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Items: 19


Wiskott-Aldrich syndrome protein senses irradiation-induced DNA damage to coordinate the cell-protective Golgi dispersal response in human T and B lymphocytes.

Wen KK, Han SS, Vyas YM.

J Allergy Clin Immunol. 2019 Oct 9. pii: S0091-6749(19)31263-1. doi: 10.1016/j.jaci.2019.09.026. [Epub ahead of print]


R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome.

Sarkar K, Han SS, Wen KK, Ochs HD, Dupré L, Seidman MM, Vyas YM.

J Allergy Clin Immunol. 2018 Jul;142(1):219-234. doi: 10.1016/j.jaci.2017.11.023. Epub 2017 Dec 15.


SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells.

Sarkar K, Sadhukhan S, Han SS, Vyas YM.

Blood. 2015 Oct 1;126(14):1670-82. doi: 10.1182/blood-2015-05-646182. Epub 2015 Aug 10.


Disruption of hSWI/SNF complexes in T cells by WAS mutations distinguishes X-linked thrombocytopenia from Wiskott-Aldrich syndrome.

Sarkar K, Sadhukhan S, Han SS, Vyas YM.

Blood. 2014 Nov 27;124(23):3409-19. doi: 10.1182/blood-2014-07-587642. Epub 2014 Sep 24.


Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization.

Sadhukhan S, Sarkar K, Taylor M, Candotti F, Vyas YM.

J Immunol. 2014 Jul 1;193(1):150-60. doi: 10.4049/jimmunol.1302923. Epub 2014 May 28.


Congenital dyserythropoietic anemia type I presenting as persistent pulmonary hypertension with pigeon chest deformity.

El-Sheikh AA, Hashem H, Holman C, Vyas YM.

Pediatr Blood Cancer. 2014 Aug;61(8):1460-2. doi: 10.1002/pbc.24945. Epub 2014 Jan 13.


Mifamurtide in metastatic and recurrent osteosarcoma: a patient access study with pharmacokinetic, pharmacodynamic, and safety assessments.

Anderson PM, Meyers P, Kleinerman E, Venkatakrishnan K, Hughes DP, Herzog C, Huh W, Sutphin R, Vyas YM, Shen V, Warwick A, Yeager N, Oliva C, Wang B, Liu Y, Chou A.

Pediatr Blood Cancer. 2014 Feb;61(2):238-44. doi: 10.1002/pbc.24686. Epub 2013 Aug 31.


Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis.

Kreindler JL, Steele C, Nguyen N, Chan YR, Pilewski JM, Alcorn JF, Vyas YM, Aujla SJ, Finelli P, Blanchard M, Zeigler SF, Logar A, Hartigan E, Kurs-Lasky M, Rockette H, Ray A, Kolls JK.

J Clin Invest. 2010 Sep;120(9):3242-54. doi: 10.1172/JCI42388. Epub 2010 Aug 16.


Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.

Taylor MD, Sadhukhan S, Kottangada P, Ramgopal A, Sarkar K, D'Silva S, Selvakumar A, Candotti F, Vyas YM.

Sci Transl Med. 2010 Jun 23;2(37):37ra44. doi: 10.1126/scitranslmed.3000813.


Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis.

Park JW, Kim HP, Lee SJ, Wang X, Wang Y, Ifedigbo E, Watkins SC, Ohba M, Ryter SW, Vyas YM, Choi AM.

J Immunol. 2008 Apr 1;180(7):4668-78.


Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells.

Arora M, Chen L, Paglia M, Gallagher I, Allen JE, Vyas YM, Ray A, Ray P.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7777-82. Epub 2006 May 8.


Treatment of osteosarcoma at first recurrence after contemporary therapy: the Memorial Sloan-Kettering Cancer Center experience.

Chou AJ, Merola PR, Wexler LH, Gorlick RG, Vyas YM, Healey JH, LaQuaglia MP, Huvos AG, Meyers PA.

Cancer. 2005 Nov 15;104(10):2214-21.


Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma.

Doubrovina ES, Doubrovin MM, Vider E, Sisson RB, O'Reilly RJ, Dupont B, Vyas YM.

J Immunol. 2003 Dec 15;171(12):6891-9.


Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions.

Vyas YM, Mehta KM, Morgan M, Maniar H, Butros L, Jung S, Burkhardt JK, Dupont B.

J Immunol. 2001 Oct 15;167(8):4358-67.

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