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Items: 1 to 50 of 179

1.

Technical Verification and Assessment of Independent Validation of Biomarker Models for Endometriosis.

O DF, Fassbender A, Van Bree R, Laenen A, Peterse DP, Vanhie A, Waelkens E, D'Hooghe TM.

Biomed Res Int. 2019 Jul 25;2019:3673060. doi: 10.1155/2019/3673060. eCollection 2019.

2.

Evaluation of Distance Metrics and Spatial Autocorrelation in Uniform Manifold Approximation and Projection Applied to Mass Spectrometry Imaging Data.

Smets T, Verbeeck N, Claesen M, Asperger A, Griffioen G, Tousseyn T, Waelput W, Waelkens E, De Moor B.

Anal Chem. 2019 May 7;91(9):5706-5714. doi: 10.1021/acs.analchem.8b05827. Epub 2019 Apr 25.

PMID:
30986042
3.

Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells.

Vig S, Buitinga M, Rondas D, Crèvecoeur I, van Zandvoort M, Waelkens E, Eizirik DL, Gysemans C, Baatsen P, Mathieu C, Overbergh L.

Cell Death Dis. 2019 Apr 5;10(4):309. doi: 10.1038/s41419-019-1518-0.

4.

Structures of the heart specific SERCA2a Ca2+-ATPase.

Sitsel A, De Raeymaecker J, Drachmann ND, Derua R, Smaardijk S, Andersen JL, Vandecaetsbeek I, Chen J, De Maeyer M, Waelkens E, Olesen C, Vangheluwe P, Nissen P.

EMBO J. 2019 Mar 1;38(5). pii: e100020. doi: 10.15252/embj.2018100020. Epub 2019 Feb 18.

PMID:
30777856
5.

Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons.

Stakenborg N, Labeeuw E, Gomez-Pinilla PJ, De Schepper S, Aerts R, Goverse G, Farro G, Appeltans I, Meroni E, Stakenborg M, Viola MF, Gonzalez-Dominguez E, Bosmans G, Alpizar YA, Wolthuis A, D'Hoore A, Van Beek K, Verheijden S, Verhaegen M, Derua R, Waelkens E, Moretti M, Gotti C, Augustijns P, Talavera K, Vanden Berghe P, Matteoli G, Boeckxstaens GE.

Gut. 2019 Aug;68(8):1406-1416. doi: 10.1136/gutjnl-2018-317263. Epub 2018 Nov 24.

6.

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.

Buitinga M, Callebaut A, Marques Câmara Sodré F, Crèvecoeur I, Blahnik-Fagan G, Yang ML, Bugliani M, Arribas-Layton D, Marré M, Cook DP, Waelkens E, Mallone R, Piganelli JD, Marchetti P, Mamula MJ, Derua R, James EA, Mathieu C, Overbergh L.

Diabetes. 2018 Nov;67(11):2337-2348. doi: 10.2337/db18-0295.

7.

Wheat (Triticum aestivum L.) lipid species distribution in the different stages of straight dough bread making.

Janssen F, Wouters AGB, Pareyt B, Gerits LR, Delcour JA, Waelkens E, Derua R.

Food Res Int. 2018 Oct;112:299-311. doi: 10.1016/j.foodres.2018.06.038. Epub 2018 Jun 21.

PMID:
30131141
8.

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

Talebi A, Dehairs J, Rambow F, Rogiers A, Nittner D, Derua R, Vanderhoydonc F, Duarte JAG, Bosisio F, Van den Eynde K, Nys K, Pérez MV, Agostinis P, Waelkens E, Van den Oord J, Fendt SM, Marine JC, Swinnen JV.

Nat Commun. 2018 Jun 27;9(1):2500. doi: 10.1038/s41467-018-04664-0.

9.

Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation.

Cobbaut M, Derua R, Parker PJ, Waelkens E, Janssens V, Van Lint J.

FEBS Lett. 2018 Jul;592(14):2432-2443. doi: 10.1002/1873-3468.13171. Epub 2018 Jul 23.

10.

Noninvasive diagnosis of endometriosis: Review of current peripheral blood and endometrial biomarkers.

O DF, Flores I, Waelkens E, D'Hooghe T.

Best Pract Res Clin Obstet Gynaecol. 2018 Jul;50:72-83. doi: 10.1016/j.bpobgyn.2018.04.001. Epub 2018 Apr 13. Review.

PMID:
29778458
11.

Identification of SP1683 as a pneumococcal protein that is protective against nasopharyngeal colonization.

Moens L, Hermand P, Wellens T, Wuyts G, Derua R, Waelkens E, Ysebaert C, Godfroid F, Bossuyt X.

Hum Vaccin Immunother. 2018 May 4;14(5):1234-1242. doi: 10.1080/21645515.2018.1430541. Epub 2018 Feb 21.

12.

APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel KV10.1.

Moreels L, Peigneur S, Galan DT, De Pauw E, Béress L, Waelkens E, Pardo LA, Quinton L, Tytgat J.

Mar Drugs. 2017 Sep 13;15(9). pii: E287. doi: 10.3390/md15090287.

13.

Evaluation of Total, Active, and Specific Myeloperoxidase Levels in Women with and without Endometriosis.

O DF, Waelkens E, Peterse DP, Lebovic D, Meuleman C, Tomassetti C, Peeraer K, Alvarez Real A, Bosseloir A, D'Hooghe T, Fassbender A.

Gynecol Obstet Invest. 2018;83(2):133-139. doi: 10.1159/000475664. Epub 2017 May 17.

PMID:
28511185
14.

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.

Cobbaut M, Derua R, Döppler H, Lou HJ, Vandoninck S, Storz P, Turk BE, Seufferlein T, Waelkens E, Janssens V, Van Lint J.

Sci Rep. 2017 Apr 20;7(1):887. doi: 10.1038/s41598-017-00800-w.

15.

Lipid degradation promotes prostate cancer cell survival.

Itkonen HM, Brown M, Urbanucci A, Tredwell G, Ho Lau C, Barfeld S, Hart C, Guldvik IJ, Takhar M, Heemers HV, Erho N, Bloch K, Davicioni E, Derua R, Waelkens E, Mohler JL, Clarke N, Swinnen JV, Keun HC, Rekvig OP, Mills IG.

Oncotarget. 2017 Jun 13;8(24):38264-38275. doi: 10.18632/oncotarget.16123.

16.

The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling.

van Vliet AR, Giordano F, Gerlo S, Segura I, Van Eygen S, Molenberghs G, Rocha S, Houcine A, Derua R, Verfaillie T, Vangindertael J, De Keersmaecker H, Waelkens E, Tavernier J, Hofkens J, Annaert W, Carmeliet P, Samali A, Mizuno H, Agostinis P.

Mol Cell. 2017 Mar 2;65(5):885-899.e6. doi: 10.1016/j.molcel.2017.01.020. Epub 2017 Feb 23.

17.

1β,25-Dihydroxyvitamin D3: A new vitamin D metabolite in human serum.

Pauwels S, Jans I, Billen J, Heijboer A, Verstuyf A, Carmeliet G, Mathieu C, Maestro M, Waelkens E, Evenepoel P, Bouillon R, Vanderschueren D, Vermeersch P.

J Steroid Biochem Mol Biol. 2017 Oct;173:341-348. doi: 10.1016/j.jsbmb.2017.02.004. Epub 2017 Feb 11.

PMID:
28193495
18.

Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis.

Crèvecoeur I, Gudmundsdottir V, Vig S, Marques Câmara Sodré F, D'Hertog W, Fierro AC, Van Lommel L, Gysemans C, Marchal K, Waelkens E, Schuit F, Brunak S, Overbergh L, Mathieu C.

Diabetologia. 2017 Mar;60(3):475-489. doi: 10.1007/s00125-016-4191-1. Epub 2017 Jan 12.

PMID:
28078386
19.

Split-BioID: a proximity biotinylation assay for dimerization-dependent protein interactions.

De Munter S, Görnemann J, Derua R, Lesage B, Qian J, Heroes E, Waelkens E, Van Eynde A, Beullens M, Bollen M.

FEBS Lett. 2017 Jan;591(2):415-424. doi: 10.1002/1873-3468.12548. Epub 2017 Jan 12.

20.

Multiplex immunoassays in endometriosis: An array of possibilities.

O DF, El Aalamat Y, Waelkens E, De Moor B, D'Hooghe T, Fassbender A.

Front Biosci (Landmark Ed). 2017 Jan 1;22:479-492. Review.

PMID:
27814626
21.

Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.

Lebbe EK, Ghequire MG, Peigneur S, Mille BG, Devi P, Ravichandran S, Waelkens E, D'Souza L, De Mot R, Tytgat J.

Mar Drugs. 2016 Oct 27;14(11). pii: E199.

22.

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins.

Cremonez CM, Maiti M, Peigneur S, Cassoli JS, Dutra AA, Waelkens E, Lescrinier E, Herdewijn P, de Lima ME, Pimenta AM, Arantes EC, Tytgat J.

Toxins (Basel). 2016 Sep 30;8(10). pii: E288.

23.

Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: A focus on the inhibitory effect on the oncogenic channel Kv10.1.

Moreels L, Peigneur S, Yamaguchi Y, Vriens K, Waelkens E, Zhu S, Thevissen K, Cammue BPA, Sato K, Tytgat J.

Peptides. 2017 Dec;98:43-50. doi: 10.1016/j.peptides.2016.08.008. Epub 2016 Aug 28.

PMID:
27578329
24.

Differential diagnosis of gallstones by using hypericin as a fluorescent optical imaging agent.

Miranda Cona M, Liu YW, Hubert A, Yin T, Feng YB, de Witte P, Waelkens E, Jiang YS, Zhang J, Mulier S, Xia Q, Huang G, Oyen R, Ni YC.

World J Gastroenterol. 2016 Aug 7;22(29):6690-705. doi: 10.3748/wjg.v22.i29.6690.

25.

Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth.

Haesen D, Abbasi Asbagh L, Derua R, Hubert A, Schrauwen S, Hoorne Y, Amant F, Waelkens E, Sablina A, Janssens V.

Cancer Res. 2016 Oct 1;76(19):5719-5731. Epub 2016 Aug 2.

26.

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.

Sannerud R, Esselens C, Ejsmont P, Mattera R, Rochin L, Tharkeshwar AK, De Baets G, De Wever V, Habets R, Baert V, Vermeire W, Michiels C, Groot AJ, Wouters R, Dillen K, Vints K, Baatsen P, Munck S, Derua R, Waelkens E, Basi GS, Mercken M, Vooijs M, Bollen M, Schymkowitz J, Rousseau F, Bonifacino JS, Van Niel G, De Strooper B, Annaert W.

Cell. 2016 Jun 30;166(1):193-208. doi: 10.1016/j.cell.2016.05.020. Epub 2016 Jun 9.

27.

Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.

Marien E, Meister M, Muley T, Gomez Del Pulgar T, Derua R, Spraggins JM, Van de Plas R, Vanderhoydonc F, Machiels J, Binda MM, Dehairs J, Willette-Brown J, Hu Y, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Lacal JC, Waelkens E, Swinnen JV.

Oncotarget. 2016 Mar 15;7(11):12582-97. doi: 10.18632/oncotarget.7179.

28.

SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells.

Elong Edimo W, Ghosh S, Derua R, Janssens V, Waelkens E, Vanderwinden JM, Robe P, Erneux C.

J Cell Sci. 2016 Mar 15;129(6):1101-14. doi: 10.1242/jcs.179663. Epub 2016 Jan 29.

29.

p53 attenuates AKT signaling by modulating membrane phospholipid composition.

Rueda-Rincon N, Bloch K, Derua R, Vyas R, Harms A, Hankemeier T, Khan NA, Dehairs J, Bagadi M, Binda MM, Waelkens E, Marine JC, Swinnen JV.

Oncotarget. 2015 Aug 28;6(25):21240-54.

30.

Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3.

Gijs HL, Willemarck N, Vanderhoydonc F, Khan NA, Dehairs J, Derua R, Waelkens E, Taketomi Y, Murakami M, Agostinis P, Annaert W, Swinnen JV.

Mol Biol Cell. 2015 Jun 15;26(12):2321-32. doi: 10.1091/mbc.E14-10-1472. Epub 2015 Apr 22.

31.

Different ligands of the TRPV3 cation channel cause distinct conformational changes as revealed by intrinsic tryptophan fluorescence quenching.

Billen B, Brams M, Debaveye S, Remeeva A, Alpizar YA, Waelkens E, Kreir M, Brüggemann A, Talavera K, Nilius B, Voets T, Ulens C.

J Biol Chem. 2015 May 15;290(20):12964-74. doi: 10.1074/jbc.M114.628925. Epub 2015 Mar 31.

32.

Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles.

Marien E, Meister M, Muley T, Fieuws S, Bordel S, Derua R, Spraggins J, Van de Plas R, Dehairs J, Wouters J, Bagadi M, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Waelkens E, Swinnen JV.

Int J Cancer. 2015 Oct 1;137(7):1539-48. doi: 10.1002/ijc.29517. Epub 2015 Apr 7.

33.

A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death.

Rondas D, Gudmundsdottir V, D'Hertog W, Crèvecoeur I, Waelkens E, Brunak S, Mathieu C, Overbergh L.

Proteomics Clin Appl. 2015 Oct;9(9-10):938-52. doi: 10.1002/prca.201400124. Epub 2015 Apr 11.

PMID:
25712914
34.

Remodeling of phospholipid composition in colon cancer cells by 1α,25(OH)2D3 and its analogs.

Leyssens C, Marien E, Verlinden L, Derua R, Waelkens E, Swinnen JV, Verstuyf A.

J Steroid Biochem Mol Biol. 2015 Apr;148:172-8. doi: 10.1016/j.jsbmb.2015.01.018. Epub 2015 Jan 24. Review.

PMID:
25625664
35.

Mass Spectrometry of Flame Figures.

Wouters J, Waelkens E, Vandoninck S, Segaert S, van den Oord JJ.

Acta Derm Venereol. 2015 Jul;95(6):734-5. doi: 10.2340/00015555-2050. No abstract available.

36.

Discovery of a new subclass of α-conotoxins in the venom of Conus australis.

Lebbe EK, Peigneur S, Maiti M, Mille BG, Devi P, Ravichandran S, Lescrinier E, Waelkens E, D'Souza L, Herdewijn P, Tytgat J.

Toxicon. 2014 Dec;91:145-54. doi: 10.1016/j.toxicon.2014.08.074. Epub 2014 Sep 4.

PMID:
25194747
37.

Automated anatomical interpretation of ion distributions in tissue: linking imaging mass spectrometry to curated atlases.

Verbeeck N, Yang J, De Moor B, Caprioli RM, Waelkens E, Van de Plas R.

Anal Chem. 2014 Sep 16;86(18):8974-82. doi: 10.1021/ac502838t. Epub 2014 Aug 25.

38.

Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.

Reyniers L, Del Giudice MG, Civiero L, Belluzzi E, Lobbestael E, Beilina A, Arrigoni G, Derua R, Waelkens E, Li Y, Crosio C, Iaccarino C, Cookson MR, Baekelandt V, Greggio E, Taymans JM.

J Neurochem. 2014 Oct;131(2):239-50. doi: 10.1111/jnc.12798. Epub 2014 Jul 14.

39.

Structure-function elucidation of a new α-conotoxin, Lo1a, from Conus longurionis.

Lebbe EK, Peigneur S, Maiti M, Devi P, Ravichandran S, Lescrinier E, Ulens C, Waelkens E, D'Souza L, Herdewijn P, Tytgat J.

J Biol Chem. 2014 Apr 4;289(14):9573-83. doi: 10.1074/jbc.M114.556175. Epub 2014 Feb 24.

40.

In vitro phosphorylation does not influence the aggregation kinetics of WT α-synuclein in contrast to its phosphorylation mutants.

Schreurs S, Gerard M, Derua R, Waelkens E, Taymans JM, Baekelandt V, Engelborghs Y.

Int J Mol Sci. 2014 Jan 15;15(1):1040-67. doi: 10.3390/ijms15011040.

41.

Tissue specific analysis reveals a differential organization and regulation of both ethylene biosynthesis and E8 during climacteric ripening of tomato.

Van de Poel B, Vandenzavel N, Smet C, Nicolay T, Bulens I, Mellidou I, Vandoninck S, Hertog ML, Derua R, Spaepen S, Vanderleyden J, Waelkens E, De Proft MP, Nicolai BM, Geeraerd AH.

BMC Plant Biol. 2014 Jan 8;14:11. doi: 10.1186/1471-2229-14-11.

42.

Platelets of mice heterozygous for neurobeachin, a candidate gene for autism spectrum disorder, display protein changes related to aberrant protein kinase A activity.

Nuytens K, Tuand K, Di Michele M, Boonen K, Waelkens E, Freson K, Creemers JW.

Mol Autism. 2013 Nov 4;4(1):43. doi: 10.1186/2040-2392-4-43.

43.

A proteomic approach on the effects of TX527, a 1α,25-dihydroxyvitamin D3 analog, in human T lymphocytes.

Ferreira GB, Baeke F, Verstuyf A, De Clercq P, Waelkens E, Mathieu C, Overbergh L.

J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:96-101. doi: 10.1016/j.jsbmb.2013.10.013. Epub 2013 Oct 28.

PMID:
24176759
44.

The metabolic response of cultured tomato cells to low oxygen stress.

Ampofo-Asiama J, Baiye VM, Hertog ML, Waelkens E, Geeraerd AH, Nicolai BM.

Plant Biol (Stuttg). 2014 May;16(3):594-606. doi: 10.1111/plb.12094. Epub 2013 Sep 30.

PMID:
24119171
45.

Reply of the authors.

Fassbender A, Vodolazkaia A, Saunders P, Lebovic D, Waelkens E, De Moor B, D'Hooghe T.

Fertil Steril. 2013 Oct;100(4):e20. doi: 10.1016/j.fertnstert.2013.07.010. Epub 2013 Aug 15. No abstract available.

PMID:
23954355
46.

Glucagon-like peptide-1 protects human islets against cytokine-mediated β-cell dysfunction and death: a proteomic study of the pathways involved.

Rondas D, Bugliani M, D'Hertog W, Lage K, Masini M, Waelkens E, Marchetti P, Mathieu C, Overbergh L.

J Proteome Res. 2013 Sep 6;12(9):4193-206. doi: 10.1021/pr400527q. Epub 2013 Aug 26.

PMID:
23937086
47.

Functional studies and proteomics in platelets and fibroblasts reveal a lysosomal defect with increased cathepsin-dependent apoptosis in ATP1A3 defective alternating hemiplegia of childhood.

Di Michele M, Goubau C, Waelkens E, Thys C, De Vos R, Overbergh L, Schyns T, Buyse G, Casaer P, Van Geet C, Freson K.

J Proteomics. 2013 Jun 28;86:53-69. doi: 10.1016/j.jprot.2013.05.005. Epub 2013 May 13.

PMID:
23681173
48.

Cellular and ultra structural evidence for cytoskeletal localization of prolyl endopeptidase-like protein in neurons.

Morawski M, Nuytens K, Juhasz T, Zeitschel U, Seeger G, Waelkens E, Regal L, Schulz I, Arendt T, Szeltner Z, Creemers J, Rossner S.

Neuroscience. 2013 Jul 9;242:128-39. doi: 10.1016/j.neuroscience.2013.02.038. Epub 2013 Feb 26.

PMID:
23485813
49.

Biomarkers of endometriosis.

Fassbender A, Vodolazkaia A, Saunders P, Lebovic D, Waelkens E, De Moor B, D'Hooghe T.

Fertil Steril. 2013 Mar 15;99(4):1135-45. doi: 10.1016/j.fertnstert.2013.01.097. Epub 2013 Feb 13. Review.

PMID:
23414923
50.

Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction.

Maris M, Robert S, Waelkens E, Derua R, Hernangomez MH, D'Hertog W, Cnop M, Mathieu C, Overbergh L.

J Proteome Res. 2013 Jan 4;12(1):347-62. doi: 10.1021/pr300596g. Epub 2012 Dec 4.

PMID:
23170928

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