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Items: 1 to 50 of 71

1.

Protein S multimers are generated in vitro and affect protein S structure-function analyses.

Seré KM, Willems GM, Rosing J, Hackeng TM.

Semin Hematol. 2006 Jan;43(1 Suppl 1):S111-20.

PMID:
16427377
2.

Anti-prothrombin IgG from patients with anti-phospholipid antibodies inhibits the inactivation of factor Va by activated protein C.

Galli M, Willems GM, Rosing J, Janssen RM, Govers-Riemslag JW, Comfurius P, Barbui T, Zwaal RF, Bevers EM.

Br J Haematol. 2005 Apr;129(2):240-7.

PMID:
15813852
3.

The antiphospholipid/cofactor syndrome: results of routine screening for antibodies to beta2-GPI upon suspicion of the antiphospholipid syndrome.

Damoiseaux J, Wijffels M, Willems GM, Bevers EM, Spaanderman ME, van Pampus EC, Tervaert JW.

Scand J Rheumatol. 2004;33(6):441-2. No abstract available.

PMID:
15794208
4.

Quantitative determination of the binding of beta2-glycoprotein I and prothrombin to phosphatidylserine-exposing blood platelets.

Bevers EM, Janssen MP, Comfurius P, Balasubramanian K, Schroit AJ, Zwaal RF, Willems GM.

Biochem J. 2005 Mar 1;386(Pt 2):271-9.

5.
6.

Thrombogenicity of polysaccharide-coated surfaces.

Keuren JF, Wielders SJ, Willems GM, Morra M, Cahalan L, Cahalan P, Lindhout T.

Biomaterials. 2003 May;24(11):1917-24.

PMID:
12615482
7.

Kinetics of prothrombin-mediated binding of lupus anticoagulant antibodies to phosphatidylserine-containing phospholipid membranes: an ellipsometric study.

Willems GM, Janssen MP, Comfurius P, Galli M, Zwaal RF, Bevers EM.

Biochemistry. 2002 Dec 3;41(48):14357-63.

PMID:
12450402
8.

Fibrinogen adsorption, platelet adhesion and thrombin generation at heparinized surfaces exposed to flowing blood.

Keuren JF, Wielders SJ, Willems GM, Morra M, Lindhout T.

Thromb Haemost. 2002 Apr;87(4):742-7.

PMID:
12008960
9.
10.

Purified protein S contains multimeric forms with increased APC-independent anticoagulant activity.

Seré KM, Janssen MP, Willems GM, Tans G, Rosing J, Hackeng TM.

Biochemistry. 2001 Jul 31;40(30):8852-60.

PMID:
11467946
11.

Binding of annexin V to membrane products of lipid peroxidation.

Balasubramanian K, Bevers EM, Willems GM, Schroit AJ.

Biochemistry. 2001 Jul 31;40(30):8672-6.

PMID:
11467926
12.

Complexes of anti-prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces.

Simmelink MJ, Horbach DA, Derksen RH, Meijers JC, Bevers EM, Willems GM, De Groot PG.

Br J Haematol. 2001 Jun;113(3):621-9.

PMID:
11380447
13.

Regulation of platelet factor Va-dependent thrombin generation by activated protein C at the surface of collagen-adherent platelets.

Briedé JJ, Tans G, Willems GM, Hemker HC, Lindhout T.

J Biol Chem. 2001 Mar 9;276(10):7164-8. Epub 2000 Dec 11.

14.

Antibodies to beta2-glycoprotein I associated with antiphospholipid syndrome suppress the inhibitory activity of tissue factor pathway inhibitor.

Salemink I, Blezer R, Willems GM, Galli M, Bevers E, Lindhout T.

Thromb Haemost. 2000 Oct;84(4):653-6.

PMID:
11057865
15.

No evidence for enhanced thrombin formation through displacement of annexin V by antiphospholipid antibodies.

Bevers EM, Janssen MP, Willems GM, Zwaal RF.

Thromb Haemost. 2000 May;83(5):792-4. No abstract available.

PMID:
10823284
16.

Competition of annexin V and anticardiolipin antibodies for binding to phosphatidylserine containing membranes.

Willems GM, Janssen MP, Comfurius P, Galli M, Zwaal RF, Bevers EM.

Biochemistry. 2000 Feb 29;39(8):1982-9.

PMID:
10684648
18.

Factor Xa cleavage of tissue factor pathway inhibitor is associated with loss of anticoagulant activity.

Salemink I, Franssen J, Willems GM, Hemker HC, Li A, Wun TC, Lindhout T.

Thromb Haemost. 1998 Aug;80(2):273-80.

PMID:
9716152
19.

Adsorption of proteins onto poly(ether urethane) with a phosphorylcholine moiety and influence of preadsorbed phospholipid.

van der Heiden AP, Willems GM, Lindhout T, Pijpers AP, Koole LH.

J Biomed Mater Res. 1998 May;40(2):195-203.

PMID:
9549614
20.

Transient high affinity binding of tissue factor pathway inhibitor-factor Xa complexes to negatively charged phospholipid membranes.

Willems GM, Janssen MP, Salemink I, Wun TC, Lindhout T.

Biochemistry. 1998 Mar 10;37(10):3321-8.

PMID:
9521652
21.

Initiation and propagation of blood coagulation at artificial surfaces studied in a capillary flow reactor.

Blezer R, Willems GM, Cahalan PT, Lindhout T.

Thromb Haemost. 1998 Feb;79(2):296-301.

PMID:
9493579
22.

Activation of blood coagulation at heparin-coated surfaces.

Blezer R, Fouache B, Willems GM, Lindhout T.

J Biomed Mater Res. 1997 Oct;37(1):108-13.

PMID:
9335355
23.

Prothrombinase is protected from inactivation by tissue factor pathway inhibitor: competition between prothrombin and inhibitor.

Franssen J, Salemink I, Willems GM, Wun TC, Hemker HC, Lindhout T.

Biochem J. 1997 Apr 1;323 ( Pt 1):33-7.

24.

Role of divalency in the high-affinity binding of anticardiolipin antibody-beta 2-glycoprotein I complexes to lipid membranes.

Willems GM, Janssen MP, Pelsers MM, Comfurius P, Galli M, Zwaal RF, Bevers EM.

Biochemistry. 1996 Oct 29;35(43):13833-42.

PMID:
8901526
25.

Tissue factor pathway inhibitor: regulation of its inhibitory activity by phospholipid surfaces.

Lindhout T, Salemink I, Valentin S, Willems GM.

Haemostasis. 1996 Oct;26 Suppl 4:89-97. Review.

PMID:
8979115
26.

Kinetics of factor VIII-von Willebrand factor association.

Vlot AJ, Koppelman SJ, Meijers JC, Dama C, van den Berg HM, Bouma BN, Sixma JJ, Willems GM.

Blood. 1996 Mar 1;87(5):1809-16.

27.
28.

Inhibition of prothrombinase at macroscopic lipid membranes: competition between antithrombin and prothrombin.

Billy D, Speijer H, Lindhout T, Hemker HC, Willems GM.

Biochemistry. 1995 Oct 17;34(41):13699-704.

PMID:
7577961
29.

Antithrombin activity of surface-bound heparin studied under flow conditions.

Lindhout T, Blezer R, Schoen P, Willems GM, Fouache B, Verhoeven M, Hendriks M, Cahalan L, Cahalan PT.

J Biomed Mater Res. 1995 Oct;29(10):1255-66.

PMID:
8557728
30.

Binding of blood coagulation factor VIII and its light chain to phosphatidylserine/phosphatidylcholine bilayers as measured by ellipsometry.

Spaargaren J, Giesen PL, Janssen MP, Voorberg J, Willems GM, van Mourik JA.

Biochem J. 1995 Sep 1;310 ( Pt 2):539-45.

31.

Assembly of the prothrombinase complex on lipid vesicles depends on the stereochemical configuration of the polar headgroup of phosphatidylserine.

Comfurius P, Smeets EF, Willems GM, Bevers EM, Zwaal RF.

Biochemistry. 1994 Aug 30;33(34):10319-24.

PMID:
8068668
32.

Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy.

Van de Werf F, Janssens L, Brzostek T, Mortelmans L, Wackers FJ, Willems GM, Heidbüchel H, Lesaffre E, Scheys I, Collen D, et al.

J Am Coll Cardiol. 1993 Aug;22(2):407-16.

33.

Adsorption and conversion of prothrombin on a rotating disc.

Willems GM, Giesen PL, Hermens WT.

Blood. 1993 Jul 15;82(2):497-504.

34.

Aggregation of phospholipid vesicles by a chimeric protein with the N-terminus of annexin I and the core of annexin V.

Andree HA, Willems GM, Hauptmann R, Maurer-Fogy I, Stuart MC, Hermens WT, Frederik PM, Reutelingsperger CP.

Biochemistry. 1993 May 4;32(17):4634-40.

PMID:
8485141
35.

Monitoring of unbound protein in vesicle suspensions with off-null ellipsometry.

Giesen PL, Willems GM, Hemker HC, Stuart MC, Hermens WT.

Biochim Biophys Acta. 1993 Apr 8;1147(1):125-31.

PMID:
8466922
36.

Circulatory models in assessment of cardiac enzyme release in dogs.

van Kreel BK, van der Veen FH, Willems GM, Hermens WT.

Am J Physiol. 1993 Mar;264(3 Pt 2):H747-54.

PMID:
8456977
37.

Effect of thrombolytic treatment delay on myocardial infarct size.

Hermens WT, Willems GM, Nijssen KM, Simoons ML.

Lancet. 1992 Nov 21;340(8830):1297. No abstract available.

PMID:
1359360
38.

Clustering of lipid-bound annexin V may explain its anticoagulant effect.

Andree HA, Stuart MC, Hermens WT, Reutelingsperger CP, Hemker HC, Frederik PM, Willems GM.

J Biol Chem. 1992 Sep 5;267(25):17907-12.

39.

Membrane-mediated assembly of the prothrombinase complex.

Giesen PL, Willems GM, Hemker HC, Hermens WT.

J Biol Chem. 1991 Oct 5;266(28):18720-5.

40.
41.

Surface exclusion and molecular mobility may explain Vroman effects in protein adsorption.

Willems GM, Hermens WT, Hemker HC.

J Biomater Sci Polym Ed. 1991;2(3):217-26.

PMID:
1854686
42.
43.

Simulation model for thrombin generation in plasma.

Willems GM, Lindhout T, Hermens WT, Hemker HC.

Haemostasis. 1991;21(4):197-207.

PMID:
1794746
44.

Time course of cellular enzyme release in dog heart injury.

van der Veen FH, Hermens WT, Willems GM, Schrijvers-van Schendel A, Mullers-Boumans ML, Reneman RS.

Circ Res. 1990 Nov;67(5):1257-66.

PMID:
2225357
46.

Enzymatic infarct size and its significance for evaluation of thrombolytic therapy after acute myocardial infarction.

Hermens WT, van der Veen FH, Willems GM, Reneman RS.

Circulation. 1990 May;81(5):1719-20. No abstract available.

PMID:
2331776
47.

Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

Andree HA, Reutelingsperger CP, Hauptmann R, Hemker HC, Hermens WT, Willems GM.

J Biol Chem. 1990 Mar 25;265(9):4923-8.

48.

Complete recovery in plasma of enzymes lost from the heart after permanent coronary artery occlusion in the dog.

Hermens WT, van der Veen FH, Willems GM, Mullers-Boumans ML, Schrijvers-van Schendel A, Reneman RS.

Circulation. 1990 Feb;81(2):649-59.

PMID:
2297868
49.

Estimation of the fractional catabolic rate constants for the elimination of cytosolic liver enzymes from plasma.

Peltenburg HG, Hermens WT, Willems GM, Flendrig JG, Schmidt E.

Hepatology. 1989 Nov;10(5):833-9.

PMID:
2807163
50.

Plasma activity of muscle enzymes: quantification of skeletal muscle damage and relationship with metabolic variables.

Janssen GM, Kuipers H, Willems GM, Does RJ, Janssen MP, Geurten P.

Int J Sports Med. 1989 Oct;10 Suppl 3:S160-8.

PMID:
2599735

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