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Items: 1 to 50 of 115

1.

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts.

Patel JJ, Bourne LE, Davies BK, Arnett TR, MacRae VE, Wheeler-Jones CP, Orriss IR.

Exp Cell Res. 2019 Jul 1;380(1):100-113. doi: 10.1016/j.yexcr.2019.04.020. Epub 2019 Apr 18.

2.

The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-β1.

Lawson JS, Liu HH, Syme HM, Purcell R, Wheeler-Jones CPD, Elliott J.

PLoS One. 2018 Aug 23;13(8):e0202577. doi: 10.1371/journal.pone.0202577. eCollection 2018.

3.

Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling.

Al-Rashed F, Calay D, Lang M, Thornton CC, Bauer A, Kiprianos A, Haskard DO, Seneviratne A, Boyle JJ, Schönthal AH, Wheeler-Jones CP, Mason JC.

Sci Rep. 2018 Apr 19;8(1):6271. doi: 10.1038/s41598-018-24548-z.

4.

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor β1.

Lawson JS, Syme HM, Wheeler-Jones CPD, Elliott J.

BMC Vet Res. 2018 Mar 9;14(1):76. doi: 10.1186/s12917-018-1387-2.

5.

Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms.

Patel JJ, Zhu D, Opdebeeck B, D'Haese P, Millán JL, Bourne LE, Wheeler-Jones CPD, Arnett TR, MacRae VE, Orriss IR.

J Cell Physiol. 2018 Apr;233(4):3230-3243. doi: 10.1002/jcp.26166. Epub 2017 Oct 4.

6.

Direct Activation of NADPH Oxidase 2 by 2-Deoxyribose-1-Phosphate Triggers Nuclear Factor Kappa B-Dependent Angiogenesis.

Vara D, Watt JM, Fortunato TM, Mellor H, Burgess M, Wicks K, Mace K, Reeksting S, Lubben A, Wheeler-Jones CPD, Pula G.

Antioxid Redox Signal. 2018 Jan 10;28(2):110-130. doi: 10.1089/ars.2016.6869. Epub 2017 Sep 18.

7.

Natriuretic peptide activation of extracellular regulated kinase 1/2 (ERK1/2) pathway by particulate guanylyl cyclases in GH3 somatolactotropes.

Jonas KC, Melrose T, Thompson IR, Baxter GF, Lipscomb VJ, Niessen SJ, Lawson C, McArdle CA, Roberson MS, McGonnell IM, Wheeler-Jones CP, Fowkes RC.

Cell Tissue Res. 2017 Sep;369(3):567-578. doi: 10.1007/s00441-017-2624-x. Epub 2017 Apr 27.

8.

Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function.

Clarkin CE, Mahmoud M, Liu B, Sobamowo EO, King A, Arthur H, Jones PM, Wheeler-Jones CP.

BMC Res Notes. 2016 Jul 25;9:362. doi: 10.1186/s13104-016-2142-z.

9.

Urinary active transforming growth factor β in feline chronic kidney disease.

Lawson JS, Syme HM, Wheeler-Jones CP, Elliott J.

Vet J. 2016 Aug;214:1-6. doi: 10.1016/j.tvjl.2016.02.004. Epub 2016 Feb 12.

10.

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway.

Latham Birt SH, Purcell R, Botham KM, Wheeler-Jones CP.

J Lipid Res. 2016 Jul;57(7):1204-18. doi: 10.1194/jlr.M067108. Epub 2016 May 16.

11.

Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts.

Tivers MS, Lipscomb VJ, Smith KC, Wheeler-Jones CP, House AK.

Vet J. 2015 Dec;206(3):404-13. doi: 10.1016/j.tvjl.2015.07.006. Epub 2015 Jul 7.

PMID:
26383860
12.

A thin layer angiogenesis assay: a modified basement matrix assay for assessment of endothelial cell differentiation.

Faulkner A, Purcell R, Hibbert A, Latham S, Thomson S, Hall WL, Wheeler-Jones C, Bishop-Bailey D.

BMC Cell Biol. 2014 Dec 5;15:41. doi: 10.1186/s12860-014-0041-5.

13.

Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury.

Lawson J, Elliott J, Wheeler-Jones C, Syme H, Jepson R.

Vet J. 2015 Jan;203(1):18-26. doi: 10.1016/j.tvjl.2014.10.009. Epub 2014 Oct 24. Review.

14.

Expression of protease-activated receptor 1 and 2 and anti-tubulogenic activity of protease-activated receptor 1 in human endothelial colony-forming cells.

Fortunato TM, Vara DS, Wheeler-Jones CP, Pula G.

PLoS One. 2014 Oct 7;9(10):e109375. doi: 10.1371/journal.pone.0109375. eCollection 2014.

15.

Markers of angiogenesis associated with surgical attenuation of congenital portosystemic shunts in dogs.

Tivers MS, House AK, Smith KC, Wheeler-Jones CP, Lipscomb VJ.

J Vet Intern Med. 2014 Sep-Oct;28(5):1424-32. doi: 10.1111/jvim.12411. Epub 2014 Aug 8.

16.
17.

Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated skeletal muscle insulin resistance.

Talbot NA, Wheeler-Jones CP, Cleasby ME.

Mol Cell Endocrinol. 2014 Aug 5;393(1-2):129-42. doi: 10.1016/j.mce.2014.06.010. Epub 2014 Jun 26.

18.

Lipid-metabolizing CYPs in the regulation and dysregulation of metabolism.

Bishop-Bailey D, Thomson S, Askari A, Faulkner A, Wheeler-Jones C.

Annu Rev Nutr. 2014;34:261-79. doi: 10.1146/annurev-nutr-071813-105747. Epub 2014 Apr 24. Review.

PMID:
24819323
19.

Markers of hepatic regeneration associated with surgical attenuation of congenital portosystemic shunts in dogs.

Tivers MS, Lipscomb VJ, Smith KC, Wheeler-Jones CP, House AK.

Vet J. 2014 May;200(2):305-11. doi: 10.1016/j.tvjl.2014.02.027. Epub 2014 Feb 28.

PMID:
24662025
20.

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes.

Thompson IR, Mirczuk SM, Smith L, Lessey AJ, Simbi B, Sunters A, Baxter GF, Lipscomb VJ, McGonnell IM, Wheeler-Jones CP, Mukherjee A, Roberson MS, McArdle CA, Fowkes RC.

Cell Tissue Res. 2014 Feb;355(2):425-36. doi: 10.1007/s00441-013-1763-y. Epub 2013 Dec 20.

21.

Postprandial lipoproteins and the molecular regulation of vascular homeostasis.

Botham KM, Wheeler-Jones CP.

Prog Lipid Res. 2013 Oct;52(4):446-64. doi: 10.1016/j.plipres.2013.06.001. Epub 2013 Jun 15. Review.

PMID:
23774609
22.

Activin receptor-like kinase 5 inhibition reverses impairment of endothelial cell viability by endogenous islet mesenchymal stromal cells.

Clarkin CE, King AJ, Dhadda P, Chagastelles P, Nardi N, Wheeler-Jones CP, Jones PM.

Stem Cells. 2013 Mar;31(3):547-59. doi: 10.1002/stem.1305.

23.

Endoglin (CD105) is not a specific selection marker for endothelial cells in human islets of Langerhans.

Wheeler-Jones CP, Clarkin CE, Farrar CE, Dhadda P, Chagastelles P, Nardi N, Jones PM.

Diabetologia. 2013 Jan;56(1):222-4. doi: 10.1007/s00125-012-2763-2. Epub 2012 Oct 28. No abstract available.

PMID:
23104640
24.

Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a role for C-type natriuretic peptide.

Thompson IR, Chand AN, King PJ, Ansorge O, Karavitaki N, Jones CA, Rahmutula D, Gardner DG, Zivkovic V, Wheeler-Jones CP, McGonnell IM, Korbonits M, Anderson RA, Wass JA, McNeilly AS, Fowkes RC.

Endocr Relat Cancer. 2012 Jul 22;19(4):497-508. doi: 10.1530/ERC-12-0129. Print 2012 Aug.

PMID:
22645228
25.

Vascular endothelial growth factor (VEGF) and VEGF receptor expression in biopsy samples of liver from dogs with congenital portosystemic shunts.

Tivers MS, Lipscomb VJ, Scase TJ, Priestnall SL, House AK, Gates H, Wheeler-Jones CP, Smith KC.

J Comp Pathol. 2012 Jul;147(1):55-61. doi: 10.1016/j.jcpa.2011.09.001. Epub 2011 Oct 11.

PMID:
21996035
26.

Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid.

Graham VS, Lawson C, Wheeler-Jones CP, Perona JS, Ruiz-Gutierrez V, Botham KM.

Eur J Nutr. 2012 Apr;51(3):301-9. doi: 10.1007/s00394-011-0215-2. Epub 2011 Jun 17.

PMID:
21681438
27.

Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells.

Garonna E, Botham KM, Birdsey GM, Randi AM, Gonzalez-Perez RR, Wheeler-Jones CP.

PLoS One. 2011 Apr 18;6(4):e18823. doi: 10.1371/journal.pone.0018823.

28.

Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase.

Clarkin CE, Allen S, Wheeler-Jones CP, Bastow ER, Pitsillides AA.

Matrix Biol. 2011 Apr;30(3):163-8. doi: 10.1016/j.matbio.2011.01.002. Epub 2011 Feb 1.

29.

Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor.

Graham VS, Di Maggio P, Armengol S, Lawson C, Wheeler-Jones CP, Botham KM.

Biochim Biophys Acta. 2011 Mar;1811(3):209-20. doi: 10.1016/j.bbalip.2010.11.008. Epub 2010 Dec 8.

PMID:
21145417
30.

Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate.

Pula G, Garonna E, Dunn WB, Hirano M, Pizzorno G, Campanella M, Schwartz EL, El Kouni MH, Wheeler-Jones CP.

Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2631-8. doi: 10.1161/ATVBAHA.110.215855. Epub 2010 Sep 30.

PMID:
20884872
31.

Targeting hyaluronan of the endothelial glycocalyx for therapeutic intervention.

Wheeler-Jones CP, Farrar CE, Pitsillides AA.

Curr Opin Investig Drugs. 2010 Sep;11(9):997-1006. Review.

PMID:
20730694
32.

Regulation of UDP-glucose dehydrogenase is sufficient to modulate hyaluronan production and release, control sulfated GAG synthesis, and promote chondrogenesis.

Clarkin CE, Allen S, Kuiper NJ, Wheeler BT, Wheeler-Jones CP, Pitsillides AA.

J Cell Physiol. 2011 Mar;226(3):749-61. doi: 10.1002/jcp.22393.

PMID:
20717929
33.

Influence of chylomicron remnants on human monocyte activation in vitro.

Bentley C, Hathaway N, Widdows J, Bejta F, De Pascale C, Avella M, Wheeler-Jones CP, Botham KM, Lawson C.

Nutr Metab Cardiovasc Dis. 2011 Nov;21(11):871-8. doi: 10.1016/j.numecd.2010.02.019. Epub 2010 Jul 31.

34.

Endothelial cells as targets for chylomicron remnants.

Dalla-Riva J, Garonna E, Elliott J, Botham KM, Wheeler-Jones CP.

Atheroscler Suppl. 2010 Jun;11(1):31-7. doi: 10.1016/j.atherosclerosissup.2010.04.001. Epub 2010 May 1. Review.

PMID:
20439166
35.

Conventional myosins - unconventional functions.

Chantler PD, Wylie SR, Wheeler-Jones CP, McGonnell IM.

Biophys Rev. 2010 May;2(2):67-82. doi: 10.1007/s12551-010-0030-7. Epub 2010 Mar 9. Review.

36.

C-type natriuretic peptide regulation of guanosine-3',5'-cyclic monophosphate production in human endothelial cells.

Rautureau Y, Gowers I, Wheeler-Jones CP, Baxter GF.

Auton Autacoid Pharmacol. 2010 Jul;30(3):185-92. doi: 10.1111/j.1474-8673.2009.00449.x. Epub 2010 Jan 19.

PMID:
20085572
37.

Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium.

Hamdulay SS, Wang B, Birdsey GM, Ali F, Dumont O, Evans PC, Haskard DO, Wheeler-Jones CP, Mason JC.

Free Radic Biol Med. 2010 Apr 15;48(8):1013-23. doi: 10.1016/j.freeradbiomed.2010.01.017. Epub 2010 Jan 18.

PMID:
20083195
38.

The expression of angiogenic growth factors and their receptors in ovarian follicles throughout the estrous cycle in the ewe.

Chowdhury MW, Scaramuzzi RJ, Wheeler-Jones CP, Khalid M.

Theriogenology. 2010 Apr 15;73(7):856-72. doi: 10.1016/j.theriogenology.2009.10.011. Epub 2009 Dec 29.

PMID:
20042232
39.

The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe.

Kershaw-Young CM, Scaramuzzi RJ, McGowan MR, Pitsillides AA, Wheeler-Jones CP, Khalid M.

Theriogenology. 2010 Mar 15;73(5):620-8. doi: 10.1016/j.theriogenology.2009.10.018. Epub 2009 Dec 23.

PMID:
20031195
40.

Protease-activated receptors, cyclo-oxygenases and pro-angiogenic signalling in endothelial cells.

Wheeler-Jones CP, Farrar C, Garonna E.

Biochem Soc Trans. 2009 Dec;37(Pt 6):1179-83. doi: 10.1042/BST0371179.

PMID:
19909242
41.

Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles.

De Pascale C, Graham V, Fowkes RC, Wheeler-Jones CP, Botham KM.

FEBS J. 2009 Oct;276(19):5689-702. doi: 10.1111/j.1742-4658.2009.07260.x. Epub 2009 Sep 2.

42.

Expression of blood coagulation factors on monocytes after exposure to TNF-treated endothelium in a novel whole blood model of arterial flow.

Macey MG, Wolf SI, Wheeler-Jones CP, Lawson C.

J Immunol Methods. 2009 Oct 31;350(1-2):133-41. doi: 10.1016/j.jim.2009.08.007. Epub 2009 Aug 21.

PMID:
19699743
43.

Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alphaT3-1 and LbetaT2 gonadotroph cells.

Thompson IR, Chand AN, Jonas KC, Burrin JM, Steinhelper ME, Wheeler-Jones CP, McArdle CA, Fowkes RC.

J Endocrinol. 2009 Nov;203(2):215-29. doi: 10.1677/JOE-09-0189. Epub 2009 Aug 7.

PMID:
19666697
44.

Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases.

Brooks AC, Menzies-Gow NJ, Wheeler-Jones CP, Bailey SR, Elliott J, Cunningham FM.

J Vet Pharmacol Ther. 2009 Apr;32(2):189-96. doi: 10.1111/j.1365-2885.2008.01020.x.

PMID:
19290950
45.

Endotoxin-induced activation of equine digital vein endothelial cells: role of p38 MAPK.

Brooks AC, Menzies-Gow NJ, Wheeler-Jones C, Bailey SR, Cunningham FM, Elliott J.

Vet Immunol Immunopathol. 2009 Jun 15;129(3-4):174-80. doi: 10.1016/j.vetimm.2008.11.008. Epub 2008 Nov 7.

PMID:
19108900
46.

Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication?

Clarkin CE, Garonna E, Pitsillides AA, Wheeler-Jones CP.

Exp Cell Res. 2008 Oct 15;314(17):3152-61. doi: 10.1016/j.yexcr.2008.07.027. Epub 2008 Aug 7.

PMID:
18718465
47.

Ammonia impairs neutrophil phagocytic function in liver disease.

Shawcross DL, Wright GA, Stadlbauer V, Hodges SJ, Davies NA, Wheeler-Jones C, Pitsillides AA, Jalan R.

Hepatology. 2008 Oct;48(4):1202-12. doi: 10.1002/hep.22474.

PMID:
18697192
48.
49.

Effects of lycopene on the induction of foam cell formation by modified LDL.

Napolitano M, De Pascale C, Wheeler-Jones C, Botham KM, Bravo E.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1820-7. Epub 2007 Oct 2.

50.

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