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Items: 20


A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, Giorgi FM, Califano A, Rinn JL, Meissner A, Hirschhorn JN, Daley GQ.

Cell Stem Cell. 2018 Apr 5;22(4):575-588.e7. doi: 10.1016/j.stem.2018.03.012.


Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.

Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ.

Sci Transl Med. 2017 Feb 8;9(376). pii: eaah5645. doi: 10.1126/scitranslmed.aah5645.


Using tuberous sclerosis complex to understand the impact of MTORC1 signaling on mitochondrial dynamics and mitophagy in neurons.

Ebrahimi-Fakhari D, Saffari A, Wahlster L, Sahin M.

Autophagy. 2017 Apr 3;13(4):754-756. doi: 10.1080/15548627.2016.1277310. Epub 2017 Jan 25.


Impaired Mitochondrial Dynamics And Mitophagy In Neuronal Models Of Tuberous Sclerosis Complex.

Ebrahimi-Fakhari D, Saffari A, Wahlster L, DiNardo A, Turner D, Lewis TL Jr, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M.

Cell Rep. 2016 Nov 15;17(8):2162. doi: 10.1016/j.celrep.2016.10.051. No abstract available.


Progress towards generation of human haematopoietic stem cells.

Wahlster L, Daley GQ.

Nat Cell Biol. 2016 Nov;18(11):1111-1117. doi: 10.1038/ncb3419. Epub 2016 Oct 10. Review.


Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex.

Ebrahimi-Fakhari D, Saffari A, Wahlster L, Di Nardo A, Turner D, Lewis TL Jr, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M.

Cell Rep. 2016 Oct 18;17(4):1053-1070. doi: 10.1016/j.celrep.2016.09.054. Erratum in: Cell Rep. 2016 Nov 15;17 (8):2162.


Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells.

Ebrahimi-Fakhari D, Wahlster L, Bartz F, Werenbeck-Ueding J, Praggastis M, Zhang J, Joggerst-Thomalla B, Theiss S, Grimm D, Ory DS, Runz H.

Hum Mol Genet. 2016 Aug 15;25(16):3588-3599. doi: 10.1093/hmg/ddw204. Epub 2016 Jul 4.


Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism.

Ebrahimi-Fakhari D, Saffari A, Wahlster L, Lu J, Byrne S, Hoffmann GF, Jungbluth H, Sahin M.

Brain. 2016 Feb;139(Pt 2):317-37. doi: 10.1093/brain/awv371. Epub 2015 Dec 29. Review.


Parkinson's disease: A disorder of axonal mitophagy?

Ebrahimi-Fakhari D, Wahlster L, Sahin M.

Mov Disord. 2014 Nov;29(13):1582. doi: 10.1002/mds.26047. Epub 2014 Sep 25. No abstract available.


International electives in the final year of German medical school education--a student's perspective.

Ebrahimi-Fakhari D, Agrawal M, Wahlster L.

GMS Z Med Ausbild. 2014 Aug 15;31(3):Doc26. doi: 10.3205/zma000918. eCollection 2014.


Modeling Parkinson's disease in a dish--a story of yeast and men.

Ebrahimi-Fakhari D, Wahlster L.

Mov Disord. 2014 Jan;29(1):34. doi: 10.1002/mds.25781. Epub 2013 Dec 20. No abstract available.


Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies.

Ebrahimi-Fakhari D, Saidi LJ, Wahlster L.

Acta Neuropathol Commun. 2013 Dec 5;1:79. doi: 10.1186/2051-5960-1-79. Review.


Emerging role of autophagy in pediatric neurodegenerative and neurometabolic diseases.

Ebrahimi-Fakhari D, Wahlster L, Hoffmann GF, Kölker S.

Pediatr Res. 2014 Jan;75(1-2):217-26. doi: 10.1038/pr.2013.185. Epub 2013 Oct 28. Review. Erratum in: Pediatr Res. 2014 Sep;76(3):323.


Restoring impaired protein metabolism in Parkinson's disease--TFEB-mediated autophagy as a novel therapeutic target.

Ebrahimi-Fakhari D, Wahlster L.

Mov Disord. 2013 Sep;28(10):1346. doi: 10.1002/mds.25601. No abstract available.


Proteotoxicity and cardiac dysfunction.

Ebrahimi-Fakhari D, McLean PJ, Wahlster L.

N Engl J Med. 2013 May 2;368(18):1754. doi: 10.1056/NEJMc1302511. No abstract available.


Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease.

Wahlster L, Arimon M, Nasser-Ghodsi N, Post KL, Serrano-Pozo A, Uemura K, Berezovska O.

Acta Neuropathol. 2013 Feb;125(2):187-99. doi: 10.1007/s00401-012-1065-6. Epub 2012 Nov 9.


Familial Mediterranean fever in Germany: clinical presentation and amyloidosis risk.

Ebrahimi-Fakhari D, Schönland SO, Hegenbart U, Lohse P, Beimler J, Wahlster L, Ho AD, Lorenz HM, Blank N.

Scand J Rheumatol. 2013;42(1):52-8. doi: 10.3109/03009742.2012.714796. Epub 2012 Nov 8.


Protein degradation pathways in Parkinson's disease: curse or blessing.

Ebrahimi-Fakhari D, Wahlster L, McLean PJ.

Acta Neuropathol. 2012 Aug;124(2):153-72. doi: 10.1007/s00401-012-1004-6. Epub 2012 Jun 29. Review.


Molecular chaperones in Parkinson's disease--present and future.

Ebrahimi-Fakhari D, Wahlster L, McLean PJ.

J Parkinsons Dis. 2011;1(4):299-320. Review.


Clinical manifestations and longterm followup of a patient with CINCA/NOMID syndrome.

Ebrahimi-Fakhari D, Wahlster L, Mackensen F, Blank N.

J Rheumatol. 2010 Oct;37(10):2196-7. doi: 10.3899/jrheum.100290. No abstract available.


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