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M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera.

Konar A, Gupta R, Shukla RK, Maloney B, Khanna VK, Wadhwa R, Lahiri DK, Thakur MK.

Sci Rep. 2019 Sep 30;9(1):13990. doi: 10.1038/s41598-019-48238-6.


Express ELISA for detection of mortalin.

Garg S, Wu C, Ohmiya Y, Kaul SC, Wadhwa R.

Biotechniques. 2019 Oct;67(4):166-171. doi: 10.2144/btn-2018-0158. Epub 2019 Sep 10.


Folic Acid Receptor-Mediated Targeting Enhances the Cytotoxicity, Efficacy, and Selectivity of Withania somnifera Leaf Extract: In vitro and in vivo Evidence.

Yu Y, Wang J, Kaul SC, Wadhwa R, Miyako E.

Front Oncol. 2019 Jul 4;9:602. doi: 10.3389/fonc.2019.00602. eCollection 2019.


Interactions between microbiome and lungs: Paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases.

Chellappan DK, Sze Ning QL, Su Min SK, Bin SY, Chern PJ, Shi TP, Ee Mei SW, Yee TH, Qi OJ, Thangavelu L, Rajeshkumar S, Negi P, Chellian J, Wadhwa R, Gupta G, Collet T, Hansbro PM, Dua K.

Chem Biol Interact. 2019 Sep 1;310:108732. doi: 10.1016/j.cbi.2019.108732. Epub 2019 Jul 2. Review.


Red blood cells as an efficient in vitro model for evaluating the efficacy of metallic nanoparticles.

Wadhwa R, Aggarwal T, Thapliyal N, Kumar A, Priya, Yadav P, Kumari V, Reddy BSC, Chandra P, Maurya PK.

3 Biotech. 2019 Jul;9(7):279. doi: 10.1007/s13205-019-1807-4. Epub 2019 Jun 21. Review.


Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity: Molecular Evidence.

Garg S, Afzal S, Elwakeel A, Sharma D, Radhakrishnan N, Dhanjal JK, Sundar D, Kaul SC, Wadhwa R.

Mar Drugs. 2019 Jun 5;17(6). pii: E338. doi: 10.3390/md17060338.


Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases.

Mehta M, Deeksha, Tewari D, Gupta G, Awasthi R, Singh H, Pandey P, Chellappan DK, Wadhwa R, Collet T, Hansbro PM, Kumar SR, Thangavelu L, Negi P, Dua K, Satija S.

Chem Biol Interact. 2019 Aug 1;308:206-215. doi: 10.1016/j.cbi.2019.05.028. Epub 2019 May 25. Review.


Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.

Garg S, Huifu H, Kumari A, Sundar D, Kaul SC, Wadhwa R.

J Gerontol A Biol Sci Med Sci. 2019 May 21. pii: glz077. doi: 10.1093/gerona/glz077. [Epub ahead of print]


Modulation of Diacylglycerol-Induced Melanogenesis in Human Melanoma and Primary Melanocytes: Role of Stress Chaperone Mortalin.

Wadhwa R, Li L, Singh R, Wang J, Gao R, Nigam N, Forestier S, Ando N, Kaul SC.

Evid Based Complement Alternat Med. 2019 Apr 14;2019:9848969. doi: 10.1155/2019/9848969. eCollection 2019.


Prevention and management of bowel injury during gynecologic laparoscopy: an update.

Eisner IS, Wadhwa RK, Downing KT, Singhal PK.

Curr Opin Obstet Gynecol. 2019 Aug;31(4):245-250. doi: 10.1097/GCO.0000000000000552.


Hypokalemic Periodic Paralysis and Spectrum of Thyroid Disorders: Analysis of 7 Cases from Northern India.

Aggarwal A, Wadhwa R, Pande A, Sahu M, Kapoor D, Khanna R.

Indian J Endocrinol Metab. 2019 Jan-Feb;23(1):168-170. doi: 10.4103/ijem.IJEM_619_18. No abstract available.


High Prevalence of Genital Mycotic Infections with Sodium-glucose Co-transporter 2 Inhibitors among Indian Patients with Type 2 Diabetes.

Aggarwal A, Wadhwa R, Kapoor D, Khanna R.

Indian J Endocrinol Metab. 2019 Jan-Feb;23(1):9-13. doi: 10.4103/ijem.IJEM_244_18.


Anti-Stress and Glial Differentiation Effects of a Novel Combination of Cucurbitacin B and Withanone (CucWi-N): Experimental Evidence.

Garg S, Kaul SC, Wadhwa R.

Ann Neurosci. 2018 Dec;25(4):201-209. doi: 10.1159/000490693. Epub 2018 Jul 5.


The 2019 mathematical oncology roadmap.

Rockne RC, Hawkins-Daarud A, Swanson KR, Sluka JP, Glazier JA, Macklin P, Hormuth DA, Jarrett AM, Lima EABF, Tinsley Oden J, Biros G, Yankeelov TE, Curtius K, Al Bakir I, Wodarz D, Komarova N, Aparicio L, Bordyuh M, Rabadan R, Finley SD, Enderling H, Caudell J, Moros EG, Anderson ARA, Gatenby RA, Kaznatcheev A, Jeavons P, Krishnan N, Pelesko J, Wadhwa RR, Yoon N, Nichol D, Marusyk A, Hinczewski M, Scott JG.

Phys Biol. 2019 Jun 19;16(4):041005. doi: 10.1088/1478-3975/ab1a09.


Primary Hyperparathyroidism in Pregnancy: A Multicenter Case Series of 4 Patients from Northern India.

Aggarwal A, Wadhwa R, Aggarwal V, Pande A, Singh SK, Gahlot A, Singh DN, Sharma A.

J Obstet Gynaecol India. 2019 Apr;69(Suppl 1):31-35. doi: 10.1007/s13224-018-1148-y. Epub 2018 Jul 5. No abstract available.


Identification of biomarkers and genetic approaches toward chronic obstructive pulmonary disease.

Wadhwa R, Aggarwal T, Malyla V, Kumar N, Gupta G, Chellappan DK, Dureja H, Mehta M, Satija S, Gulati M, Maurya PK, Collet T, Hansbro PM, Dua K.

J Cell Physiol. 2019 Aug;234(10):16703-16723. doi: 10.1002/jcp.28482. Epub 2019 Mar 25. Review.


Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin.

Afzal S, Garg S, Ishida Y, Terao K, Kaul SC, Wadhwa R.

Mar Drugs. 2019 Mar 23;17(3). pii: E189. doi: 10.3390/md17030189.


Interactions with the macrophages: An emerging targeted approach using novel drug delivery systems in respiratory diseases.

Mehta M, Deeksha, Sharma N, Vyas M, Khurana N, Maurya PK, Singh H, Andreoli de Jesus TP, Dureja H, Chellappan DK, Gupta G, Wadhwa R, Collet T, Hansbro PM, Dua K, Satija S.

Chem Biol Interact. 2019 May 1;304:10-19. doi: 10.1016/j.cbi.2019.02.021. Epub 2019 Mar 5. Review.


Wild type p53 function in p53Y220C mutant harboring cells by treatment with Ashwagandha derived anticancer withanolides: bioinformatics and experimental evidence.

Sundar D, Yu Y, Katiyar SP, Putri JF, Dhanjal JK, Wang J, Sari AN, Kolettas E, Kaul SC, Wadhwa R.

J Exp Clin Cancer Res. 2019 Feb 26;38(1):103. doi: 10.1186/s13046-019-1099-x.


TAS0728, A Covalent-binding, HER2-selective Kinase Inhibitor Shows Potent Antitumor Activity in Preclinical Models.

Irie H, Ito K, Fujioka Y, Oguchi K, Fujioka A, Hashimoto A, Ohsawa H, Tanaka K, Funabashi K, Araki H, Kawai Y, Shimamura T, Wadhwa R, Ohkubo S, Matsuo K.

Mol Cancer Ther. 2019 Apr;18(4):733-742. doi: 10.1158/1535-7163.MCT-18-1085. Epub 2019 Feb 20.


Long-term dental and skeletal effects of mandibular advancement devices in adults with obstructive sleep apnoea: A systematic review.

Patel S, Rinchuse D, Zullo T, Wadhwa R.

Int Orthod. 2019 Mar;17(1):3-11. doi: 10.1016/j.ortho.2019.01.004. Epub 2019 Feb 13.


An Innovative Method to Determine the Width of Maxillary Anterior Teeth with the Help of Measurements Obtained from the Master Cast.

Shivaji JM, Vaidya P, Thippanna RK, Wadhwa R, Wadhwa A, Gandhi P.

J Contemp Dent Pract. 2018 Dec 1;19(12):1487-1492.


Improving Adolescent Health Services across High Priority Districts in 6 States of India: Learnings from an Integrated Reproductive Maternal Newborn Child and Adolescent Health Project.

Wadhwa R, Chaudhary N, Bisht N, Gupta A, Behera N, Verma AK, Chopra M, Jain M, Verma G, Gupta S, Taneja G, Gera R.

Indian J Community Med. 2018 Dec;43(Suppl 1):S6-S11. doi: 10.4103/ijcm.IJCM_38_18.


Oxidative Stress and Accelerated Aging in Neurodegenerative and Neuropsychiatric Disorder.

Wadhwa R, Gupta R, Maurya PK.

Curr Pharm Des. 2018;24(40):4711-4725. doi: 10.2174/1381612825666190115121018.


A comparative study of chemically synthesized and Camellia sinensis leaf extract-mediated silver nanoparticles.

Kumar V, Wadhwa R, Kumar N, Maurya PK.

3 Biotech. 2019 Jan;9(1):7. doi: 10.1007/s13205-018-1544-0. Epub 2019 Jan 2.


Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.

Dua K, Malyla V, Singhvi G, Wadhwa R, Krishna RV, Shukla SD, Shastri MD, Chellappan DK, Maurya PK, Satija S, Mehta M, Gulati M, Hansbro N, Collet T, Awasthi R, Gupta G, Hsu A, Hansbro PM.

Chem Biol Interact. 2019 Feb 1;299:168-178. doi: 10.1016/j.cbi.2018.12.009. Epub 2018 Dec 13. Review.


Identification and Functional Characterization of Anti-metastasis and Anti-angiogenic Activities of Triethylene Glycol Derivatives.

Oh E, Garg S, Liu Y, Afzal S, Gao R, Yun CO, Kaul SC, Wadhwa R.

Front Oncol. 2018 Nov 28;8:552. doi: 10.3389/fonc.2018.00552. eCollection 2018.


Spectroscopic determination of intracellular quercetin uptake using erythrocyte model and its implications in human aging.

Kumar P, Wadhwa R, Gupta R, Chandra P, Maurya PK.

3 Biotech. 2018 Dec;8(12):498. doi: 10.1007/s13205-018-1524-4. Epub 2018 Nov 26.


The accuracy of computer-based diagnostic tools for the identification of concurrent genetic disorders.

Wadhwa RR, Park DY, Natowicz MR.

Am J Med Genet A. 2018 Dec;176(12):2704-2709. doi: 10.1002/ajmg.a.40651. Epub 2018 Nov 26.


White matter hyperintensities in young individuals with bipolar disorder or at high genetic risk.

Wadhwa R, Wen W, Frankland A, Leung V, Sinbandhit C, Stuart A, Dawes L, Hadzi-Pavlovic D, Levy F, Lenrootl R, Mitchell PB, Roberts G.

J Affect Disord. 2019 Feb 15;245:228-236. doi: 10.1016/j.jad.2018.10.368. Epub 2018 Nov 2.


Achieving Early Mother-baby Skin-to-skin Contact in Caesarean Section: A Quality Improvement Initiative.

Maria A, Shukla A, Wadhwa R, Kaur B, Sarkar B, Kaur M.

Indian Pediatr. 2018 Sep 15;55(9):765-767.


A Man (or a Woman) is Known by the Company He/She Keeps.

Wadhwa R.

J Insur Med. 2018 Jan;47(3):141-142. doi: 10.17849/insm-47-03-141-142.1. No abstract available.


Oxidative, inflammatory, genetic, and epigenetic biomarkers associated with chronic obstructive pulmonary disorder.

Aggarwal T, Wadhwa R, Thapliyal N, Sharma K, Rani V, Maurya PK.

J Cell Physiol. 2019 Mar;234(3):2067-2082. doi: 10.1002/jcp.27181. Epub 2018 Sep 1. Review.


Comparison of Nuclear Matrix and Mitotic Chromosome Scaffold Proteins in Drosophila S2 Cells-Transmission of Hallmarks of Nuclear Organization Through Mitosis.

Sureka R, Wadhwa R, Thakur SS, Pathak RU, Mishra RK.

Mol Cell Proteomics. 2018 Oct;17(10):1965-1978. doi: 10.1074/mcp.RA118.000591. Epub 2018 Jul 10.


Sagittal Alignment of the Lumbar Spine.

Berven S, Wadhwa R.

Neurosurg Clin N Am. 2018 Jul;29(3):331-339. doi: 10.1016/ Review.


Integration of conventional cell viability assays for reliable and reproducible read-outs: experimental evidence.

Garg S, Huifu H, Kaul SC, Wadhwa R.

BMC Res Notes. 2018 Jun 22;11(1):403. doi: 10.1186/s13104-018-3512-5.


Reduced Efficacy of Insulin Detemir in Controlling Hyperglycemia during Pregnancy: An Interesting Case Report.

Pande A, Aggarwal A, Wadhwa R.

Indian J Endocrinol Metab. 2018 Mar-Apr;22(2):292-295. doi: 10.4103/ijem.IJEM_41_18. No abstract available.


Caffeic acid phenethyl ester (CAPE) possesses pro-hypoxia and anti-stress activities: bioinformatics and experimental evidences.

Bhargava P, Kumari A, Putri JF, Ishida Y, Terao K, Kaul SC, Sundar D, Wadhwa R.

Cell Stress Chaperones. 2018 Sep;23(5):1055-1068. doi: 10.1007/s12192-018-0915-0. Epub 2018 Jun 4.


CARF enrichment promotes epithelial-mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target.

Kalra RS, Chaudhary A, Yoon AR, Bhargava P, Omar A, Garg S, Yun CO, Kaul SC, Wadhwa R.

Oncogenesis. 2018 May 11;7(5):39. doi: 10.1038/s41389-018-0048-4.


TAS6417, A Novel EGFR Inhibitor Targeting Exon 20 Insertion Mutations.

Hasako S, Terasaka M, Abe N, Uno T, Ohsawa H, Hashimoto A, Fujita R, Tanaka K, Okayama T, Wadhwa R, Miyadera K, Aoyagi Y, Yonekura K, Matsuo K.

Mol Cancer Ther. 2018 Aug;17(8):1648-1658. doi: 10.1158/1535-7163.MCT-17-1206. Epub 2018 May 10.


Molecular Insights Into Withaferin-A-Induced Senescence: Bioinformatics and Experimental Evidence to the Role of NFκB and CARF.

Bhargava P, Malik V, Liu Y, Ryu J, Kaul SC, Sundar D, Wadhwa R.

J Gerontol A Biol Sci Med Sci. 2019 Jan 16;74(2):183-191. doi: 10.1093/gerona/gly107.


Actionable Locoregional Relapses after Therapy of Localized Esophageal Cancer: Insights from a Large Cohort.

Elimova E, Wang X, Qiao W, Sudo K, Wadhwa R, Shiozaki H, Shimodaira Y, Planjery V, Charalampakis N, Lee JH, Weston BR, Bhutani MS, Komaki R, Rice DC, Swisher SG, Blum MA, Rogers JE, Skinner HD, Maru DM, Hofstetter WL, Ajani JA.

Oncology. 2018;94(6):345-353. doi: 10.1159/000486720. Epub 2018 Apr 27.


Organic cultivation of Ashwagandha with improved biomass and high content of active Withanolides: Use of Vermicompost.

Kaur A, Singh B, Ohri P, Wang J, Wadhwa R, Kaul SC, Pati PK, Kaur A.

PLoS One. 2018 Apr 16;13(4):e0194314. doi: 10.1371/journal.pone.0194314. eCollection 2018.


Parathyroid Lipoadenoma: A Rare Entity.

Aggarwal A, Wadhwa R, Aggarwal V.

Indian J Endocrinol Metab. 2018 Jan-Feb;22(1):174-176. doi: 10.4103/ijem.IJEM_273_17. No abstract available.


Role of Endoscopic Findings and Biopsies in Renal Transplant Recipients With Gastrointestinal Complications: A Tertiary Care Experience.

Wadhwa RK, Nazeer A, Rai AA, Luck NH.

Exp Clin Transplant. 2018 Oct;16(5):522-527. doi: 10.6002/ect.2017.0132. Epub 2018 Mar 9.


Differential effects of serotonin reuptake inhibitors fluoxetine and escitalopram on bone markers and microarchitecture in Wistar rats.

Kumar M, Wadhwa R, Kothari P, Trivedi R, Vohora D.

Eur J Pharmacol. 2018 Apr 15;825:57-62. doi: 10.1016/j.ejphar.2018.02.026. Epub 2018 Feb 19.


Anticancer activity of the supercritical extract of Brazilian green propolis and its active component, artepillin C: Bioinformatics and experimental analyses of its mechanisms of action.

Bhargava P, Grover A, Nigam N, Kaul A, Doi M, Ishida Y, Kakuta H, Kaul SC, Terao K, Wadhwa R.

Int J Oncol. 2018 Mar;52(3):925-932. doi: 10.3892/ijo.2018.4249. Epub 2018 Jan 22.


Anticancer Activity in Honeybee Propolis: Functional Insights to the Role of Caffeic Acid Phenethyl Ester and Its Complex With γ-Cyclodextrin.

Ishida Y, Gao R, Shah N, Bhargava P, Furune T, Kaul SC, Terao K, Wadhwa R.

Integr Cancer Ther. 2018 Sep;17(3):867-873. doi: 10.1177/1534735417753545. Epub 2018 Feb 2.


Effect of escitalopram and carbidopa on bone markers in Wistar rats: a preliminary experimental study.

Wadhwa R, Kumar M, Paudel YN, Iqbal R, Kothari P, Trivedi R, Vohora D.

J Bone Miner Metab. 2019 Jan;37(1):36-42. doi: 10.1007/s00774-018-0908-1. Epub 2018 Jan 29.


Tumor suppressor activity of miR-451: Identification of CARF as a new target.

Li L, Gao R, Yu Y, Kaul Z, Wang J, Kalra RS, Zhang Z, Kaul SC, Wadhwa R.

Sci Rep. 2018 Jan 10;8(1):375. doi: 10.1038/s41598-017-18559-5.

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