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Items: 28

1.

Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.

Kumar P, Agarwal PK, Waddell MB, Mittag T, Serpersu EH, Cuneo MJ.

Angew Chem Int Ed Engl. 2019 Nov 4;58(45):16260-16266. doi: 10.1002/anie.201908535. Epub 2019 Sep 24. Review.

PMID:
31515870
2.

Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.

Tsytlonok M, Sanabria H, Wang Y, Felekyan S, Hemmen K, Phillips AH, Yun MK, Waddell MB, Park CG, Vaithiyalingam S, Iconaru L, White SW, Tompa P, Seidel CAM, Kriwacki R.

Nat Commun. 2019 Apr 11;10(1):1676. doi: 10.1038/s41467-019-09446-w.

3.

The phage T4 MotA transcription factor contains a novel DNA binding motif that specifically recognizes modified DNA.

Cuypers MG, Robertson RM, Knipling L, Waddell MB, Moon K, Hinton DM, White SW.

Nucleic Acids Res. 2018 Jun 1;46(10):5308-5318. doi: 10.1093/nar/gky292.

4.

Alteration of RNA Splicing by Small-Molecule Inhibitors of the Interaction between NHP2L1 and U4.

Diouf B, Lin W, Goktug A, Grace CRR, Waddell MB, Bao J, Shao Y, Heath RJ, Zheng JJ, Shelat AA, Relling MV, Chen T, Evans WE.

SLAS Discov. 2018 Feb;23(2):164-173. doi: 10.1177/2472555217735035. Epub 2017 Oct 6.

5.

Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins.

Danelius E, Pettersson M, Bred M, Min J, Waddell MB, Guy RK, Grøtli M, Erdelyi M.

Org Biomol Chem. 2016 Nov 8;14(44):10386-10393.

PMID:
27731454
6.

Structure and mechanism of the phage T4 recombination mediator protein UvsY.

Gajewski S, Waddell MB, Vaithiyalingam S, Nourse A, Li Z, Woetzel N, Alexander N, Meiler J, White SW.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3275-80. doi: 10.1073/pnas.1519154113. Epub 2016 Mar 7.

7.

MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression.

Paugh SW, Coss DR, Bao J, Laudermilk LT, Grace CR, Ferreira AM, Waddell MB, Ridout G, Naeve D, Leuze M, LoCascio PF, Panetta JC, Wilkinson MR, Pui CH, Naeve CW, Uberbacher EC, Bonten EJ, Evans WE.

PLoS Comput Biol. 2016 Feb 4;12(2):e1004744. doi: 10.1371/journal.pcbi.1004744. eCollection 2016 Feb.

8.

Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction.

Pettersson M, Quant M, Min J, Iconaru L, Kriwacki RW, Waddell MB, Guy RK, Luthman K, Grøtli M.

PLoS One. 2015 Oct 1;10(10):e0137867. doi: 10.1371/journal.pone.0137867. eCollection 2015.

9.

The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

Yun MK, Hoagland D, Kumar G, Waddell MB, Rock CO, Lee RE, White SW.

Bioorg Med Chem. 2014 Apr 1;22(7):2157-65. doi: 10.1016/j.bmc.2014.02.022. Epub 2014 Feb 25.

10.

Architecture of the bacteriophage T4 activator MotA/promoter DNA interaction during sigma appropriation.

Hsieh ML, James TD, Knipling L, Waddell MB, White S, Hinton DM.

J Biol Chem. 2013 Sep 20;288(38):27607-18. doi: 10.1074/jbc.M113.475434. Epub 2013 Jul 31.

11.

A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes.

Zhang J, Loyd MR, Randall MS, Waddell MB, Kriwacki RW, Ney PA.

Autophagy. 2012 Sep;8(9):1325-32. doi: 10.4161/auto.20764. Epub 2012 Aug 21.

12.

Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface.

Duda DM, Olszewski JL, Tron AE, Hammel M, Lambert LJ, Waddell MB, Mittag T, DeCaprio JA, Schulman BA.

Mol Cell. 2012 Aug 10;47(3):371-82. doi: 10.1016/j.molcel.2012.05.044. Epub 2012 Jun 28.

13.

Catalysis and sulfa drug resistance in dihydropteroate synthase.

Yun MK, Wu Y, Li Z, Zhao Y, Waddell MB, Ferreira AM, Lee RE, Bashford D, White SW.

Science. 2012 Mar 2;335(6072):1110-4. doi: 10.1126/science.1214641.

14.

Mechanism of cell cycle entry mediated by the intrinsically disordered protein p27(Kip1).

Ou L, Waddell MB, Kriwacki RW.

ACS Chem Biol. 2012 Apr 20;7(4):678-82. doi: 10.1021/cb200487h. Epub 2012 Feb 3.

15.

Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.

Zhuang M, Calabrese MF, Liu J, Waddell MB, Nourse A, Hammel M, Miller DJ, Walden H, Duda DM, Seyedin SN, Hoggard T, Harper JW, White KP, Schulman BA.

Mol Cell. 2009 Oct 9;36(1):39-50. doi: 10.1016/j.molcel.2009.09.022.

16.

A global benchmark study using affinity-based biosensors.

Rich RL, Papalia GA, Flynn PJ, Furneisen J, Quinn J, Klein JS, Katsamba PS, Waddell MB, Scott M, Thompson J, Berlier J, Corry S, Baltzinger M, Zeder-Lutz G, Schoenemann A, Clabbers A, Wieckowski S, Murphy MM, Page P, Ryan TE, Duffner J, Ganguly T, Corbin J, Gautam S, Anderluh G, Bavdek A, Reichmann D, Yadav SP, Hommema E, Pol E, Drake A, Klakamp S, Chapman T, Kernaghan D, Miller K, Schuman J, Lindquist K, Herlihy K, Murphy MB, Bohnsack R, Andrien B, Brandani P, Terwey D, Millican R, Darling RJ, Wang L, Carter Q, Dotzlaf J, Lopez-Sagaseta J, Campbell I, Torreri P, Hoos S, England P, Liu Y, Abdiche Y, Malashock D, Pinkerton A, Wong M, Lafer E, Hinck C, Thompson K, Primo CD, Joyce A, Brooks J, Torta F, Bagge Hagel AB, Krarup J, Pass J, Ferreira M, Shikov S, Mikolajczyk M, Abe Y, Barbato G, Giannetti AM, Krishnamoorthy G, Beusink B, Satpaev D, Tsang T, Fang E, Partridge J, Brohawn S, Horn J, Pritsch O, Obal G, Nilapwar S, Busby B, Gutierrez-Sanchez G, Gupta RD, Canepa S, Witte K, Nikolovska-Coleska Z, Cho YH, D'Agata R, Schlick K, Calvert R, Munoz EM, Hernaiz MJ, Bravman T, Dines M, Yang MH, Puskas A, Boni E, Li J, Wear M, Grinberg A, Baardsnes J, Dolezal O, Gainey M, Anderson H, Peng J, Lewis M, Spies P, Trinh Q, Bibikov S, Raymond J, Yousef M, Chandrasekaran V, Feng Y, Emerick A, Mundodo S, Guimaraes R, McGirr K, Li YJ, Hughes H, Mantz H, Skrabana R, Witmer M, Ballard J, Martin L, Skladal P, Korza G, Laird-Offringa I, Lee CS, Khadir A, Podlaski F, Neuner P, Rothacker J, Rafique A, Dankbar N, Kainz P, Gedig E, Vuyisich M, Boozer C, Ly N, Toews M, Uren A, Kalyuzhniy O, Lewis K, Chomey E, Pak BJ, Myszka DG.

Anal Biochem. 2009 Mar 15;386(2):194-216. doi: 10.1016/j.ab.2008.11.021. Epub 2008 Nov 27.

17.

Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.

Souphron J, Waddell MB, Paydar A, Tokgöz-Gromley Z, Roussel MF, Schulman BA.

Biochemistry. 2008 Aug 26;47(34):8961-9. doi: 10.1021/bi800604c. Epub 2008 Jul 25.

18.

Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a non-covalent ubiquitin-like protein-E2 complex as a platform for selective interactions within a SUMO pathway.

Duda DM, van Waardenburg RC, Borg LA, McGarity S, Nourse A, Waddell MB, Bjornsti MA, Schulman BA.

J Mol Biol. 2007 Jun 8;369(3):619-30. Epub 2007 Apr 10.

19.

Thermodynamic benchmark study using Biacore technology.

Navratilova I, Papalia GA, Rich RL, Bedinger D, Brophy S, Condon B, Deng T, Emerick AW, Guan HW, Hayden T, Heutmekers T, Hoorelbeke B, McCroskey MC, Murphy MM, Nakagawa T, Parmeggiani F, Qin X, Rebe S, Tomasevic N, Tsang T, Waddell MB, Zhang FF, Leavitt S, Myszka DG.

Anal Biochem. 2007 May 1;364(1):67-77. Epub 2007 Jan 26.

PMID:
17362870
20.

Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases.

Grimmler M, Wang Y, Mund T, Cilensek Z, Keidel EM, Waddell MB, Jäkel H, Kullmann M, Kriwacki RW, Hengst L.

Cell. 2007 Jan 26;128(2):269-80.

21.

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.

Huang DT, Paydar A, Zhuang M, Waddell MB, Holton JM, Schulman BA.

Mol Cell. 2005 Feb 4;17(3):341-50.

22.

The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein.

Zhao C, Beaudenon SL, Kelley ML, Waddell MB, Yuan W, Schulman BA, Huibregtse JM, Krug RM.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7578-82. Epub 2004 May 6.

23.

Comparative efficacy of certain South American Aëdes and Haemagogus mosquitoes as laboratory vectors of yellow fever.

WADDELL MB.

Am J Trop Med Hyg. 1949 Jul;29(4):567-75. No abstract available.

PMID:
18153054
24.

Haemogogus capricornii Lutz as a laboratory vector of yellow fever.

WADDELL MB, KUMM HW.

Am J Trop Med Hyg. 1948 Mar;28(2):247-52. No abstract available.

PMID:
18858024
27.

A specific blood group O substance.

MORGAN WT, WADDELL MB.

Br J Exp Pathol. 1945 Dec;26:387-96. No abstract available.

28.

The routine estimation of haemoglobin as oxyhaemoglobin.

Bell GH, Chambers JW, Waddell MB.

Biochem J. 1945;39(1):60-3. No abstract available.

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