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Items: 45


Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast.

Storey AJ, Wang HP, Protacio RU, Davidson MK, Wahls WP.

G3 (Bethesda). 2019 Dec 3;9(12):4097-4106. doi: 10.1534/g3.119.400805.


Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway.

Mukiza TO, Protacio RU, Davidson MK, Steiner WW, Wahls WP.

Genetics. 2019 Nov;213(3):789-803. doi: 10.1534/genetics.119.302679. Epub 2019 Sep 11.


Opinion: The National Institutes of Health needs to better balance funding distributions among US institutions.

Wahls WP.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13150-13154. doi: 10.1073/pnas.1909217116. No abstract available.


NIH dollars go to too few US states.

Wahls WP.

Nature. 2018 Dec;564(7735):190. doi: 10.1038/d41586-018-07722-1. No abstract available.


Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot.

Storey AJ, Wang HP, Protacio RU, Davidson MK, Tackett AJ, Wahls WP.

Epigenetics Chromatin. 2018 Oct 29;11(1):64. doi: 10.1186/s13072-018-0233-x.


In Vivo Metabolic Tracing Demonstrates the Site-Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation.

Kriss CL, Gregory-Lott E, Storey AJ, Tackett AJ, Wahls WP, Stevens SM Jr.

Alcohol Clin Exp Res. 2018 Oct;42(10):1909-1923. doi: 10.1111/acer.13843. Epub 2018 Aug 16.


NIH's ineffective funding policies.

Wahls WP.

Science. 2017 Jun 16;356(6343):1132-1133. doi: 10.1126/science.aan6504. No abstract available.


Nonsense codon suppression in fission yeast due to mutations of tRNA(Ser.11) and translation release factor Sup35 (eRF3).

Protacio RU, Storey AJ, Davidson MK, Wahls WP.

Curr Genet. 2015 May;61(2):165-73. doi: 10.1007/s00294-014-0465-7. Epub 2014 Dec 18.


A CRISPR-based approach for proteomic analysis of a single genomic locus.

Waldrip ZJ, Byrum SD, Storey AJ, Gao J, Byrd AK, Mackintosh SG, Wahls WP, Taverna SD, Raney KD, Tackett AJ.

Epigenetics. 2014 Sep;9(9):1207-11. doi: 10.4161/epi.29919. Epub 2014 Jul 18.


Binding of the transcription factor Atf1 to promoters serves as a barrier to phase nucleosome arrays and avoid cryptic transcription.

García P, Paulo E, Gao J, Wahls WP, Ayté J, Lowy E, Hidalgo E.

Nucleic Acids Res. 2014;42(16):10351-9. doi: 10.1093/nar/gku704. Epub 2014 Aug 13.


Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe.

Gao J, Kan F, Wagnon JL, Storey AJ, Protacio RU, Davidson MK, Wahls WP.

Curr Genet. 2014 May;60(2):109-19. doi: 10.1007/s00294-013-0406-x. Epub 2013 Sep 12.


A stress-activated, p38 mitogen-activated protein kinase-ATF/CREB pathway regulates posttranscriptional, sequence-dependent decay of target RNAs.

Gao J, Wagnon JL, Protacio RM, Glazko GV, Beggs M, Raj V, Davidson MK, Wahls WP.

Mol Cell Biol. 2013 Aug;33(15):3026-35. doi: 10.1128/MCB.00349-13. Epub 2013 Jun 3.


New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination.

Wahls WP, Davidson MK.

Nucleic Acids Res. 2012 Nov 1;40(20):9983-9. doi: 10.1093/nar/gks761. Epub 2012 Aug 16. Review.


DNA sequence-mediated, evolutionarily rapid redistribution of meiotic recombination hotspots.

Wahls WP, Davidson MK.

Genetics. 2011 Nov;189(3):685-94. doi: 10.1534/genetics.111.134130.


Meiotic recombination protein Rec12: functional conservation, crossover homeostasis and early crossover/non-crossover decision.

Kan F, Davidson MK, Wahls WP.

Nucleic Acids Res. 2011 Mar;39(4):1460-72. doi: 10.1093/nar/gkq993. Epub 2010 Oct 28.


Discrete DNA sites regulate global distribution of meiotic recombination.

Wahls WP, Davidson MK.

Trends Genet. 2010 May;26(5):202-8. doi: 10.1016/j.tig.2010.02.003. Epub 2010 Apr 8.


Phosphorylation-independent regulation of Atf1-promoted meiotic recombination by stress-activated, p38 kinase Spc1 of fission yeast.

Gao J, Davidson MK, Wahls WP.

PLoS One. 2009;4(5):e5533. doi: 10.1371/journal.pone.0005533. Epub 2009 May 14.


Meiotic recombination hotspots of fission yeast are directed to loci that express non-coding RNA.

Wahls WP, Siegel ER, Davidson MK.

PLoS One. 2008 Aug 6;3(8):e2887. doi: 10.1371/journal.pone.0002887.


Distinct regions of ATF/CREB proteins Atf1 and Pcr1 control recombination hotspot ade6-M26 and the osmotic stress response.

Gao J, Davidson MK, Wahls WP.

Nucleic Acids Res. 2008 May;36(9):2838-51. doi: 10.1093/nar/gkn037. Epub 2008 Mar 29.


Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast.

Wu H, Gao J, Sharif WD, Davidson MK, Wahls WP.

Protein Expr Purif. 2004 Nov;38(1):136-44.


Atf1-Pcr1-M26 complex links stress-activated MAPK and cAMP-dependent protein kinase pathways via chromatin remodeling of cgs2+.

Davidson MK, Shandilya HK, Hirota K, Ohta K, Wahls WP.

J Biol Chem. 2004 Dec 3;279(49):50857-63. Epub 2004 Sep 23.


Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.

Yamada T, Mizuno K, Hirota K, Kon N, Wahls WP, Hartsuiker E, Murofushi H, Shibata T, Ohta K.

EMBO J. 2004 Apr 21;23(8):1792-803. Epub 2004 Feb 26.


Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe.

Kon N, Krawchuk MD, Warren BG, Smith GR, Wahls WP.

Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13765-70.


Region-specific meiotic recombination in Schizosaccharomyces pombe: the rec11 gene.

Li YF, Numata M, Wahls WP, Smith GR.

Mol Microbiol. 1997 Mar;23(5):869-78.


Single-stranded DNA binding activity of C1-tetrahydrofolate synthase enzymes.

Wahls WP, Song JM, Smith GR.

J Biol Chem. 1993 Nov 15;268(32):23792-8.


Two hypervariable minisatellite DNA binding proteins.

Wahls WP, Swenson G, Moore PD.

Nucleic Acids Res. 1991 Jun 25;19(12):3269-74.


Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells.

Wahls WP, Wallace LJ, Moore PD.

Cell. 1990 Jan 12;60(1):95-103.


No runs, no drips, no errors: a new technique for sealing polyacrylamide gel electrophoresis apparatus.

Wahls WP, Kingzette M.

Biotechniques. 1988 Apr;6(4):308-9. No abstract available.


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