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Items: 40

1.

Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics.

Storck EM, Morales-Sanfrutos J, Serwa RA, Panyain N, Lanyon-Hogg T, Tolmachova T, Ventimiglia LN, Martin-Serrano J, Seabra MC, Wojciak-Stothard B, Tate EW.

Nat Chem. 2019 Jun;11(6):552-561. doi: 10.1038/s41557-019-0237-6. Epub 2019 Apr 1.

2.

CLIC4/Arf6 Pathway.

Abdul-Salam VB, Russomanno G, Chien-Nien C, Mahomed AS, Yates LA, Wilkins MR, Zhao L, Gierula M, Dubois O, Schaeper U, Endruschat J, Wojciak-Stothard B.

Circ Res. 2019 Jan 4;124(1):52-65. doi: 10.1161/CIRCRESAHA.118.313705.

3.

Nanoscale tweezers for single-cell biopsies.

Nadappuram BP, Cadinu P, Barik A, Ainscough AJ, Devine MJ, Kang M, Gonzalez-Garcia J, Kittler JT, Willison KR, Vilar R, Actis P, Wojciak-Stothard B, Oh SH, Ivanov AP, Edel JB.

Nat Nanotechnol. 2019 Jan;14(1):80-88. doi: 10.1038/s41565-018-0315-8. Epub 2018 Dec 3.

4.

Tipifarnib prevents development of hypoxia-induced pulmonary hypertension.

Duluc L, Ahmetaj-Shala B, Mitchell J, Abdul-Salam VB, Mahomed AS, Aldabbous L, Oliver E, Iannone L, Dubois OD, Storck EM, Tate EW, Zhao L, Wilkins MR, Wojciak-Stothard B.

Cardiovasc Res. 2017 Mar 1;113(3):276-287. doi: 10.1093/cvr/cvw258.

5.

Neutrophil Extracellular Traps Promote Angiogenesis: Evidence From Vascular Pathology in Pulmonary Hypertension.

Aldabbous L, Abdul-Salam V, McKinnon T, Duluc L, Pepke-Zaba J, Southwood M, Ainscough AJ, Hadinnapola C, Wilkins MR, Toshner M, Wojciak-Stothard B.

Arterioscler Thromb Vasc Biol. 2016 Oct;36(10):2078-87. doi: 10.1161/ATVBAHA.116.307634. Epub 2016 Jul 28.

6.

A New NO-Releasing Nanoformulation for the Treatment of Pulmonary Arterial Hypertension.

Mohamed NA, Ahmetaj-Shala B, Duluc L, Mackenzie LS, Kirkby NS, Reed DM, Lickiss PD, Davies RP, Freeman GR, Wojciak-Stothard B, Chester AH, El-Sherbiny IM, Mitchell JA, Yacoub MH.

J Cardiovasc Transl Res. 2016 Apr;9(2):162-4. doi: 10.1007/s12265-016-9684-2. Epub 2016 Mar 9.

7.

Endothelium-derived microparticles from chronically thromboembolic pulmonary hypertensive patients facilitate endothelial angiogenesis.

Belik D, Tsang H, Wharton J, Howard L, Bernabeu C, Wojciak-Stothard B.

J Biomed Sci. 2016 Jan 19;23:4. doi: 10.1186/s12929-016-0224-9.

8.

miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.

Iannone L, Zhao L, Dubois O, Duluc L, Rhodes CJ, Wharton J, Wilkins MR, Leiper J, Wojciak-Stothard B.

Biochem J. 2014 Aug 15;462(1):103-12. doi: 10.1042/BJ20140486.

PMID:
24895913
9.

Role of asymmetric methylarginine and connexin 43 in the regulation of pulmonary endothelial function.

Tsang H, Leiper J, Hou Lao K, Dowsett L, Delahaye MW, Barnes G, Wharton J, Howard L, Iannone L, Lang NN, Wilkins MR, Wojciak-Stothard B.

Pulm Circ. 2013 Sep;3(3):675-91. doi: 10.1086/674440. Epub 2013 Dec 4.

10.

Rho GTPases in the regulation of pulmonary vascular barrier function.

Duluc L, Wojciak-Stothard B.

Cell Tissue Res. 2014 Mar;355(3):675-85. doi: 10.1007/s00441-014-1805-0. Epub 2014 Mar 6. Review.

PMID:
24599334
11.

Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.

Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR, Edwards JC, Yuspa SH, Howard LS, Edwards RJ, Rhodes CJ, Gibbs JS, Wharton J, Zhao L, Wilkins MR.

Circulation. 2014 Apr 29;129(17):1770-80. doi: 10.1161/CIRCULATIONAHA.113.006797. Epub 2014 Feb 6.

12.

Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.

Rhodes CJ, Wharton J, Boon RA, Roexe T, Tsang H, Wojciak-Stothard B, Chakrabarti A, Howard LS, Gibbs JS, Lawrie A, Condliffe R, Elliot CA, Kiely DG, Huson L, Ghofrani HA, Tiede H, Schermuly R, Zeiher AM, Dimmeler S, Wilkins MR.

Am J Respir Crit Care Med. 2013 Feb 1;187(3):294-302. doi: 10.1164/rccm.201205-0839OC. Epub 2012 Dec 6.

PMID:
23220912
13.

Rho GTPases in pulmonary vascular dysfunction.

Storck EM, Wojciak-Stothard B.

Vascul Pharmacol. 2013 Mar;58(3):202-10. doi: 10.1016/j.vph.2012.09.004. Epub 2012 Sep 13. Review.

PMID:
22982942
14.

Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia.

Wojciak-Stothard B, Zhao L, Oliver E, Dubois O, Wu Y, Kardassis D, Vasilaki E, Huang M, Mitchell JA, Harrington LS, Prendergast GC, Wilkins MR.

Circ Res. 2012 May 25;110(11):1423-34. doi: 10.1161/CIRCRESAHA.112.264473. Epub 2012 Apr 26. Erratum in: Circ Res. 2012 Aug 17;111(5):e163. Louise, Harrington [corrected to Harrington, Louise S].

15.

Endothelial cell migration under flow.

Wojciak-Stothard B.

Methods Mol Biol. 2011;769:137-47. doi: 10.1007/978-1-61779-207-6_10.

PMID:
21748674
16.

Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives.

Lichtenstein MP, Carriba P, Baltrons MA, Wojciak-Stothard B, Peterson JR, García A, Galea E.

J Alzheimers Dis. 2010;22(4):1135-55. doi: 10.3233/JAD-2010-101332.

PMID:
20930267
17.

Adenoviral-mediated overexpression of DDAH improves vascular tone regulation.

Torondel B, Nandi M, Kelly P, Wojciak-Stothard B, Fleming I, Leiper J.

Vasc Med. 2010 Jun;15(3):205-13. doi: 10.1177/1358863X09360264. Epub 2010 Mar 10.

PMID:
20219849
18.

Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells.

Takesono A, Heasman SJ, Wojciak-Stothard B, Garg R, Ridley AJ.

PLoS One. 2010 Jan 19;5(1):e8774. doi: 10.1371/journal.pone.0008774.

19.

The DDAH/ADMA pathway in the control of endothelial cell migration and angiogenesis.

Fiedler LR, Wojciak-Stothard B.

Biochem Soc Trans. 2009 Dec;37(Pt 6):1243-7. doi: 10.1042/BST0371243. Review.

PMID:
19909255
20.

Simvastatin and sildenafil combine to attenuate pulmonary hypertension.

Zhao L, Sebkhi A, Ali O, Wojciak-Stothard B, Mamanova L, Yang Q, Wharton J, Wilkins MR.

Eur Respir J. 2009 Oct;34(4):948-57. doi: 10.1183/09031936.00143508.

21.

The ADMA/DDAH pathway regulates VEGF-mediated angiogenesis.

Fiedler LR, Bachetti T, Leiper J, Zachary I, Chen L, Renné T, Wojciak-Stothard B.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2117-24. doi: 10.1161/ATVBAHA.109.194035. Epub 2009 Sep 24.

22.

Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function.

Wojciak-Stothard B, Torondel B, Zhao L, Renné T, Leiper JM.

Mol Biol Cell. 2009 Jan;20(1):33-42. doi: 10.1091/mbc.E08-04-0395. Epub 2008 Oct 15.

23.

New drug targets for pulmonary hypertension: Rho GTPases in pulmonary vascular remodelling.

Wojciak-Stothard B.

Postgrad Med J. 2008 Jul;84(993):348-53. doi: 10.1136/pgmj.2007.066555. Review.

PMID:
18716013
24.

Rho GTPases and hypoxia in pulmonary vascular endothelial cells.

Wojciak-Stothard B, Leiper J.

Methods Enzymol. 2008;439:267-83. doi: 10.1016/S0076-6879(07)00420-X.

PMID:
18374171
25.

Regulation of endothelial barrier function during flow-induced conversion to an arterial phenotype.

Seebach J, Donnert G, Kronstein R, Werth S, Wojciak-Stothard B, Falzarano D, Mrowietz C, Hell SW, Schnittler HJ.

Cardiovasc Res. 2007 Aug 1;75(3):596-607. Epub 2007 May 4.

PMID:
17531214
26.

The ADMA/DDAH pathway is a critical regulator of endothelial cell motility.

Wojciak-Stothard B, Torondel B, Tsang LY, Fleming I, Fisslthaler B, Leiper JM, Vallance P.

J Cell Sci. 2007 Mar 15;120(Pt 6):929-42. Epub 2007 Feb 27. Erratum in: J Cell Sci. 2007 Apr 15;120(Pt 8):1502.

27.

Disruption of methylarginine metabolism impairs vascular homeostasis.

Leiper J, Nandi M, Torondel B, Murray-Rust J, Malaki M, O'Hara B, Rossiter S, Anthony S, Madhani M, Selwood D, Smith C, Wojciak-Stothard B, Rudiger A, Stidwill R, McDonald NQ, Vallance P.

Nat Med. 2007 Feb;13(2):198-203. Epub 2007 Feb 4.

PMID:
17273169
28.

Rac1 and RhoA as regulators of endothelial phenotype and barrier function in hypoxia-induced neonatal pulmonary hypertension.

Wojciak-Stothard B, Tsang LY, Paleolog E, Hall SM, Haworth SG.

Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1173-82. Epub 2006 Jan 20.

29.

Tyrosine phosphorylation and the small GTPase rac cross-talk in regulation of endothelial barrier function.

Seebach J, Mädler HJ, Wojciak-Stothard B, Schnittler HJ.

Thromb Haemost. 2005 Sep;94(3):620-9.

PMID:
16268481
30.

Perinatal changes in pulmonary vascular endothelial function.

Wojciak-Stothard B, Haworth SG.

Pharmacol Ther. 2006 Jan;109(1-2):78-91. Epub 2005 Jul 28. Review.

PMID:
16054700
31.

Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells.

Wojciak-Stothard B, Tsang LY, Haworth SG.

Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L749-60. Epub 2004 Dec 10.

32.

Rho GTPases and the regulation of endothelial permeability.

Wojciak-Stothard B, Ridley AJ.

Vascul Pharmacol. 2002 Nov;39(4-5):187-99. Review.

PMID:
12747959
33.
34.

Rho and Rac but not Cdc42 regulate endothelial cell permeability.

Wójciak-Stothard B, Potempa S, Eichholtz T, Ridley AJ.

J Cell Sci. 2001 Apr;114(Pt 7):1343-55.

35.

Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering.

Wójciak-Stothard B, Williams L, Ridley AJ.

J Cell Biol. 1999 Jun 14;145(6):1293-307.

36.
37.

Adhesion, orientation, and movement of cells cultured on ultrathin fibronectin fibers.

Wòjciak-Stothard B, Denyer M, Mishra M, Brown RA.

In Vitro Cell Dev Biol Anim. 1997 Feb;33(2):110-7.

PMID:
9081218
38.

Guidance and activation of murine macrophages by nanometric scale topography.

Wójciak-Stothard B, Curtis A, Monaghan W, MacDonald K, Wilkinson C.

Exp Cell Res. 1996 Mar 15;223(2):426-35.

PMID:
8601420
39.

Activation of macrophage-like cells by multiple grooved substrata. Topographical control of cell behaviour.

Wójciak-Stothard B, Madeja Z, Korohoda W, Curtis A, Wilkinson C.

Cell Biol Int. 1995 Jun;19(6):485-90.

PMID:
7640662
40.

Role of the cytoskeleton in the reaction of fibroblasts to multiple grooved substrata.

Wójciak-Stothard B, Curtis AS, Monaghan W, McGrath M, Sommer I, Wilkinson CD.

Cell Motil Cytoskeleton. 1995;31(2):147-58.

PMID:
7553908

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