Chang HW, Kim KJ, Park B, Song JH, Ko HJ, Park YY, Ma MJ, Nepal MR, Jeong TC, Chung Y, Waisman A, Chang JH.

Cell Rep. 2019 Jun 4;27(10):2948-2961.e7. doi: 10.1016/j.celrep.2019.05.020.

4.

Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency.

Waisman A, Sevlever F, Elías Costa M, Cosentino MS, Miriuka SG, Ventura AC, Guberman AS.

Sci Rep. 2019 May 29;9(1):8051. doi: 10.1038/s41598-019-44537-0.

5.

Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase.

Xin W, Mironova YA, Shen H, Marino RAM, Waisman A, Lamers WH, Bergles DE, Bonci A.

Cell Rep. 2019 May 21;27(8):2262-2271.e5. doi: 10.1016/j.celrep.2019.04.094.

6.

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.

Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, Waisman A, Opitz L, Oukka M, Schreiner B, Pelczar P, Becher B.

Immunity. 2019 May 21;50(5):1289-1304.e6. doi: 10.1016/j.immuni.2019.04.006. Epub 2019 May 9.

PMID:
31079916
7.

A sequential interferon gamma directed chemotactic cellular immune response determines survival and cardiac function post myocardial infarction.

Finger S, Knorr M, Molitor M, Schüler R, Garlapati V, Waisman A, Brandt M, Münzel T, Bopp T, Kossmann S, Karbach S, Wenzel P.

Cardiovasc Res. 2019 Apr 5. pii: cvz092. doi: 10.1093/cvr/cvz092. [Epub ahead of print]

PMID:
30949687
8.

OTUB1 inhibits CNS autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes.

Wang X, Mulas F, Yi W, Brunn A, Nishanth G, Just S, Waisman A, Brück W, Deckert M, Schlüter D.

EMBO J. 2019 May 15;38(10). pii: e100947. doi: 10.15252/embj.2018100947. Epub 2019 Apr 3.

PMID:
30944096
9.

Deep Learning Neural Networks Highly Predict Very Early Onset of Pluripotent Stem Cell Differentiation.

Waisman A, La Greca A, Möbbs AM, Scarafía MA, Santín Velazque NL, Neiman G, Moro LN, Luzzani C, Sevlever GE, Guberman AS, Miriuka SG.

Stem Cell Reports. 2019 Apr 9;12(4):845-859. doi: 10.1016/j.stemcr.2019.02.004. Epub 2019 Mar 14.

10.

Kat6b Modulates Oct4 and Nanog Binding to Chromatin in Embryonic Stem Cells and Is Required for Efficient Neural Differentiation.

Cosentino MS, Oses C, Vázquez Echegaray C, Solari C, Waisman A, Álvarez Y, Petrone MV, Francia M, Schultz M, Sevlever G, Miriuka S, Levi V, Guberman A.

J Mol Biol. 2019 Mar 15;431(6):1148-1159. doi: 10.1016/j.jmb.2019.02.012. Epub 2019 Feb 18.

PMID:
30790630
11.

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.

Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G, Oellinger R, Zhan Y, Regen T, Hiltensperger M, Peter C, Aly L, Knier B, Palam LR, Kapur R, Kaplan MH, Waisman A, Rad R, Schotta G, Huehn J, Kallies A, Korn T.

Cell Rep. 2019 Feb 12;26(7):1854-1868.e5. doi: 10.1016/j.celrep.2019.01.070.

12.

IL-17A/F in Leishmania major-resistant C57BL/6 mice.

Dietze-Schwonberg K, Lopez Kostka S, Lorenz B, Regen T, Waisman A, von Stebut E.

Exp Dermatol. 2019 Mar;28(3):321-323. doi: 10.1111/exd.13896.

PMID:
30703249
13.

Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes.

Moos S, Mohebiany AN, Waisman A, Kurschus FC.

J Invest Dermatol. 2019 May;139(5):1110-1117. doi: 10.1016/j.jid.2019.01.006. Epub 2019 Jan 23.

PMID:
30684554
14.

Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.

Dmitrieva-Posocco O, Dzutsev A, Posocco DF, Hou V, Yuan W, Thovarai V, Mufazalov IA, Gunzer M, Shilovskiy IP, Khaitov MR, Trinchieri G, Waisman A, Grivennikov SI.

Immunity. 2019 Jan 15;50(1):166-180.e7. doi: 10.1016/j.immuni.2018.11.015.

PMID:
30650375
15.

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis.

Koliaraki V, Chalkidi N, Henriques A, Tzaferis C, Polykratis A, Waisman A, Muller W, Hackam DJ, Pasparakis M, Kollias G.

Cell Rep. 2019 Jan 15;26(3):536-545.e4. doi: 10.1016/j.celrep.2018.12.072.

16.

Impact of Secukinumab on Endothelial Dysfunction and Other Cardiovascular Disease Parameters in Psoriasis Patients over 52 Weeks.

von Stebut E, Reich K, Thaçi D, Koenig W, Pinter A, Körber A, Rassaf T, Waisman A, Mani V, Yates D, Frueh J, Sieder C, Melzer N, Mehta NN, Gori T.

J Invest Dermatol. 2019 May;139(5):1054-1062. doi: 10.1016/j.jid.2018.10.042. Epub 2018 Nov 30.

17.

MicroRNA characterization in equine induced pluripotent stem cells.

Moro LN, Amin G, Furmento V, Waisman A, Garate X, Neiman G, La Greca A, Santín Velazque NL, Luzzani C, Sevlever GE, Vichera G, Miriuka SG.

PLoS One. 2018 Dec 3;13(12):e0207074. doi: 10.1371/journal.pone.0207074. eCollection 2018.

18.

Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity.

Atretkhany KN, Mufazalov IA, Dunst J, Kuchmiy A, Gogoleva VS, Andruszewski D, Drutskaya MS, Faustman DL, Schwabenland M, Prinz M, Kruglov AA, Waisman A, Nedospasov SA.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13051-13056. doi: 10.1073/pnas.1807499115. Epub 2018 Nov 29.

19.

Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.

Wong R, Lénárt N, Hill L, Toms L, Coutts G, Martinecz B, Császár E, Nyiri G, Papaemmanouil A, Waisman A, Müller W, Schwaninger M, Rothwell N, Francis S, Pinteaux E, Denés A, Allan SM.

Brain Behav Immun. 2019 Feb;76:126-138. doi: 10.1016/j.bbi.2018.11.012. Epub 2018 Nov 16.

20.

Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice.

Elßner C, Goeppert B, Longerich T, Scherr AL, Stindt J, Nanduri LK, Rupp C, Kather JN, Schmitt N, Kautz N, Breuhahn K, Ismail L, Heide D, Hetzer J, García-Beccaria M, Hövelmeyer N, Waisman A, Urbanik T, Mueller S, Gdynia G, Banales JM, Roessler S, Schirmacher P, Jäger D, Schölch S, Keitel V, Heikenwalder M, Schulze-Bergkamen H, Köhler BC.

Gastroenterology. 2019 Mar;156(4):1190-1205.e14. doi: 10.1053/j.gastro.2018.11.018. Epub 2018 Nov 13.

PMID:
30445013
21.

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM.

Nature. 2018 Nov;563(7732):564-568. doi: 10.1038/s41586-018-0701-2. Epub 2018 Nov 7.

22.

Antigen-presenting cell diversity for T cell reactivation in central nervous system autoimmunity.

Waisman A, Johann L.

J Mol Med (Berl). 2018 Dec;96(12):1279-1292. doi: 10.1007/s00109-018-1709-7. Epub 2018 Nov 1. Review.

PMID:
30386908
23.

Antagonization of IL-17A Attenuates Skin Inflammation and Vascular Dysfunction in Mouse Models of Psoriasis.

Schüler R, Brand A, Klebow S, Wild J, Veras FP, Ullmann E, Roohani S, Kolbinger F, Kossmann S, Wohn C, Daiber A, Münzel T, Wenzel P, Waisman A, Clausen BE, Karbach S.

J Invest Dermatol. 2019 Mar;139(3):638-647. doi: 10.1016/j.jid.2018.09.021. Epub 2018 Oct 24.

PMID:
30367871
24.

Estrogen Signaling in Bystander Foxp3neg CD4+ T Cells Suppresses Cognate Th17 Differentiation in Trans and Protects from Central Nervous System Autoimmunity.

Garnier L, Laffont S, Lélu K, Yogev N, Waisman A, Guéry JC.

J Immunol. 2018 Dec 1;201(11):3218-3228. doi: 10.4049/jimmunol.1800417. Epub 2018 Oct 24.

PMID:
30355786
25.

Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis.

Tang Y, Reissig S, Glasmacher E, Regen T, Wanke F, Nikolaev A, Gerlach K, Popp V, Karram K, Fantini MC, Schattenberg JM, Galle PR, Neurath MF, Weigmann B, Kurschus FC, Hövelmeyer N, Waisman A.

Gastroenterology. 2019 Feb;156(3):692-707.e7. doi: 10.1053/j.gastro.2018.10.023. Epub 2018 Oct 10.

PMID:
30315770
26.

Evaluating the IgMi mouse as a novel tool to study B-cell biology.

Sahputra R, Yam-Puc JC, Waisman A, Muller W, Else KJ.

Eur J Immunol. 2018 Dec;48(12):2068-2071. doi: 10.1002/eji.201847735. Epub 2018 Oct 26.

PMID:
30315705
27.

The STATe of the Neuron Leads to Synaptic Stripping.

Mohebiany AN, Waisman A.

Neuron. 2018 Oct 10;100(1):16-18. doi: 10.1016/j.neuron.2018.09.036.

PMID:
30308168
28.

Aggravated Atherosclerosis and Vascular Inflammation With Reduced Kidney Function Depend on Interleukin-17 Receptor A and Are Normalized by Inhibition of Interleukin-17A.

Nordlohne J, Helmke A, Ge S, Rong S, Chen R, Waisman A, Haller H, von Vietinghoff S.

JACC Basic Transl Sci. 2018 Jan 10;3(1):54-66. doi: 10.1016/j.jacbts.2017.08.005. eCollection 2018 Feb.

29.

NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signaling.

Lacher SM, Thurm C, Distler U, Mohebiany AN, Israel N, Kitic M, Ebering A, Tang Y, Klein M, Wabnitz GH, Wanke F, Samstag Y, Bopp T, Kurschus FC, Simeoni L, Tenzer S, Waisman A.

J Autoimmun. 2018 Nov;94:110-121. doi: 10.1016/j.jaut.2018.07.017. Epub 2018 Jul 29.

PMID:
30061013
30.

Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice.

Gomez D, Baylis RA, Durgin BG, Newman AAC, Alencar GF, Mahan S, St Hilaire C, Müller W, Waisman A, Francis SE, Pinteaux E, Randolph GJ, Gram H, Owens GK.

Nat Med. 2018 Sep;24(9):1418-1429. doi: 10.1038/s41591-018-0124-5. Epub 2018 Jul 23.

31.

Expression of IL-17F is associated with non-pathogenic Th17 cells.

Wanke F, Tang Y, Gronke K, Klebow S, Moos S, Hauptmann J, Shanmugavadivu A, Regen T, Mufazalov IA, Gabriel LA, Reißig S, Diefenbach A, Kurschus FC, Waisman A.

J Mol Med (Berl). 2018 Aug;96(8):819-829. doi: 10.1007/s00109-018-1662-5. Epub 2018 Jun 29.

PMID:
29959474
32.

Sca-1+ cardiac fibroblasts promote development of heart failure.

Chen G, Bracamonte-Baran W, Diny NL, Hou X, Talor MV, Fu K, Liu Y, Davogustto G, Vasquez H, Taegtmeyer H, Frazier OH, Waisman A, Conway SJ, Wan F, Čiháková D.

Eur J Immunol. 2018 Sep;48(9):1522-1538. doi: 10.1002/eji.201847583. Epub 2018 Jul 18.

PMID:
29953616
33.

Superoxide dismutase 1 expression is modulated by the core pluripotency transcription factors Oct4, Sox2 and Nanog in embryonic stem cells.

Solari C, Petrone MV, Vazquez Echegaray C, Cosentino MS, Waisman A, Francia M, Barañao L, Miriuka S, Guberman A.

Mech Dev. 2018 Dec;154:116-121. doi: 10.1016/j.mod.2018.06.004. Epub 2018 Jun 19.

PMID:
29933066
34.

Conditional Gene-Targeting in Mice: Problems and Solutions.

Becher B, Waisman A, Lu LF.

Immunity. 2018 May 15;48(5):835-836. doi: 10.1016/j.immuni.2018.05.002. No abstract available.

35.

Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment.

Wunderlich CM, Ackermann PJ, Ostermann AL, Adams-Quack P, Vogt MC, Tran ML, Nikolajev A, Waisman A, Garbers C, Theurich S, Mauer J, Hövelmeyer N, Wunderlich FT.

Nat Commun. 2018 Apr 25;9(1):1646. doi: 10.1038/s41467-018-03773-0.

36.

[Mutual influence of immune system and bones].

Kamradt T, Amling M, Dankbar B, Dudeck A, Gunzer M, Ignatius A, Krönke G, Kubatzky K, Pap T, Prinz I, Schett G, Schinke T, Tuckermann J, Waisman A.

Z Rheumatol. 2018 May;77(Suppl 1):8-11. doi: 10.1007/s00393-018-0454-1. Review. German. No abstract available.

PMID:
29675686
37.

RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation.

Bartsch K, Damme M, Regen T, Becker L, Garrett L, Hölter SM, Knittler K, Borowski C, Waisman A, Glatzel M, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Rabe B.

Front Immunol. 2018 Mar 29;9:587. doi: 10.3389/fimmu.2018.00587. eCollection 2018.

38.

Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation.

Li H, Yao Q, Mariscal AG, Wu X, Hülse J, Pedersen E, Helin K, Waisman A, Vinkel C, Thomsen SF, Avgustinova A, Benitah SA, Lovato P, Norsgaard H, Mortensen MS, Veng L, Rozell B, Brakebusch C.

Nat Commun. 2018 Apr 12;9(1):1420. doi: 10.1038/s41467-018-03704-z.

39.

PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.

Dörsam B, Seiwert N, Foersch S, Stroh S, Nagel G, Begaliew D, Diehl E, Kraus A, McKeague M, Minneker V, Roukos V, Reißig S, Waisman A, Moehler M, Stier A, Mangerich A, Dantzer F, Kaina B, Fahrer J.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4061-E4070. doi: 10.1073/pnas.1712345115. Epub 2018 Apr 9.

40.

Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility.

Larson VA, Mironova Y, Vanderpool KG, Waisman A, Rash JE, Agarwal A, Bergles DE.

Elife. 2018 Mar 29;7. pii: e34829. doi: 10.7554/eLife.34829.

41.

A predominantly glial origin of axonal ribosomes after nerve injury.

Müller K, Schnatz A, Schillner M, Woertge S, Müller C, von Graevenitz I, Waisman A, van Minnen J, Vogelaar CF.

Glia. 2018 Aug;66(8):1591-1610. doi: 10.1002/glia.23327. Epub 2018 Mar 25.

PMID:
29575063
42.

Wheat amylase-trypsin inhibitors exacerbate intestinal and airway allergic immune responses in humanized mice.

Bellinghausen I, Weigmann B, Zevallos V, Maxeiner J, Reißig S, Waisman A, Schuppan D, Saloga J.

J Allergy Clin Immunol. 2019 Jan;143(1):201-212.e4. doi: 10.1016/j.jaci.2018.02.041. Epub 2018 Mar 21.

PMID:
29574077
43.

Population snapshots predict early haematopoietic and erythroid hierarchies.

Tusi BK, Wolock SL, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, Waisman A, Huh JR, Klein AM, Socolovsky M.

Nature. 2018 Mar 1;555(7694):54-60. doi: 10.1038/nature25741. Epub 2018 Feb 21.

44.

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal.

Weng SY, Wang X, Vijayan S, Tang Y, Kim YO, Padberg K, Regen T, Molokanova O, Chen T, Bopp T, Schild H, Brombacher F, Crosby JR, McCaleb ML, Waisman A, Bockamp E, Schuppan D.

EBioMedicine. 2018 Mar;29:92-103. doi: 10.1016/j.ebiom.2018.01.028. Epub 2018 Feb 17.

45.

PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling.

González-Fernández E, Jeong HK, Fukaya M, Kim H, Khawaja RR, Srivastava IN, Waisman A, Son YJ, Kang SH.

Elife. 2018 Feb 20;7. pii: e32021. doi: 10.7554/eLife.32021.

46.

Inhibition of experimental autoimmune encephalomyelitis by tolerance-promoting DNA vaccination focused to dendritic cells.

Castor T, Yogev N, Blank T, Barwig C, Prinz M, Waisman A, Bros M, Reske-Kunz AB.

PLoS One. 2018 Feb 6;13(2):e0191927. doi: 10.1371/journal.pone.0191927. eCollection 2018.

47.

Hepatocyte-specific deletion of IL1-RI attenuates liver injury by blocking IL-1 driven autoinflammation.

Gehrke N, Hövelmeyer N, Waisman A, Straub BK, Weinmann-Menke J, Wörns MA, Galle PR, Schattenberg JM.

J Hepatol. 2018 May;68(5):986-995. doi: 10.1016/j.jhep.2018.01.008. Epub 2018 Jan 31.

PMID:
29366909
48.

A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.

Serr I, Scherm MG, Zahm AM, Schug J, Flynn VK, Hippich M, Kälin S, Becker M, Achenbach P, Nikolaev A, Gerlach K, Liebsch N, Loretz B, Lehr CM, Kirchner B, Spornraft M, Haase B, Segars J, Küper C, Palmisano R, Waisman A, Willis RA, Kim WU, Weigmann B, Kaestner KH, Ziegler AG, Daniel C.

Sci Transl Med. 2018 Jan 3;10(422). pii: eaag1782. doi: 10.1126/scitranslmed.aag1782. Erratum in: Sci Transl Med. 2019 Feb 20;11(480):.

49.

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin.

Verma AH, Richardson JP, Zhou C, Coleman BM, Moyes DL, Ho J, Huppler AR, Ramani K, McGeachy MJ, Mufazalov IA, Waisman A, Kane LP, Biswas PS, Hube B, Naglik JR, Gaffen SL.

Sci Immunol. 2017 Nov 3;2(17). pii: eaam8834. doi: 10.1126/sciimmunol.aam8834.

50.

Sox8 and Sox10 jointly maintain myelin gene expression in oligodendrocytes.

Turnescu T, Arter J, Reiprich S, Tamm ER, Waisman A, Wegner M.

Glia. 2018 Feb;66(2):279-294. doi: 10.1002/glia.23242. Epub 2017 Oct 11.

PMID:
29023979

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