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von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation.
Iwata K, Kawarabayashi K, Yoshizaki K, Tian T, Saito K, Sugimoto A, Kurogoushi R, Yamada A, Yamamoto A, Kudo Y, Ishimaru N, Fukumoto S, Iwamoto T. Iwata K, et al. J Cell Physiol. 2022 Mar;237(3):1964-1979. doi: 10.1002/jcp.30667. Epub 2021 Dec 26. J Cell Physiol. 2022. PMID: 34957547
Vwde-transfected M3H1 cells secreted VWDE protein into the culture medium and inhibited cell proliferation, whereas ameloblastic differentiation was promoted. ...Interestingly, the suppression of endogenous Vwde inhibited the expression of Ncad. Finally, we c …
Vwde-transfected M3H1 cells secreted VWDE protein into the culture medium and inhibited cell proliferation, whereas ameloblast …
von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration.
Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. Leigh ND, et al. Evol Dev. 2020 Jul;22(4):297-311. doi: 10.1111/ede.12332. Epub 2020 Mar 12. Evol Dev. 2020. PMID: 32163674 Free PMC article.
Further, vwde expression is tightly linked to the ability to regenerate appendages in Xenopus laevis. Functional experiments demonstrate a requirement for vwde in regeneration and indicate that Vwde is a potent growth factor in the blastema. ...
Further, vwde expression is tightly linked to the ability to regenerate appendages in Xenopus laevis. Functional experiments demonstr …
Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials.
Mostovenko E, Dahm MM, Schubauer-Berigan MK, Eye T, Erdely A, Young TL, Campen MJ, Ottens AK. Mostovenko E, et al. Part Fibre Toxicol. 2021 Oct 28;18(1):39. doi: 10.1186/s12989-021-00431-0. Part Fibre Toxicol. 2021. PMID: 34711247 Free PMC article.
ARHGAP21, ADAM15 and PLPP3 peptides suggest heightened cardiovasculature permeability and F13A1, FBN1 and VWDE peptides infer a pro-thrombotic state among High CNT/F workers. ...
ARHGAP21, ADAM15 and PLPP3 peptides suggest heightened cardiovasculature permeability and F13A1, FBN1 and VWDE peptides infer a pro-t …
Leukocyte methylomic imprints of exposure to the genocide against the Tutsi in Rwanda: a pilot epigenome-wide analysis.
Musanabaganwa C, Wani AH, Donglasan J, Fatumo S, Jansen S, Mutabaruka J, Rutembesa E, Uwineza A, Hermans EJ, Roozendaal B, Wildman DE, Mutesa L, Uddin M. Musanabaganwa C, et al. Epigenomics. 2022 Jan;14(1):11-25. doi: 10.2217/epi-2021-0310. Epub 2021 Dec 8. Epigenomics. 2022. PMID: 34875875 Free PMC article.
Conclusions:In utero genocide exposure was associated with CpGs in three of the 24 DMRs: BCOR, PRDM8 and VWDE, with higher DNA methylation in exposed versus unexposed offspring. Of note, BCOR and VWDE show significant correlation between brain and blood DNA methylat …
Conclusions:In utero genocide exposure was associated with CpGs in three of the 24 DMRs: BCOR, PRDM8 and VWDE, with higher DNA methyl …
A comprehensive analysis of copy number variation in a Turkish dementia cohort.
Dehghani N, Guven G, Kun-Rodrigues C, Gouveia C, Foster K, Hanagasi H, Lohmann E, Samanci B, Gurvit H, Bilgic B, Bras J, Guerreiro R. Dehghani N, et al. Hum Genomics. 2021 Jul 28;15(1):48. doi: 10.1186/s40246-021-00346-z. Hum Genomics. 2021. PMID: 34321086 Free PMC article.
Additionally, we also describe novel CNVs potentially associated with dementia, overlapping the genes AFG1L, SNX3, VWDE, and BC039545. CONCLUSIONS: Genotyping data from understudied populations can be utilized to identify copy number variation which may contribute to demen …
Additionally, we also describe novel CNVs potentially associated with dementia, overlapping the genes AFG1L, SNX3, VWDE, and BC039545 …
A Prognostic Model Based on Nine DNA Methylation-Driven Genes Predicts Overall Survival for Colorectal Cancer.
Feng Z, Liu Z, Peng K, Wu W. Feng Z, et al. Front Genet. 2022 Jan 21;12:779383. doi: 10.3389/fgene.2021.779383. eCollection 2021. Front Genet. 2022. PMID: 35126454 Free PMC article.
Based on the LASSO and Cox regression analyses, nine genes, i.e., LINC01555, GSTM1, HSPA1A, VWDE, MAGEA12, ARHGAP, PTPRD, ABHD12B and TMEM88, were selected for the development of a risk score model. ...
Based on the LASSO and Cox regression analyses, nine genes, i.e., LINC01555, GSTM1, HSPA1A, VWDE, MAGEA12, ARHGAP, PTPRD, ABHD12B and …
A genome-wide approach to link genotype to clinical outcome by utilizing next generation sequencing and gene chip data of 6,697 breast cancer patients.
Pongor L, Kormos M, Hatzis C, Pusztai L, Szabó A, Győrffy B. Pongor L, et al. Genome Med. 2015 Oct 16;7:104. doi: 10.1186/s13073-015-0228-1. Genome Med. 2015. PMID: 26474971 Free PMC article.
RESULTS: According to this approach, the top driver oncogenes having a mutation prevalence over 5 % included AKT1, TRANK1, TRAPPC10, RPGR, COL6A2, RAPGEF4, ATG2B, CNTRL, NAA38, OSBPL10, POTEF, SCLT1, SUN1, VWDE, MTUS2, and PIK3CA, and the top tumor suppressor genes include …
RESULTS: According to this approach, the top driver oncogenes having a mutation prevalence over 5 % included AKT1, TRANK1, TRAPPC10, RPGR, C …