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Items: 1 to 50 of 129

1.

A Portable Electrospinner for Nanofiber Synthesis and Its Application for Cosmetic Treatment of Alopecia.

Revia RA, Wagner BA, Zhang M.

Nanomaterials (Basel). 2019 Sep 14;9(9). pii: E1317. doi: 10.3390/nano9091317.

2.

Metadherin enhances vulnerability of cancer cells to ferroptosis.

Bi J, Yang S, Li L, Dai Q, Borcherding N, Wagner BA, Buettner GR, Spitz DR, Leslie KK, Zhang J, Meng X.

Cell Death Dis. 2019 Sep 17;10(10):682. doi: 10.1038/s41419-019-1897-2.

3.

First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma.

Allen BG, Bodeker KL, Smith MC, Monga V, Sandhu S, Hohl R, Carlisle T, Brown H, Hollenbeck N, Vollstedt S, Greenlee JD, Howard MA, Mapuskar KA, Seyedin SN, Caster JM, Jones KA, Cullen JJ, Berg D, Wagner BA, Buettner GR, TenNapel MJ, Smith BJ, Spitz DR, Buatti JM.

Clin Cancer Res. 2019 Aug 19. doi: 10.1158/1078-0432.CCR-19-0594. [Epub ahead of print]

PMID:
31427282
4.

Association of bruxism and anxiety symptoms among military firefighters with frequent episodic tension type headache and temporomandibular disorders.

Wagner BA, Moreira Filho PF, Bernardo VG.

Arq Neuropsiquiatr. 2019 Jul 29;77(7):478-484. doi: 10.1590/0004-282X20190069.

5.

Pharmacologic Ascorbate Primes Pancreatic Cancer Cells for Death by Rewiring Cellular Energetics and Inducing DNA Damage.

Buranasudja V, Doskey CM, Gibson AR, Wagner BA, Du J, Gordon DJ, Koppenhafer SL, Cullen JJ, Buettner GR.

Mol Cancer Res. 2019 Oct;17(10):2102-2114. doi: 10.1158/1541-7786.MCR-19-0381. Epub 2019 Jul 23.

PMID:
31337671
6.

Assessment of the Stability of Supraphysiological Ascorbate in Human Blood: Appropriate Handling of Samples from Clinical Trials for Measurements of Pharmacological Ascorbate.

Petronek MS, Wagner BA, Hollenbeck NJ, Caster JM, Spitz DR, Cullen JJ, Buettner GR, Allen BG.

Radiat Res. 2019 Jun;191(6):491-496. doi: 10.1667/RR15328.1. Epub 2019 Apr 30.

PMID:
31039080
7.

Nox2 NADPH oxidase is dispensable for platelet activation or arterial thrombosis in mice.

Sonkar VK, Kumar R, Jensen M, Wagner BA, Sharathkumar AA, Miller FJ Jr, Fasano M, Lentz SR, Buettner GR, Dayal S.

Blood Adv. 2019 Apr 23;3(8):1272-1284. doi: 10.1182/bloodadvances.2018025569.

8.

Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells.

Lafin JT, Sarsour EH, Kalen AL, Wagner BA, Buettner GR, Goswami PC.

Int J Mol Sci. 2019 Jan 8;20(1). pii: E225. doi: 10.3390/ijms20010225.

9.

Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer.

Alexander MS, O'Leary BR, Wilkes JG, Gibson AR, Wagner BA, Du J, Sarsour E, Hwang RF, Buettner GR, Cullen JJ.

Radiat Res. 2019 Jan;191(1):43-51. doi: 10.1667/RR15189.1. Epub 2018 Oct 30.

PMID:
30376411
10.

Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer.

Alexander MS, Wilkes JG, Schroeder SR, Buettner GR, Wagner BA, Du J, Gibson-Corley K, O'Leary BR, Spitz DR, Buatti JM, Berg DJ, Bodeker KL, Vollstedt S, Brown HA, Allen BG, Cullen JJ.

Cancer Res. 2018 Dec 15;78(24):6838-6851. doi: 10.1158/0008-5472.CAN-18-1680. Epub 2018 Sep 25.

12.

Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface.

Wert KJ, Velez G, Cross MR, Wagner BA, Teoh-Fitzgerald ML, Buettner GR, McAnany JJ, Olivier A, Tsang SH, Harper MM, Domann FE, Bassuk AG, Mahajan VB.

Free Radic Biol Med. 2018 Aug 20;124:408-419. doi: 10.1016/j.freeradbiomed.2018.06.024. Epub 2018 Jun 22.

13.

Corrigendum to: Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells [Redox Biol. (2018) 82-87].

Brandt KE, Falls KC, Schoenfeld JD, Rodman SN 3rd, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA.

Redox Biol. 2018 Jun 8:100935. doi: 10.1016/j.redox.2018.06.001. [Epub ahead of print] No abstract available.

14.

Effects of testosterone dose on spatial memory among castrated adult male rats.

Wagner BA, Braddick VC, Batson CG, Cullen BH, Miller LE, Spritzer MD.

Psychoneuroendocrinology. 2018 Mar;89:120-130. doi: 10.1016/j.psyneuen.2017.12.025. Epub 2017 Dec 29.

15.

Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner.

Heer CD, Davis AB, Riffe DB, Wagner BA, Falls KC, Allen BG, Buettner GR, Beardsley RA, Riley DP, Spitz DR.

Antioxidants (Basel). 2018 Jan 19;7(1). pii: E18. doi: 10.3390/antiox7010018.

16.

Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models.

Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Bradley MD, Wagner BA, Buettner GR, Monga V, Milhem M, Spitz DR, Allen BG.

Redox Biol. 2018 Apr;14:417-422. doi: 10.1016/j.redox.2017.09.012. Epub 2017 Sep 28.

17.

Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells.

Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA.

Redox Biol. 2018 Apr;14:82-87. doi: 10.1016/j.redox.2017.08.017. Epub 2017 Aug 26. Erratum in: Redox Biol. 2018 Jun 8;:.

18.

O2⋅- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate.

Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, Monga V, Bodeker KL, Ahmann L, Vollstedt S, Brown H, Kauffman EPS, Schall ME, Hohl RJ, Clamon GH, Greenlee JD, Howard MA, Schultz MK, Smith BJ, Riley DP, Domann FE, Cullen JJ, Buettner GR, Buatti JM, Spitz DR, Allen BG.

Cancer Cell. 2017 Aug 14;32(2):268. doi: 10.1016/j.ccell.2017.07.008. No abstract available.

19.

Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging.

Son JM, Sarsour EH, Kakkerla Balaraju A, Fussell J, Kalen AL, Wagner BA, Buettner GR, Goswami PC.

Aging Cell. 2017 Oct;16(5):1136-1145. doi: 10.1111/acel.12649. Epub 2017 Jul 31.

20.

Seasonal and sex differences in cell proliferation, neurogenesis, and cell death within the dentate gyrus of adult wild-caught meadow voles.

Spritzer MD, Panning AW, Engelman SM, Prince WT, Casler AE, Georgakas JE, Jaeger ECB, Nelson LR, Roy EA, Wagner BA.

Neuroscience. 2017 Sep 30;360:155-165. doi: 10.1016/j.neuroscience.2017.07.046. Epub 2017 Jul 28.

PMID:
28757249
21.

O2⋅- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate.

Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, Monga V, Bodeker KL, Ahmann L, Vollstedt S, Brown H, Shanahan Kauffman EP, Schall ME, Hohl RJ, Clamon GH, Greenlee JD, Howard MA, Schultz MK, Smith BJ, Riley DP, Domann FE, Cullen JJ, Buettner GR, Buatti JM, Spitz DR, Allen BG.

Cancer Cell. 2017 Apr 10;31(4):487-500.e8. doi: 10.1016/j.ccell.2017.02.018. Epub 2017 Mar 30. Erratum in: Cancer Cell. 2017 Aug 14;32(2):268.

22.

Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy.

Doskey CM, Buranasudja V, Wagner BA, Wilkes JG, Du J, Cullen JJ, Buettner GR.

Redox Biol. 2016 Dec;10:274-284. doi: 10.1016/j.redox.2016.10.010. Epub 2016 Oct 28.

24.

Direct spectrophotometric measurement of supra-physiological levels of ascorbate in plasma.

Witmer JR, Wetherell BJ, Wagner BA, Du J, Cullen JJ, Buettner GR.

Redox Biol. 2016 Aug;8:298-304. doi: 10.1016/j.redox.2016.02.004. Epub 2016 Feb 13.

25.

Comparison of mixed effects models of antimicrobial resistance metrics of livestock and poultry Salmonella isolates from a national monitoring system.

Bjork KE, Kopral CA, Wagner BA, Dargatz DA.

Prev Vet Med. 2015 Dec 1;122(3):265-72. doi: 10.1016/j.prevetmed.2015.10.010. Epub 2015 Nov 6.

PMID:
26597093
26.

Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture.

Doskey CM, van 't Erve TJ, Wagner BA, Buettner GR.

PLoS One. 2015 Jul 14;10(7):e0132572. doi: 10.1371/journal.pone.0132572. eCollection 2015.

27.

Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart.

Rasmussen TP, Wu Y, Joiner ML, Koval OM, Wilson NR, Luczak ED, Wang Q, Chen B, Gao Z, Zhu Z, Wagner BA, Soto J, McCormick ML, Kutschke W, Weiss RM, Yu L, Boudreau RL, Abel ED, Zhan F, Spitz DR, Buettner GR, Song LS, Zingman LV, Anderson ME.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9129-34. doi: 10.1073/pnas.1504705112. Epub 2015 Jul 7.

28.

Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer.

Du J, Cieslak JA 3rd, Welsh JL, Sibenaller ZA, Allen BG, Wagner BA, Kalen AL, Doskey CM, Strother RK, Button AM, Mott SL, Smith B, Tsai S, Mezhir J, Goswami PC, Spitz DR, Buettner GR, Cullen JJ.

Cancer Res. 2015 Aug 15;75(16):3314-26. doi: 10.1158/0008-5472.CAN-14-1707. Epub 2015 Jun 16.

29.

Role of labile iron in the toxicity of pharmacological ascorbate.

Du J, Wagner BA, Buettner GR, Cullen JJ.

Free Radic Biol Med. 2015 Jul;84:289-295. doi: 10.1016/j.freeradbiomed.2015.03.033. Epub 2015 Apr 7.

30.

Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer.

Cieslak JA, Strother RK, Rawal M, Du J, Doskey CM, Schroeder SR, Button A, Wagner BA, Buettner GR, Cullen JJ.

Free Radic Biol Med. 2015 Jun;83:227-37. doi: 10.1016/j.freeradbiomed.2015.02.018. Epub 2015 Feb 26.

31.

The heritability of hemolysis in stored human red blood cells.

Van 't Erve TJ, Wagner BA, Martin SM, Knudson CM, Blendowski R, Keaton M, Holt T, Hess JR, Buettner GR, Ryckman KK, Darbro BW, Murray JC, Raife TJ.

Transfusion. 2015 Jun;55(6):1178-85. doi: 10.1111/trf.12992. Epub 2015 Feb 2.

32.

Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma.

O'Leary BR, Fath MA, Bellizzi AM, Hrabe JE, Button AM, Allen BG, Case AJ, Altekruse S, Wagner BA, Buettner GR, Lynch CF, Hernandez BY, Cozen W, Beardsley RA, Keene J, Henry MD, Domann FE, Spitz DR, Mezhir JJ.

Clin Cancer Res. 2015 Apr 1;21(7):1741-51. doi: 10.1158/1078-0432.CCR-14-1959. Epub 2015 Jan 29.

33.

Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes.

Xiao W, Sarsour EH, Wagner BA, Doskey CM, Buettner GR, Domann FE, Goswami PC.

Arch Toxicol. 2016 Feb;90(2):319-32. doi: 10.1007/s00204-014-1407-3. Epub 2014 Nov 23.

34.

SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.

Ozden O, Park SH, Wagner BA, Song HY, Zhu Y, Vassilopoulos A, Jung B, Buettner GR, Gius D.

Free Radic Biol Med. 2014 Nov;76:163-172. doi: 10.1016/j.freeradbiomed.2014.08.001. Epub 2014 Aug 22.

35.

Heritability of glutathione and related metabolites in stored red blood cells.

van 't Erve TJ, Doskey CM, Wagner BA, Hess JR, Darbro BW, Ryckman KK, Murray JC, Raife TJ, Buettner GR.

Free Radic Biol Med. 2014 Nov;76:107-13. doi: 10.1016/j.freeradbiomed.2014.07.040. Epub 2014 Aug 7.

36.

The heritability of metabolite concentrations in stored human red blood cells.

van 't Erve TJ, Wagner BA, Martin SM, Knudson CM, Blendowski R, Keaton M, Holt T, Hess JR, Buettner GR, Ryckman KK, Darbro BW, Murray JC, Raife TJ.

Transfusion. 2014 Aug;54(8):2055-63. doi: 10.1111/trf.12605. Epub 2014 Mar 6.

37.

Pharmacological ascorbate and ionizing radiation (IR) increase labile iron in pancreatic cancer.

Moser JC, Rawal M, Wagner BA, Du J, Cullen JJ, Buettner GR.

Redox Biol. 2013 Nov 26;2:22-7. doi: 10.1016/j.redox.2013.11.005. eCollection 2013.

38.

The concentration of glutathione in human erythrocytes is a heritable trait.

van 't Erve TJ, Wagner BA, Ryckman KK, Raife TJ, Buettner GR.

Free Radic Biol Med. 2013 Dec;65:742-749. doi: 10.1016/j.freeradbiomed.2013.08.002. Epub 2013 Aug 9.

39.

An Assay for the Rate of Removal of Extracellular Hydrogen Peroxide by Cells.

Wagner BA, Witmer JR, van 't Erve TJ, Buettner GR.

Redox Biol. 2013;1(1):210-217.

40.

CaMKII is essential for the proasthmatic effects of oxidation.

Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, Dworski R, Sammut D, Wagner BA, Buettner GR, Pope RM, Miller FJ Jr, Dibbern ME, Haitchi HM, Mohler PJ, Howarth PH, Zabner J, Kline JN, Grumbach IM, Anderson ME.

Sci Transl Med. 2013 Jul 24;5(195):195ra97. doi: 10.1126/scitranslmed.3006135.

41.

Manganoporphyrins increase ascorbate-induced cytotoxicity by enhancing H2O2 generation.

Rawal M, Schroeder SR, Wagner BA, Cushing CM, Welsh JL, Button AM, Du J, Sibenaller ZA, Buettner GR, Cullen JJ.

Cancer Res. 2013 Aug 15;73(16):5232-41. doi: 10.1158/0008-5472.CAN-13-0470. Epub 2013 Jun 13.

42.

Management practices associated with the rate of respiratory tract disease among preweaned beef calves in cow-calf operations in the United States.

Hanzlicek GA, Renter DR, White BJ, Wagner BA, Dargatz DA, Sanderson MW, Scott HM, Larson RE.

J Am Vet Med Assoc. 2013 May 1;242(9):1271-8. doi: 10.2460/javma.242.9.1271.

PMID:
23600786
43.

Testosterone influences spatial strategy preferences among adult male rats.

Spritzer MD, Fox EC, Larsen GD, Batson CG, Wagner BA, Maher J.

Horm Behav. 2013 May;63(5):800-12. doi: 10.1016/j.yhbeh.2013.03.018. Epub 2013 Apr 15.

44.

Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial.

Welsh JL, Wagner BA, van't Erve TJ, Zehr PS, Berg DJ, Halfdanarson TR, Yee NS, Bodeker KL, Du J, Roberts LJ 2nd, Drisko J, Levine M, Buettner GR, Cullen JJ.

Cancer Chemother Pharmacol. 2013 Mar;71(3):765-75. doi: 10.1007/s00280-013-2070-8. Epub 2013 Feb 5.

45.

Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity.

Olney KE, Du J, van 't Erve TJ, Witmer JR, Sibenaller ZA, Wagner BA, Buettner GR, Cullen JJ.

Free Radic Res. 2013 Mar;47(3):154-63. doi: 10.3109/10715762.2012.755263. Epub 2013 Jan 9.

46.

Herd-level prevalence of Mycobacterium avium subsp. paratuberculosis infection in United States dairy herds in 2007.

Lombard JE, Gardner IA, Jafarzadeh SR, Fossler CP, Harris B, Capsel RT, Wagner BA, Johnson WO.

Prev Vet Med. 2013 Feb 1;108(2-3):234-8. doi: 10.1016/j.prevetmed.2012.08.006. Epub 2012 Sep 12.

PMID:
22979969
47.

Comparison of individual, pooled, and composite fecal sampling methods for detection of Salmonella on U.S. dairy operations.

Lombard JE, Beam AL, Nifong EM, Fossler CP, Kopral CA, Dargatz DA, Wagner BA, Erdman MM, Fedorka-Cray PJ.

J Food Prot. 2012 Sep;75(9):1562-71. doi: 10.4315/0362-028X.JFP-12-012.

PMID:
22947462
48.

Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase.

Brown CO, Salem K, Wagner BA, Bera S, Singh N, Tiwari A, Choudhury A, Buettner GR, Goel A.

Biochem J. 2012 Jun 15;444(3):515-27. doi: 10.1042/BJ20112019.

49.

Regulation of pancreatic cancer growth by superoxide.

Du J, Nelson ES, Simons AL, Olney KE, Moser JC, Schrock HE, Wagner BA, Buettner GR, Smith BJ, Teoh ML, Tsao MS, Cullen JJ.

Mol Carcinog. 2013 Jul;52(7):555-67. doi: 10.1002/mc.21891. Epub 2012 Mar 5.

50.

Quantitative redox biology: an approach to understand the role of reactive species in defining the cellular redox environment.

Buettner GR, Wagner BA, Rodgers VG.

Cell Biochem Biophys. 2013 Nov;67(2):477-83. doi: 10.1007/s12013-011-9320-3. Review.

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