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Items: 46

1.

Managing Complex Peripheral Nerve Injuries Within the Military Health System: A Multidisciplinary Approach to Treatment, Education, and Research at Walter Reed National Military Medical Center.

Wade SM, Nesti LJ, Cook GA, Bresner JS, Happel JP, Villahermosa AJ, Melendez-Munoz AM, Gomez YD, Reece DE, Miller ME, Souza JM.

Mil Med. 2019 Nov 30. pii: usz415. doi: 10.1093/milmed/usz415. [Epub ahead of print]

PMID:
31783405
2.

Pulsed Electromagnetic Field Stimulation Is a Practical Adjunctive Therapy for Fusion in Spine Surgery.

Wade SM, Clark DM, Fredericks DR Jr, Wagner SC.

Clin Spine Surg. 2019 Sep 13. doi: 10.1097/BSD.0000000000000880. [Epub ahead of print] No abstract available.

PMID:
31580260
3.

Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis.

Wade SM, Ohnesorge N, McLoughlin H, Biniecka M, Carter SP, Trenkman M, Cunningham CC, McGarry T, Canavan M, Kennedy BN, Veale DJ, Fearon U.

EBioMedicine. 2019 Sep;47:402-413. doi: 10.1016/j.ebiom.2019.08.043. Epub 2019 Aug 26.

4.

The Inverted Free Functioning Gracilis Muscle Transfer For Restoration of Elbow Flexion Following Delayed Presentation or Failed Primary Nerve Reconstruction of Upper Trunk Injuries.

Wade SM, Nesti LJ, Wind GG, Howard RT, Souza JM.

Tech Hand Up Extrem Surg. 2019 Jul 23. doi: 10.1097/BTH.0000000000000258. [Epub ahead of print]

PMID:
31343593
5.

Low Revision Rates at 10 years for Metal on Metal Hip Implants in a Military Population.

Slaven SE, Richards JT, Wade SM, Saxena SK, Vanier AT, Cody JP.

Mil Med. 2019 Feb 27. pii: usz019. doi: 10.1093/milmed/usz019. [Epub ahead of print]

PMID:
30811533
6.

Proximal Femur Hounsfield Units on CT Colonoscopy Correlate With Dual-energy X-ray Absorptiometry.

Christensen DL, Nappo KE, Wolfe JA, Wade SM, Brooks DI, Potter BK, Forsberg JA, Tintle SM.

Clin Orthop Relat Res. 2019 Apr;477(4):850-860. doi: 10.1097/CORR.0000000000000480.

PMID:
30811362
7.

Infected Spinal Wounds Should be Closed With Nonbarbed Monofilament Suture.

Fredericks DR Jr, Slaven SE, Wade SM, Richards JT, Dingle ME, Wagner SC.

Clin Spine Surg. 2019 Jan 23. doi: 10.1097/BSD.0000000000000774. [Epub ahead of print] No abstract available.

PMID:
30681415
8.

Association of synovial tissue polyfunctional T-cells with DAPSA in psoriatic arthritis.

Wade SM, Canavan M, McGarry T, Low C, Wade SC, Mullan RH, Veale DJ, Fearon U.

Ann Rheum Dis. 2019 Mar;78(3):350-354. doi: 10.1136/annrheumdis-2018-214138. Epub 2019 Jan 9.

9.

Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis.

Canavan M, Walsh AM, Bhargava V, Wade SM, McGarry T, Marzaioli V, Moran B, Biniecka M, Convery H, Wade S, Orr C, Mullan R, Fletcher JM, Nagpal S, Veale DJ, Fearon U.

JCI Insight. 2018 Dec 6;3(23). pii: 95228. doi: 10.1172/jci.insight.95228.

10.

Is the Use of Intraoperative Corticosteroids Harmful in Lumbar Decompression Surgery?

Wade SM, Fredericks DR, Slaven SE, Dingle ME, Wagner SC.

Clin Spine Surg. 2019 Dec;32(10):409-411. doi: 10.1097/BSD.0000000000000741. No abstract available.

PMID:
30451784
11.

Altered metabolic pathways regulate synovial inflammation in rheumatoid arthritis.

Fearon U, Hanlon MM, Wade SM, Fletcher JM.

Clin Exp Immunol. 2019 Aug;197(2):170-180. doi: 10.1111/cei.13228. Epub 2018 Nov 11. Review.

PMID:
30357805
12.

Are Epidural Steroid Injections Beneficial for Patients With Degenerative Lumbar Spondylolisthesis?

Fredericks DR Jr, Wade SM, Pisano AJ, Bharmal H.

Clin Spine Surg. 2019 Oct;32(8):309-312. doi: 10.1097/BSD.0000000000000724. No abstract available.

PMID:
30285970
13.

Physical Therapy After Lumbar Spinal Fusion is Necessary to Optimize Patient Outcomes.

Mombell K, Perry N, Wade SM, Fredericks D, Glassman D, Morrissey P.

Clin Spine Surg. 2019 Jul;32(6):223-225. doi: 10.1097/BSD.0000000000000707. No abstract available.

PMID:
30192244
14.

Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B.

Wade SM, Trenkmann M, McGarry T, Canavan M, Marzaioli V, Wade SC, Veale DJ, Fearon U.

J Autoimmun. 2019 Jan;96:86-93. doi: 10.1016/j.jaut.2018.08.008. Epub 2018 Sep 1.

15.

Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis.

Conway R, O'Neill L, McCarthy GM, Murphy CC, Fabre A, Kennedy S, Veale DJ, Wade SM, Fearon U, Molloy ES.

Ann Rheum Dis. 2018 Dec;77(12):1815-1824. doi: 10.1136/annrheumdis-2018-213488. Epub 2018 Aug 10.

PMID:
30097452
16.

A Combined Distal Tibial Turn-up Plasty and Intercalary Calcaneal Osteocutaneous Fillet Flap for Salvage of a Transtibial Amputation: A Case Report.

Wade SM, Harrington C, Fleming M, Potter BK.

JBJS Case Connect. 2017 Oct-Dec;7(4):e91. doi: 10.2106/JBJS.CC.16.00255.

PMID:
29286974
17.

Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.

Haak AJ, Appleton KM, Lisabeth EM, Misek SA, Ji Y, Wade SM, Bell JL, Rockwell CE, Airik M, Krook MA, Larsen SD, Verhaegen M, Lawlor ER, Neubig RR.

Mol Cancer Ther. 2017 Jan;16(1):193-204. doi: 10.1158/1535-7163.MCT-16-0482. Epub 2016 Nov 11.

18.

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks.

Evelyn CR, Lisabeth EM, Wade SM, Haak AJ, Johnson CN, Lawlor ER, Neubig RR.

Microarrays (Basel). 2016 May 28;5(2). pii: E13. doi: 10.3390/microarrays5020013.

19.

Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed.

Hurwitz HI, Uppal N, Wagner SA, Bendell JC, Beck JT, Wade SM 3rd, Nemunaitis JJ, Stella PJ, Pipas JM, Wainberg ZA, Manges R, Garrett WM, Hunter DS, Clark J, Leopold L, Sandor V, Levy RS.

J Clin Oncol. 2015 Dec 1;33(34):4039-47. doi: 10.1200/JCO.2015.61.4578. Epub 2015 Sep 8.

20.

Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors.

Blazer LL, Storaska AJ, Jutkiewicz EM, Turner EM, Calcagno M, Wade SM, Wang Q, Huang XP, Traynor JR, Husbands SM, Morari M, Neubig RR.

ACS Chem Neurosci. 2015 Jun 17;6(6):911-9. doi: 10.1021/acschemneuro.5b00063. Epub 2015 Apr 20.

PMID:
25844489
21.

Conditional disruption of interactions between Gαi2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury.

Parra S, Huang X, Charbeneau RA, Wade SM, Kaur K, Rorabaugh BR, Neubig RR.

BMC Pharmacol Toxicol. 2014 Jun 5;15:29. doi: 10.1186/2050-6511-15-29.

22.

How prepared are college freshmen athletes for the rigors of college strength and conditioning? A survey of college strength and conditioning coaches.

Wade SM, Pope ZC, Simonson SR.

J Strength Cond Res. 2014 Oct;28(10):2746-53. doi: 10.1519/JSC.0000000000000473.

PMID:
24714539
23.

Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assay.

Storaska AJ, Mei JP, Wu M, Li M, Wade SM, Blazer LL, Sjögren B, Hopkins CR, Lindsley CW, Lin Z, Babcock JJ, McManus OB, Neubig RR.

Cell Signal. 2013 Dec;25(12):2848-55. doi: 10.1016/j.cellsig.2013.09.007. Epub 2013 Sep 14.

24.

Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway.

Bell JL, Haak AJ, Wade SM, Sun Y, Neubig RR, Larsen SD.

Beilstein J Org Chem. 2013 May 21;9:966-73. doi: 10.3762/bjoc.9.111. Print 2013.

25.

Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics.

Jovic A, Wade SM, Neubig RR, Linderman JJ, Takayama S.

Integr Biol (Camb). 2013 Jul 24;5(7):932-9. doi: 10.1039/c3ib40032h. Epub 2013 Jun 4.

26.

Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents.

Bell JL, Haak AJ, Wade SM, Kirchhoff PD, Neubig RR, Larsen SD.

Bioorg Med Chem Lett. 2013 Jul 1;23(13):3826-32. doi: 10.1016/j.bmcl.2013.04.080. Epub 2013 May 7.

27.

Gαi2 signaling: friend or foe in cardiac injury and heart failure?

Kaur K, Parra S, Chen R, Charbeneau RA, Wade SM, Jay PY, Neubig RR.

Naunyn Schmiedebergs Arch Pharmacol. 2012 May;385(5):443-53. doi: 10.1007/s00210-011-0705-z. Epub 2012 Mar 14.

28.

Hi-Fi transmission of periodic signals amid cell-to-cell variability.

Jovic A, Wade SM, Miyawaki A, Neubig RR, Linderman JJ, Takayama S.

Mol Biosyst. 2011 Jul;7(7):2238-44. doi: 10.1039/c1mb05031a. Epub 2011 May 11.

29.

Phase-locked signals elucidate circuit architecture of an oscillatory pathway.

Jovic A, Howell B, Cote M, Wade SM, Mehta K, Miyawaki A, Neubig RR, Linderman JJ, Takayama S.

PLoS Comput Biol. 2010 Dec 23;6(12):e1001040. doi: 10.1371/journal.pcbi.1001040.

30.

Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423.

Evelyn CR, Bell JL, Ryu JG, Wade SM, Kocab A, Harzdorf NL, Showalter HD, Neubig RR, Larsen SD.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):665-72. doi: 10.1016/j.bmcl.2009.11.056. Epub 2009 Nov 18.

31.

CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling.

Evelyn CR, Wade SM, Wang Q, Wu M, Iñiguez-Lluhí JA, Merajver SD, Neubig RR.

Mol Cancer Ther. 2007 Aug;6(8):2249-60.

32.

Capillary electrophoresis assay for G protein-coupled receptor-mediated GTPase activity.

Jameson EE, Pei J, Wade SM, Neubig RR, Milligan G, Kennedy RT.

Anal Chem. 2007 Feb 1;79(3):1158-63.

PMID:
17263349
33.

A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

Zhong H, Wade SM, Woolf PJ, Linderman JJ, Traynor JR, Neubig RR.

J Biol Chem. 2003 Feb 28;278(9):7278-84. Epub 2002 Nov 21.

34.

Mutagenesis and peptide analysis of the DRY motif in the alpha2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors.

Chung DA, Wade SM, Fowler CB, Woods DD, Abada PB, Mosberg HI, Neubig RR.

Biochem Biophys Res Commun. 2002 May 17;293(4):1233-41.

PMID:
12054508
35.

Inverse agonist activity at the alpha(2A)-adrenergic receptor.

Wade SM, Lan K, Moore DJ, Neubig RR.

Mol Pharmacol. 2001 Mar;59(3):532-42.

PMID:
11179449
37.

G(i) activator region of alpha(2A)-adrenergic receptors: distinct basic residues mediate G(i) versus G(s) activation.

Wade SM, Lim WK, Lan KL, Chung DA, Nanamori M, Neubig RR.

Mol Pharmacol. 1999 Nov;56(5):1005-13.

PMID:
10531407
38.

Cotransfection of second and third intracellular loop fragments inhibit angiotensin AT1a receptor activation of phospholipase C in HEK-293 cells.

Thompson JB, Wade SM, Harrison JK, Salafranca MN, Neubig RR.

J Pharmacol Exp Ther. 1998 Apr;285(1):216-22.

PMID:
9536013
39.

Modulation of K+ and Ca2+ currents in cultured neurons by an angiotensin II type 1a receptor peptide.

Zhu M, Neubig RR, Wade SM, Posner P, Gelband CH, Sumners C.

Am J Physiol. 1997 Sep;273(3 Pt 1):C1040-8.

PMID:
9316425
40.
41.
42.
43.

p-[125I]iodoclonidine is a partial agonist at the alpha 2-adrenergic receptor.

Gerhardt MA, Wade SM, Neubig RR.

Mol Pharmacol. 1990 Aug;38(2):214-21.

PMID:
1974694
44.

Immunity to leprosy. IV. Murine T-cell proliferative responses to mycobacteria.

Douglas-Jones AG, Wade SM, Vaughan RH, Watson JD.

Int J Lepr Other Mycobact Dis. 1986 Sep;54(3):367-79.

PMID:
3528344
45.

Mammalian host- and fluid-mediated mutagenicity assays of captan and streptozotocin in Salmonella typhimurium.

Ficsor G, Bordás S, Wade SM, Muthiani E, Wertz GF, Zimmer DM.

Mutat Res. 1977;48(1):1-15.

PMID:
138085
46.

Therapeutic agent. No. 2,452,813.

WADE SM.

J Pat Off Soc. 1948;108:Unknown. No abstract available.

PMID:
18098865

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