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Items: 1 to 50 of 263

1.

MRI method for labeling and imaging decellularized extracellular matrix scaffolds for tissue engineering.

Szulc DA, Ahmadipour M, Aoki FG, Waddell TK, Karoubi G, Cheng HM.

Magn Reson Med. 2019 Nov 14. doi: 10.1002/mrm.28072. [Epub ahead of print]

PMID:
31729091
2.

Prevention of viral transmission during lung transplantation with hepatitis C-viraemic donors: an open-label, single-centre, pilot trial.

Cypel M, Feld JJ, Galasso M, Pinto Ribeiro RV, Marks N, Kuczynski M, Kumar D, Bahinskaya I, Bagnato VS, Kurachi C, Slutsky AS, Yeung JC, Donahoe L, de Perrot M, Yasufuku K, Pierre A, Binnie M, Chaparro C, Martinu T, Chen M, Tikkanen J, Chow CW, Sidhu A, Waddell TK, Keshavjee S, Singer LG, Humar A.

Lancet Respir Med. 2019 Oct 9. pii: S2213-2600(19)30268-1. doi: 10.1016/S2213-2600(19)30268-1. [Epub ahead of print]

PMID:
31606437
3.

Normothermic ex vivo lung perfusion: Does the indication impact organ utilization and patient outcomes after transplantation?

Cypel M, Yeung JC, Donahoe L, Chen M, Zamel R, Hoetzenecker K, Yasufuku K, de Perrot M, Pierre AF, Waddell TK, Keshavjee S.

J Thorac Cardiovasc Surg. 2019 Sep 9. pii: S0022-5223(19)31732-5. doi: 10.1016/j.jtcvs.2019.06.123. [Epub ahead of print]

PMID:
31606173
4.

Long-term Outcomes of Lung Transplant With Ex Vivo Lung Perfusion.

Divithotawela C, Cypel M, Martinu T, Singer LG, Binnie M, Chow CW, Chaparro C, Waddell TK, de Perrot M, Pierre A, Yasufuku K, Yeung JC, Donahoe L, Keshavjee S, Tikkanen JM.

JAMA Surg. 2019 Oct 9. doi: 10.1001/jamasurg.2019.4079. [Epub ahead of print]

PMID:
31596484
5.

Preoperative ECMO and plasmapheresis for urgent pulmonary endarterectomy in HIT positive patient.

Tahiri M, Bykova A, Dunne B, Barth D, Donahoe L, Waddell TK, McRae K, Slinger P, Granton J, de Perrot M.

Ann Thorac Surg. 2019 Oct 4. pii: S0003-4975(19)31484-5. doi: 10.1016/j.athoracsur.2019.08.092. [Epub ahead of print]

PMID:
31589861
6.

Mesenchymal stromal cell therapy during ex vivo lung perfusion ameliorates ischemia-reperfusion injury in lung transplantation.

Nakajima D, Watanabe Y, Ohsumi A, Pipkin M, Chen M, Mordant P, Kanou T, Saito T, Lam R, Coutinho R, Caldarone L, Juvet S, Martinu T, Iyer RK, Davies JE, Hwang DM, Waddell TK, Cypel M, Liu M, Keshavjee S.

J Heart Lung Transplant. 2019 Nov;38(11):1214-1223. doi: 10.1016/j.healun.2019.07.006. Epub 2019 Jul 26.

PMID:
31474491
7.

De-epithelialization of porcine tracheal allografts as an approach for tracheal tissue engineering.

Aoki FG, Varma R, Marin-Araujo AE, Lee H, Soleas JP, Li AH, Soon K, Romero D, Moriya HT, Haykal S, Amon C, Waddell TK, Karoubi G.

Sci Rep. 2019 Aug 19;9(1):12034. doi: 10.1038/s41598-019-48450-4.

8.

Conversion of human and mouse fibroblasts into lung-like epithelial cells.

Wong AP, Shojaie S, Liang Q, Xia S, Di Paola M, Ahmadi S, Bilodeau C, Garner J, Post M, Duchesneau P, Waddell TK, Bear CE, Nagy A, Rossant J.

Sci Rep. 2019 Jun 21;9(1):9027. doi: 10.1038/s41598-019-45195-y.

9.

Donor prone positioning protects lungs from injury during warm ischemia.

Watanabe Y, Galasso M, Watanabe T, Ali A, Qaqish R, Nakajima D, Taniguchi Y, Pipkin M, Caldarone L, Chen M, Kanou T, Summers C, Ramadan K, Zhang Y, Chan H, Waddell TK, Liu M, Keshavjee S, Del Sorbo L, Cypel M.

Am J Transplant. 2019 Oct;19(10):2746-2755. doi: 10.1111/ajt.15363. Epub 2019 Apr 25.

PMID:
30887696
10.

3D Models in the Diagnosis of Subglottic Airway Stenosis.

Hoetzenecker K, Chan HHL, Frommlet F, Schweiger T, Keshavjee S, Waddell TK, Klepetko W, Irish JC, Yasufuku K.

Ann Thorac Surg. 2019 Jun;107(6):1860-1865. doi: 10.1016/j.athoracsur.2019.01.045. Epub 2019 Feb 27.

PMID:
30825452
11.

Near-infrared mapping with indocyanine green is associated with an increase in oncological margin length in minimally invasive segmentectomy.

Mehta M, Patel YS, Yasufuku K, Waddell TK, Shargall Y, Fahim C, Hanna WC.

J Thorac Cardiovasc Surg. 2019 May;157(5):2029-2035. doi: 10.1016/j.jtcvs.2018.12.099. Epub 2019 Jan 21.

PMID:
30803778
12.

CT-guided Microcoil Pulmonary Nodule Localization prior to Video-assisted Thoracoscopic Surgery: Diagnostic Utility and Recurrence-Free Survival.

Rodrigues JCL, Pierre AF, Hanneman K, Cabanero M, Kavanagh J, Waddell TK, Chung TB, Pakkal M, Keshavjee S, Cypel M, Yasufuku K, Nguyen ET.

Radiology. 2019 Apr;291(1):214-222. doi: 10.1148/radiol.2019181674. Epub 2019 Feb 5.

PMID:
30720402
13.

Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion.

Galasso M, Feld JJ, Watanabe Y, Pipkin M, Summers C, Ali A, Qaqish R, Chen M, Ribeiro RVP, Ramadan K, Pires L, Bagnato VS, Kurachi C, Cherepanov V, Moonen G, Gazzalle A, Waddell TK, Liu M, Keshavjee S, Wilson BC, Humar A, Cypel M.

Nat Commun. 2019 Jan 29;10(1):481. doi: 10.1038/s41467-018-08261-z.

14.

Metachronous or synchronous primary lung cancer in the era of computed tomography surveillance.

Wang Y, Yeung JC, Hanna WC, Allison F, Paul NS, Waddell TK, Cypel M, de Perrot ME, Yasufuku K, Keshavjee S, Pierre AF, Darling GE.

J Thorac Cardiovasc Surg. 2018 Oct 6. pii: S0022-5223(18)32556-X. doi: 10.1016/j.jtcvs.2018.09.052. [Epub ahead of print]

PMID:
30392946
15.

Porphyrin-High-Density Lipoprotein: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy.

Ujiie H, Ding L, Fan R, Kato T, Lee D, Fujino K, Kinoshita T, Lee CY, Waddell TK, Keshavjee S, Wilson BC, Zheng G, Chen J, Yasufuku K.

Ann Thorac Surg. 2019 Feb;107(2):369-377. doi: 10.1016/j.athoracsur.2018.08.053. Epub 2018 Oct 11.

PMID:
30316853
16.

Emergency department use is high after esophagectomy and feeding tube problems are the biggest culprit.

Kidane B, Kaaki S, Hirpara DH, Shen YC, Bassili A, Allison F, Waddell TK, Darling GE.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2340-2348. doi: 10.1016/j.jtcvs.2018.07.100. Epub 2018 Sep 7.

PMID:
30309674
17.

Optimal biomaterials for tracheal epithelial grafts: An in vitro systematic comparative analysis.

Varma R, Aoki FG, Soon K, Karoubi G, Waddell TK.

Acta Biomater. 2018 Nov;81:146-157. doi: 10.1016/j.actbio.2018.09.048. Epub 2018 Sep 27.

PMID:
30268918
18.

Interrupted reprogramming of alveolar type II cells induces progenitor-like cells that ameliorate pulmonary fibrosis.

Guo L, Karoubi G, Duchesneau P, Aoki FG, Shutova MV, Rogers I, Nagy A, Waddell TK.

NPJ Regen Med. 2018 Sep 4;3:14. doi: 10.1038/s41536-018-0052-5. eCollection 2018.

19.

Intraoperative extracorporeal support during lung transplantation in patients bridged with venovenous extracorporeal membrane oxygenation.

Hashimoto K, Hoetzenecker K, Yeung JC, Jeagal L, Donahoe L, Pierre A, de Perrot M, Yasufuku K, Waddell TK, Keshavjee S, Cypel M.

J Heart Lung Transplant. 2018 Dec;37(12):1418-1424. doi: 10.1016/j.healun.2018.07.003. Epub 2018 Sep 5.

PMID:
30193763
20.

The role of endobronchial ultrasound-guided transbronchial needle aspiration in stereotactic body radiation therapy for non-small cell lung cancer.

Hashimoto K, Daddi N, Giuliani M, Hope A, Le LW, Czarnecka K, Cypel M, Pierre A, de Perrot M, Darling G, Waddell TK, Keshavjee S, Yasufuku K.

Lung Cancer. 2018 Sep;123:1-6. doi: 10.1016/j.lungcan.2018.06.011. Epub 2018 Jun 11.

PMID:
30089578
21.

Medium and long-term emergency department utilization after oesophagectomy: a population-based analysis.

Kidane B, Jacob B, Gupta V, Peel J, Saskin R, Waddell TK, Darling GE.

Eur J Cardiothorac Surg. 2018 Oct 1;54(4):683-688. doi: 10.1093/ejcts/ezy155.

PMID:
29648637
22.

Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion.

Iskender I, Cypel M, Martinu T, Chen M, Sakamoto J, Kim H, Yu K, Lin H, Guan Z, Hashimoto K, Waddell TK, Liu M, Keshavjee S.

Transplantation. 2018 May;102(5):760-768. doi: 10.1097/TP.0000000000002140.

PMID:
29470355
23.

Towards donor lung recovery-gene expression changes during ex vivo lung perfusion of human lungs.

Yeung JC, Zamel R, Klement W, Bai XH, Machuca TN, Waddell TK, Liu M, Cypel M, Keshavjee S.

Am J Transplant. 2018 Jun;18(6):1518-1526. doi: 10.1111/ajt.14700. Epub 2018 Mar 30.

24.

Design of biomimetic substrates for long-term maintenance of alveolar epithelial cells.

Poon JCH, Liao Z, Suzuki T, Carleton MM, Soleas JP, Aitchison JS, Karoubi G, McGuigan AP, Waddell TK.

Biomater Sci. 2018 Jan 30;6(2):292-303. doi: 10.1039/c7bm00647k.

PMID:
29327014
25.

Extracorporeal life support as a bridge to lung transplantation-experience of a high-volume transplant center.

Hoetzenecker K, Donahoe L, Yeung JC, Azad S, Fan E, Ferguson ND, Del Sorbo L, de Perrot M, Pierre A, Yasufuku K, Singer L, Waddell TK, Keshavjee S, Cypel M.

J Thorac Cardiovasc Surg. 2018 Mar;155(3):1316-1328.e1. doi: 10.1016/j.jtcvs.2017.09.161. Epub 2017 Nov 22.

PMID:
29248282
26.

Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming.

Guo L, Karoubi G, Duchesneau P, Shutova MV, Sung HK, Tonge P, Bear C, Rogers I, Nagy A, Waddell TK.

Stem Cell Reports. 2017 Dec 12;9(6):1780-1795. doi: 10.1016/j.stemcr.2017.10.022. Epub 2017 Nov 30.

27.

Metabolic heterogeneity of idiopathic pulmonary fibrosis: a metabolomic study.

Zhao YD, Yin L, Archer S, Lu C, Zhao G, Yao Y, Wu L, Hsin M, Waddell TK, Keshavjee S, Granton J, de Perrot M.

BMJ Open Respir Res. 2017 Jun 5;4(1):e000183. doi: 10.1136/bmjresp-2017-000183. eCollection 2017.

28.

Development of a novel ex vivo porcine laparoscopic Heller myotomy and Nissen fundoplication training model (Toronto lap-Nissen simulator).

Ujiie H, Kato T, Hu HP, Bauer P, Patel P, Wada H, Lee D, Fujino K, Schieman C, Pierre A, Waddell TK, Keshavjee S, Darling GE, Yasufuku K.

J Thorac Dis. 2017 Jun;9(6):1517-1524. doi: 10.21037/jtd.2017.05.84.

29.

Higher M30 and high mobility group box 1 protein levels in ex vivo lung perfusate are associated with primary graft dysfunction after human lung transplantation.

Hashimoto K, Cypel M, Juvet S, Saito T, Zamel R, Machuca TN, Hsin M, Kim H, Waddell TK, Liu M, Keshavjee S.

J Heart Lung Transplant. 2017 Jun 21. pii: S1053-2498(17)31870-3. doi: 10.1016/j.healun.2017.06.005. [Epub ahead of print]

PMID:
28689646
30.

Combined lung-liver-pancreas transplantation in a recipient with cystic fibrosis.

Barbas AS, Dib MJ, Al-Adra DP, Goldaracena N, Sapisochin G, Waddell TK, Keshavjee S, Selzner N, Chaparro C, Cattral MS.

J Cyst Fibros. 2018 Jan;17(1):e1-e4. doi: 10.1016/j.jcf.2017.05.004. Epub 2017 May 23.

PMID:
28549610
31.

A novel minimally invasive near-infrared thoracoscopic localization technique of small pulmonary nodules: A phase I feasibility trial.

Ujiie H, Kato T, Hu HP, Patel P, Wada H, Fujino K, Weersink R, Nguyen E, Cypel M, Pierre A, de Perrot M, Darling G, Waddell TK, Keshavjee S, Yasufuku K.

J Thorac Cardiovasc Surg. 2017 Aug;154(2):702-711. doi: 10.1016/j.jtcvs.2017.03.140. Epub 2017 Apr 13.

32.

Skin-derived precursors from human subjects with Type 2 diabetes yield dysfunctional vascular smooth muscle cells.

Steinbach SK, Yau TM, Ouzounian M, Abdel-Qadir H, Chandy M, Waddell TK, Husain M.

Clin Sci (Lond). 2017 Jul 5;131(15):1801-1814. doi: 10.1042/CS20170239. Print 2017 Aug 1.

PMID:
28424290
33.

Cost-effectiveness of mediastinal lymph node staging in non-small cell lung cancer.

Czarnecka-Kujawa K, Rochau U, Siebert U, Atenafu E, Darling G, Waddell TK, Pierre A, De Perrot M, Cypel M, Keshavjee S, Yasufuku K.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1567-1578. doi: 10.1016/j.jtcvs.2016.12.048. Epub 2017 Feb 9.

34.

Invasive Mediastinal Staging Guideline Concordance.

Bendzsak A, Waddell TK, Yasufuku K, Keshavjee S, de Perrot M, Cypel M, Pierre AF, Darling GE.

Ann Thorac Surg. 2017 Jun;103(6):1736-1741. doi: 10.1016/j.athoracsur.2016.12.010. Epub 2017 Mar 3.

PMID:
28262300
35.

High Risk for Thoracotomy but not Thoracoscopic Lobectomy.

Donahoe LL, de Valence M, Atenafu EG, Hanna WC, Waddell TK, Pierre AF, Yasufuku K, de Perrot M, Cypel M, Keshavjee S, Darling GE.

Ann Thorac Surg. 2017 Jun;103(6):1730-1735. doi: 10.1016/j.athoracsur.2016.11.076. Epub 2017 Mar 3.

PMID:
28262299
36.

Partial Restoration of CFTR Function in cftr-Null Mice following Targeted Cell Replacement Therapy.

Duchesneau P, Besla R, Derouet MF, Guo L, Karoubi G, Silberberg A, Wong AP, Waddell TK.

Mol Ther. 2017 Mar 1;25(3):654-665. doi: 10.1016/j.ymthe.2016.11.018. Epub 2017 Feb 8.

37.

Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model.

Machuca TN, Cypel M, Bonato R, Yeung JC, Chun YM, Juvet S, Guan Z, Hwang DM, Chen M, Saito T, Harmantas C, Davidson BL, Waddell TK, Liu M, Keshavjee S.

Hum Gene Ther. 2017 Sep;28(9):757-765. doi: 10.1089/hum.2016.070. Epub 2017 Jan 4.

PMID:
28052693
38.

Lung Lavage and Surfactant Replacement During Ex Vivo Lung Perfusion for Treatment of Gastric Acid Aspiration-Induced Donor Lung Injury.

Nakajima D, Liu M, Ohsumi A, Kalaf R, Iskender I, Hsin M, Kanou T, Chen M, Baer B, Coutinho R, Maahs L, Behrens P, Azad S, Martinu T, Waddell TK, Lewis JF, Post M, Veldhuizen RAW, Cypel M, Keshavjee S.

J Heart Lung Transplant. 2017 May;36(5):577-585. doi: 10.1016/j.healun.2016.11.010. Epub 2016 Dec 1.

PMID:
28041954
39.

Soluble Adhesion Molecules During Ex Vivo Lung Perfusion Are Associated With Posttransplant Primary Graft Dysfunction.

Hashimoto K, Cypel M, Kim H, Machuca TN, Nakajima D, Chen M, Hsin MK, Zamel R, Azad S, Waddell TK, Liu M, Keshavjee S.

Am J Transplant. 2017 May;17(5):1396-1404. doi: 10.1111/ajt.14160. Epub 2017 Feb 1.

40.

Surgery and Surgical Consult Rates for Early Stage Lung Cancer in Ontario: A Population-Based Study.

Bendzsak AM, Waddell TK, Urbach DR, Darling GE.

Ann Thorac Surg. 2017 Mar;103(3):906-910. doi: 10.1016/j.athoracsur.2016.09.025. Epub 2016 Dec 7.

PMID:
27939011
41.

SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.

Kim BR, Van de Laar E, Cabanero M, Tarumi S, Hasenoeder S, Wang D, Virtanen C, Suzuki T, Bandarchi B, Sakashita S, Pham NA, Lee S, Keshavjee S, Waddell TK, Tsao MS, Moghal N.

PLoS Biol. 2016 Nov 23;14(11):e1002581. doi: 10.1371/journal.pbio.1002581. eCollection 2016 Nov.

42.

Successful Lung Transplantation From Hepatitis C Positive Donor to Seronegative Recipient.

Khan B, Singer LG, Lilly LB, Chaparro C, Martinu T, Juvet S, Pipkin M, Waddell TK, Keshavjee S, Humar A, Cypel M.

Am J Transplant. 2017 Apr;17(4):1129-1131. doi: 10.1111/ajt.14137. Epub 2017 Jan 16.

43.

Outcomes after transplantation of lungs preserved for more than 12 h: a retrospective study.

Yeung JC, Krueger T, Yasufuku K, de Perrot M, Pierre AF, Waddell TK, Singer LG, Keshavjee S, Cypel M.

Lancet Respir Med. 2017 Feb;5(2):119-124. doi: 10.1016/S2213-2600(16)30323-X. Epub 2016 Nov 18.

PMID:
27866861
44.

Mesenchymal stem cell treatment is associated with decreased perfusate concentration of interleukin-8 during ex vivo perfusion of donor lungs after 18-hour preservation.

Mordant P, Nakajima D, Kalaf R, Iskender I, Maahs L, Behrens P, Coutinho R, Iyer RK, Davies JE, Cypel M, Liu M, Waddell TK, Keshavjee S.

J Heart Lung Transplant. 2016 Oct;35(10):1245-1254. doi: 10.1016/j.healun.2016.04.017. Epub 2016 May 6.

PMID:
27444694
45.

Evaluation of a New Ultrasound Thoracoscope for Localization of Lung Nodules in Ex Vivo Human Lungs.

Ujiie H, Kato T, Hu HP, Hasan S, Patel P, Wada H, Lee D, Fujino K, Hwang DM, Cypel M, de Perrot M, Pierre A, Darling G, Waddell TK, Keshavjee S, Yasufuku K.

Ann Thorac Surg. 2017 Mar;103(3):926-934. doi: 10.1016/j.athoracsur.2016.08.031. Epub 2016 Oct 17.

PMID:
27765176
46.

CT-guided microcoil VATS resection of lung nodules: a single-centre experience and review of the literature.

Donahoe LL, Nguyen ET, Chung TB, Kha LC, Cypel M, Darling GE, de Perrot M, Keshavjee S, Pierre AF, Waddell TK, Yasufuku K.

J Thorac Dis. 2016 Aug;8(8):1986-94. doi: 10.21037/jtd.2016.06.74.

47.

The Use of Robotic-Assisted Thoracic Surgery for Lung Resection: A Comprehensive Systematic Review.

Agzarian J, Fahim C, Shargall Y, Yasufuku K, Waddell TK, Hanna WC.

Semin Thorac Cardiovasc Surg. 2016 Spring;28(1):182-92. doi: 10.1053/j.semtcvs.2016.01.004. Epub 2016 Feb 9. Review.

PMID:
27568159
48.

Importance of left atrial pressure during ex vivo lung perfusion.

Linacre V, Cypel M, Machuca T, Nakajima D, Hashimoto K, Zamel R, Chen M, Iskender I, Dos Santos P, Waddell TK, Liu M, Keshavjee S.

J Heart Lung Transplant. 2016 Jun;35(6):808-14. doi: 10.1016/j.healun.2016.02.008. Epub 2016 Mar 10.

PMID:
27160496
49.

Human α1-antitrypsin improves early post-transplant lung function: Pre-clinical studies in a pig lung transplant model.

Iskender I, Sakamoto J, Nakajima D, Lin H, Chen M, Kim H, Guan Z, Del Sorbo L, Hwang D, Waddell TK, Cypel M, Keshavjee S, Liu M.

J Heart Lung Transplant. 2016 Jul;35(7):913-21. doi: 10.1016/j.healun.2016.03.006. Epub 2016 Mar 23.

PMID:
27095003
50.

A window of opportunity study of potential tumor and soluble biomarkers of response to preoperative erlotinib in early stage non-small cell lung cancer.

Sacher AG, Le LW, Lara-Guerra H, Waddell TK, Sakashita S, Chen Z, Kim L, Zhang T, Kamel-Reid S, Salvarrey A, Darling G, Yasufuku K, Keshavjee S, de Perrot M, Shepherd FA, Liu G, Tsao MS, Leighl NB.

Oncotarget. 2016 May 3;7(18):25632-9. doi: 10.18632/oncotarget.8350.

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