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Fatal Mitragynine-Associated Toxicity in Canada: A Case Report and Review of the Literature.

Wang C, Walker AE.

Acad Forensic Pathol. 2018 Jun;8(2):340-346. doi: 10.1177/1925362118782076. Epub 2018 Jun 6.


The Adult Pancreas in Trauma and Disease.

Walker AE.

Acad Forensic Pathol. 2018 Jun;8(2):192-218. doi: 10.1177/1925362118781612. Epub 2018 Jun 6. Review.


Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells.

Bill M, Papaioannou D, Karunasiri M, Kohlschmidt J, Pepe F, Walker CJ, Walker AE, Brannan Z, Pathmanathan A, Zhang X, Mrózek K, LaRocco A, Volinia S, Bloomfield CD, Garzon R, Dorrance AM.

Leukemia. 2019 Mar 11. doi: 10.1038/s41375-019-0429-5. [Epub ahead of print]


Deletion of Robo4 prevents high-fat diet-induced adipose artery and systemic metabolic dysfunction.

Phuong TTT, Walker AE, Henson GD, Machin DR, Li DY, Donato AJ, Lesniewski LA.

Microcirculation. 2019 Jul;26(5):e12540. doi: 10.1111/micc.12540. Epub 2019 Apr 5.


The pro-atherogenic response to disturbed blood flow is increased by a western diet, but not by old age.

Walker AE, Breevoort SR, Durrant JR, Liu Y, Machin DR, Dobson PS, Nielson EI, Meza AJ, Islam MT, Donato AJ, Lesniewski LA.

Sci Rep. 2019 Feb 27;9(1):2925. doi: 10.1038/s41598-019-39466-x.


Cerebral and skeletal muscle feed artery vasoconstrictor responses in a mouse model with greater large elastic artery stiffness.

Walker AE, Kronquist EK, Chinen KT, Reihl KD, Li DY, Lesniewski LA, Donato AJ.

Exp Physiol. 2019 Mar;104(3):434-442. doi: 10.1113/EP087453. Epub 2019 Feb 3.


Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress.

Morgan RG, Walker AE, Trott DW, Machin DR, Henson GD, Reihl KD, Cawthon RM, Denchi EL, Liu Y, Bloom SI, Phuong TT, Richardson RS, Lesniewski LA, Donato AJ.

J Mol Cell Cardiol. 2019 Feb;127:74-82. doi: 10.1016/j.yjmcc.2018.11.014. Epub 2018 Nov 29.


Telomere uncapping and vascular aging.

Morgan RG, Donato AJ, Walker AE.

Am J Physiol Heart Circ Physiol. 2018 Jul 1;315(1):H1-H5. doi: 10.1152/ajpheart.00008.2018. Epub 2018 Mar 16. Review.


A Bayesian Network Meta-Analysis to Synthesize the Influence of Contexts of Scaffolding Use on Cognitive Outcomes in STEM Education.

Belland BR, Walker AE, Kim NJ.

Rev Educ Res. 2017 Dec;87(6):1042-1081. doi: 10.3102/0034654317723009. Epub 2017 Aug 21.


Ants are the major agents of resource removal from tropical rainforests.

Griffiths HM, Ashton LA, Walker AE, Hasan F, Evans TA, Eggleton P, Parr CL.

J Anim Ecol. 2018 Jan;87(1):293-300. doi: 10.1111/1365-2656.12728. Epub 2017 Aug 8.


Synthesizing Results From Empirical Research on Computer-Based Scaffolding in STEM Education: A Meta-Analysis.

Belland BR, Walker AE, Kim NJ, Lefler M.

Rev Educ Res. 2017 Apr;87(2):309-344. doi: 10.3102/0034654316670999. Epub 2016 Oct 10.


SEM-microphotogrammetry, a new take on an old method for generating high-resolution 3D models from SEM images.

Ball AD, Job PA, Walker AEL.

J Microsc. 2017 Aug;267(2):214-226. doi: 10.1111/jmi.12560. Epub 2017 Mar 22.


Addressing Cognitive Deficits in Schizophrenia: Toward a Neurobiologically Informed Approach.

Walker AE, Spring JD, Travis MJ.

Biol Psychiatry. 2017 Jan 1;81(1):e1-e3. doi: 10.1016/j.biopsych.2016.10.023. No abstract available.


Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways.

Lesniewski LA, Seals DR, Walker AE, Henson GD, Blimline MW, Trott DW, Bosshardt GC, LaRocca TJ, Lawson BR, Zigler MC, Donato AJ.

Aging Cell. 2017 Feb;16(1):17-26. doi: 10.1111/acel.12524. Epub 2016 Sep 22.


Age-related arterial telomere uncapping and senescence is greater in women compared with men.

Walker AE, Morgan RG, Ives SJ, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ.

Exp Gerontol. 2016 Jan;73:65-71. doi: 10.1016/j.exger.2015.11.009. Epub 2015 Nov 19.


Improved detection of rough defects for ultrasonic nondestructive evaluation inspections based on finite element modeling of elastic wave scattering.

Pettit JR, Walker AE, Lowe MJ.

IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Oct;62(10):1797-808. doi: 10.1109/TUFFC.2015.007140.


Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium.

Gibson CC, Davis CT, Zhu W, Bowman-Kirigin JA, Walker AE, Tai Z, Thomas KR, Donato AJ, Lesniewski LA, Li DY.

PLoS One. 2015 Oct 15;10(10):e0140370. doi: 10.1371/journal.pone.0140370. eCollection 2015.


Reduced large elastic artery stiffness with regular aerobic exercise in middle-aged and older adults: potential role of suppressed nuclear factor κ B signalling.

Jablonski KL, Donato AJ, Fleenor BS, Nowlan MJ, Walker AE, Kaplon RE, Ballak DB, Seals DR.

J Hypertens. 2015 Dec;33(12):2477-82. doi: 10.1097/HJH.0000000000000742.


Fatal foreign-body granulomatous pulmonary embolization due to microcrystalline cellulose in a patient receiving total parenteral nutrition: all crystals are not what they seem.

Strickland S, Pena E, Walker AE.

Forensic Sci Med Pathol. 2015 Jun;11(2):255-61. doi: 10.1007/s12024-015-9664-x. Epub 2015 Mar 4.


Cellular and molecular biology of aging endothelial cells.

Donato AJ, Morgan RG, Walker AE, Lesniewski LA.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):122-35. doi: 10.1016/j.yjmcc.2015.01.021. Epub 2015 Feb 2. Review.


Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness.

Walker AE, Henson GD, Reihl KD, Morgan RG, Dobson PS, Nielson EI, Ling J, Mecham RP, Li DY, Lesniewski LA, Donato AJ.

J Physiol. 2015 Apr 15;593(8):1931-43. doi: 10.1113/jphysiol.2014.285338. Epub 2015 Feb 20.


Systemic sclerosis induces pronounced peripheral vascular dysfunction characterized by blunted peripheral vasoreactivity and endothelial dysfunction.

Frech T, Walker AE, Barrett-O'Keefe Z, Hopkins PN, Richardson RS, Wray DW, Donato AJ.

Clin Rheumatol. 2015 May;34(5):905-13. doi: 10.1007/s10067-014-2834-5. Epub 2014 Dec 16.


Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.

Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY.

Circulation. 2015 Jan 20;131(3):289-99. doi: 10.1161/CIRCULATIONAHA.114.010403. Epub 2014 Dec 8.


The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction.

Donato AJ, Henson GD, Hart CR, Layec G, Trinity JD, Bramwell RC, Enz RA, Morgan RG, Reihl KD, Hazra S, Walker AE, Richardson RS, Lesniewski LA.

J Physiol. 2014 Sep 15;592(18):4083-96. doi: 10.1113/jphysiol.2014.274175. Epub 2014 Jul 18.


Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor κB.

Walker AE, Kaplon RE, Pierce GL, Nowlan MJ, Seals DR.

Clin Sci (Lond). 2014 Dec;127(11):645-54. doi: 10.1042/CS20140030.


Dichotomous mechanisms of aortic stiffening in high-fat diet fed young and old B6D2F1 mice.

Henson GD, Walker AE, Reihl KD, Donato AJ, Lesniewski LA.

Physiol Rep. 2014 Mar 27;2(3):e00268. doi: 10.1002/phy2.268. Print 2014.


Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping.

Morgan RG, Ives SJ, Walker AE, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ.

J Hypertens. 2014 Jun;32(6):1293-9. doi: 10.1097/HJH.0000000000000157.


Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development.

Donato AJ, Lesniewski LA, Stuart D, Walker AE, Henson G, Sorensen L, Li D, Kohan DE.

Life Sci. 2014 Nov 24;118(2):238-43. doi: 10.1016/j.lfs.2013.12.209. Epub 2014 Jan 8.


The two-way relationship between medical illness and late-life depression.

Gleason OC, Pierce AM, Walker AE, Warnock JK.

Psychiatr Clin North Am. 2013 Dec;36(4):533-44. doi: 10.1016/j.psc.2013.08.003. Epub 2013 Oct 6. Review.


Beneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteries.

Walker AE, Henson GD, Reihl KD, Nielson EI, Morgan RG, Lesniewski LA, Donato AJ.

Age (Dordr). 2014 Apr;36(2):559-69. doi: 10.1007/s11357-013-9585-0. Epub 2013 Sep 25.


Analysis of trafficking, stability and function of human connexin 26 gap junction channels with deafness-causing mutations in the fourth transmembrane helix.

Ambrosi C, Walker AE, Depriest AD, Cone AC, Lu C, Badger J, Skerrett IM, Sosinsky GE.

PLoS One. 2013 Aug 15;8(8):e70916. doi: 10.1371/journal.pone.0070916. eCollection 2013.


Response to effect of fenofibrate on vascular endothelial function: statistical appraisal and its validity.

Walker AE, Kaplon RE, Lucking SM, Russell-Nowlan MJ, Seals DR.

Hypertension. 2013 Jun;61(6):e56. No abstract available.


Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice.

Donato AJ, Walker AE, Magerko KA, Bramwell RC, Black AD, Henson GD, Lawson BR, Lesniewski LA, Seals DR.

Aging Cell. 2013 Oct;12(5):772-83. doi: 10.1111/acel.12103. Epub 2013 Jul 2.


Tadalafil alleviates muscle ischemia in patients with Becker muscular dystrophy.

Martin EA, Barresi R, Byrne BJ, Tsimerinov EI, Scott BL, Walker AE, Gurudevan SV, Anene F, Elashoff RM, Thomas GD, Victor RG.

Sci Transl Med. 2012 Nov 28;4(162):162ra155. doi: 10.1126/scitranslmed.3004327.


Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults.

Walker AE, Kaplon RE, Lucking SM, Russell-Nowlan MJ, Eckel RH, Seals DR.

Hypertension. 2012 Dec;60(6):1517-23. doi: 10.1161/HYPERTENSIONAHA.112.203661. Epub 2012 Oct 29.


Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging.

DeVan AE, Eskurza I, Pierce GL, Walker AE, Jablonski KL, Kaplon RE, Seals DR.

Clin Sci (Lond). 2013 Mar;124(5):325-31. doi: 10.1042/CS20120291.


TNF-α impairs endothelial function in adipose tissue resistance arteries of mice with diet-induced obesity.

Donato AJ, Henson GD, Morgan RG, Enz RA, Walker AE, Lesniewski LA.

Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H672-9. doi: 10.1152/ajpheart.00271.2012. Epub 2012 Jul 20.


Vascular smooth muscle responsiveness to nitric oxide is reduced in healthy adults with increased adiposity.

Christou DD, Pierce GL, Walker AE, Hwang MH, Yoo JK, Luttrell M, Meade TH, English M, Seals DR.

Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H743-50. doi: 10.1152/ajpheart.00394.2012. Epub 2012 Jul 20.


Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study.

Pierce GL, Jablonski KL, Walker AE, Seibert SM, DeVan AE, Black SM, Sharma S, Seals DR.

Am J Hypertens. 2012 Oct;25(10):1050-4. doi: 10.1038/ajh.2012.70. Epub 2012 Jun 7.


Transient bone marrow oedema syndrome in an HIV-infected patient on highly active antiretroviral therapy.

Vera JH, Walker AE, Kinderlerer A, Cooke GS.

Int J STD AIDS. 2012 Mar;23(3):213-5. doi: 10.1258/ijsa.2009.009358.


Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women.

Kaplon RE, Walker AE, Seals DR.

J Appl Physiol (1985). 2011 Nov;111(5):1416-21. doi: 10.1152/japplphysiol.00721.2011. Epub 2011 Sep 8.


25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults.

Jablonski KL, Chonchol M, Pierce GL, Walker AE, Seals DR.

Hypertension. 2011 Jan;57(1):63-9. doi: 10.1161/HYPERTENSIONAHA.110.160929. Epub 2010 Nov 29.


Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults.

Pierce GL, Eskurza I, Walker AE, Fay TN, Seals DR.

Clin Sci (Lond). 2011 Jan;120(1):13-23. doi: 10.1042/CS20100174.


Achieving A-site termination on La(0.18)Sr(0.82)Al(0.59)Ta(0.41)O(3) substrates.

Ngai JH, Schwendemann TC, Walker AE, Segal Y, Walker FJ, Altman EI, Ahn CH.

Adv Mater. 2010 Jul 20;22(26-27):2945-8. doi: 10.1002/adma.200904328. No abstract available.


Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults.

Walker AE, Seibert SM, Donato AJ, Pierce GL, Seals DR.

Hypertension. 2010 Feb;55(2):363-9. doi: 10.1161/HYPERTENSIONAHA.109.145870. Epub 2010 Jan 4.


Habitual exercise and vascular ageing.

Seals DR, Walker AE, Pierce GL, Lesniewski LA.

J Physiol. 2009 Dec 1;587(Pt 23):5541-9. doi: 10.1113/jphysiol.2009.178822. Epub 2009 Sep 1. Review.


Modulation of vascular endothelial function by low-density lipoprotein cholesterol with aging: influence of habitual exercise.

Walker AE, Eskurza I, Pierce GL, Gates PE, Seals DR.

Am J Hypertens. 2009 Mar;22(3):250-6. doi: 10.1038/ajh.2008.353. Epub 2008 Dec 25.


Using an economic model of diabetes to evaluate prevention and care strategies in Australia.

Colagiuri S, Walker AE.

Health Aff (Millwood). 2008 Jan-Feb;27(1):256-68. doi: 10.1377/hlthaff.27.1.256.


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