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Items: 1 to 50 of 53

1.

CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program.

Thaventhiran T, Wong W, Alghanem AF, Alhumeed N, Aljasir MA, Ramsey S, Sethu S, Yeang HXA, Chadwick AE, Cross M, Webb SD, Djouhri L, Ball C, Stebbings R, Sathish JG.

Monoclon Antib Immunodiagn Immunother. 2019 Apr;38(2):60-69. doi: 10.1089/mab.2018.0042.

2.

In vitro Liver Zonation of Primary Rat Hepatocytes.

Tomlinson L, Hyndman L, Firman JW, Bentley R, Kyffin JA, Webb SD, McGinty S, Sharma P.

Front Bioeng Biotechnol. 2019 Feb 18;7:17. doi: 10.3389/fbioe.2019.00017. eCollection 2019.

3.

Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway.

Tomlinson L, Lu ZQ, Bentley RA, Colley HE, Murdoch C, Webb SD, Cross MJ, Copple IM, Sharma P.

Biomed Pharmacother. 2019 Apr;112:108637. doi: 10.1016/j.biopha.2019.108637. Epub 2019 Feb 22.

4.

Characterisation of a functional rat hepatocyte spheroid model.

Kyffin JA, Sharma P, Leedale J, Colley HE, Murdoch C, Harding AL, Mistry P, Webb SD.

Toxicol In Vitro. 2019 Mar;55:160-172. doi: 10.1016/j.tiv.2018.12.014. Epub 2018 Dec 20.

5.

Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture.

Kelly RA, Leedale J, Harrell A, Beard DA, Randle LE, Chadwick AE, Webb SD.

PLoS One. 2018 Nov 29;13(11):e0207803. doi: 10.1371/journal.pone.0207803. eCollection 2018.

6.

A critical review of adverse effects to the kidney: mechanisms, data sources, and in silico tools to assist prediction.

Pletz J, Enoch SJ, Jais DM, Mellor CL, Pawar G, Firman JW, Madden JC, Webb SD, Tagliati CA, Cronin MTD.

Expert Opin Drug Metab Toxicol. 2018 Dec;14(12):1225-1253. doi: 10.1080/17425255.2018.1539076. Epub 2018 Nov 25. Review.

PMID:
30345815
7.

A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity.

Leedale J, Sharkey KJ, Colley HE, Norton ÁM, Peeney D, Mason CL, Sathish JG, Murdoch C, Sharma P, Webb SD.

iScience. 2018 Jun 29;4:84-96. doi: 10.1016/j.isci.2018.05.012. Epub 2018 May 18.

8.

Systems Toxicology Approach to Identifying Paracetamol Overdose.

Mason CL, Leedale J, Tasoulis S, Jarman I, Antoine DJ, Webb SD.

CPT Pharmacometrics Syst Pharmacol. 2018 Jun;7(6):394-403. doi: 10.1002/psp4.12298. Epub 2018 Apr 18.

9.

Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment.

Kyffin JA, Sharma P, Leedale J, Colley HE, Murdoch C, Mistry P, Webb SD.

Toxicol In Vitro. 2018 Apr;48:262-275. doi: 10.1016/j.tiv.2018.01.023. Epub 2018 Feb 1. Review.

10.

Expression and enzyme activity of cytochrome P450 enzymes CYP3A4 and CYP3A5 in human skin and tissue-engineered skin equivalents.

Smith SA, Colley HE, Sharma P, Slowik KM, Sison-Young R, Sneddon A, Webb SD, Murdoch C.

Exp Dermatol. 2018 May;27(5):473-475. doi: 10.1111/exd.13483. Epub 2018 Jan 5.

11.

Characterization of a functional C3A liver spheroid model.

Gaskell H, Sharma P, Colley HE, Murdoch C, Williams DP, Webb SD.

Toxicol Res (Camb). 2016 Jun 1;5(4):1053-1065. Epub 2016 Apr 27.

12.

Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.

Thaventhiran T, Alhumeed N, Yeang HX, Sethu S, Downey JS, Alghanem AF, Olayanju A, Smith EL, Cross MJ, Webb SD, Williams DP, Bristow A, Ball C, Stebbings R, Sathish JG.

MAbs. 2014;6(5):1290-9. doi: 10.4161/mabs.29758. Epub 2014 Oct 30.

13.

Combined mathematical modelling and experimentation to predict polymersome uptake by oral cancer cells.

Sorrell I, Shipley RJ, Hearnden V, Colley HE, Thornhill MH, Murdoch C, Webb SD.

Nanomedicine. 2014 Feb;10(2):339-48. doi: 10.1016/j.nano.2013.08.013. Epub 2013 Sep 10.

14.

Theoretical predictions of lactate and hydrogen ion distributions in tumours.

Al-Husari M, Webb SD.

PLoS One. 2013 Aug 21;8(8):e72020. doi: 10.1371/journal.pone.0072020. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/d5a0e265-b707-476d-9975-3278f9defabf.

15.

A cellular automaton model examining the effects of oxygen, hydrogen ions and lactate on early tumour growth.

Al-Husari M, Murdoch C, Webb SD.

J Math Biol. 2014 Oct;69(4):839-73. doi: 10.1007/s00285-013-0719-x. Epub 2013 Aug 28.

PMID:
23982261
16.

Transport of gabapentin by LAT1 (SLC7A5).

Dickens D, Webb SD, Antonyuk S, Giannoudis A, Owen A, Rädisch S, Hasnain SS, Pirmohamed M.

Biochem Pharmacol. 2013 Jun 1;85(11):1672-83. doi: 10.1016/j.bcp.2013.03.022. Epub 2013 Apr 6.

PMID:
23567998
17.

Acid-mediated tumour cell invasion: a discrete modelling approach using the extended Potts model.

Al-Husari M, Webb SD.

Clin Exp Metastasis. 2013 Aug;30(6):793-806. doi: 10.1007/s10585-013-9579-4. Epub 2013 Mar 31.

PMID:
23543037
18.

The role of spatial population structure on the evolution of parasites with acquired immunity and demography.

Webb SD, Keeling MJ, Boots M.

J Theor Biol. 2013 May 7;324:21-31. doi: 10.1016/j.jtbi.2013.01.015. Epub 2013 Jan 31.

PMID:
23376644
19.

Regulation of tumour intracellular pH: a mathematical model examining the interplay between H+ and lactate.

Al-Husari M, Webb SD.

J Theor Biol. 2013 Apr 7;322:58-71. doi: 10.1016/j.jtbi.2013.01.007. Epub 2013 Jan 20.

PMID:
23340437
20.

A theoretical study of the role of spatial population structure in the evolution of parasite virulence.

Webb SD, Keeling MJ, Boots M.

Theor Popul Biol. 2013 Mar;84:36-45. doi: 10.1016/j.tpb.2012.11.008. Epub 2012 Dec 26.

PMID:
23274478
21.

Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour.

Neilson MP, Veltman DM, van Haastert PJ, Webb SD, Mackenzie JA, Insall RH.

PLoS Biol. 2011 May;9(5):e1000618. doi: 10.1371/journal.pbio.1000618. Epub 2011 May 17.

22.

Use of the parameterised finite element method to robustly and efficiently evolve the edge of a moving cell.

Neilson MP, Mackenzie JA, Webb SD, Insall RH.

Integr Biol (Camb). 2010 Nov;2(11-12):687-95. doi: 10.1039/c0ib00047g. Epub 2010 Oct 20.

PMID:
20959932
23.

Emerging modelling methodologies in medicine and biology, Introduction to the special issue.

Davies J, Grinfeld M, Webb SD.

Theory Biosci. 2011 Mar;130(1):1-3. doi: 10.1007/s12064-010-0104-x. No abstract available.

PMID:
20798999
24.

Structural instability in an autophosphorylating kinase switch.

Grinfeld M, Webb SD.

Math Biosci. 2009 Jun;219(2):92-6. doi: 10.1016/j.mbs.2009.02.005. Epub 2009 Mar 19.

25.

Host-parasite interactions between the local and the mean-field: how and when does spatial population structure matter?

Webb SD, Keeling MJ, Boots M.

J Theor Biol. 2007 Nov 7;249(1):140-52. Epub 2007 Jun 16.

PMID:
17719608
26.

Macrophage-based anti-cancer therapy: modelling different modes of tumour targeting.

Webb SD, Owen MR, Byrne HM, Murdoch C, Lewis CE.

Bull Math Biol. 2007 Jul;69(5):1747-76. Epub 2007 Mar 1.

PMID:
17333419
27.

Spatially extended host-parasite interactions: the role of recovery and immunity.

Webb SD, Keeling MJ, Boots M.

Theor Popul Biol. 2007 Mar;71(2):251-66. Epub 2006 Sep 22.

PMID:
17084872
28.

Modelling aspects of cancer dynamics: a review.

Byrne HM, Alarcon T, Owen MR, Webb SD, Maini PK.

Philos Trans A Math Phys Eng Sci. 2006 Jun 15;364(1843):1563-78.

PMID:
16766361
29.

Intra-membrane ligand diffusion and cell shape modulate juxtacrine patterning.

Webb SD, Owen MR.

J Theor Biol. 2004 Sep 7;230(1):99-117.

PMID:
15276004
30.

Oscillations and patterns in spatially discrete models for developmental intercellular signalling.

Webb SD, Owen MR.

J Math Biol. 2004 Apr;48(4):444-76. Epub 2003 Oct 27.

PMID:
15052506
31.

Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma.

Webb SD, Cleland JL, Carpenter JF, Randolph TW.

J Pharm Sci. 2003 Apr;92(4):715-29.

PMID:
12661058
32.

Cells behaving badly: a theoretical model for the Fas/FasL system in tumour immunology.

Webb SD, Sherratt JA, Fish RG.

Math Biosci. 2002 Sep-Oct;179(2):113-29.

PMID:
12208611
33.

Characterization and validation of the gamma-scintigraphic method for determining liquid holdup in foam.

Webb SD, Page RC, Jay M, Bummer PM.

Appl Radiat Isot. 2002 Aug;57(2):243-55.

PMID:
12150284
34.

Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations.

Webb SD, Golledge SL, Cleland JL, Carpenter JF, Randolph TW.

J Pharm Sci. 2002 Jun;91(6):1474-87.

PMID:
12115847
36.

Modelling tumour acidity and invasion.

Webb SD, Sherratt JA, Fish RG.

Novartis Found Symp. 2001;240:169-81; discussion 181-5. Review.

PMID:
11727928
37.

Electrochemical determination of dissolution rates of lyophilized pharmaceutical formulations.

Webb SD, Koval CA, Randolph CM, Randolph TW.

Anal Chem. 2001 Nov 1;73(21):5296-301.

PMID:
11721932
38.
39.

Alterations in proteolytic activity at low pH and its association with invasion: a theoretical model.

Webb SD, Sherratt JA, Fish RG.

Clin Exp Metastasis. 1999 Jul;17(5):397-407.

PMID:
10651306
40.

Mathematical modelling of tumour acidity: regulation of intracellular pH.

Webb SD, Sherratt JA, Fish RG.

J Theor Biol. 1999 Jan 21;196(2):237-50.

PMID:
9990741
41.

Spatial Response of Mammals to Late Quaternary Environmental Fluctuations

Graham RW, Lundelius EL Jr, Graham MA, Schroeder EK, Toomey RS III, Anderson E, Barnosky AD, Burns JA, Churcher CS, Grayson DK, Guthrie RD, Harington CR, Jefferson GT, Martin LD, McDonald HG, Morlan RE, Semken HA Jr, Webb SD, Werdelin L, Wilson MC.

Science. 1996 Jun 14;272(5268):1601-6.

PMID:
8662471
42.

Biological implications of the middle miocene Amazon seaway.

Webb SD.

Science. 1995 Jul 21;269(5222):361-2. No abstract available.

PMID:
17841255
43.

Life in west gondwana.

Webb SD.

Science. 1994 Apr 22;264(5158):601. No abstract available.

PMID:
17732742
44.

A repopulation.

Webb SD.

Science. 1991 May 17;252(5008):1006-8. No abstract available.

PMID:
17843256
46.

Tales of paleontology: kadimakara.

Webb SD.

Science. 1987 Mar 13;235(4794):1408b-9b. No abstract available.

PMID:
17829982
47.

A chronicle of paleontology: discoverers of the lost world.

Webb SD.

Science. 1984 Nov 16;226(4676):825-6. No abstract available.

PMID:
17759886
48.

THE REBIRTH OF BIOGEOGRAPHY.

Webb SD.

Evolution. 1984 Jan;38(1):229-230. doi: 10.1111/j.1558-5646.1984.tb00278.x. No abstract available.

PMID:
28556087
49.

Mammalian evolution and the great american interchange.

Marshall LG, Webb SD, Sepkoski JJ Jr, Raup DM.

Science. 1982 Mar 12;215(4538):1351-7.

PMID:
17753000
50.

Rural-urban differences in the use of stress-alleviative drugs.

Webb SD, Collette J.

AJS. 1977 Nov;83(3):700-7. No abstract available.

PMID:
931045

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