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Items: 1 to 50 of 295

1.

Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.

Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2018 Aug 3;3(26). pii: eaao4747. doi: 10.1126/sciimmunol.aao4747.

PMID:
30076281
2.

Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging.

Wong SL, Wagner DD.

FASEB J. 2018 Jun 20:fj201800691R. doi: 10.1096/fj.201800691R. [Epub ahead of print]

PMID:
29924943
3.

Neuroimaging, neuromodulation, and population health: the neuroscience of chronic disease prevention.

Hall PA, Bickel WK, Erickson KI, Wagner DD.

Ann N Y Acad Sci. 2018 Jun 4. doi: 10.1111/nyas.13868. [Epub ahead of print] Review.

PMID:
29863790
4.

Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms.

Wolach O, Sellar RS, Martinod K, Cherpokova D, McConkey M, Chappell RJ, Silver AJ, Adams D, Castellano CA, Schneider RK, Padera RF, DeAngelo DJ, Wadleigh M, Steensma DP, Galinsky I, Stone RM, Genovese G, McCarroll SA, Iliadou B, Hultman C, Neuberg D, Mullally A, Wagner DD, Ebert BL.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaan8292. doi: 10.1126/scitranslmed.aan8292.

PMID:
29643232
5.

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice.

Zitomersky NL, Demers M, Martinod K, Gallant M, Cifuni SM, Biswas A, Snapper S, Wagner DD.

TH Open. 2017 Jun;1(1):e11-e23. doi: 10.1055/s-0037-1603927.

6.

Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice.

Witsch T, Martinod K, Sorvillo N, Portier I, De Meyer SF, Wagner DD.

J Am Heart Assoc. 2018 Jan 24;7(3). pii: e007004. doi: 10.1161/JAHA.117.007004.

7.

Citrullinated histone H3, a biomarker of neutrophil extracellular trap formation, predicts the risk of venous thromboembolism in cancer patients.

Mauracher LM, Posch F, Martinod K, Grilz E, Däullary T, Hell L, Brostjan C, Zielinski C, Ay C, Wagner DD, Pabinger I, Thaler J.

J Thromb Haemost. 2018 Mar;16(3):508-518. doi: 10.1111/jth.13951. Epub 2018 Feb 7.

PMID:
29325226
8.

Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice.

Hayashi H, Cherpokova D, Martinod K, Witsch T, Wong SL, Gallant M, Cifuni SM, Guarente LP, Wagner DD.

PLoS One. 2017 Dec 13;12(12):e0188341. doi: 10.1371/journal.pone.0188341. eCollection 2017.

9.

A key role for Rac and Pak signaling in neutrophil extracellular traps (NETs) formation defines a new potential therapeutic target.

Gavillet M, Martinod K, Renella R, Wagner DD, Williams DA.

Am J Hematol. 2018 Feb;93(2):269-276. doi: 10.1002/ajh.24970. Epub 2017 Dec 6.

PMID:
29124783
10.

Unraveling Vascular Inflammation: From Immunology to Imaging.

Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN.

J Am Coll Cardiol. 2017 Sep 12;70(11):1403-1412. doi: 10.1016/j.jacc.2017.07.750. Review.

11.

Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice.

Ponomaryov T, Payne H, Fabritz L, Wagner DD, Brill A.

Circ Res. 2017 Sep 29;121(8):941-950. doi: 10.1161/CIRCRESAHA.117.311185. Epub 2017 Jul 24.

12.

Peptidylarginine deiminase 4 promotes age-related organ fibrosis.

Martinod K, Witsch T, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, Gallant M, Mauler M, Cifuni SM, Wagner DD.

J Exp Med. 2017 Feb;214(2):439-458. doi: 10.1084/jem.20160530. Epub 2016 Dec 28.

13.

PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model.

Erpenbeck L, Chowdhury CS, Zsengellér ZK, Gallant M, Burke SD, Cifuni S, Hahn S, Wagner DD, Karumanchi SA.

Biol Reprod. 2016 Dec;95(6):132. doi: 10.1095/biolreprod.116.140293. Epub 2016 Nov 9.

14.

Neural Population Decoding Reveals the Intrinsic Positivity of the Self.

Chavez RS, Heatherton TF, Wagner DD.

Cereb Cortex. 2017 Nov 1;27(11):5222-5229. doi: 10.1093/cercor/bhw302.

PMID:
27664966
15.

Priming of neutrophils toward NETosis promotes tumor growth.

Demers M, Wong SL, Martinod K, Gallant M, Cabral JE, Wang Y, Wagner DD.

Oncoimmunology. 2016 Feb 18;5(5):e1134073. doi: 10.1080/2162402X.2015.1134073. eCollection 2016 May.

16.

The Dorsal Medial Prefrontal Cortex Responds Preferentially to Social Interactions during Natural Viewing.

Wagner DD, Kelley WM, Haxby JV, Heatherton TF.

J Neurosci. 2016 Jun 29;36(26):6917-25. doi: 10.1523/JNEUROSCI.4220-15.2016.

17.

Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice.

Shaw MA, Kombrinck KW, McElhinney KE, Sweet DR, Flick MJ, Palumbo JS, Cheng M, Esmon NL, Esmon CT, Brill A, Wagner DD, Degen JL, Mullins ES.

Blood. 2016 Aug 4;128(5):721-31. doi: 10.1182/blood-2015-11-680280. Epub 2016 Jun 1.

18.

OC-16 - Neutrophil extracellular traps and tissue factor-bearing microvesicles: a liaison dangereuse causing overt DIC in cancer patients?

Hell L, Thaler J, Martinod K, Ay C, Posch F, Wagner DD, Pabinger I.

Thromb Res. 2016 Apr;140 Suppl 1:S174-5. doi: 10.1016/S0049-3848(16)30133-5. Epub 2016 Apr 8.

PMID:
27161688
19.

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease.

Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A.

Science. 2016 Apr 22;352(6284):463-6. doi: 10.1126/science.aaf3926.

20.

NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation.

Thålin C, Demers M, Blomgren B, Wong SL, von Arbin M, von Heijne A, Laska AC, Wallén H, Wagner DD, Aspberg S.

Thromb Res. 2016 Mar;139:56-64. doi: 10.1016/j.thromres.2016.01.009. Epub 2016 Jan 12.

21.

Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis.

Martinod K, Witsch T, Farley K, Gallant M, Remold-O'Donnell E, Wagner DD.

J Thromb Haemost. 2016 Mar;14(3):551-8. doi: 10.1111/jth.13239. Epub 2016 Feb 5.

22.

Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples.

Gavillet M, Martinod K, Renella R, Harris C, Shapiro NI, Wagner DD, Williams DA.

Am J Hematol. 2015 Dec;90(12):1155-8. doi: 10.1002/ajh.24185. Epub 2015 Oct 6.

23.

ACTIVITY IN CORTICAL MIDLINE STRUCTURES IS MODULATED BY SELF-CONSTRUAL CHANGES DURING ACCULTURATION.

Chen PA, Wagner DD, Kelley WM, Heatherton TF.

Cult Brain. 2015 Mar;3(1):39-52.

24.

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing.

Wong SL, Demers M, Martinod K, Gallant M, Wang Y, Goldfine AB, Kahn CR, Wagner DD.

Nat Med. 2015 Jul;21(7):815-9. doi: 10.1038/nm.3887. Epub 2015 Jun 15.

25.

ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor-Induced Thrombotic Microangiopathy.

Erpenbeck L, Demers M, Zsengellér ZK, Gallant M, Cifuni SM, Stillman IE, Karumanchi SA, Wagner DD.

J Am Soc Nephrol. 2016 Jan;27(1):120-31. doi: 10.1681/ASN.2014121165. Epub 2015 Jun 2.

26.

P-selectin promotes neutrophil extracellular trap formation in mice.

Etulain J, Martinod K, Wong SL, Cifuni SM, Schattner M, Wagner DD.

Blood. 2015 Jul 9;126(2):242-6. doi: 10.1182/blood-2015-01-624023. Epub 2015 May 15.

27.

Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the incidence of deep vein thrombosis in mice.

Thomas GM, Brill A, Mezouar S, Crescence L, Gallant M, Dubois C, Wagner DD.

J Thromb Haemost. 2015 Jul;13(7):1310-9. doi: 10.1111/jth.13002. Epub 2015 Jun 8.

28.

In search of a human self-regulation system.

Kelley WM, Wagner DD, Heatherton TF.

Annu Rev Neurosci. 2015 Jul 8;38:389-411. doi: 10.1146/annurev-neuro-071013-014243. Epub 2015 Apr 30. Review.

29.

PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock.

Martinod K, Fuchs TA, Zitomersky NL, Wong SL, Demers M, Gallant M, Wang Y, Wagner DD.

Blood. 2015 Mar 19;125(12):1948-56. doi: 10.1182/blood-2014-07-587709. Epub 2015 Jan 26.

30.

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, Lind KE, Locke K, Maller C, Martinod K, Patten C, Polyakova O, Rise CE, Rüdiger M, Sheppard RJ, Slade DJ, Thomas P, Thorpe J, Yao G, Drewes G, Wagner DD, Thompson PR, Prinjha RK, Wilson DM.

Nat Chem Biol. 2015 Mar;11(3):189-91. doi: 10.1038/nchembio.1735. Epub 2015 Jan 26.

31.

Dietary omega-3 alpha-linolenic acid does not prevent venous thrombosis in mice.

Reiner MF, Martinod K, Stivala S, Savarese G, Camici GG, Lüscher TF, Wagner DD, Beer JH.

Thromb Haemost. 2015 Jan;113(1):177-84. doi: 10.1160/TH14-03-0200. Epub 2014 Sep 18.

PMID:
25231375
32.

Neural predictors of giving in to temptation in daily life.

Lopez RB, Hofmann W, Wagner DD, Kelley WM, Heatherton TF.

Psychol Sci. 2014 Jul;25(7):1337-44. doi: 10.1177/0956797614531492. Epub 2014 Apr 30.

33.

Neutrophil extracellular traps form predominantly during the organizing stage of human venous thromboembolism development.

Savchenko AS, Martinod K, Seidman MA, Wong SL, Borissoff JI, Piazza G, Libby P, Goldhaber SZ, Mitchell RN, Wagner DD.

J Thromb Haemost. 2014 Jun;12(6):860-70. doi: 10.1111/jth.12571.

34.

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease.

Chen G, Zhang D, Fuchs TA, Manwani D, Wagner DD, Frenette PS.

Blood. 2014 Jun 12;123(24):3818-27. doi: 10.1182/blood-2013-10-529982. Epub 2014 Mar 11.

35.

NETosis: a new factor in tumor progression and cancer-associated thrombosis.

Demers M, Wagner DD.

Semin Thromb Hemost. 2014 Apr;40(3):277-83. doi: 10.1055/s-0034-1370765. Epub 2014 Mar 3. Review.

36.

Thrombosis: tangled up in NETs.

Martinod K, Wagner DD.

Blood. 2014 May 1;123(18):2768-76. doi: 10.1182/blood-2013-10-463646. Epub 2013 Dec 23. Review.

37.

Identification and environmental distribution of dcpA, which encodes the reductive dehalogenase catalyzing the dichloroelimination of 1,2-dichloropropane to propene in organohalide-respiring chloroflexi.

Padilla-Crespo E, Yan J, Swift C, Wagner DD, Chourey K, Hettich RL, Ritalahti KM, Löffler FE.

Appl Environ Microbiol. 2014 Feb;80(3):808-18. doi: 10.1128/AEM.02927-13. Epub 2013 Nov 15.

38.

VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice.

Savchenko AS, Borissoff JI, Martinod K, De Meyer SF, Gallant M, Erpenbeck L, Brill A, Wang Y, Wagner DD.

Blood. 2014 Jan 2;123(1):141-8. doi: 10.1182/blood-2013-07-514992. Epub 2013 Nov 7.

39.

Plasma DNA is Elevated in Patients with Deep Vein Thrombosis.

Diaz JA, Fuchs TA, Jackson TO, Kremer Hovinga JA, Lämmle B, Henke PK, Myers DD Jr, Wagner DD, Wakefield TW; for the Michigan Research Venous Group*.

J Vasc Surg Venous Lymphat Disord. 2013 Oct 1;1(4). doi: 10.1016/j.jvsv.2012.12.002.

40.

Self-regulatory depletion enhances neural responses to rewards and impairs top-down control.

Wagner DD, Altman M, Boswell RG, Kelley WM, Heatherton TF.

Psychol Sci. 2013 Nov 1;24(11):2262-71. doi: 10.1177/0956797613492985. Epub 2013 Sep 11.

41.

Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice.

Suidan GL, Brill A, De Meyer SF, Voorhees JR, Cifuni SM, Cabral JE, Wagner DD.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2112-20. doi: 10.1161/ATVBAHA.113.301362. Epub 2013 Jul 3.

42.

Elevated levels of circulating DNA and chromatin are independently associated with severe coronary atherosclerosis and a prothrombotic state.

Borissoff JI, Joosen IA, Versteylen MO, Brill A, Fuchs TA, Savchenko AS, Gallant M, Martinod K, Ten Cate H, Hofstra L, Crijns HJ, Wagner DD, Kietselaer BLJH.

Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):2032-2040. doi: 10.1161/ATVBAHA.113.301627. Epub 2013 Jul 1.

43.

Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice.

Brill A, Suidan GL, Wagner DD.

J Thromb Haemost. 2013 Sep;11(9):1773-5. doi: 10.1111/jth.12310. No abstract available.

44.

The wonderful world of gas detection.

Wagner DD.

Occup Health Saf. 2013 Apr;82(4):60-1. No abstract available.

PMID:
23729155
45.

Retrospective analysis of Salmonella, Campylobacter, Escherichia coli, and Enterococcus in animal feed ingredients.

Ge B, LaFon PC, Carter PJ, McDermott SD, Abbott J, Glenn A, Ayers SL, Friedman SL, Paige JC, Wagner DD, Zhao S, McDermott PF, Rasmussen MA.

Foodborne Pathog Dis. 2013 Aug;10(8):684-91. doi: 10.1089/fpd.2012.1470. Epub 2013 May 21.

PMID:
23692074
46.

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice.

Martinod K, Demers M, Fuchs TA, Wong SL, Brill A, Gallant M, Hu J, Wang Y, Wagner DD.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8674-9. doi: 10.1073/pnas.1301059110. Epub 2013 May 6.

47.

Neutrophils release extracellular DNA traps during storage of red blood cell units.

Fuchs TA, Alvarez JJ, Martinod K, Bhandari AA, Kaufman RM, Wagner DD.

Transfusion. 2013 Dec;53(12):3210-6. doi: 10.1111/trf.12203. Epub 2013 Apr 8.

49.

Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities.

Suidan GL, Duerschmied D, Dillon GM, Vanderhorst V, Hampton TG, Wong SL, Voorhees JR, Wagner DD.

PLoS One. 2013;8(3):e59032. doi: 10.1371/journal.pone.0059032. Epub 2013 Mar 14. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/49097405-57c1-4923-875a-9216de91d230.

50.

Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.

Duerschmied D, Suidan GL, Demers M, Herr N, Carbo C, Brill A, Cifuni SM, Mauler M, Cicko S, Bader M, Idzko M, Bode C, Wagner DD.

Blood. 2013 Feb 7;121(6):1008-15. doi: 10.1182/blood-2012-06-437392. Epub 2012 Dec 12.

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