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Items: 1 to 50 of 83

1.

The Preparation of Decellularized Mouse Lung Matrix Scaffolds for Analysis of Lung Regenerative Cell Potential.

Bölükbas DA, De Santis MM, Alsafadi HN, Doryab A, Wagner DE.

Methods Mol Biol. 2019;1940:275-295. doi: 10.1007/978-1-4939-9086-3_20.

PMID:
30788833
2.

Freedom From Chew: Using Social Branding to Reduce Chewing Tobacco Use Among Country Peer Crowd Teens.

Wagner DE, Fernandez P, Jordan JW, Saggese DJ.

Health Educ Behav. 2018 Oct 24:1090198118806966. doi: 10.1177/1090198118806966. [Epub ahead of print]

PMID:
30353748
3.

Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.

Lehmann M, Buhl L, Alsafadi HN, Klee S, Hermann S, Mutze K, Ota C, Lindner M, Behr J, Hilgendorff A, Wagner DE, Königshoff M.

Respir Res. 2018 Sep 15;19(1):175. doi: 10.1186/s12931-018-0876-y.

4.

Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis.

Ota C, Ng-Blichfeldt JP, Korfei M, Alsafadi HN, Lehmann M, Skronska-Wasek W, M De Santis M, Guenther A, Wagner DE, Königshoff M.

Sci Rep. 2018 Aug 28;8(1):12983. doi: 10.1038/s41598-018-31214-x.

5.

Increased Extracellular Vesicles Mediate WNT-5A Signaling in Idiopathic Pulmonary Fibrosis.

Martin-Medina A, Lehmann M, Burgy O, Hermann S, Baarsma HA, Wagner DE, De Santis MM, Ciolek F, Hofer TP, Frankenberger M, Aichler M, Lindner M, Gesierich W, Guenther A, Walch A, Coughlan C, Wolters P, Lee JS, Behr J, Königshoff M.

Am J Respir Crit Care Med. 2018 Jul 25. doi: 10.1164/rccm.201708-1580OC. [Epub ahead of print]

PMID:
30044642
6.

Avian lungs: A novel scaffold for lung bioengineering.

Wrenn SM, Griswold ED, Uhl FE, Uriarte JJ, Park HE, Coffey AL, Dearborn JS, Ahlers BA, Deng B, Lam YW, Huston DR, Lee PC, Wagner DE, Weiss DJ.

PLoS One. 2018 Jun 27;13(6):e0198956. doi: 10.1371/journal.pone.0198956. eCollection 2018.

7.

Co-opting of ClinicalTrials.gov by patient-funded studies.

Wagner DE, Turner L, Panoskaltsis-Mortari A, Weiss DJ, Ikonomou L.

Lancet Respir Med. 2018 Aug;6(8):579-581. doi: 10.1016/S2213-2600(18)30242-X. Epub 2018 Jun 19. No abstract available.

PMID:
29934051
8.

Clonal Analysis of Planarian Stem Cells by Subtotal Irradiation and Single-Cell Transplantation.

Wang IE, Wagner DE, Reddien PW.

Methods Mol Biol. 2018;1774:479-495. doi: 10.1007/978-1-4939-7802-1_20.

PMID:
29916173
9.

How to build a lung: latest advances and emerging themes in lung bioengineering.

De Santis MM, Bölükbas DA, Lindstedt S, Wagner DE.

Eur Respir J. 2018 Jul 27;52(1). pii: 1601355. doi: 10.1183/13993003.01355-2016. Print 2018 Jul.

PMID:
29903859
10.

Acellular human lung scaffolds to model lung disease and tissue regeneration.

Gilpin SE, Wagner DE.

Eur Respir Rev. 2018 Jun 6;27(148). pii: 180021. doi: 10.1183/16000617.0021-2018. Print 2018 Jun 30. Review.

11.

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo.

Wagner DE, Weinreb C, Collins ZM, Briggs JA, Megason SG, Klein AM.

Science. 2018 Jun 1;360(6392):981-987. doi: 10.1126/science.aar4362. Epub 2018 Apr 26.

12.

The dynamics of gene expression in vertebrate embryogenesis at single-cell resolution.

Briggs JA, Weinreb C, Wagner DE, Megason S, Peshkin L, Kirschner MW, Klein AM.

Science. 2018 Jun 1;360(6392). pii: eaar5780. doi: 10.1126/science.aar5780. Epub 2018 Apr 26.

13.

Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain.

Raj B, Wagner DE, McKenna A, Pandey S, Klein AM, Shendure J, Gagnon JA, Schier AF.

Nat Biotechnol. 2018 Jun;36(5):442-450. doi: 10.1038/nbt.4103. Epub 2018 Mar 28.

14.

Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring.

Jiang D, Correa-Gallegos D, Christ S, Stefanska A, Liu J, Ramesh P, Rajendran V, De Santis MM, Wagner DE, Rinkevich Y.

Nat Cell Biol. 2018 Apr;20(4):422-431. doi: 10.1038/s41556-018-0073-8. Epub 2018 Mar 28.

PMID:
29593327
15.

The Hip Hop peer crowd: An opportunity for intervention to reduce tobacco use among at-risk youth.

Walker MW, Navarro MA, Hoffman L, Wagner DE, Stalgaitis CA, Jordan JW.

Addict Behav. 2018 Jul;82:28-34. doi: 10.1016/j.addbeh.2018.02.014. Epub 2018 Feb 10.

16.

TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH2-terminal kinase-1-dependent manner.

van der Velden JL, Wagner DE, Lahue KG, Abdalla ST, Lam YW, Weiss DJ, Janssen-Heininger YMW.

Am J Physiol Lung Cell Mol Physiol. 2018 Jun 1;314(6):L984-L997. doi: 10.1152/ajplung.00053.2017. Epub 2018 Feb 22.

PMID:
29469614
17.

Human Pulmonary 3D Models For Translational Research.

Zscheppang K, Berg J, Hedtrich S, Verheyen L, Wagner DE, Suttorp N, Hippenstiel S, Hocke AC.

Biotechnol J. 2018 Jan;13(1). doi: 10.1002/biot.201700341. Epub 2017 Sep 20. Review.

PMID:
28865134
18.

Preparation of Decellularized Lung Matrices for Cell Culture and Protein Analysis.

Uhl FE, Wagner DE, Weiss DJ.

Methods Mol Biol. 2017;1627:253-283. doi: 10.1007/978-1-4939-7113-8_18.

PMID:
28836208
19.

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.

Lehmann M, Korfei M, Mutze K, Klee S, Skronska-Wasek W, Alsafadi HN, Ota C, Costa R, Schiller HB, Lindner M, Wagner DE, Günther A, Königshoff M.

Eur Respir J. 2017 Aug 3;50(2). pii: 1602367. doi: 10.1183/13993003.02367-2016. Print 2017 Aug.

20.

Unproven Stem Cell Treatments for Lung Disease-An Emerging Public Health Problem.

Ikonomou L, Panoskaltsis-Mortari A, Wagner DE, Freishtat RJ, Weiss DJ; American Thoracic Society Respiratory Cell and Molecular Biology Assembly Stem Cell Working Group.

Am J Respir Crit Care Med. 2017 Apr 1;195(7):P13-P14. doi: 10.1164/rccm.1957P13. No abstract available.

PMID:
28362195
21.

An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices.

Alsafadi HN, Staab-Weijnitz CA, Lehmann M, Lindner M, Peschel B, Königshoff M, Wagner DE.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L896-L902. doi: 10.1152/ajplung.00084.2017. Epub 2017 Mar 17.

22.

Genetic screening enters the single-cell era.

Wagner DE, Klein AM.

Nat Methods. 2017 Feb 28;14(3):237-238. doi: 10.1038/nmeth.4196. No abstract available.

PMID:
28245215
23.

Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.

Skronska-Wasek W, Mutze K, Baarsma HA, Bracke KR, Alsafadi HN, Lehmann M, Costa R, Stornaiuolo M, Novellino E, Brusselle GG, Wagner DE, Yildirim AÖ, Königshoff M.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):172-185. doi: 10.1164/rccm.201605-0904OC.

PMID:
28245136
24.

Why Peer Crowds Matter: Incorporating Youth Subcultures and Values in Health Education Campaigns.

Moran MB, Walker MW, Alexander TN, Jordan JW, Wagner DE.

Am J Public Health. 2017 Mar;107(3):389-395. doi: 10.2105/AJPH.2016.303595. Epub 2017 Jan 19.

25.

Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

Baarsma HA, Skronska-Wasek W, Mutze K, Ciolek F, Wagner DE, John-Schuster G, Heinzelmann K, Günther A, Bracke KR, Dagouassat M, Boczkowski J, Brusselle GG, Smits R, Eickelberg O, Yildirim AÖ, Königshoff M.

J Exp Med. 2017 Feb;214(2):565. doi: 10.1084/jem.2016067501052017c. Epub 2017 Jan 9. No abstract available.

26.

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

Baarsma HA, Skronska-Wasek W, Mutze K, Ciolek F, Wagner DE, John-Schuster G, Heinzelmann K, Günther A, Bracke KR, Dagouassat M, Boczkowski J, Brusselle GG, Smits R, Eickelberg O, Yildirim AÖ, Königshoff M.

J Exp Med. 2017 Jan;214(1):143-163. doi: 10.1084/jem.20160675. Epub 2016 Dec 15. Erratum in: J Exp Med. 2017 Feb;214(2):565.

27.

Linking bronchopulmonary dysplasia to adult chronic lung diseases: role of WNT signaling.

Ota C, Baarsma HA, Wagner DE, Hilgendorff A, Königshoff M.

Mol Cell Pediatr. 2016 Dec;3(1):34. Epub 2016 Oct 7. Review.

28.

An Official American Thoracic Society Workshop Report 2015. Stem Cells and Cell Therapies in Lung Biology and Diseases.

Wagner DE, Cardoso WV, Gilpin SE, Majka S, Ott H, Randell SH, Thébaud B, Waddell T, Weiss DJ; ATS Subcommittee on Stem Cells and Cell Therapies.

Ann Am Thorac Soc. 2016 Aug;13(8):S259-78. doi: 10.1513/AnnalsATS.201606-466ST.

PMID:
27509163
29.

The Global Emergence of Unregulated Stem Cell Treatments for Respiratory Diseases. Professional Societies Need to Act.

Ikonomou L, Freishtat RJ, Wagner DE, Panoskaltsis-Mortari A, Weiss DJ.

Ann Am Thorac Soc. 2016 Aug;13(8):1205-7. doi: 10.1513/AnnalsATS.201604-277ED. No abstract available.

PMID:
27509147
30.

Comparative Decellularization and Recellularization of Wild-Type and Alpha 1,3 Galactosyltransferase Knockout Pig Lungs: A Model for Ex Vivo Xenogeneic Lung Bioengineering and Transplantation.

Platz J, Bonenfant NR, Uhl FE, Coffey AL, McKnight T, Parsons C, Sokocevic D, Borg ZD, Lam YW, Deng B, Fields JG, DeSarno M, Loi R, Hoffman AM, Bianchi J, Dacken B, Petersen T, Wagner DE, Weiss DJ.

Tissue Eng Part C Methods. 2016 Aug;22(8):725-39. doi: 10.1089/ten.TEC.2016.0109. Epub 2016 Jul 14.

31.

Decreased Laminin Expression by Human Lung Epithelial Cells and Fibroblasts Cultured in Acellular Lung Scaffolds from Aged Mice.

Godin LM, Sandri BJ, Wagner DE, Meyer CM, Price AP, Akinnola I, Weiss DJ, Panoskaltsis-Mortari A.

PLoS One. 2016 Mar 8;11(3):e0150966. doi: 10.1371/journal.pone.0150966. eCollection 2016.

32.

CD11b+ and Sca-1+ Cells Exert the Main Beneficial Effects of Systemically Administered Bone Marrow-Derived Mononuclear Cells in a Murine Model of Mixed Th2/Th17 Allergic Airway Inflammation.

Cruz FF, Borg ZD, Goodwin M, Coffey AL, Wagner DE, Rocco PR, Weiss DJ.

Stem Cells Transl Med. 2016 Apr;5(4):488-99. doi: 10.5966/sctm.2015-0141. Epub 2016 Mar 1.

33.

Residual Detergent Detection Method for Nondestructive Cytocompatibility Evaluation of Decellularized Whole Lung Scaffolds.

Zvarova B, Uhl FE, Uriarte JJ, Borg ZD, Coffey AL, Bonenfant NR, Weiss DJ, Wagner DE.

Tissue Eng Part C Methods. 2016 May;22(5):418-28. doi: 10.1089/ten.TEC.2015.0439. Epub 2016 Mar 29.

34.

WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts.

Klee S, Lehmann M, Wagner DE, Baarsma HA, Königshoff M.

Sci Rep. 2016 Feb 12;6:20547. doi: 10.1038/srep20547.

35.

Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease.

Kammerl IE, Dann A, Mossina A, Brech D, Lukas C, Vosyka O, Nathan P, Conlon TM, Wagner DE, Overkleeft HS, Prasse A, Rosas IO, Straub T, Krauss-Etschmann S, Königshoff M, Preissler G, Winter H, Lindner M, Hatz R, Behr J, Heinzelmann K, Yildirim AÖ, Noessner E, Eickelberg O, Meiners S.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1230-41. doi: 10.1164/rccm.201506-1122OC.

PMID:
26756824
36.

Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice.

Cruz FF, Borg ZD, Goodwin M, Sokocevic D, Wagner DE, Coffey A, Antunes M, Robinson KL, Mitsialis SA, Kourembanas S, Thane K, Hoffman AM, McKenna DH, Rocco PR, Weiss DJ.

Stem Cells Transl Med. 2015 Nov;4(11):1302-16. doi: 10.5966/sctm.2014-0280. Epub 2015 Sep 16.

37.

Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures.

Uhl FE, Vierkotten S, Wagner DE, Burgstaller G, Costa R, Koch I, Lindner M, Meiners S, Eickelberg O, Königshoff M.

Eur Respir J. 2015 Oct;46(4):1150-66. doi: 10.1183/09031936.00183214. Epub 2015 Apr 30.

38.

An official American Thoracic Society workshop report: stem cells and cell therapies in lung biology and diseases.

Weiss DJ, Chambers D, Giangreco A, Keating A, Kotton D, Lelkes PI, Wagner DE, Prockop DJ; ATS Subcommittee on Stem Cells and Cell Therapies.

Ann Am Thorac Soc. 2015 Apr;12(4):S79-97. doi: 10.1513/AnnalsATS.201502-086ST.

39.

Design and Synthesis of an Artificial Pulmonary Pleura for High Throughput Studies in Acellular Human Lungs.

Wagner DE, Fenn SL, Bonenfant NR, Marks ER, Borg Z, Saunders P, Oldinski RA, Weiss DJ.

Cell Mol Bioeng. 2014 Jun;7(2):184-195.

40.

teashirt is required for head-versus-tail regeneration polarity in planarians.

Owen JH, Wagner DE, Chen CC, Petersen CP, Reddien PW.

Development. 2015 Mar 15;142(6):1062-72. doi: 10.1242/dev.119685. Epub 2015 Feb 27.

41.

Single-cell analysis reveals functionally distinct classes within the planarian stem cell compartment.

van Wolfswinkel JC, Wagner DE, Reddien PW.

Cell Stem Cell. 2014 Sep 4;15(3):326-339. doi: 10.1016/j.stem.2014.06.007. Epub 2014 Jul 10.

42.

Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis.

Lau AN, Curtis SJ, Fillmore CM, Rowbotham SP, Mohseni M, Wagner DE, Beede AM, Montoro DT, Sinkevicius KW, Walton ZE, Barrios J, Weiss DJ, Camargo FD, Wong KK, Kim CF.

EMBO J. 2014 Mar 3;33(5):468-81. doi: 10.1002/embj.201386082. Epub 2014 Feb 4. Erratum in: EMBO J. 2014 Jul 1;33(13):1502.

43.

Comparative decellularization and recellularization of normal versus emphysematous human lungs.

Wagner DE, Bonenfant NR, Parsons CS, Sokocevic D, Brooks EM, Borg ZD, Lathrop MJ, Wallis JD, Daly AB, Lam YW, Deng B, DeSarno MJ, Ashikaga T, Loi R, Weiss DJ.

Biomaterials. 2014 Mar;35(10):3281-97. doi: 10.1016/j.biomaterials.2013.12.103. Epub 2014 Jan 22.

44.

Three-dimensional scaffolds of acellular human and porcine lungs for high throughput studies of lung disease and regeneration.

Wagner DE, Bonenfant NR, Sokocevic D, DeSarno MJ, Borg ZD, Parsons CS, Brooks EM, Platz JJ, Khalpey ZI, Hoganson DM, Deng B, Lam YW, Oldinski RA, Ashikaga T, Weiss DJ.

Biomaterials. 2014 Mar;35(9):2664-79. doi: 10.1016/j.biomaterials.2013.11.078. Epub 2014 Jan 8.

45.

Muscle cells provide instructions for planarian regeneration.

Witchley JN, Mayer M, Wagner DE, Owen JH, Reddien PW.

Cell Rep. 2013 Aug 29;4(4):633-41. doi: 10.1016/j.celrep.2013.07.022. Epub 2013 Aug 15.

46.

Cytocompatibility evaluation of microwave sintered biphasic calcium phosphate scaffolds synthesized using pH control.

Wagner DE, Jones AD, Zhou H, Bhaduri SB.

Mater Sci Eng C Mater Biol Appl. 2013 Apr 1;33(3):1710-9. doi: 10.1016/j.msec.2012.12.084. Epub 2012 Dec 31.

PMID:
23827628
47.

A microwave-assisted solution combustion synthesis to produce europium-doped calcium phosphate nanowhiskers for bioimaging applications.

Wagner DE, Eisenmann KM, Nestor-Kalinoski AL, Bhaduri SB.

Acta Biomater. 2013 Sep;9(9):8422-32. doi: 10.1016/j.actbio.2013.05.033. Epub 2013 Jun 11.

PMID:
23764803
48.

The Housing First Model (HFM) fidelity index: designing and testing a tool for measuring integrity of housing programs that serve active substance users.

Watson DP, Orwat J, Wagner DE, Shuman V, Tolliver R.

Subst Abuse Treat Prev Policy. 2013 May 3;8:16. doi: 10.1186/1747-597X-8-16.

49.

Can stem cells be used to generate new lungs? Ex vivo lung bioengineering with decellularized whole lung scaffolds.

Wagner DE, Bonvillain RW, Jensen T, Girard ED, Bunnell BA, Finck CM, Hoffman AM, Weiss DJ.

Respirology. 2013 Aug;18(6):895-911. doi: 10.1111/resp.12102. Review.

50.

The effect of age and emphysematous and fibrotic injury on the re-cellularization of de-cellularized lungs.

Sokocevic D, Bonenfant NR, Wagner DE, Borg ZD, Lathrop MJ, Lam YW, Deng B, Desarno MJ, Ashikaga T, Loi R, Hoffman AM, Weiss DJ.

Biomaterials. 2013 Apr;34(13):3256-69. doi: 10.1016/j.biomaterials.2013.01.028. Epub 2013 Feb 4.

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