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A shared protocol for porcine surfactant use in pediatric acute respiratory distress syndrome: a feasibility study.

Wolfler A, Piastra M, Amigoni A, Santuz P, Gitto E, Rossetti E, Tinelli C, Montani C, Savron F, Pizzi S, D'amato L, Mondardini MC, Conti G, De Silvestri A.

BMC Pediatr. 2019 Jun 18;19(1):203. doi: 10.1186/s12887-019-1579-3.


Loss of RAF kinase inhibitor protein is involved in myelomonocytic differentiation and aggravates RAS-driven myeloid leukemogenesis.

Caraffini V, Geiger O, Rosenberger A, Hatzl S, Perfler B, Berg JL, Lim C, Strobl H, Kashofer K, Schauer S, Beham-Schmid C, Hoefler G, Geissler K, Quehenberger F, Kolch W, Athineos D, Blyth K, Wölfler A, Sill H, Zebisch A.

Haematologica. 2019 May 16. pii: haematol.2018.209650. doi: 10.3324/haematol.2018.209650. [Epub ahead of print]


Detection of AML-specific TP53 mutations in bone marrow-derived mesenchymal stromal cells cultured under hypoxia conditions.

Müller M, Graf R, Kashofer K, Macher S, Wölfler A, Zebisch A, Hrzenjak A, Heitzer E, Sill H.

Ann Hematol. 2019 Aug;98(8):2019-2020. doi: 10.1007/s00277-019-03680-4. Epub 2019 Apr 2. No abstract available.


High GPR56 surface expression correlates with a leukemic stem cell gene signature in CD34-positive AML.

Daga S, Rosenberger A, Quehenberger F, Krisper N, Prietl B, Reinisch A, Zebisch A, Sill H, Wölfler A.

Cancer Med. 2019 Apr;8(4):1771-1778. doi: 10.1002/cam4.2053. Epub 2019 Mar 7.


Correction to: Ruxolitinib therapy formyelofibrosis in Austria : Consensus on therapy management.

Krauth MT, Burgstaller S, Buxhofer-Ausch V, Gastl G, Geissler K, Keil F, Krippl P, Melchardt T, Petzer A, Rumpold H, Sliwa T, Wöhrer S, Wölfler A, Gisslinger H.

Wien Klin Wochenschr. 2019 Jan;131(1-2):47. doi: 10.1007/s00508-018-1428-7.


The infant with severe bronchiolitis: from high flow nasal cannula to continuous positive airway pressure and mechanical ventilation.

Wolfler A, Raimondi G, Pagan de Paganis C, Zoia E.

Minerva Pediatr. 2018 Dec;70(6):612-622. doi: 10.23736/S0026-4946.18.05358-6. Epub 2018 Oct 18. Review.


Clinical implications of subclonal TP53 mutations in acute myeloid leukemia.

Prochazka KT, Pregartner G, Rücker FG, Heitzer E, Pabst G, Wölfler A, Zebisch A, Berghold A, Döhner K, Sill H.

Haematologica. 2019 Mar;104(3):516-523. doi: 10.3324/haematol.2018.205013. Epub 2018 Oct 11.


Feasibility and safety of using an automated decision support system for insulin therapy in the treatment of steroid-induced hyperglycemia in patients with acute graft-versus-host disease: A randomized trial.

Aberer F, Mader JK, Holzgruber J, Trummer C, Schwetz V, Pandis M, Pferschy PN, Greinix H, Tripolt NJ, Pieber TR, Zebisch A, Sill H, Wölfler A, Sourij H.

J Diabetes Investig. 2019 Mar;10(2):339-342. doi: 10.1111/jdi.12919. Epub 2018 Oct 1.


Ruxolitinib therapy for myelofibrosis in Austria : Consensus on therapy management.

Krauth MT, Burgstaller S, Buxhofer-Ausch V, Gastl G, Geissler K, Keil F, Krippl P, Melchardt T, Petzer A, Rumpold H, Sliwa T, Wöhrer S, Wölfler A, Gisslinger H.

Wien Klin Wochenschr. 2018 Sep;130(17-18):495-504. doi: 10.1007/s00508-018-1365-5. Epub 2018 Jul 24. Erratum in: Wien Klin Wochenschr. 2019 Jan;131(1-2):47.


Austrian recommendations for the management of polycythemia vera.

Burgstaller S, Buxhofer-Ausch V, Sliwa T, Beham-Schmid C, Gastl G, Geissler K, Melchardt T, Krauth M, Krippl P, Petzer A, Rumpold H, Wölfler A, Gisslinger H.

Wien Klin Wochenschr. 2018 Sep;130(17-18):535-542. doi: 10.1007/s00508-018-1359-3. Epub 2018 Jul 19.


Diagnosis of invasive aspergillosis in hematological malignancy patients: Performance of cytokines, Asp LFD, and Aspergillus PCR in same day blood and bronchoalveolar lavage samples.

Heldt S, Prattes J, Eigl S, Spiess B, Flick H, Rabensteiner J, Johnson G, Prüller F, Wölfler A, Niedrist T, Boch T, Neumeister P, Strohmaier H, Krause R, Buchheidt D, Hoenigl M.

J Infect. 2018 Sep;77(3):235-241. doi: 10.1016/j.jinf.2018.05.001. Epub 2018 Jul 1.


Antifungal Prophylaxis with Posaconazole Delayed-Release Tablet and Oral Suspension in a Real-Life Setting: Plasma Levels, Efficacy, and Tolerability.

Lenczuk D, Zinke-Cerwenka W, Greinix H, Wölfler A, Prattes J, Zollner-Schwetz I, Valentin T, Lin TC, Meinitzer A, Hoenigl M, Krause R.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e02655-17. doi: 10.1128/AAC.02655-17. Print 2018 Jun.


Non-invasive ventilation practices in children across Europe.

Mayordomo-Colunga J, Pons-Òdena M, Medina A, Rey C, Milesi C, Kallio M, Wolfler A, García-Cuscó M, Demirkol D, García-López M, Rimensberger P.

Pediatr Pulmonol. 2018 Aug;53(8):1107-1114. doi: 10.1002/ppul.23988. Epub 2018 Mar 24.


Visceral leishmaniasis in a patient with diabetes mellitus type 2 and discrete bicytopenia.

Schwetz V, Trummer C, Friedl C, Beham-Schmid C, Kulnik R, Wölfler A, Horvath K, Wunsch S, Prattes J, Zollner-Schwetz I, Pieber TR, Mader JK, Krause R.

Clin Case Rep. 2017 Nov 28;6(1):78-81. doi: 10.1002/ccr3.1259. eCollection 2018 Jan.


Loss of RKIP is a frequent event in myeloid sarcoma and promotes leukemic tissue infiltration.

Caraffini V, Perfler B, Berg JL, Uhl B, Schauer S, Kashofer K, Ghaffari-Tabrizi-Wizsy N, Strobl H, Wölfler A, Hoefler G, Sill H, Zebisch A.

Blood. 2018 Feb 15;131(7):826-830. doi: 10.1182/blood-2017-09-804906. Epub 2018 Jan 2. No abstract available.


Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies.

Cooney JD, Lin AP, Jiang D, Wang L, Suhasini AN, Myers J, Qiu Z, Wölfler A, Sill H, Aguiar RCT.

Clin Cancer Res. 2018 Mar 1;24(5):1103-1113. doi: 10.1158/1078-0432.CCR-17-2218. Epub 2017 Dec 15.


Essential thrombocythemia vs. pre-fibrotic/early primary myelofibrosis: discrimination by laboratory and clinical data.

Schalling M, Gleiss A, Gisslinger B, Wölfler A, Buxhofer-Ausch V, Jeryczynski G, Krauth MT, Simonitsch-Klupp I, Beham-Schmid C, Thiele J, Gisslinger H.

Blood Cancer J. 2017 Dec 13;7(12):643. doi: 10.1038/s41408-017-0006-y. No abstract available.


Real-world challenges and unmet needs in the diagnosis and treatment of suspected invasive pulmonary aspergillosis in patients with haematological diseases: An illustrative case study.

Hoenigl M, Prattes J, Neumeister P, Wölfler A, Krause R.

Mycoses. 2018 Mar;61(3):201-205. doi: 10.1111/myc.12727. Epub 2017 Nov 22.


Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia.

Gaksch L, Kashofer K, Heitzer E, Quehenberger F, Daga S, Hofer S, Halbwedl I, Graf R, Krisper N, Hoefler G, Zebisch A, Sill H, Wölfler A.

Am J Hematol. 2018 Jan;93(1):23-30. doi: 10.1002/ajh.24922. Epub 2017 Oct 19.


Levels of interleukin (IL)-6 and IL-8 are elevated in serum and bronchoalveolar lavage fluid of haematological patients with invasive pulmonary aspergillosis.

Heldt S, Eigl S, Prattes J, Flick H, Rabensteiner J, Prüller F, Niedrist T, Neumeister P, Wölfler A, Strohmaier H, Krause R, Hoenigl M.

Mycoses. 2017 Dec;60(12):818-825. doi: 10.1111/myc.12679. Epub 2017 Sep 6.


The frequency of occurrence of fish-shaped red blood cells in different haematologic disorders.

Robier C, Körber C, Quehenberger F, Neubauer M, Wölfler A.

Clin Chem Lab Med. 2018 Jan 26;56(2):323-326. doi: 10.1515/cclm-2017-0378.


Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis.

Magina KN, Pregartner G, Zebisch A, Wölfler A, Neumeister P, Greinix HT, Berghold A, Sill H.

Blood. 2017 Aug 17;130(7):946-948. doi: 10.1182/blood-2017-04-777722. Epub 2017 Jul 5. Review. No abstract available.


Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing.

Kashofer K, Gornicec M, Lind K, Caraffini V, Schauer S, Beham-Schmid C, Wölfler A, Hoefler G, Sill H, Zebisch A.

Leuk Lymphoma. 2018 Feb;59(2):501-504. doi: 10.1080/10428194.2017.1339879. Epub 2017 Jun 20. No abstract available.


Pre-fibrotic/early primary myelofibrosis vs. WHO-defined essential thrombocythemia: The impact of minor clinical diagnostic criteria on the outcome of the disease.

Jeryczynski G, Thiele J, Gisslinger B, Wölfler A, Schalling M, Gleiß A, Burgstaller S, Buxhofer-Ausch V, Sliwa T, Schlögl E, Geissler K, Krauth MT, Nader A, Vesely M, Simonitsch-Klupp I, Müllauer L, Beham-Schmid C, Gisslinger H.

Am J Hematol. 2017 Sep;92(9):885-891. doi: 10.1002/ajh.24788. Epub 2017 Jun 9.


Early Hyperglycemia after Initiation of Glucocorticoid Therapy Predicts Adverse Outcome in Patients with Acute Graft-versus-Host Disease.

Stauber MN, Aberer F, Oulhaj A, Mader JK, Zebisch A, Pieber TR, Neumeister P, Greinix HT, Sill H, Sourij H, Wölfler A.

Biol Blood Marrow Transplant. 2017 Jul;23(7):1186-1192. doi: 10.1016/j.bbmt.2017.03.010. Epub 2017 Mar 8.


Hyperglycaemia within the first month after allogeneic haematopoietic stem-cell transplantation is an independent risk factor for overall survival in patients with acute myeloid leukaemia.

Aberer F, Kremser S, Mader JK, Zinke-Cerwenka W, Greinix H, Tripolt NJ, Pieber TR, Zebisch A, Sill H, Oulhaj A, Sourij H, Wölfler A.

Diabetes Metab. 2017 Dec;43(6):560-562. doi: 10.1016/j.diabet.2017.02.001. Epub 2017 Mar 6. No abstract available.


Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia.

Lal R, Lind K, Heitzer E, Ulz P, Aubell K, Kashofer K, Middeke JM, Thiede C, Schulz E, Rosenberger A, Hofer S, Feilhauer B, Rinner B, Svendova V, Schimek MG, Rücker FG, Hoefler G, Döhner K, Zebisch A, Wölfler A, Sill H.

Blood. 2017 May 4;129(18):2587-2591. doi: 10.1182/blood-2016-11-751008. Epub 2017 Mar 3. No abstract available.


Clinical impact of bone marrow morphology for the diagnosis of essential thrombocythemia: comparison between the BCSH and the WHO criteria.

Gisslinger H, Jeryczynski G, Gisslinger B, Wölfler A, Burgstaller S, Buxhofer-Ausch V, Schalling M, Krauth MT, Schiefer AI, Kornauth C, Simonitsch-Klupp I, Beham-Schmid C, Müllauer L, Thiele J.

Leukemia. 2017 Mar;31(3):774-775. doi: 10.1038/leu.2016.291. No abstract available.


Withdrawal Assessment Tool-1 Monitoring in PICU: A Multicenter Study on Iatrogenic Withdrawal Syndrome.

Amigoni A, Mondardini MC, Vittadello I, Zaglia F, Rossetti E, Vitale F, Ferrario S, Savron F, Coffaro G, Brugnaro L, Amato R, Wolfler A, Franck LS; Network of Paediatric Intensive Care Unit Study Group (TIPNet).

Pediatr Crit Care Med. 2017 Feb;18(2):e86-e91. doi: 10.1097/PCC.0000000000001054.


EMpowerment of PArents in THe Intensive Care Questionnaire: Translation and Validation in Italian PICUs.

Wolfler A, Giannini A, Finistrella M, Salvo I, Calderini E, Frasson G, Dall'Oglio I, Di Furia M, Iuzzolino R, Musicco M, Latour JM.

Pediatr Crit Care Med. 2017 Feb;18(2):e77-e85. doi: 10.1097/PCC.0000000000001031.


Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs.

Zebisch A, Hatzl S, Pichler M, Wölfler A, Sill H.

Int J Mol Sci. 2016 Dec 10;17(12). pii: E2080. Review.


Austrian recommendations for the management of primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis: an expert statement.

Sliwa T, Beham-Schmid C, Burgstaller S, Buxhofer-Ausch V, Gastl G, Geissler K, Krauth M, Krippl P, Lang A, Petzer A, Wöhrer S, Wölfler A, Gisslinger H.

Wien Klin Wochenschr. 2017 May;129(9-10):293-302. doi: 10.1007/s00508-016-1120-8. Epub 2016 Dec 13.


Response to Harrison et al. 'Clinically relevant differences between BCSH and WHO diagnostic criteria for ET'.

Gisslinger H, Jeryczynski G, Wölfler A, Beham-Schmid C, Thiele J.

Leukemia. 2017 Mar;31(3):768-769. doi: 10.1038/leu.2016.319. Epub 2016 Nov 29. No abstract available.


Evidence for a role of decitabine in the treatment of myeloid sarcoma.

Gornicec M, Wölfler A, Stanzel S, Sill H, Zebisch A.

Ann Hematol. 2017 Mar;96(3):505-506. doi: 10.1007/s00277-016-2870-0. Epub 2016 Nov 6. No abstract available.


Acute myeloid leukemia with TP53 germ line mutations.

Zebisch A, Lal R, Müller M, Lind K, Kashofer K, Girschikofsky M, Fuchs D, Wölfler A, Geigl JB, Sill H.

Blood. 2016 Nov 3;128(18):2270-2272. Epub 2016 Sep 12. No abstract available.


Galactomannan testing and Aspergillus PCR in same-day bronchoalveolar lavage and blood samples for diagnosis of invasive aspergillosis.

Eigl S, Hoenigl M, Spiess B, Heldt S, Prattes J, Neumeister P, Wolfler A, Rabensteiner J, Prueller F, Krause R, Reinwald M, Flick H, Buchheidt D, Boch T.

Med Mycol. 2017 Jul 1;55(5):528-534. doi: 10.1093/mmy/myw102.


Efficacy of ketamine in refractory convulsive status epilepticus in children: a protocol for a sequential design, multicentre, randomised, controlled, open-label, non-profit trial (KETASER01).

Rosati A, Ilvento L, L'Erario M, De Masi S, Biggeri A, Fabbro G, Bianchi R, Stoppa F, Fusco L, Pulitanò S, Battaglia D, Pettenazzo A, Sartori S, Biban P, Fontana E, Cesaroni E, Mora D, Costa P, Meleleo R, Vittorini R, Conio A, Wolfler A, Mastrangelo M, Mondardini MC, Franzoni E, McGreevy KS, Di Simone L, Pugi A, Mirabile L, Vigevano F, Guerrini R.

BMJ Open. 2016 Jun 15;6(6):e011565. doi: 10.1136/bmjopen-2016-011565.


Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.

Hatzl S, Geiger O, Kuepper MK, Caraffini V, Seime T, Furlan T, Nussbaumer E, Wieser R, Pichler M, Scheideler M, Nowek K, Jongen-Lavrencic M, Quehenberger F, Wölfler A, Troppmair J, Sill H, Zebisch A.

Cancer Res. 2016 Jun 15;76(12):3644-54. doi: 10.1158/0008-5472.CAN-15-3049. Epub 2016 Apr 15.


Venous thromboembolism in a patient with persistent inhibitor to coagulation factor V - a case report.

Rief P, Hackl G, Hafner F, Raggam RB, Wölfler A, Brodmann M, Gary T.

Clin Chem Lab Med. 2016 Sep 1;54(9):e269-71. doi: 10.1515/cclm-2015-1103. No abstract available.


Infections in patients with acute myeloid leukemia treated with low-intensity therapeutic regimens: Risk factors and efficacy of antibiotic prophylaxis.

Bainschab A, Quehenberger F, Greinix HT, Krause R, Wölfler A, Sill H, Zebisch A.

Leuk Res. 2016 Mar;42:47-51. doi: 10.1016/j.leukres.2016.01.014. Epub 2016 Feb 1.


The Importance of Mortality Risk Assessment: Validation of the Pediatric Index of Mortality 3 Score.

Wolfler A, Osello R, Gualino J, Calderini E, Vigna G, Santuz P, Amigoni A, Savron F, Caramelli F, Rossetti E, Cecchetti C, Corbari M, Piastra M, Testa R, Coffaro G, Stancanelli G, Gitto E, Amato R, Prinelli F, Salvo I; Pediatric Intensive Therapy Network (TIPNet) Study Group.

Pediatr Crit Care Med. 2016 Mar;17(3):251-6. doi: 10.1097/PCC.0000000000000657.


Chemotherapy-Induced Intestinal Mucosal Barrier Damage: a Cause of Falsely Elevated Serum 1,3-Beta-d-Glucan Levels?

Prattes J, Raggam RB, Vanstraelen K, Rabensteiner J, Hoegenauer C, Krause R, Prüller F, Wölfler A, Spriet I, Hoenigl M.

J Clin Microbiol. 2016 Mar;54(3):798-801. doi: 10.1128/JCM.02972-15. Epub 2015 Dec 30.


Clinical impact of bone marrow morphology for the diagnosis of essential thrombocythemia: comparison between the BCSH and the WHO criteria.

Gisslinger H, Jeryczynski G, Gisslinger B, Wölfler A, Burgstaller S, Buxhofer-Ausch V, Schalling M, Krauth MT, Schiefer AI, Kornauth C, Simonitsch-Klupp I, Beham-Schmid C, Müllauer L, Thiele J.

Leukemia. 2016 May;30(5):1126-32. doi: 10.1038/leu.2015.360. Epub 2015 Dec 29. Erratum in: Leukemia. 2017 Mar;31(3):774-775.


Urine Galactomannan-to-Creatinine Ratio for Detection of Invasive Aspergillosis in Patients with Hematological Malignancies.

Reischies FM, Raggam RB, Prattes J, Krause R, Eigl S, List A, Quehenberger F, Strenger V, Wölfler A, Hoenigl M.

J Clin Microbiol. 2016 Mar;54(3):771-4. doi: 10.1128/JCM.02969-15. Epub 2015 Dec 23.


Prognostic potential of 1,3-beta-d-glucan levels in bronchoalveolar lavage fluid samples.

Reischies FM, Prattes J, Prüller F, Eigl S, List A, Wölfler A, Buzina W, Zollner-Schwetz I, Valentin T, Rabensteiner J, Flick H, Krause R, Raggam RB, Hoenigl M.

J Infect. 2016 Jan;72(1):29-35. doi: 10.1016/j.jinf.2015.09.016. Epub 2015 Sep 28.


Deletion of SPRY4 is a frequent event in secondary acute myeloid leukemia.

Geiger O, Hatzl S, Kashofer K, Hoefler G, Wölfler A, Sill H, Zebisch A.

Ann Hematol. 2015 Nov;94(11):1923-4. doi: 10.1007/s00277-015-2445-5. Epub 2015 Jul 25. No abstract available.


Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.

Schlager S, Goeritzer M, Jandl K, Frei R, Vujic N, Kolb D, Strohmaier H, Dorow J, Eichmann TO, Rosenberger A, Wölfler A, Lass A, Kershaw EE, Ceglarek U, Dichlberger A, Heinemann A, Kratky D.

J Leukoc Biol. 2015 Nov;98(5):837-50. doi: 10.1189/jlb.3A0515-206R. Epub 2015 Jun 24.


Diagnostic accuracy of the Aspergillus-specific bronchoalveolar lavage lateral-flow assay in haematological malignancy patients.

Prattes J, Lackner M, Eigl S, Reischies F, Raggam RB, Koidl C, Flick H, Wurm R, Palfner M, Wölfler A, Neumeister P, Thornton CR, Krause R, Lass-Flörl C, Hoenigl M.

Mycoses. 2015 Aug;58(8):461-9. doi: 10.1111/myc.12343. Epub 2015 Jun 23.


Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair: Data from the General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes.

Frawley G, Bell G, Disma N, Withington DE, de Graaff JC, Morton NS, McCann ME, Arnup SJ, Bagshaw O, Wolfler A, Bellinger D, Davidson AJ; General Anesthesia compared to Spinal anesthesia (GAS) Consortium.

Anesthesiology. 2015 Jul;123(1):55-65. doi: 10.1097/ALN.0000000000000708.


Detection of (1→3)-β-D-glucan in same-day urine and serum samples obtained from patients with haematological malignancies.

Raggam RB, Fischbach LM, Prattes J, Duettmann W, Eigl S, Reischies F, Wölfler A, Rabensteiner J, Prueller F, Krause R, Hoenigl M.

Mycoses. 2015 Jul;58(7):394-8. doi: 10.1111/myc.12328. Epub 2015 May 11.


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