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Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis.

Huang KC, Wang ML, Chen SJ, Kuo JC, Wang WJ, Nhi Nguyen PN, Wahlin KJ, Lu JF, Tran AA, Shi M, Chien Y, Yarmishyn AA, Tsai PH, Yang TC, Jane WN, Chang CC, Peng CH, Schlaeger TM, Chiou SH.

Stem Cell Reports. 2019 Nov 12;13(5):906-923. doi: 10.1016/j.stemcr.2019.09.010. Epub 2019 Oct 24.


Improper study design precludes valid effect estimates in important suicide prevention research.

Thorell LH, Wahlin K, Ranstam J.

Int J Methods Psychiatr Res. 2019 Sep;28(3):e1786. doi: 10.1002/mpr.1786. Epub 2019 May 29.


Risk of Esophageal Adenocarcinoma After Antireflux Surgery in Patients With Gastroesophageal Reflux Disease in the Nordic Countries.

Maret-Ouda J, Wahlin K, Artama M, Brusselaers N, Färkkilä M, Lynge E, Mattsson F, Pukkala E, Romundstad P, Tryggvadóttir L, von Euler-Chelpin M, Lagergren J.

JAMA Oncol. 2018 Nov 1;4(11):1576-1582. doi: 10.1001/jamaoncol.2018.3054. Retraction in: JAMA Oncol. 2019 May 1;5(5):744-745.


Thyroid hormone signaling specifies cone subtypes in human retinal organoids.

Eldred KC, Hadyniak SE, Hussey KA, Brenerman B, Zhang PW, Chamling X, Sluch VM, Welsbie DS, Hattar S, Taylor J, Wahlin K, Zack DJ, Johnston RJ Jr.

Science. 2018 Oct 12;362(6411). pii: eaau6348. doi: 10.1126/science.aau6348.


Sex differences in the prognosis after surgery for esophageal squamous cell carcinoma and adenocarcinoma.

Kauppila JH, Wahlin K, Lagergren P, Lagergren J.

Int J Cancer. 2019 Mar 15;144(6):1284-1291. doi: 10.1002/ijc.31840. Epub 2018 Oct 31.


Global time trends in the incidence of esophageal squamous cell carcinoma.

Wang QL, Xie SH, Wahlin K, Lagergren J.

Clin Epidemiol. 2018 Jun 19;10:717-728. doi: 10.2147/CLEP.S166078. eCollection 2018.


University hospital status and surgeon volume and risk of reoperation following surgery for esophageal cancer.

Kauppila JH, Wahlin K, Lagergren P, Lagergren J.

Eur J Surg Oncol. 2018 May;44(5):632-637. doi: 10.1016/j.ejso.2018.02.212. Epub 2018 Mar 2.


Neoadjuvant therapy in relation to lymphadenectomy and resection margins during surgery for oesophageal cancer.

Kauppila JH, Wahlin K, Lagergren P, Lagergren J.

Sci Rep. 2018 Jan 11;8(1):446. doi: 10.1038/s41598-017-18879-6.


Time latencies of Helicobacter pylori eradication after peptic ulcer and risk of recurrent ulcer, ulcer adverse events, and gastric cancer: a population-based cohort study.

Sverdén E, Brusselaers N, Wahlin K, Lagergren J.

Gastrointest Endosc. 2018 Aug;88(2):242-250.e1. doi: 10.1016/j.gie.2017.11.035. Epub 2017 Dec 9.


Data Resource Profile: The Nordic Obesity Surgery Cohort (NordOSCo).

Tao W, Artama M, von Euler-Chelpin M, Konings P, Ljung R, Lynge E, Ólafsdóttir GH, Pukkala E, Romundstad P, Tryggvadottir L, Wahlin K, Lagergren J.

Int J Epidemiol. 2018 Feb 1;47(1):357. doi: 10.1093/ije/dyx256. No abstract available.


Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden.

Brusselaers N, Wahlin K, Engstrand L, Lagergren J.

BMJ Open. 2017 Oct 30;7(10):e017739. doi: 10.1136/bmjopen-2017-017739.


Data Resource Profile: The Nordic Obesity Surgery Cohort (NordOSCo).

Tao W, Artama M, von Euler-Chelpin M, Konings P, Ljung R, Lynge E, Ólafsdóttir GH, Pukkala E, Romundstad P, Tryggvadottir L, Wahlin K, Lagergren J.

Int J Epidemiol. 2017 Oct 1;46(5):1367-1367g. doi: 10.1093/ije/dyx199. No abstract available. Erratum in: Int J Epidemiol. 2018 Feb 1;47(1):357.


Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis.

Remez LA, Onishi A, Menuchin-Lasowski Y, Biran A, Blackshaw S, Wahlin KJ, Zack DJ, Ashery-Padan R.

Dev Biol. 2017 Dec 1;432(1):140-150. doi: 10.1016/j.ydbio.2017.09.030. Epub 2017 Oct 7.


Association Between Laparoscopic Antireflux Surgery and Recurrence of Gastroesophageal Reflux.

Maret-Ouda J, Wahlin K, El-Serag HB, Lagergren J.

JAMA. 2017 Sep 12;318(10):939-946. doi: 10.1001/jama.2017.10981.


Cause of death in patients diagnosed with esophageal cancer in Sweden: a population-based study.

Xie SH, Wahlin K, Lagergren J.

Oncotarget. 2017 Feb 11;8(31):51800-51809. doi: 10.18632/oncotarget.15270. eCollection 2017 Aug 1.


Three-dimensional automated reporter quantification (3D-ARQ) technology enables quantitative screening in retinal organoids.

Vergara MN, Flores-Bellver M, Aparicio-Domingo S, McNally M, Wahlin KJ, Saxena MT, Mumm JS, Canto-Soler MV.

Development. 2017 Oct 15;144(20):3698-3705. doi: 10.1242/dev.146290. Epub 2017 Sep 4.


Nordic registry-based cohort studies: Possibilities and pitfalls when combining Nordic registry data.

Maret-Ouda J, Tao W, Wahlin K, Lagergren J.

Scand J Public Health. 2017 Jul;45(17_suppl):14-19. doi: 10.1177/1403494817702336. Review.


Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo).

Maret-Ouda J, Wahlin K, Artama M, Brusselaers N, Färkkilä M, Lynge E, Mattsson F, Pukkala E, Romundstad P, Tryggvadóttir L, Euler-Chelpin MV, Lagergren J.

BMJ Open. 2017 Jun 8;7(6):e016505. doi: 10.1136/bmjopen-2017-016505.


A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery.

Wilson DR, Routkevitch D, Rui Y, Mosenia A, Wahlin KJ, Quinones-Hinojosa A, Zack DJ, Green JJ.

Mol Ther. 2017 Jul 5;25(7):1697-1709. doi: 10.1016/j.ymthe.2017.04.008. Epub 2017 May 4.


Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells.

Wahlin KJ, Maruotti JA, Sripathi SR, Ball J, Angueyra JM, Kim C, Grebe R, Li W, Jones BW, Zack DJ.

Sci Rep. 2017 Apr 10;7(1):766. doi: 10.1038/s41598-017-00774-9.


Cornea organoids from human induced pluripotent stem cells.

Foster JW, Wahlin K, Adams SM, Birk DE, Zack DJ, Chakravarti S.

Sci Rep. 2017 Jan 27;7:41286. doi: 10.1038/srep41286.


All-cause and cancer-specific mortality in GORD in a population-based cohort study (the HUNT study).

Ness-Jensen E, Gottlieb-Vedi E, Wahlin K, Lagergren J.

Gut. 2018 Feb;67(2):209-215. doi: 10.1136/gutjnl-2016-312514. Epub 2016 Oct 27.


Surgery during holiday periods and prognosis in oesophageal cancer: a population-based nationwide Swedish cohort study.

Markar SR, Wahlin K, Mattsson F, Lagergren P, Lagergren J.

BMJ Open. 2016 Sep 6;6(9):e013069. doi: 10.1136/bmjopen-2016-013069.


Haemochromatosis and gastrointestinal cancer.

Lagergren K, Wahlin K, Mattsson F, Alderson D, Lagergren J.

Int J Cancer. 2016 Oct 15;139(8):1740-3. doi: 10.1002/ijc.30229. Epub 2016 Jun 24.


University hospital status and prognosis following surgery for esophageal cancer.

Markar SR, Wahlin K, Lagergren P, Lagergren J.

Eur J Surg Oncol. 2016 Aug;42(8):1191-5. doi: 10.1016/j.ejso.2016.05.028. Epub 2016 Jun 1.


Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells.

Maruotti J, Sripathi SR, Bharti K, Fuller J, Wahlin KJ, Ranganathan V, Sluch VM, Berlinicke CA, Davis J, Kim C, Zhao L, Wan J, Qian J, Corneo B, Temple S, Dubey R, Olenyuk BZ, Bhutto I, Lutty GA, Zack DJ.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10950-5. doi: 10.1073/pnas.1422818112. Epub 2015 Aug 12.


Effect of oral diclofenac intake on faecal calprotectin.

Rendek Z, Falk M, Grodzinsky E, Wahlin K, Kechagias S, Svernlöv R, Hjortswang H.

Scand J Gastroenterol. 2016 Jan;51(1):28-32. doi: 10.3109/00365521.2015.1066421. Epub 2015 Jul 22.


Does quantitative lung SPECT detect lung abnormalities earlier than lung function tests? Results of a pilot study.

Norberg P, Persson HL, Schmekel B, Carlsson GA, Wahlin K, Sandborg M, Gustafsson A.

EJNMMI Res. 2014 Dec;4(1):39. doi: 10.1186/s13550-014-0039-1. Epub 2014 Aug 1.


Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs.

Ranganathan V, Wahlin K, Maruotti J, Zack DJ.

Nat Commun. 2014 Aug 8;5:4516. doi: 10.1038/ncomms5516.


A paradox in suicide statistics in estimating specificity of tests for suicide - reply to Mushquash and co-workers and Culver.

Thorell LH, Wolfersdorf M, Straub R, Steyer J, Hodgkinson S, Kaschka WP, Jandl M, Wahlin K.

J Psychiatr Res. 2014 Jul;54:142-3. doi: 10.1016/j.jpsychires.2014.03.015. Epub 2014 Mar 28. No abstract available.


Modeling retinal dystrophies using patient-derived induced pluripotent stem cells.

Wahlin KJ, Maruotti J, Zack DJ.

Adv Exp Med Biol. 2014;801:157-64. doi: 10.1007/978-1-4614-3209-8_20. Review.


Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium.

Masuda T, Wahlin K, Wan J, Hu J, Maruotti J, Yang X, Iacovelli J, Wolkow N, Kist R, Dunaief JL, Qian J, Zack DJ, Esumi N.

J Biol Chem. 2014 May 2;289(18):12908-21. doi: 10.1074/jbc.M114.556738. Epub 2014 Mar 14.


Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells.

Bhise NS, Wahlin KJ, Zack DJ, Green JJ.

Int J Nanomedicine. 2013;8:4641-58. doi: 10.2147/IJN.S53830. Epub 2013 Dec 4.


Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death.

Wahlin KJ, Enke RA, Fuller JA, Kalesnykas G, Zack DJ, Merbs SL.

PLoS One. 2013 Nov 11;8(11):e79140. doi: 10.1371/journal.pone.0079140. eCollection 2013.


A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells.

Maruotti J, Wahlin K, Gorrell D, Bhutto I, Lutty G, Zack DJ.

Stem Cells Transl Med. 2013 May;2(5):341-54. doi: 10.5966/sctm.2012-0106. Epub 2013 Apr 12.


Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.

Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16. doi: 10.1073/pnas.1212655110. Epub 2013 Jan 22.


Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina.

Wahlin KJ, Hackler L Jr, Adler R, Zack DJ.

J Comp Neurol. 2010 Dec 15;518(24):4938-62. doi: 10.1002/cne.22499.


Endogenous expression of ASLV viral proteins in specific pathogen free chicken embryos: relevance for the developmental biology research field.

McNally MM, Wahlin KJ, Canto-Soler MV.

BMC Dev Biol. 2010 Oct 18;10:106. doi: 10.1186/1471-213X-10-106.


Roadmap for assessing regional trends in groundwater quality.

Wahlin K, Grimvall A.

Environ Monit Assess. 2010 Jun;165(1-4):217-31. doi: 10.1007/s10661-009-0940-7. Epub 2009 May 12.


Comparison of non-viral methods to genetically modify and enrich populations of primary human corneal endothelial cells.

Engler C, Kelliher C, Wahlin KJ, Speck CL, Jun AS.

Mol Vis. 2009;15:629-37. Epub 2009 Apr 1.


Developmental regulation of muscleblind-like (MBNL) gene expression in the chicken embryo retina.

Huang H, Wahlin KJ, McNally M, Irving ND, Adler R.

Dev Dyn. 2008 Jan;237(1):286-96.


Molecular dynamics of photoreceptor synapse formation in the developing chick retina.

Wahlin KJ, Moreira EF, Huang H, Yu N, Adler R.

J Comp Neurol. 2008 Feb 10;506(5):822-37.


MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the rat.

Pasterkamp RJ, Dai HN, Terman JR, Wahlin KJ, Kim B, Bregman BS, Popovich PG, Kolodkin AL.

Mol Cell Neurosci. 2006 Jan;31(1):52-69. Epub 2005 Oct 17.


A method for analysis of gene expression in isolated mouse photoreceptor and Müller cells.

Wahlin KJ, Lim L, Grice EA, Campochiaro PA, Zack DJ, Adler R.

Mol Vis. 2004 Jun 3;10:366-75.


Intraocular adenoviral vector-mediated gene transfer in proliferative retinopathies.

Mori K, Gehlbach P, Ando A, Wahlin K, Gunther V, McVey D, Wei L, Campochiaro PA.

Invest Ophthalmol Vis Sci. 2002 May;43(5):1610-5.


Neurotrophic signaling in normal and degenerating rodent retinas.

Wahlin KJ, Adler R, Zack DJ, Campochiaro PA.

Exp Eye Res. 2001 Nov;73(5):693-701.


Angiopoietin 2 expression in the retina: upregulation during physiologic and pathologic neovascularization.

Hackett SF, Ozaki H, Strauss RW, Wahlin K, Suri C, Maisonpierre P, Yancopoulos G, Campochiaro PA.

J Cell Physiol. 2000 Sep;184(3):275-84. Review.


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