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Items: 37

1.

Metal-free visible light photoredox enables generation of carbyne equivalents via phosphonium ylide C-H activation.

Das M, Vu MD, Zhang Q, Liu XW.

Chem Sci. 2018 Dec 4;10(6):1687-1691. doi: 10.1039/c8sc04195d. eCollection 2019 Feb 14.

2.

Recent advances in reagent-controlled stereoselective/stereospecific glycosylation.

Yao H, Vu MD, Liu XW.

Carbohydr Res. 2019 Feb 1;473:72-81. doi: 10.1016/j.carres.2018.10.006. Epub 2018 Oct 22. Review.

PMID:
30641292
3.

Direct Aldehyde Csp2 -H Functionalization through Visible-Light-Mediated Photoredox Catalysis.

Vu MD, Das M, Liu XW.

Chemistry. 2017 Nov 13;23(63):15899-15902. doi: 10.1002/chem.201704224. Epub 2017 Oct 23.

PMID:
29057525
4.

Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment.

Seckinger A, Delgado JA, Moser S, Moreno L, Neuber B, Grab A, Lipp S, Merino J, Prosper F, Emde M, Delon C, Latzko M, Gianotti R, Lüoend R, Murr R, Hosse RJ, Harnisch LJ, Bacac M, Fauti T, Klein C, Zabaleta A, Hillengass J, Cavalcanti-Adam EA, Ho AD, Hundemer M, San Miguel JF, Strein K, Umaña P, Hose D, Paiva B, Vu MD.

Cancer Cell. 2017 Mar 13;31(3):396-410. doi: 10.1016/j.ccell.2017.02.002. Epub 2017 Mar 2.

5.

N-Linked Glycosyl Auxiliary-Mediated Native Chemical Ligation on Aspartic Acid: Application towards N-Glycopeptide Synthesis.

Chai H, Le Mai Hoang K, Vu MD, Pasunooti K, Liu CF, Liu XW.

Angew Chem Int Ed Engl. 2016 Aug 22;55(35):10363-7. doi: 10.1002/anie.201605597. Epub 2016 Jul 22.

PMID:
27444333
6.

Correction: Decreasing NF-κB Expression Enhances Odontoblastic Differentiation and Collagen Expression in Dental Pulp Stem Cells Exposed to Inflammatory Cytokines.

Hozhabri NS, Benson MD, Vu MD, Patel RH, Martinez RM, Nakhaie FN, Kim HK, Varanasi VG.

PLoS One. 2015 Apr 29;10(4):e0127494. doi: 10.1371/journal.pone.0127494. eCollection 2015. No abstract available.

7.

Decreasing NF-κB expression enhances odontoblastic differentiation and collagen expression in dental pulp stem cells exposed to inflammatory cytokines.

Hozhabri NS, Benson MD, Vu MD, Patel RH, Martinez RM, Nakhaie FN, Kim HK, Varanasi VG.

PLoS One. 2015 Jan 28;10(1):e0113334. doi: 10.1371/journal.pone.0113334. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0127494.

8.

Scaffold hopping towards potent and selective JAK3 inhibitors: discovery of novel C-5 substituted pyrrolopyrazines.

de Vicente J, Lemoine R, Bartlett M, Hermann JC, Hekmat-Nejad M, Henningsen R, Jin S, Kuglstatter A, Li H, Lovey AJ, Menke J, Niu L, Patel V, Petersen A, Setti L, Shao A, Tivitmahaisoon P, Vu MD, Soth M.

Bioorg Med Chem Lett. 2014 Nov 1;24(21):4969-75. doi: 10.1016/j.bmcl.2014.09.031. Epub 2014 Sep 21.

PMID:
25262541
9.

Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors.

Jaime-Figueroa S, De Vicente J, Hermann J, Jahangir A, Jin S, Kuglstatter A, Lynch SM, Menke J, Niu L, Patel V, Shao A, Soth M, Vu MD, Yee C.

Bioorg Med Chem Lett. 2013 May 1;23(9):2522-6. doi: 10.1016/j.bmcl.2013.03.015. Epub 2013 Mar 14.

PMID:
23541670
10.

Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome.

Lynch SM, DeVicente J, Hermann JC, Jaime-Figueroa S, Jin S, Kuglstatter A, Li H, Lovey A, Menke J, Niu L, Patel V, Roy D, Soth M, Steiner S, Tivitmahaisoon P, Vu MD, Yee C.

Bioorg Med Chem Lett. 2013 May 1;23(9):2793-800. doi: 10.1016/j.bmcl.2013.02.012. Epub 2013 Feb 13.

PMID:
23540648
11.

HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity.

Nguyen-Hoai T, Kobelt D, Hohn O, Vu MD, Schlag PM, Dörken B, Norley S, Lipp M, Walther W, Pezzutto A, Westermann J.

Oncoimmunology. 2012 Dec 1;1(9):1537-1545.

12.

3-Amido pyrrolopyrazine JAK kinase inhibitors: development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models.

Soth M, Hermann JC, Yee C, Alam M, Barnett JW, Berry P, Browner MF, Frank K, Frauchiger S, Harris S, He Y, Hekmat-Nejad M, Hendricks T, Henningsen R, Hilgenkamp R, Ho H, Hoffman A, Hsu PY, Hu DQ, Itano A, Jaime-Figueroa S, Jahangir A, Jin S, Kuglstatter A, Kutach AK, Liao C, Lynch S, Menke J, Niu L, Patel V, Railkar A, Roy D, Shao A, Shaw D, Steiner S, Sun Y, Tan SL, Wang S, Vu MD.

J Med Chem. 2013 Jan 10;56(1):345-56. doi: 10.1021/jm301646k. Epub 2012 Dec 19.

PMID:
23214979
13.

CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC.

Nguyen-Hoai T, Hohn O, Vu MD, Baldenhofer G, Sayed Ahmed MS, Dörken B, Norley S, Lipp M, Pezzutto A, Westermann J.

Cancer Gene Ther. 2012 Dec;19(12):880-7. doi: 10.1038/cgt.2012.78. Epub 2012 Oct 26.

PMID:
23099886
14.

RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.

Xu D, Kim Y, Postelnek J, Vu MD, Hu DQ, Liao C, Bradshaw M, Hsu J, Zhang J, Pashine A, Srinivasan D, Woods J, Levin A, O'Mahony A, Owens TD, Lou Y, Hill RJ, Narula S, DeMartino J, Fine JS.

J Pharmacol Exp Ther. 2012 Apr;341(1):90-103. doi: 10.1124/jpet.111.187740. Epub 2012 Jan 6.

PMID:
22228807
15.

CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model.

Nguyen-Hoai T, Baldenhofer G, Sayed Ahmed MS, Pham-Duc M, Vu MD, Lipp M, Dörken B, Pezzutto A, Westermann J.

Cancer Gene Ther. 2012 Jan;19(1):69-76. doi: 10.1038/cgt.2011.69. Epub 2011 Oct 14.

PMID:
21997231
16.

Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice.

Degauque N, Mariat C, Kenny J, Zhang D, Gao W, Vu MD, Alexopoulos S, Oukka M, Umetsu DT, DeKruyff RH, Kuchroo V, Zheng XX, Strom TB.

J Clin Invest. 2008 Feb;118(2):735-41.

17.

Striking dichotomy of PD-L1 and PD-L2 pathways in regulating alloreactive CD4(+) and CD8(+) T cells in vivo.

Habicht A, Kewalaramani R, Vu MD, Demirci G, Blazar BR, Sayegh MH, Li XC.

Am J Transplant. 2007 Dec;7(12):2683-92. Epub 2007 Oct 9.

18.

OX40 controls functionally different T cell subsets and their resistance to depletion therapy.

Kroemer A, Xiao X, Vu MD, Gao W, Minamimura K, Chen M, Maki T, Li XC.

J Immunol. 2007 Oct 15;179(8):5584-91.

19.

OX40 costimulation turns off Foxp3+ Tregs.

Vu MD, Xiao X, Gao W, Degauque N, Chen M, Kroemer A, Killeen N, Ishii N, Li XC.

Blood. 2007 Oct 1;110(7):2501-10. Epub 2007 Jun 15.

20.

NK cells promote transplant tolerance by killing donor antigen-presenting cells.

Yu G, Xu X, Vu MD, Kilpatrick ED, Li XC.

J Exp Med. 2006 Aug 7;203(8):1851-8. Epub 2006 Jul 24.

21.

Critical, but conditional, role of OX40 in memory T cell-mediated rejection.

Vu MD, Clarkson MR, Yagita H, Turka LA, Sayegh MH, Li XC.

J Immunol. 2006 Feb 1;176(3):1394-401.

22.

Sirolimus-mediated prolongation of rat cardiac allograft survival is enhanced by beta1 integrin very late antigen-4 blockade.

Vu MD, Qi S, Sehgal SN, Chen H, Kennedy JD.

Transplant Proc. 2005 Jan-Feb;37(1):162-3.

PMID:
15808581
23.

Mycophenolate mofetil is compatible with CD28/CD154 costimulatory blockade in preventing transplant rejection.

Vu MD, Li Y, Strom TB, Li XC.

Transplantation. 2005 Mar 27;79(6):736. No abstract available.

PMID:
15785384
24.

Study of T-cell costimulatory blockade in vivo at a single-cell level.

Vu MD, Li XC.

Methods Mol Med. 2005;109:409-20.

PMID:
15585935
25.

The common gammac-cytokines and transplantation tolerance.

Vu MD, Li XC.

Arch Immunol Ther Exp (Warsz). 2004 Jul-Aug;52(4):267-73. Review.

PMID:
15467491
26.

Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejection.

Vu MD, Amanullah F, Li Y, Demirci G, Sayegh MH, Li XC.

J Immunol. 2004 Jul 1;173(1):214-21.

27.

Combination therapy of malononitrilamide FK778 with tacrolimus on cell proliferation assays and in rats receiving renal allografts.

Vu MD, Qi S, Wang X, Jiang W, Ma A, Xu D, Bekersky I, Fitzsimmons WE, Wu J, Chen H.

Transplantation. 2003 May 15;75(9):1455-9.

PMID:
12792496
28.

Synergistic effect of vincristine with tacrolimus or sirolimus in prevention of acute heart allograft rejection in the rat.

Jiang W, Jiang J, Xu D, Wang X, Qi S, Ouyang J, Ma A, Vu MD, Bilolo KK, Chen H.

Microsurgery. 2003;23(2):117-22.

PMID:
12740883
29.

Significant prolongation of renal allograft survival by delayed combination therapy of FK778 with tacrolimus in nonhuman primates.

Qi S, Zhu S, Xu D, Wang X, Ouyang J, Jiang W, Vu MD, Bilolo K, Ma A, Johnson S, Daloze P, Bekersky I, Fitzsimmons WE, Chen H.

Transplantation. 2003 Apr 27;75(8):1124-8.

PMID:
12717189
30.

Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy.

Tremblay J, Chen H, Peng J, Kunes J, Vu MD, Der Sarkissian S, deBlois D, Bolton AE, Gaboury L, Marshansky V, Gouadon E, Hamet P.

Transplantation. 2002 Nov 27;74(10):1425-33.

PMID:
12451244
31.

Restoration of fertility in oophorectomized rats after tubo-ovarian transplantation.

Wang X, Bilolo KK, Qi S, Xu D, Jiang W, Vu MD, Chen H.

Microsurgery. 2002;22(1):30-3.

PMID:
11891873
32.

Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells.

Marshansky V, Wang X, Bertrand R, Luo H, Duguid W, Chinnadurai G, Kanaan N, Vu MD, Wu J.

J Immunol. 2001 Mar 1;166(5):3130-42.

33.

Compromised kidney graft rejection response in Vervet monkeys after withdrawal of immunosuppressants tacrolimus and sirolimus.

Chen H, Peng J, Luo H, Loubeau M, Wan X, Xu D, Qi S, Vu MD, Daloze P, Fitzsimmons WE, Bekersky I, Peets J, Sehgal SN, Wu J.

Transplantation. 2000 Apr 27;69(8):1555-61.

PMID:
10836361
34.

Effect of tacrolimus (FK506) and sirolimus (rapamycin) mono- and combination therapy in prolongation of renal allograft survival in the monkey.

Qi S, Xu D, Peng J, Vu MD, Wu J, Bekersky I, Fitzsimmons WE, Peets J, Sehgal S, Daloze P, Chen H.

Transplantation. 2000 Apr 15;69(7):1275-83.

PMID:
10798741
35.

Improved techniques for kidney transplantation in the monkey.

Qi S, Peng J, Xu D, Vu MD, Liu D, Chen H.

Microsurgery. 1999;19(7):335-7.

PMID:
10586199
36.
37.

Tacrolimus (FK506) and sirolimus (rapamycin) in combination are not antagonistic but produce extended graft survival in cardiac transplantation in the rat.

Vu MD, Qi S, Xu D, Wu J, Fitzsimmons WE, Sehgal SN, Dumont L, Busque S, Daloze P, Chen H.

Transplantation. 1997 Dec 27;64(12):1853-6.

PMID:
9422432

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