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Items: 10

1.

Mass balance, pharmacokinetics and metabolism of the selective S1P1 receptor modulator ponesimod in humans.

Reyes M, Hoch M, Brossard P, Wagner-Redeker W, Miraval T, Dingemanse J.

Xenobiotica. 2015 Feb;45(2):139-49. doi: 10.3109/00498254.2014.955832. Epub 2014 Sep 4.

PMID:
25188442
2.

Bioanalysis for plasma protein binding studies in drug discovery and drug development: views and recommendations of the European Bioanalysis Forum.

Buscher B, Laakso S, Mascher H, Pusecker K, Doig M, Dillen L, Wagner-Redeker W, Pfeifer T, Delrat P, Timmerman P.

Bioanalysis. 2014 Mar;6(5):673-82. doi: 10.4155/bio.13.338.

3.

Validation of an LC-MS/MS method for the quantitative determination of the orexin receptor antagonist almorexant and its four primary metabolites in human plasma.

Wagner-Redeker W, Finsterwald I, Dingemanse J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Mar 1;951-952:96-103. doi: 10.1016/j.jchromb.2014.01.033. Epub 2014 Jan 30.

PMID:
24531213
4.

Disposition and metabolism of setipiprant, a selective oral CRTH2 antagonist, in humans.

Hoch M, Wank J, Kluge I, Wagner-Redeker W, Dingemanse J.

Drugs R D. 2013 Dec;13(4):253-69. doi: 10.1007/s40268-013-0031-7.

5.

Elucidation of the metabolic pathways and the resulting multiple metabolites of almorexant, a dual orexin receptor antagonist, in humans.

Dingemanse J, Hoever P, Hoch M, Treiber A, Wagner-Redeker W, Miraval T, Hopfgartner G, Shakeri-Nejad K.

Drug Metab Dispos. 2013 May;41(5):1046-59. doi: 10.1124/dmd.112.050120. Epub 2013 Feb 21.

PMID:
23431113
6.

Validated LC-MS/MS method for the quantitative determination of the glucosylceramide synthase inhibitor miglustat in mouse plasma and human plasma and its application to a pharmacokinetic study.

Spieker E, Wagner-Redeker W, Dingemanse J.

J Pharm Biomed Anal. 2012 Feb 5;59:123-9. doi: 10.1016/j.jpba.2011.10.016. Epub 2011 Oct 20.

PMID:
22079117
7.

Simultaneous determination of capecitabine and its metabolite 5-fluorouracil by column switching and liquid chromatographic/tandem mass spectrometry.

Siethoff C, Orth M, Ortling A, Brendel E, Wagner-Redeker W.

J Mass Spectrom. 2004 Aug;39(8):884-9.

PMID:
15329840
8.

Proteomics application exercise of the Swiss Proteomics Society: report of the SPS'02 session.

Binz PA, Abdi F, Affolter M, Allard L, Barblan J, Bhardwaj S, Bienvenut WV, Bulet P, Burgess J, Carrette O, Corthals G, Delalande F, Diemer H, Favreau P, Giuliano E, Gueguen Y, Guillaume E, Hahner S, Man P, Michalet S, Neri D, Noukakis D, Palagi P, Paroutaud P, Pimenta DC, Quadroni M, Resemann A, Richert S, Rybak J, Sanchez JC, Scherl A, Scheurer S, Schweiger Hufnagel U, Siethoff C, Suckau D, van Dorsselaer A, Wagner Redeker W, Walter N, Stöcklin R.

Proteomics. 2003 Aug;3(8):1562-6.

PMID:
12923782
9.

Separation and characterisation of bovine histone H1 subtypes by combined ion-exchange and reversed-phase chromatography and mass spectrometry.

Berger RG, Hoffmann R, Zeppezauer M, Wagner-Redeker W, Maljers L, Ingendoh A, Hillenkamp F.

J Chromatogr A. 1995 Sep 8;711(1):159-65.

PMID:
7496487
10.

Chemical phosphorylation of the peptides GGXA (X = S, T, Y): an evaluation of different chemical approaches.

Hoffmann R, Wachs WO, Berger RG, Kalbitzer HR, Waidelich D, Bayer E, Wagner-Redeker W, Zeppezauer M.

Int J Pept Protein Res. 1995 Jan;45(1):26-34.

PMID:
7775006

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