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Items: 1 to 50 of 111

1.

Metabolism and Disposition of 2-Hydroxy-4-Methoxybenzophenone, a Sunscreen Ingredient, in Harlan Sprague Dawley Rats and B6C3F1/N Mice; a Species and Route Comparison.

Mutlu E, Garner CE, Wegerski CJ, McDonald JD, McIntyre BS, Doyle-Eisele M, Waidyanatha S.

Xenobiotica. 2019 Oct 15:1-49. doi: 10.1080/00498254.2019.1680906. [Epub ahead of print]

PMID:
31613170
2.

Toxicokinetics of 8:2 fluorotelomer alcohol (8:2-FTOH) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration.

Huang MC, Robinson VG, Waidyanatha S, Dzierlenga AL, DeVito MJ, Eifrid MA, Gibbs ST, Blystone CR.

Toxicol Rep. 2019 Aug 20;6:924-932. doi: 10.1016/j.toxrep.2019.08.009. eCollection 2019.

3.

Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data.

Ryan KR, Huang MC, Ferguson SS, Waidyanatha S, Ramaiahgari S, Rice JR, Dunlap PE, Auerbach SS, Mutlu E, Cristy T, Peirfelice J, DeVito MJ, Smith-Roe SL, Rider CV.

Toxicol Sci. 2019 Aug 27. pii: kfz189. doi: 10.1093/toxsci/kfz189. [Epub ahead of print]

PMID:
31504990
4.

Toxicokinetics and bioavailability of sulfolane, a ground water contaminant, following oral and intravenous administration in rodents: A dose, species, and sex comparison.

Waidyanatha S, Black SR, Fennell TR, Watson SL, Patel PR, Cooper SD, Blake J, Robinson VG, Fernando RA, Blystone CR.

Toxicol Appl Pharmacol. 2019 Sep 15;379:114690. doi: 10.1016/j.taap.2019.114690. Epub 2019 Jul 22.

PMID:
31344372
5.

Toxicokinetics of perfluorobutane sulfonate (PFBS), perfluorohexane-1-sulphonic acid (PFHxS), and perfluorooctane sulfonic acid (PFOS) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration.

Huang MC, Dzierlenga AL, Robinson VG, Waidyanatha S, DeVito MJ, Eifrid MA, Granville CA, Gibbs ST, Blystone CR.

Toxicol Rep. 2019 Jun 28;6:645-655. doi: 10.1016/j.toxrep.2019.06.016. eCollection 2019.

6.

Systemic exposure to Ginkgo biloba extract in male F344/NCrl rats: Relevance to humans.

Waidyanatha S, Mutlu E, Gibbs S, Stiffler B, Andre J, Burback B, Rider CV.

Food Chem Toxicol. 2019 Sep;131:110586. doi: 10.1016/j.fct.2019.110586. Epub 2019 Jun 14.

PMID:
31202939
7.

Disposition and metabolism of sulfolane in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans.

Waidyanatha S, Black SR, Blystone CR, Patel PR, Watson SL, Snyder RW, Fennell TR.

Xenobiotica. 2019 Jul 5:1-12. doi: 10.1080/00498254.2019.1630786. [Epub ahead of print]

PMID:
31184953
8.

Comparative disposition of dimethylaminoethanol and choline in rats and mice following oral or intravenous administration.

Shipkowski KA, Sanders JM, McDonald JD, Garner CE, Doyle-Eisele M, Wegerski CJ, Waidyanatha S.

Toxicol Appl Pharmacol. 2019 Sep 1;378:114592. doi: 10.1016/j.taap.2019.05.011. Epub 2019 May 14.

PMID:
31100288
9.

Development and Validation of an Analytical Method for Quantitation of Sulfolane in Rat and Mouse Plasma by GC-MS.

Silinski MAR, Uenoyama T, Cooper SD, Fernando RA, Robinson VG, Waidyanatha S.

J Anal Toxicol. 2019 Jul 24;43(6):477-481. doi: 10.1093/jat/bkz031.

PMID:
31044244
10.

Toxicokinetics and bioavailability of bisphenol AF following oral administration in rodents: A dose, species, and sex comparison.

Waidyanatha S, Black SR, Aillon K, Collins B, Patel PR, Riordan F, Sutherland V, Robinson VG, Fernando R, Fennell TR.

Toxicol Appl Pharmacol. 2019 Jun 15;373:39-47. doi: 10.1016/j.taap.2019.04.015. Epub 2019 May 3.

PMID:
31022493
11.

Mutational analysis of pentabrominated diphenyl-induced hepatocellular tumors in rats and mice, tissue levels of PBDE congeners in rats and mice, and AhR genotyping of Wistar Han rats.

Dunnick JK, Pandiri AR, Merrick BA, Kissling GE, Cunny H, Mutlu E, Waidyanatha S, Sills RC, Hong HL, Ton TV, Maynor T, Rescio L, Phillips SL, Devito MJ, Brix A.

Data Brief. 2018 Oct 28;21:2125-2128. doi: 10.1016/j.dib.2018.10.104. eCollection 2018 Dec.

12.

Response to the letter to the editor for embryo-fetal development studies with the dietary supplement vinpocetine in the rat and rabbit.

Catlin N, Waidyanatha S, Mylchreest E, Miller-Pinsler L, Cunny H, Foster P, Sutherland V, McIntyre B.

Birth Defects Res. 2018 Nov 1;110(18):1374-1375. doi: 10.1002/bdr2.1401. Epub 2018 Oct 25. No abstract available.

PMID:
30362271
13.

Disposition of fullerene C60 in rats following intratracheal or intravenous administration.

Shipkowski KA, Sanders JM, McDonald JD, Walker NJ, Waidyanatha S.

Xenobiotica. 2019 Sep;49(9):1078-1085. doi: 10.1080/00498254.2018.1528646. Epub 2019 Apr 12.

PMID:
30257131
14.

PBDE-47 and PBDE mixture (DE-71) toxicities and liver transcriptomic changes at PND 22 after in utero/postnatal exposure in the rat.

Dunnick JK, Shockley KR, Pandiri AR, Kissling GE, Gerrish KE, Ton TV, Wilson RE, Brar SS, Brix AE, Waidyanatha S, Mutlu E, Morgan DL.

Arch Toxicol. 2018 Nov;92(11):3415-3433. doi: 10.1007/s00204-018-2292-y. Epub 2018 Sep 5.

15.

Follow that botanical: Challenges and recommendations for assessing absorption, distribution, metabolism and excretion of botanical dietary supplements.

Waidyanatha S, Ryan K, Roe AL, Jia W, Paine MF, Ferguson S, Gurley BJ, Welch K, Chow MSS, Devito M, Rider C.

Food Chem Toxicol. 2018 Nov;121:194-202. doi: 10.1016/j.fct.2018.08.062. Epub 2018 Aug 28.

PMID:
30170118
16.

Development and Validation of an Analytical Method to Quantitate Tris(chloroisopropyl)phosphate in Rat and Mouse Plasma using Gas Chromatography with Flame Photometric Detection.

Collins BJ, Slade D, Ryan K, Mathias R, Shan A, Algaier J, Aillon K, Waidyanatha S.

J Anal Toxicol. 2019 Jan 1;43(1):36-44. doi: 10.1093/jat/bky048.

PMID:
30060005
17.

Carcinogenic activity of pentabrominated diphenyl ether mixture (DE-71) in rats and mice.

Dunnick JK, Pandiri AR, Merrick BA, Kissling GE, Cunny H, Mutlu E, Waidyanatha S, Sills R, Hong HL, Ton TV, Maynor T, Recio L, Phillips SL, Devito MJ, Brix A.

Toxicol Rep. 2018 May 25;5:615-624. doi: 10.1016/j.toxrep.2018.05.010. eCollection 2018.

18.

Clarification and lessons learned for reporting studies with hydrates. Citation: Roberts et al., 2016. Toxicology Reports 3: 531-538.

Roberts GK, Stout MD, Sayers B, Fallacara DM, Hejtmancik MR, Waidyanatha S, Hooth MJ.

Toxicol Rep. 2017 Dec 30;5:207-208. doi: 10.1016/j.toxrep.2017.12.023. eCollection 2018. No abstract available.

19.

Reduced Disc Shedding and Phagocytosis of Photoreceptor Outer Segment Contributes to Kava Kava Extract-induced Retinal Degeneration in F344/N Rats.

Yamashita H, Hoenerhoff MJ, Shockley KR, Peddada SD, Gerrish KE, Sutton D, Cummings CA, Wang Y, Julie FF, Behl M, Waidyanatha S, Sills RC, Pandiri AR.

Toxicol Pathol. 2018 Jul;46(5):564-573. doi: 10.1177/0192623318778796. Epub 2018 May 27.

20.

Disposition and metabolism of the bisphenol analogue, bisphenol S, in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans.

Waidyanatha S, Black SR, Snyder RW, Yueh YL, Sutherland V, Patel PR, Watson SL, Fennell TR.

Toxicol Appl Pharmacol. 2018 Jul 15;351:32-45. doi: 10.1016/j.taap.2018.05.008. Epub 2018 May 18.

PMID:
29753715
21.

How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract.

Catlin NR, Collins BJ, Auerbach SS, Ferguson SS, Harnly JM, Gennings C, Waidyanatha S, Rice GE, Smith-Roe SL, Witt KL, Rider CV.

Food Chem Toxicol. 2018 Aug;118:328-339. doi: 10.1016/j.fct.2018.05.013. Epub 2018 May 9.

PMID:
29752982
22.

Getting to the Root of the Matter: Challenges and Recommendations for Assessing the Safety of Botanical Dietary Supplements.

Rider CV, Walker NJ, Waidyanatha S.

Clin Pharmacol Ther. 2018 Sep;104(3):429-431. doi: 10.1002/cpt.1088. Epub 2018 May 10.

23.

Black cohosh extracts and powders induce micronuclei, a biomarker of genetic damage, in human cells.

Smith-Roe SL, Swartz CD, Shepard KG, Bryce SM, Dertinger SD, Waidyanatha S, Kissling GE, Auerbach SS, Witt KL.

Environ Mol Mutagen. 2018 Jun;59(5):416-426. doi: 10.1002/em.22182. Epub 2018 Apr 18.

24.

Disposition of tris(4-chlorophenyl)methanol and tris(4-chlorophenyl)methane in male and female Harlan Sprague Dawley rats and B6C3F1/N mice following oral and intravenous administration.

Catlin NR, Waidyanatha S, Black SR, Mathews JM, Snyder RW, Patel PR, Watson SL, Fennell TR.

Xenobiotica. 2019 Apr;49(4):484-494. doi: 10.1080/00498254.2018.1463475. Epub 2018 May 3.

PMID:
29659319
25.

Embryo-fetal development studies with the dietary supplement vinpocetine in the rat and rabbit.

Catlin N, Waidyanatha S, Mylchreest E, Miller-Pinsler L, Cunny H, Foster P, Sutherland V, McIntyre B.

Birth Defects Res. 2018 Jun 1;110(10):883-896. doi: 10.1002/bdr2.1207. Epub 2018 Feb 19.

26.

Disposition of β-N-methylamino-l-alanine (L-BMAA), a neurotoxin, in rodents following a single or repeated oral exposure.

Waidyanatha S, Ryan K, Sanders JM, McDonald JD, Wegerski CJ, Doyle-Eisle M, Garner CE.

Toxicol Appl Pharmacol. 2018 Jan 15;339:151-160. doi: 10.1016/j.taap.2017.12.008. Epub 2017 Dec 15.

PMID:
29248465
27.

Disposition of [14C]hydroquinone in Harlan Sprague-Dawley rats and B6C3F1/N mice: species and route comparison.

Black SR, Fennell TR, Mathews JM, Snyder RW, Patel PR, Watson SL, Sutherland V, Waidyanatha S.

Xenobiotica. 2018 Nov;48(11):1128-1141. doi: 10.1080/00498254.2017.1398847. Epub 2017 Nov 22.

PMID:
29166815
28.

Systemic exposure of vinpocetine in pregnant Sprague Dawley rats following repeated oral exposure: An investigation of fetal transfer.

Waidyanatha S, Toy H, South N, Gibbs S, Mutlu E, Burback B, McIntyre BS, Catlin N.

Toxicol Appl Pharmacol. 2018 Jan 1;338:83-92. doi: 10.1016/j.taap.2017.11.011. Epub 2017 Nov 15.

PMID:
29155086
29.

Metabolism and disposition of 2-ethylhexyl-p-methoxycinnamate following oral gavage and dermal exposure in Harlan Sprague Dawley rats and B6C3F1/N mice and in hepatocytes in vitro.

Fennell TR, Mathews JM, Snyder RW, Hong Y, Watson SL, Black SR, McIntyre BS, Waidyanatha S.

Xenobiotica. 2018 Nov;48(11):1142-1156. doi: 10.1080/00498254.2017.1400129. Epub 2017 Nov 23.

PMID:
29111853
30.

Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Ramaiahgari SC, Waidyanatha S, Dixon D, DeVito MJ, Paules RS, Ferguson SS.

Toxicol Sci. 2017 Nov 1;160(1):189-190. doi: 10.1093/toxsci/kfx194. No abstract available.

PMID:
29077947
31.

Evaluation of the respiratory tract toxicity of ortho-phthalaldehyde, a proposed alternative for the chemical disinfectant glutaraldehyde.

Catlin NR, Willson CJ, Stout M, Kissling GE, Waidyanatha S, Baker GL, Hayden BK, Wyde M.

Inhal Toxicol. 2017 Aug;29(9):414-427. doi: 10.1080/08958378.2017.1390015. Epub 2017 Oct 17.

PMID:
29039228
32.

Simultaneous Quantitation of 2-Hydroxy-4-Methoxybenzophenone, a Sunscreen Ingredient, and its Metabolites in Harlan Sprague Dawley Rat Plasma Following Perinatal Dietary Exposure.

Mutlu E, Pierfelice J, McIntyre BS, Cunny HC, Kissling GE, Burback B, Waidyanatha S.

J Anal Toxicol. 2017 Nov 1;41(9):744-754. doi: 10.1093/jat/bkx070.

33.

Exposure to butyl paraben during gestation and lactation in Hsd:Sprague dawley SD rats via dosed feed.

Roberts GK, Waidyanatha S, Kissling GE, Fletcher BL, Silinski MAR, Fennell TR, Cunny HC, Robinson VG, Blystone CR.

Toxicol Rep. 2016 Sep 11;3:774-783. doi: 10.1016/j.toxrep.2016.09.004. eCollection 2016.

34.

Lipoprotein Lipase Deficiency in an Infant With Chylomicronemia, Hepatomegaly, and Lipemia Retinalis.

Vidanapathirana DM, Rodrigo T, Waidyanatha S, Jasinge E, Hooper AJ, Burnett JR.

Glob Pediatr Health. 2017 Jun 28;4:2333794X17715839. doi: 10.1177/2333794X17715839. eCollection 2017. No abstract available.

35.

From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Ramaiahgari SC, Waidyanatha S, Dixon D, DeVito MJ, Paules RS, Ferguson SS.

Toxicol Sci. 2017 Sep 1;159(1):124-136. doi: 10.1093/toxsci/kfx122. Erratum in: Toxicol Sci. 2017 Nov 1;160(1):189-190.

36.

A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice.

Cora MC, Gwinn W, Wilson R, King D, Waidyanatha S, Kissling GE, Brar SS, Olivera D, Blystone C, Travlos G.

Toxicol Pathol. 2017 Jul;45(5):614-623. doi: 10.1177/0192623317714343. Epub 2017 Jun 15.

37.

Evaluation of 4-methylcyclohexanemethanol (MCHM) in a combined irritancy and Local Lymph Node Assay (LLNA) in mice.

Johnson VJ, Auerbach SS, Luster MI, Waidyanatha S, Masten SA, Wolfe MS, Burleson FG, Burleson GR, Germolec DR.

Food Chem Toxicol. 2017 Jul;105:99-105. doi: 10.1016/j.fct.2017.03.034. Epub 2017 Mar 22.

38.

14-Day Toxicity Studies of Tetravalent and Pentavalent Vanadium Compounds in Harlan Sprague Dawley Rats and B6C3F1/N Mice via Drinking Water Exposure.

Roberts GK, Stout MD, Sayers B, Fallacara DM, Hejtmancik MR, Waidyanatha S, Hooth MJ.

Toxicol Rep. 2016;3:531-538. doi: 10.1016/j.toxrep.2016.05.001. Epub 2016 May 12.

39.

Characterization of Zinc Carbonate Basic as a Source of Zinc in a Rodent Study Investigating the Effects of Dietary Deficiency or Excess.

Levine KE, Collins BJ, Stout MD, Wyde M, Afton SE, Essader AS, Ennis TJ, Amato KE, McWilliams AC, Fletcher BL, Fernando RA, Harrington JM, Catlin N, Robinson VG, Waidyanatha S.

Anal Lett. 2017;50(15):2447-2464. doi: 10.1080/00032719.2017.1293073. Epub 2017 Jun 22.

40.

Characterization of aqueous formulations of tetra- and pentavalent forms of vanadium in support of test article selection in toxicology studies.

Mutlu E, Cristy T, Graves SW, Hooth MJ, Waidyanatha S.

Environ Sci Pollut Res Int. 2017 Jan;24(1):405-416. doi: 10.1007/s11356-016-7803-x. Epub 2016 Oct 10.

PMID:
27726079
41.

Dermal Exposure to Cumene Hydroperoxide: Assessing Its Toxic Relevance and Oxidant Potential.

Rider CV, Chan P, Herbert RA, Kissling GE, Fomby LM, Hejtmancik MR, Witt KL, Waidyanatha S, Travlos GS, Kadiiska MB.

Toxicol Pathol. 2016 Jul;44(5):749-62. doi: 10.1177/0192623316636712. Epub 2016 Mar 16.

42.

Development, validation, and application of an ultra-performance liquid chromatography-sector field inductively coupled plasma mass spectrometry method for simultaneous determination of six organotin compounds in human serum.

Levine KE, Young DJ, Afton SE, Harrington JM, Essader AS, Weber FX, Fernando RA, Thayer K, Hatch EE, Robinson VG, Waidyanatha S.

Talanta. 2015 Aug 1;140:115-121. doi: 10.1016/j.talanta.2015.03.022. Epub 2015 Mar 27.

PMID:
26048832
43.

Disposition of bisphenol AF, a bisphenol A analogue, in hepatocytes in vitro and in male and female Harlan Sprague-Dawley rats and B6C3F1/N mice following oral and intravenous administration.

Waidyanatha S, Mathews JM, Patel PR, Black SR, Snyder RW, Fennell TR.

Xenobiotica. 2015;45(9):811-9. doi: 10.3109/00498254.2015.1021732. Epub 2015 Jun 12.

PMID:
25923777
44.

Systemic uptake, albumin and hemoglobin binding of [(14)C]2,3-butanedione administered by intratracheal instillation in male Harlan Sprague Dawley rats and oropharyngeal aspiration in male B6C3F1/N mice.

Fennell TR, Morgan DL, Watson SL, Dhungana S, Waidyanatha S.

Chem Biol Interact. 2015 Feb 5;227:112-9. doi: 10.1016/j.cbi.2014.12.029. Epub 2015 Jan 2.

PMID:
25559854
45.

Formation of epichlorohydrin, a known rodent carcinogen, following oral administration of 1,3-dichloro-2-propanol in rats.

Waidyanatha S, Gaudette NF, Hong Y, Fennell TR.

Chem Res Toxicol. 2014 Oct 20;27(10):1787-95. doi: 10.1021/tx500239q. Epub 2014 Oct 9.

46.
47.

Metabolism and disposition of [(14)C]dimethylamine borane in male Harlan Sprague Dawley rats following gavage administration, intravenous administration and dermal application.

Mathews JM, Watson SL, Patel PR, Black SR, Hong Y, Levine KE, Ross G, Germolec DR, Thakur SA, Waidyanatha S.

Xenobiotica. 2014 Jan;44(1):36-47. doi: 10.3109/00498254.2013.800662. Epub 2013 Jun 20.

PMID:
23786350
48.

Toxicokinetics of α-thujone following intravenous and gavage administration of α-thujone or α- and β-thujone mixture in male and female F344/N rats and B6C3F1 mice.

Waidyanatha S, Johnson JD, Hong SP, Robinson VG, Gibbs S, Graves SW, Hooth MJ, Smith CS.

Toxicol Appl Pharmacol. 2013 Sep 1;271(2):216-28. doi: 10.1016/j.taap.2013.05.001. Epub 2013 May 10.

PMID:
23669748
49.

Toxicokinetics of isoeugenol in F344 rats and B6C3F1 mice.

Hong SP, Fuciarelli AF, Johnson JD, Graves SW, Bates DJ, Smith CS, Waidyanatha S.

Xenobiotica. 2013 Nov;43(11):1010-7. doi: 10.3109/00498254.2013.790576. Epub 2013 Apr 29.

PMID:
23627552
50.

Toxicokinetics of methyleugenol in F344 rats and B6C3F₁ mice.

Hong SP, Fuciarelli AF, Johnson JD, Graves SW, Bates DJ, Waidyanatha S, Smith CS.

Xenobiotica. 2013 Mar;43(3):293-302. doi: 10.3109/00498254.2012.711496. Epub 2012 Aug 10.

PMID:
22876784

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