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Items: 1 to 50 of 192

1.

Effect of Doxorubicin Plus Olaratumab vs Doxorubicin Plus Placebo on Survival in Patients With Advanced Soft Tissue Sarcomas: The ANNOUNCE Randomized Clinical Trial.

Tap WD, Wagner AJ, Schöffski P, Martin-Broto J, Krarup-Hansen A, Ganjoo KN, Yen CC, Abdul Razak AR, Spira A, Kawai A, Le Cesne A, Van Tine BA, Naito Y, Park SH, Fedenko A, Pápai Z, Soldatenkova V, Shahir A, Mo G, Wright J, Jones RL; ANNOUNCE Investigators.

JAMA. 2020 Apr 7;323(13):1266-1276. doi: 10.1001/jama.2020.1707.

PMID:
32259228
2.

Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Safety and Clinical Activity in Patients With Advanced Chondrosarcoma.

Tap WD, Villalobos VM, Cote GM, Burris H, Janku F, Mir O, Beeram M, Wagner AJ, Jiang L, Wu B, Choe S, Yen K, Gliser C, Fan B, Agresta S, Pandya SS, Trent JC.

J Clin Oncol. 2020 Mar 24:JCO1902492. doi: 10.1200/JCO.19.02492. [Epub ahead of print]

PMID:
32208957
3.

Multicomponent flow on curved surfaces: A vielbein lattice Boltzmann approach.

Ambruş VE, Busuioc S, Wagner AJ, Paillusson F, Kusumaatmaja H.

Phys Rev E. 2019 Dec;100(6-1):063306. doi: 10.1103/PhysRevE.100.063306.

PMID:
31962535
4.

A phase II multi-strata study of lurbinectedin as a single agent or in combination with conventional chemotherapy in metastatic and/or unresectable sarcomas.

Cote GM, Choy E, Chen T, Marino-Enriquez A, Morgan J, Merriam P, Thornton K, Wagner AJ, Nathenson MJ, Demetri G, George S.

Eur J Cancer. 2020 Feb;126:21-32. doi: 10.1016/j.ejca.2019.10.021. Epub 2019 Dec 31.

PMID:
31896519
5.

Population Pharmacokinetics of Glasdegib in Patients With Advanced Hematologic Malignancies and Solid Tumors.

Lin S, Shaik N, Martinelli G, Wagner AJ, Cortes J, Ruiz-Garcia A.

J Clin Pharmacol. 2019 Nov 25. doi: 10.1002/jcph.1556. [Epub ahead of print]

PMID:
31769065
6.

Comparative outcomes of right versus left congenital diaphragmatic hernia: A multicenter analysis.

Abramov A, Fan W, Hernan R, Zenilman AL, Wynn J, Aspelund G, Khlevner J, Krishnan U, Lim FY, Mychaliska GB, Warner BW, Cusick R, Crombleholme T, Chung D, Danko ME, Wagner AJ, Azarow K, Schindel D, Potoka D, Soffer S, Fisher J, McCulley D, Farkouh-Karoleski C, Chung WK, Duron V.

J Pediatr Surg. 2020 Jan;55(1):33-38. doi: 10.1016/j.jpedsurg.2019.09.046. Epub 2019 Oct 26.

PMID:
31677822
7.

Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network.

Frezza AM, Assi T, Lo Vullo S, Ben-Ami E, Dufresne A, Yonemori K, Noguchi E, Siontis B, Ferraro R, Teterycz P, Duffaud F, Ravi V, Vincenzi B, Gelderblom H, Pantaleo MA, Baldi GG, Desar I, Fedenko A, Maki RG, Jones RL, Benjamin RS, Blay JY, Kawai A, Gounder M, Gronchi A, Le Cesne A, Mir O, Czarnecka AM, Schuetze S, Wagner AJ, Adam J, Barisella M, Sbaraglia M, Hornick JL, Meurgey A, Mariani L, Casali PG, Thornton K, Stacchiotti S.

Cancer. 2020 Jan 1;126(1):98-104. doi: 10.1002/cncr.32508. Epub 2019 Sep 19.

PMID:
31536651
8.

Phase I Study of Rapid Alternation of Sunitinib and Regorafenib for the Treatment of Tyrosine Kinase Inhibitor Refractory Gastrointestinal Stromal Tumors.

Serrano C, Leal A, Kuang Y, Morgan JA, Barysauskas CM, Phallen J, Triplett O, Mariño-Enríquez A, Wagner AJ, Demetri GD, Velculescu VE, Paweletz CP, Fletcher JA, George S.

Clin Cancer Res. 2019 Dec 15;25(24):7287-7293. doi: 10.1158/1078-0432.CCR-19-2150. Epub 2019 Aug 30.

PMID:
31471313
9.

Ex utero intrapartum treatment (EXIT) procedures.

Bence CM, Wagner AJ.

Semin Pediatr Surg. 2019 Aug;28(4):150820. doi: 10.1053/j.sempedsurg.2019.07.003. Epub 2019 Jul 22.

PMID:
31451172
10.

Phase 1 study of the MDM2 inhibitor AMG 232 in patients with advanced P53 wild-type solid tumors or multiple myeloma.

Gluck WL, Gounder MM, Frank R, Eskens F, Blay JY, Cassier PA, Soria JC, Chawla S, de Weger V, Wagner AJ, Siegel D, De Vos F, Rasmussen E, Henary HA.

Invest New Drugs. 2019 Jul 29. doi: 10.1007/s10637-019-00840-1. [Epub ahead of print]

PMID:
31359240
11.

Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial.

Tap WD, Gelderblom H, Palmerini E, Desai J, Bauer S, Blay JY, Alcindor T, Ganjoo K, Martín-Broto J, Ryan CW, Thomas DM, Peterfy C, Healey JH, van de Sande M, Gelhorn HL, Shuster DE, Wang Q, Yver A, Hsu HH, Lin PS, Tong-Starksen S, Stacchiotti S, Wagner AJ; ENLIVEN investigators.

Lancet. 2019 Aug 10;394(10197):478-487. doi: 10.1016/S0140-6736(19)30764-0. Epub 2019 Jun 19.

PMID:
31229240
12.

Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma.

Amin-Mansour A, George S, Sioletic S, Carter SL, Rosenberg M, Taylor-Weiner A, Stewart C, Chevalier A, Seepo S, Tracy A, Getz G, Hornick JL, Nucci MR, Quade B, Demetri GD, Raut CP, Garraway LA, Van Allen EM, Wagner AJ.

Clin Cancer Res. 2019 Aug 15;25(16):5135-5142. doi: 10.1158/1078-0432.CCR-19-0271. Epub 2019 Jun 4.

PMID:
31164371
13.

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor.

Thomson DW, Poeckel D, Zinn N, Rau C, Strohmer K, Wagner AJ, Graves AP, Perrin J, Bantscheff M, Duempelfeld B, Kasparcova V, Ramanjulu JM, Pesiridis GS, Muelbaier M, Bergamini G.

ACS Med Chem Lett. 2019 Mar 11;10(5):780-785. doi: 10.1021/acsmedchemlett.9b00027. eCollection 2019 May 9.

PMID:
31097999
14.

A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas.

Jones RL, Chawla SP, Attia S, Schöffski P, Gelderblom H, Chmielowski B, Le Cesne A, Van Tine BA, Trent JC, Patel S, Wagner AJ, Chugh R, Heyburn JW, Weil SC, Wang W, Viele K, Maki RG.

Cancer. 2019 Jul 15;125(14):2445-2454. doi: 10.1002/cncr.32084. Epub 2019 Apr 29.

15.

Subsequent pregnancy outcomes after open maternal-fetal surgery for myelomeningocele.

Goodnight WH, Bahtiyar O, Bennett KA, Emery SP, Lillegard JB, Fisher A, Goldstein R, Jatres J, Lim FY, McCullough L, Moehrlen U, Moldenhauer JS, Moon-Grady AJ, Ruano R, Skupski DW, Thom E, Treadwell MC, Tsao K, Wagner AJ, Waqar LN, Zaretsky M; fMMC Consortium sponsored by NAFTNet.

Am J Obstet Gynecol. 2019 May;220(5):494.e1-494.e7. doi: 10.1016/j.ajog.2019.03.008. Epub 2019 Mar 15.

PMID:
30885769
16.

Dynamic discriminant model for predicting respiratory distress at birth based on mass volume ratio in fetuses with congenital lung malformation.

Eyerly-Webb S, Nicolas CT, Watson D, Dion E, Amin R, Wagner AJ, Lampland A, Bendel-Stenzel E, Macardle CA, Kunisaki SM, Jorgenson A, Lillegard J, Feltis B.

Ultrasound Obstet Gynecol. 2019 Dec;54(6):759-766. doi: 10.1002/uog.20255. Epub 2019 Nov 12.

PMID:
30834623
17.

Characteristics of mismatch repair deficiency in sarcomas.

Doyle LA, Nowak JA, Nathenson MJ, Thornton K, Wagner AJ, Johnson JM, Albrayak A, George S, Sholl LM.

Mod Pathol. 2019 Jul;32(7):977-987. doi: 10.1038/s41379-019-0202-3. Epub 2019 Feb 14.

PMID:
30765880
18.

Clinical characteristics and treatment outcomes in six cases of malignant tenosynovial giant cell tumor: initial experience of molecularly targeted therapy.

Nakayama R, Jagannathan JP, Ramaiya N, Ferrone ML, Raut CP, Ready JE, Hornick JL, Wagner AJ.

BMC Cancer. 2018 Dec 29;18(1):1296. doi: 10.1186/s12885-018-5188-6.

19.

De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders.

Qi H, Yu L, Zhou X, Wynn J, Zhao H, Guo Y, Zhu N, Kitaygorodsky A, Hernan R, Aspelund G, Lim FY, Crombleholme T, Cusick R, Azarow K, Danko ME, Chung D, Warner BW, Mychaliska GB, Potoka D, Wagner AJ, ElFiky M, Wilson JM, Nickerson D, Bamshad M, High FA, Longoni M, Donahoe PK, Chung WK, Shen Y.

PLoS Genet. 2018 Dec 10;14(12):e1007822. doi: 10.1371/journal.pgen.1007822. eCollection 2018 Dec.

20.

Perceptions of Oncologists About Sharing Clinic Notes with Patients.

McCleary NJ, Healey MJ, Weng S, Song AB, Lederman RI, Ramelson HZ, Wagner AJ, Abel GA.

Oncologist. 2019 Jan;24(1):e46-e48. doi: 10.1634/theoncologist.2018-0070. Epub 2018 Sep 25.

21.

[Advance Care Planning (ACP). A Systematic Review of ACP Behavior by Women and Men in Germany].

Bondio MG, Wagner AJM, Krieger R, Weiß L, Kinnebrock S.

Gesundheitswesen. 2018 Jul 31. doi: 10.1055/a-0652-5556. [Epub ahead of print] German.

PMID:
30064152
22.

Effect of the Synthetic Bile Salt Analog CamSA on the Hamster Model of Clostridium difficile Infection.

Howerton A, Seymour CO, Murugapiran SK, Liao Z, Phan JR, Estrada A, Wagner AJ, Mefferd CC, Hedlund BP, Abel-Santos E.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e02251-17. doi: 10.1128/AAC.02251-17. Print 2018 Oct.

23.

Implementation to Optimization: A Tailored, Data-Driven Approach to Improve Provider Efficiency and Confidence in Use of the Electronic Medical Record.

Kadish SS, Mayer EL, Jackman DM, Pomerantz M, Brady L, Dimitriadis A, Cleveland JLF, Wagner AJ.

J Oncol Pract. 2018 Jul;14(7):e421-e428. doi: 10.1200/JOP.18.00093. Epub 2018 Jun 25.

PMID:
29939808
24.

Low Levels of Evidence for Neoadjuvant Chemotherapy to Treat Soft-Tissue Sarcoma.

George S, Wagner AJ.

JAMA Oncol. 2018 Sep 1;4(9):1169-1170. doi: 10.1001/jamaoncol.2018.1403. No abstract available.

PMID:
29879275
25.

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma.

McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM, Araujo DM, Wang WL, Tsai JW, Yeagley M, Wagner AJ, Futreal PA, Khan J, Lazar AJ, Kadoch C.

Cancer Cell. 2018 Jun 11;33(6):1128-1141.e7. doi: 10.1016/j.ccell.2018.05.002. Epub 2018 May 31.

26.

Meconium-stained amniotic fluid as a predictor of poor outcomes in gastroschisis.

Koehler SM, Loichinger M, Peterson E, Christensen M, Szabo A, Wagner AJ.

J Pediatr Surg. 2018 Sep;53(9):1665-1668. doi: 10.1016/j.jpedsurg.2018.04.023. Epub 2018 Apr 27.

PMID:
29803305
27.

Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series.

Frezza AM, Jones RL, Lo Vullo S, Asano N, Lucibello F, Ben-Ami E, Ratan R, Teterycz P, Boye K, Brahmi M, Palmerini E, Fedenko A, Vincenzi B, Brunello A, Desar IME, Benjamin RS, Blay JY, Broto JM, Casali PG, Gelderblom H, Grignani G, Gronchi A, Hall KS, Mir O, Rutkowski P, Wagner AJ, Anurova O, Collini P, Dei Tos AP, Flucke U, Hornick JL, Lobmaier I, Philippe T, Picci P, Ranchere D, Renne SL, Sbaraglia M, Thway K, Wagrodzki M, Wang WL, Yoshida A, Mariani L, Kawai A, Stacchiotti S.

JAMA Oncol. 2018 Sep 1;4(9):e180219. doi: 10.1001/jamaoncol.2018.0219. Epub 2018 Sep 13.

28.

National Practice Patterns for Prenatal Monitoring in Gastroschisis: Gastroschisis Outcomes of Delivery (GOOD) Provider Survey.

Amin R, Domack A, Bartoletti J, Peterson E, Rink B, Bruggink J, Christensen M, Johnson A, Polzin W, Wagner AJ.

Fetal Diagn Ther. 2019;45(2):125-130. doi: 10.1159/000487541. Epub 2018 May 23. Review.

PMID:
29791899
29.

Is isomerism a risk factor for intestinal volvulus?

Landisch RM, Loomba RS, Salazar JH, Buelow MW, Frommelt M, Anderson RH, Wagner AJ.

J Pediatr Surg. 2018 Jun;53(6):1118-1122. doi: 10.1016/j.jpedsurg.2018.02.071. Epub 2018 Mar 6.

PMID:
29605269
30.

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.

Savitski MM, Zinn N, Faelth-Savitski M, Poeckel D, Gade S, Becher I, Muelbaier M, Wagner AJ, Strohmer K, Werner T, Melchert S, Petretich M, Rutkowska A, Vappiani J, Franken H, Steidel M, Sweetman GM, Gilan O, Lam EYN, Dawson MA, Prinjha RK, Grandi P, Bergamini G, Bantscheff M.

Cell. 2018 Mar 22;173(1):260-274.e25. doi: 10.1016/j.cell.2018.02.030. Epub 2018 Mar 15.

31.

Integer lattice gas with Monte Carlo collision operator recovers the lattice Boltzmann method with Poisson-distributed fluctuations.

Blommel T, Wagner AJ.

Phys Rev E. 2018 Feb;97(2-1):023310. doi: 10.1103/PhysRevE.97.023310.

PMID:
29548240
32.

Lattice gas with molecular dynamics collision operator.

Parsa MR, Wagner AJ.

Phys Rev E. 2017 Jul;96(1-1):013314. doi: 10.1103/PhysRevE.96.013314. Epub 2017 Jul 21.

PMID:
29347105
33.

Lived Experiences of Adolescent Athletes Following Sport-Related Concussion.

Valovich McLeod TC, Wagner AJ, Bacon CEW.

Orthop J Sports Med. 2017 Dec 11;5(12):2325967117745033. doi: 10.1177/2325967117745033. eCollection 2017 Dec.

34.

The significance of organ prolapse in gastroschisis.

Koehler SM, Szabo A, Loichinger M, Peterson E, Christensen M, Wagner AJ.

J Pediatr Surg. 2017 Dec;52(12):1972-1976. doi: 10.1016/j.jpedsurg.2017.08.066. Epub 2017 Sep 5.

PMID:
28951014
35.

Outcomes of gastroschisis early delivery: A systematic review and meta-analysis.

Landisch RM, Yin Z, Christensen M, Szabo A, Wagner AJ.

J Pediatr Surg. 2017 Dec;52(12):1962-1971. doi: 10.1016/j.jpedsurg.2017.08.068. Epub 2017 Sep 7. Review.

PMID:
28947324
36.

Publisher's Note: Fluctuating lattice Boltzmann method for the diffusion equation [Phys. Rev. E 94, 033302 (2016)].

Wagner AJ, Strand K.

Phys Rev E. 2017 Jun;95(6-2):069903. doi: 10.1103/PhysRevE.95.069903. Epub 2017 Jun 22.

PMID:
28709285
37.

Fourth-order analysis of a diffusive lattice Boltzmann method for barrier coatings.

Strand KT, Feickert AJ, Wagner AJ.

Phys Rev E. 2017 Jun;95(6-1):063311. doi: 10.1103/PhysRevE.95.063311. Epub 2017 Jun 20.

PMID:
28709205
38.

Infectious outcomes of gastroschisis patients with intraoperative hypothermia.

Landisch RM, Massoumi RL, Christensen M, Wagner AJ.

J Surg Res. 2017 Jul;215:93-97. doi: 10.1016/j.jss.2017.03.053. Epub 2017 Apr 6.

PMID:
28688668
39.

Click chemistry enables preclinical evaluation of targeted epigenetic therapies.

Tyler DS, Vappiani J, Cañeque T, Lam EYN, Ward A, Gilan O, Chan YC, Hienzsch A, Rutkowska A, Werner T, Wagner AJ, Lugo D, Gregory R, Ramirez Molina C, Garton N, Wellaway CR, Jackson S, MacPherson L, Figueiredo M, Stolzenburg S, Bell CC, House C, Dawson SJ, Hawkins ED, Drewes G, Prinjha RK, Rodriguez R, Grandi P, Dawson MA.

Science. 2017 Jun 30;356(6345):1397-1401. doi: 10.1126/science.aal2066. Epub 2017 Jun 15.

40.

Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.

Thomson DW, Wagner AJ, Bantscheff M, Benson RE, Dittus L, Duempelfeld B, Drewes G, Krause J, Moore JT, Mueller K, Poeckel D, Rau C, Salzer E, Shewchuk L, Hopf C, Emery JG, Muelbaier M.

J Med Chem. 2017 Jul 13;60(13):5455-5471. doi: 10.1021/acs.jmedchem.7b00137. Epub 2017 Jun 27.

PMID:
28591512
41.

Determination of the Absolute Configuration of β-Chiral Primary Alcohols Using the Competing Enantioselective Conversion Method.

Burns AS, Wagner AJ, Fulton JL, Young K, Zakarian A, Rychnovsky SD.

Org Lett. 2017 Jun 2;19(11):2953-2956. doi: 10.1021/acs.orglett.7b01189. Epub 2017 May 16.

42.

Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis.

Wagner AJ, Zubarev DY, Aspuru-Guzik A, Blackmond DG.

ACS Cent Sci. 2017 Apr 26;3(4):322-328. doi: 10.1021/acscentsci.7b00085. Epub 2017 Mar 21.

43.

Immunotherapy with single agent nivolumab for advanced leiomyosarcoma of the uterus: Results of a phase 2 study.

Ben-Ami E, Barysauskas CM, Solomon S, Tahlil K, Malley R, Hohos M, Polson K, Loucks M, Severgnini M, Patel T, Cunningham A, Rodig SJ, Hodi FS, Morgan JA, Merriam P, Wagner AJ, Shapiro GI, George S.

Cancer. 2017 Sep 1;123(17):3285-3290. doi: 10.1002/cncr.30738. Epub 2017 Apr 25.

44.

A phase II study of a human anti-PDGFRα monoclonal antibody (olaratumab, IMC-3G3) in previously treated patients with metastatic gastrointestinal stromal tumors.

Wagner AJ, Kindler H, Gelderblom H, Schöffski P, Bauer S, Hohenberger P, Kopp HG, Lopez-Martin JA, Peeters M, Reichardt P, Qin A, Nippgen J, Ilaria RL, Rutkowski P.

Ann Oncol. 2017 Mar 1;28(3):541-546. doi: 10.1093/annonc/mdw659.

45.

YWHAE-rearranged high-grade endometrial stromal sarcoma: Two-center case series and response to chemotherapy.

Hemming ML, Wagner AJ, Nucci MR, Chiang S, Wang L, Hensley ML, George S.

Gynecol Oncol. 2017 Jun;145(3):531-535. doi: 10.1016/j.ygyno.2017.03.021. Epub 2017 Apr 5.

46.

A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours.

de Jonge M, de Weger VA, Dickson MA, Langenberg M, Le Cesne A, Wagner AJ, Hsu K, Zheng W, Macé S, Tuffal G, Thomas K, Schellens JH.

Eur J Cancer. 2017 May;76:144-151. doi: 10.1016/j.ejca.2017.02.005. Epub 2017 Mar 17.

PMID:
28324749
47.

Phase I Trial of the Human Double Minute 2 Inhibitor MK-8242 in Patients With Advanced Solid Tumors.

Wagner AJ, Banerji U, Mahipal A, Somaiah N, Hirsch H, Fancourt C, Johnson-Levonas AO, Lam R, Meister AK, Russo G, Knox CD, Rose S, Hong DS.

J Clin Oncol. 2017 Apr 20;35(12):1304-1311. doi: 10.1200/JCO.2016.70.7117. Epub 2017 Feb 27.

48.

Tuberculosis case finding and mortality prediction: added value of the clinical TBscore and biomarker suPAR.

Rudolf F, Wagner AJ, Back FM, Gomes VF, Aaby P, Østergaard L, Eugen-Olsen J, Wejse C.

Int J Tuberc Lung Dis. 2017 Jan 1;21(1):67-72. doi: 10.5588/ijtld.16.0404.

PMID:
28157467
49.

A definition of gentle ventilation in congenital diaphragmatic hernia: a survey of neonatologists and pediatric surgeons.

Farkouh-Karoleski C, Najaf T, Wynn J, Aspelund G, Chung WK, Stolar CJ, Mychaliska GB, Warner BW, Wagner AJ, Cusick RA, Lim FY, Schindel DT, Potoka D, Azarow K, Cotten CM, Hesketh A, Soffer S, Crombleholme T, Needelman H.

J Perinat Med. 2017 Dec 20;45(9):1031-1038. doi: 10.1515/jpm-2016-0271.

PMID:
28130958
50.

The Future of Prebiotic Chemistry.

Wagner AJ, Blackmond DG.

ACS Cent Sci. 2016 Nov 23;2(11):775-777. Epub 2016 Nov 11. No abstract available.

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