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Items: 1 to 50 of 99

1.

Classification of substandard factors in perinatal care: development and multidisciplinary inter-rater agreement of the Groningen-system.

van Diem MT, Timmer A, Gordijn SJ, Bergman KA, Korteweg FJ, Ravise J, Vreugdenhil E, Erwich JJ.

BMC Pregnancy Childbirth. 2015 Sep 11;15:215. doi: 10.1186/s12884-015-0638-5.

2.

Stress, glucocorticoid receptors, and adult neurogenesis: a balance between excitation and inhibition?

Saaltink DJ, Vreugdenhil E.

Cell Mol Life Sci. 2014 Jul;71(13):2499-515. doi: 10.1007/s00018-014-1568-5. Epub 2014 Feb 13. Review.

3.

β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.

Truong HH, Xiong J, Ghotra VP, Nirmala E, Haazen L, Le Dévédec SE, Balcioğlu HE, He S, Snaar-Jagalska BE, Vreugdenhil E, Meerman JH, van de Water B, Danen EH.

Sci Signal. 2014 Feb 11;7(312):ra15. doi: 10.1126/scisignal.2004751.

PMID:
24518294
4.

Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.

Verissimo CS, Elands R, Cheng S, Saaltink DJ, ter Horst JP, Alme MN, Pont C, van de Water B, Håvik B, Fitzsimons CP, Vreugdenhil E.

PLoS One. 2013 Sep 26;8(9):e75752. doi: 10.1371/journal.pone.0075752. eCollection 2013.

5.

Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior.

Fitzsimons CP, van Hooijdonk LW, Schouten M, Zalachoras I, Brinks V, Zheng T, Schouten TG, Saaltink DJ, Dijkmans T, Steindler DA, Verhaagen J, Verbeek FJ, Lucassen PJ, de Kloet ER, Meijer OC, Karst H, Joels M, Oitzl MS, Vreugdenhil E.

Mol Psychiatry. 2013 Sep;18(9):993-1005. doi: 10.1038/mp.2012.123. Epub 2012 Aug 28.

PMID:
22925833
6.

Doublecortin and doublecortin-like are expressed in overlapping and non-overlapping neuronal cell population: implications for neurogenesis.

Saaltink DJ, Håvik B, Verissimo CS, Lucassen PJ, Vreugdenhil E.

J Comp Neurol. 2012 Sep 1;520(13):2805-23. doi: 10.1002/cne.23144.

PMID:
22605579
7.

Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells.

Verissimo CS, Cheng S, Puigvert JC, Qin Y, Vroon A, van Deutekom J, Price LS, Danen EH, van de Water B, Fitzsimons CP, Vreugdenhil E.

J Pharmacol Exp Ther. 2012 Jul;342(1):119-30. doi: 10.1124/jpet.111.188813. Epub 2012 Apr 6.

8.

Leptin administration restores the fasting-induced increase of hepatic type 3 deiodinase expression in mice.

Boelen A, van Beeren M, Vos X, Surovtseva O, Belegri E, Saaltink DJ, Vreugdenhil E, Kalsbeek A, Kwakkel J, Fliers E.

Thyroid. 2012 Feb;22(2):192-9. doi: 10.1089/thy.2011.0289. Epub 2011 Dec 16.

PMID:
22175243
9.

Neuroblastoma therapy: what is in the pipeline?

Verissimo CS, Molenaar JJ, Fitzsimons CP, Vreugdenhil E.

Endocr Relat Cancer. 2011 Nov 14;18(6):R213-31. doi: 10.1530/ERC-11-0251. Print 2011 Dec. Review.

PMID:
21971288
10.

ERK-regulated double cortin-like kinase (DCLK)-short phosphorylation and nuclear translocation stimulate POMC gene expression in endocrine melanotrope cells.

Kuribara M, Jenks BG, Dijkmans TF, de Gouw D, Ouwens DT, Roubos EW, Vreugdenhil E, Scheenen WJ.

Endocrinology. 2011 Jun;152(6):2321-9. doi: 10.1210/en.2011-0067. Epub 2011 Mar 29.

PMID:
21447633
11.

Hippocampal CARP over-expression solidifies consolidation of contextual fear memories.

Schenk GJ, Vreugdenhil E, Hubens CJ, Veldhuisen B, de Kloet ER, Oitzl MS.

Physiol Behav. 2011 Mar 1;102(3-4):323-31. doi: 10.1016/j.physbeh.2010.11.024. Epub 2010 Dec 2.

PMID:
21130104
12.

Over-expression of δC-DCLK-short in mouse brain results in a more anxious behavioral phenotype.

Schenk GJ, Veldhuisen B, Wedemeier O, McGown CC, Schouten TG, Oitzl M, de Kloet ER, Vreugdenhil E.

Physiol Behav. 2010 Nov 2;101(4):541-8. doi: 10.1016/j.physbeh.2010.08.002. Epub 2010 Aug 10.

PMID:
20705078
13.

Over-expression of the DCLK gene transcript CARP decreases CA3/CA1 network excitability.

Schenk GJ, Werkman T, Wadman W, Veldhuisen B, Dijkmans TF, Blaas E, Kegel L, de Kloet ER, Vreugdenhil E.

Brain Res. 2010 Sep 17;1352:21-34. doi: 10.1016/j.brainres.2010.07.068. Epub 2010 Jul 24.

PMID:
20659433
14.

An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector.

de Backer MW, Fitzsimons CP, Brans MA, Luijendijk MC, Garner KM, Vreugdenhil E, Adan RA.

BMC Neurosci. 2010 Jul 13;11:81. doi: 10.1186/1471-2202-11-81.

15.

Acute pain increases phosphorylation of DCLK-long in the Edinger-Westphal nucleus but not in the hypothalamic paraventricular nucleus of the rat.

Rouwette TP, Kozicz T, Olde Loohuis NF, Gaszner B, Vreugdenhil E, Scheffer GJ, Roubos EW, Vissers KC, Scheenen WJ.

J Pain. 2010 Oct;11(10):930-40. doi: 10.1016/j.jpain.2009.12.017. Epub 2010 Apr 24.

PMID:
20418180
16.

The doublecortin gene family and disorders of neuronal structure.

Dijkmans TF, van Hooijdonk LW, Fitzsimons CP, Vreugdenhil E.

Cent Nerv Syst Agents Med Chem. 2010 Mar;10(1):32-46. Review.

PMID:
20236041
17.

Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.

Verissimo CS, Molenaar JJ, Meerman J, Puigvert JC, Lamers F, Koster J, Danen EH, van de Water B, Versteeg R, Fitzsimons CP, Vreugdenhil E.

Endocr Relat Cancer. 2010 Apr 21;17(2):399-414. doi: 10.1677/ERC-09-0301. Print 2010 Jun.

PMID:
20228126
18.

Fine-tuning the brain: MicroRNAs.

Vreugdenhil E, Berezikov E.

Front Neuroendocrinol. 2010 Apr;31(2):128-33. doi: 10.1016/j.yfrne.2009.08.001. Epub 2009 Aug 13. Review.

PMID:
19683017
19.

Doublecortin-like (DCL) expression in focal cortical dysplasia and cortical tubers.

Boer K, Lucassen PJ, Spliet WG, Vreugdenhil E, van Rijen PC, Troost D, Jansen FE, Aronica E.

Epilepsia. 2009 Dec;50(12):2629-37. doi: 10.1111/j.1528-1167.2009.02191.x. Epub 2009 Jul 2.

20.

Glucocorticoid signaling and stress-related limbic susceptibility pathway: about receptors, transcription machinery and microRNA.

de Kloet ER, Fitzsimons CP, Datson NA, Meijer OC, Vreugdenhil E.

Brain Res. 2009 Oct 13;1293:129-41. doi: 10.1016/j.brainres.2009.03.039. Epub 2009 Mar 28.

PMID:
19332027
21.

Antiglucocorticoids, neurogenesis and depression.

Fitzsimons CP, van Hooijdonk LW, Morrow JA, Peeters BW, Hamilton N, Craighead M, Vreugdenhil E.

Mini Rev Med Chem. 2009 Feb;9(2):249-64. Review.

PMID:
19200029
22.

Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression.

van Hooijdonk LW, Ichwan M, Dijkmans TF, Schouten TG, de Backer MW, Adan RA, Verbeek FJ, Vreugdenhil E, Fitzsimons CP.

BMC Neurosci. 2009 Jan 13;10:2. doi: 10.1186/1471-2202-10-2.

23.

MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain.

Vreugdenhil E, Verissimo CS, Mariman R, Kamphorst JT, Barbosa JS, Zweers T, Champagne DL, Schouten T, Meijer OC, de Kloet ER, Fitzsimons CP.

Endocrinology. 2009 May;150(5):2220-8. doi: 10.1210/en.2008-1335. Epub 2009 Jan 8.

PMID:
19131573
24.

Identification of new Nerve Growth Factor-responsive immediate-early genes.

Dijkmans TF, van Hooijdonk LW, Schouten TG, Kamphorst JT, Fitzsimons CP, Vreugdenhil E.

Brain Res. 2009 Jan 16;1249:19-33. doi: 10.1016/j.brainres.2008.10.050. Epub 2008 Oct 31.

PMID:
19013137
25.

Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms.

't Hoen PA, Ariyurek Y, Thygesen HH, Vreugdenhil E, Vossen RH, de Menezes RX, Boer JM, van Ommen GJ, den Dunnen JT.

Nucleic Acids Res. 2008 Dec;36(21):e141. doi: 10.1093/nar/gkn705. Epub 2008 Oct 15.

26.

Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain.

van der Laan S, Sarabdjitsingh RA, Van Batenburg MF, Lachize SB, Li H, Dijkmans TF, Vreugdenhil E, de Kloet ER, Meijer OC.

J Neurochem. 2008 Sep;106(6):2515-23. doi: 10.1111/j.1471-4159.2008.05575.x. Epub 2008 Jul 15.

27.

Temporal and functional dynamics of the transcriptome during nerve growth factor-induced differentiation.

Dijkmans TF, van Hooijdonk LW, Schouten TG, Kamphorst JT, Vellinga AC, Meerman JH, Fitzsimons CP, de Kloet ER, Vreugdenhil E.

J Neurochem. 2008 Jun 1;105(6):2388-403. doi: 10.1111/j.1471-4159.2008.05338.x.

28.

Can subtle changes in gene expression be consistently detected with different microarray platforms?

Pedotti P, 't Hoen PA, Vreugdenhil E, Schenk GJ, Vossen RH, Ariyurek Y, de Hollander M, Kuiper R, van Ommen GJ, den Dunnen JT, Boer JM, de Menezes RX.

BMC Genomics. 2008 Mar 10;9:124. doi: 10.1186/1471-2164-9-124.

29.

Doublecortin (DCX) and doublecortin-like (DCL) are differentially expressed in the early but not late stages of murine neocortical development.

Boekhoorn K, Sarabdjitsingh A, Kommerie H, de Punder K, Schouten T, Lucassen PJ, Vreugdenhil E.

J Comp Neurol. 2008 Apr 1;507(4):1639-52. doi: 10.1002/cne.21646.

PMID:
18231966
30.

A potential role for calcium / calmodulin-dependent protein kinase-related peptide in neuronal apoptosis: in vivo and in vitro evidence.

Schenk GJ, Engels B, Zhang YP, Fitzsimons CP, Schouten T, Kruidering M, de Kloet ER, Vreugdenhil E.

Eur J Neurosci. 2007 Dec;26(12):3411-20. Epub 2007 Dec 4.

PMID:
18052980
31.

Nuclear receptor coregulators differentially modulate induction and glucocorticoid receptor-mediated repression of the corticotropin-releasing hormone gene.

van der Laan S, Lachize SB, Vreugdenhil E, de Kloet ER, Meijer OC.

Endocrinology. 2008 Feb;149(2):725-32. Epub 2007 Nov 15.

PMID:
18006628
32.

The microtubule-associated protein doublecortin-like regulates the transport of the glucocorticoid receptor in neuronal progenitor cells.

Fitzsimons CP, Ahmed S, Wittevrongel CF, Schouten TG, Dijkmans TF, Scheenen WJ, Schaaf MJ, de Kloet ER, Vreugdenhil E.

Mol Endocrinol. 2008 Feb;22(2):248-62. Epub 2007 Nov 1.

33.

Dynamic changes of proteases and protease inhibitors revealed by microarray analysis in CA3 and entorhinal cortex during epileptogenesis in the rat.

Gorter JA, Van Vliet EA, Rauwerda H, Breit T, Stad R, van Schaik L, Vreugdenhil E, Redeker S, Hendriksen E, Aronica E, Lopes da Silva FH, Wadman WJ.

Epilepsia. 2007;48 Suppl 5:53-64. Erratum in: Epilepsia. 2007 Dec;48(12):2379.

34.

Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability.

Vreugdenhil E, Kolk SM, Boekhoorn K, Fitzsimons CP, Schaaf M, Schouten T, Sarabdjitsingh A, Sibug R, Lucassen PJ.

Eur J Neurosci. 2007 Feb;25(3):635-48.

PMID:
17313568
35.

A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness.

DeRijk RH, Wüst S, Meijer OC, Zennaro MC, Federenko IS, Hellhammer DH, Giacchetti G, Vreugdenhil E, Zitman FG, de Kloet ER.

J Clin Endocrinol Metab. 2006 Dec;91(12):5083-9. Epub 2006 Oct 3.

PMID:
17018659
36.

Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet.

Hoekstra M, Stitzinger M, van Wanrooij EJ, Michon IN, Kruijt JK, Kamphorst J, Van Eck M, Vreugdenhil E, Van Berkel TJ, Kuiper J.

J Lipid Res. 2006 Oct;47(10):2198-207. Epub 2006 Aug 2.

37.

The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates.

Feldker DE, Morsink MC, Veenema AH, Datson NA, Proutski V, Lathouwers D, de Kloet ER, Vreugdenhil E.

Brain Res. 2006 May 17;1089(1):10-20. Epub 2006 May 5.

PMID:
16678802
38.

Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain.

van der Laan S, Lachize SB, Schouten TG, Vreugdenhil E, de Kloet ER, Meijer OC.

Brain Res. 2005 Oct 19;1059(2):113-21. Epub 2005 Oct 5.

PMID:
16212947
39.

Functional differences between two DCLK splice variants.

Engels BM, Schouten TG, van Dullemen J, Gosens I, Vreugdenhil E.

Brain Res Mol Brain Res. 2004 Jan 5;120(2):103-14.

PMID:
14741399
40.

GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: technical and biological implications.

Feldker DE, Datson NA, Veenema AH, Proutski V, Lathouwers D, De Kloet ER, Vreugdenhil E.

J Neurosci Res. 2003 Dec 1;74(5):701-16.

PMID:
14635221
41.

Very low levels of the glucocorticoid receptor beta isoform in the human hippocampus as shown by Taqman RT-PCR and immunocytochemistry.

DeRijk RH, Schaaf M, Stam FJ, de Jong IE, Swaab DF, Ravid R, Vreugdenhil E, Cidlowski JA, de Kloet ER, Lucassen PJ.

Brain Res Mol Brain Res. 2003 Aug 19;116(1-2):17-26.

PMID:
12941457
42.

Gene expression changes in single dentate granule neurons after adrenalectomy of rats.

Qin Y, Nair S, Karst H, Vreugdenhil E, Datson N, Joëls M.

Brain Res Mol Brain Res. 2003 Mar 17;111(1-2):17-23.

PMID:
12654501
43.

Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice.

Feldker DE, Datson NA, Veenema AH, Meulmeester E, de Kloet ER, Vreugdenhil E.

Eur J Neurosci. 2003 Jan;17(2):379-87.

PMID:
12542675
44.

Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis. Serial Analysis of Gene Expression.

Evans SJ, Datson NA, Kabbaj M, Thompson RC, Vreugdenhil E, De Kloet ER, Watson SJ, Akil H.

Eur J Neurosci. 2002 Aug;16(3):409-13. Review.

45.

Identification of differentially regulated genes in mildly hyperlipidemic ApoE3-Leiden mice by use of serial analysis of gene expression.

Kreeft AJ, Moen CJ, Hofker MH, Frants RR, Vreugdenhil E, Gijbels MJ, Havekes LM, Datson NA.

Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):1984-90.

PMID:
11742874
46.

Altered hippocampal gene expression prior to the onset of spontaneous seizures in the rat post-status epilepticus model.

Hendriksen H, Datson NA, Ghijsen WE, van Vliet EA, da Silva FH, Gorter JA, Vreugdenhil E.

Eur J Neurosci. 2001 Nov;14(9):1475-84.

PMID:
11722609
47.

A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis.

Derijk RH, Schaaf MJ, Turner G, Datson NA, Vreugdenhil E, Cidlowski J, de Kloet ER, Emery P, Sternberg EM, Detera-Wadleigh SD.

J Rheumatol. 2001 Nov;28(11):2383-8.

PMID:
11708406
48.

Genetic dissection of corticosterone receptor function in the rat hippocampus.

Vreugdenhil E, de Kloet ER, Schaaf M, Datson NA.

Eur Neuropsychopharmacol. 2001 Dec;11(6):423-30. Review.

PMID:
11704419
49.

Multiple transcripts generated by the DCAMKL gene are expressed in the rat hippocampus.

Vreugdenhil E, Engels B, Middelburg R, van Koningsbruggen S, Knol J, Veldhuisen B, de Kloet ER.

Brain Res Mol Brain Res. 2001 Oct 19;94(1-2):67-74.

PMID:
11597766
50.

Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats.

Schaaf MJ, Workel JO, Lesscher HM, Vreugdenhil E, Oitzl MS, de Kloet ER.

Brain Res. 2001 Oct 12;915(2):227-33.

PMID:
11595212

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