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Items: 12

1.

A Rationally Designed Peptide Antagonist of the PD-1 Signaling Pathway as an Immunomodulatory Agent for Cancer Therapy.

Sasikumar PG, Ramachandra RK, Adurthi S, Dhudashiya AA, Vadlamani S, Vemula K, Vunnum S, Satyam LK, Samiulla DS, Subbarao K, Nair R, Shrimali R, Gowda N, Ramachandra M.

Mol Cancer Ther. 2019 Jun;18(6):1081-1091. doi: 10.1158/1535-7163.MCT-18-0737. Epub 2019 Apr 23.

PMID:
31015307
2.

Evaluation of effects of pH and ionic strength on colloidal stability of IgG solutions by PEG-induced liquid-liquid phase separation.

Thompson RW Jr, Latypov RF, Wang Y, Lomakin A, Meyer JA, Vunnum S, Benedek GB.

J Chem Phys. 2016 Nov 14;145(18):185101.

PMID:
27846698
3.

Modeling and robust pooling design of a preparative cation-exchange chromatography step for purification of monoclonal antibody monomer from aggregates.

Borg N, Brodsky Y, Moscariello J, Vunnum S, Vedantham G, Westerberg K, Nilsson B.

J Chromatogr A. 2014 Sep 12;1359:170-81. doi: 10.1016/j.chroma.2014.07.041. Epub 2014 Jul 21.

PMID:
25085821
4.

Quantitative evaluation of colloidal stability of antibody solutions using PEG-induced liquid-liquid phase separation.

Wang Y, Latypov RF, Lomakin A, Meyer JA, Kerwin BA, Vunnum S, Benedek GB.

Mol Pharm. 2014 May 5;11(5):1391-402. doi: 10.1021/mp400521b. Epub 2014 Apr 15.

PMID:
24679215
5.

Cation exchange surface-mediated denaturation of an aglycosylated immunoglobulin (IgG1).

Gillespie R, Nguyen T, Macneil S, Jones L, Crampton S, Vunnum S.

J Chromatogr A. 2012 Aug 17;1251:101-110. doi: 10.1016/j.chroma.2012.06.037. Epub 2012 Jun 20.

PMID:
22771262
6.

Cation exchange chromatography provides effective retrovirus clearance for antibody purification processes.

Connell-Crowley L, Nguyen T, Bach J, Chinniah S, Bashiri H, Gillespie R, Moscariello J, Hinckley P, Dehghani H, Vunnum S, Vedantham G.

Biotechnol Bioeng. 2012 Jan;109(1):157-65. doi: 10.1002/bit.23300. Epub 2011 Aug 23.

PMID:
21837666
7.

Crystallization and liquid-liquid phase separation of monoclonal antibodies and fc-fusion proteins: screening results.

Trilisky E, Gillespie R, Osslund TD, Vunnum S.

Biotechnol Prog. 2011 Jul;27(4):1054-67. doi: 10.1002/btpr.621. Epub 2011 Jun 8.

PMID:
21656920
8.

Photochemical degradation of citrate buffers leads to covalent acetonation of recombinant protein therapeutics.

Valliere-Douglass JF, Connell-Crowley L, Jensen R, Schnier PD, Trilisky E, Leith M, Follstad BD, Kerr J, Lewis N, Vunnum S, Treuheit MJ, Balland A, Wallace A.

Protein Sci. 2010 Nov;19(11):2152-63. doi: 10.1002/pro.495.

9.

Weak partitioning chromatography for anion exchange purification of monoclonal antibodies.

Kelley BD, Tobler SA, Brown P, Coffman JL, Godavarti R, Iskra T, Switzer M, Vunnum S.

Biotechnol Bioeng. 2008 Oct 15;101(3):553-66. doi: 10.1002/bit.21923.

PMID:
18727127
10.

IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys.

Bree A, Schlerman FJ, Wadanoli M, Tchistiakova L, Marquette K, Tan XY, Jacobson BA, Widom A, Cook TA, Wood N, Vunnum S, Krykbaev R, Xu X, Donaldson DD, Goldman SJ, Sypek J, Kasaian MT.

J Allergy Clin Immunol. 2007 May;119(5):1251-7. Epub 2007 Mar 26.

PMID:
17379289
11.

IMAC: nonlinear elution chromatography of proteins.

Vunnum S, Cramer S.

Biotechnol Bioeng. 1997 May 20;54(4):373-90.

PMID:
18634105
12.

Protected amino acids as novel low-molecular-weight displacers in cation-exchange displacement chromatography.

Kundu A, Vunnum S, Jayaraman G, Cramer SM.

Biotechnol Bioeng. 1995 Dec 5;48(5):452-60.

PMID:
18623509

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