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Items: 22

1.

Impact of LEDGIN treatment during virus production on residual HIV-1 transcription.

Vansant G, Vranckx LS, Zurnic I, Van Looveren D, Van de Velde P, Nobles C, Gijsbers R, Christ F, Debyser Z.

Retrovirology. 2019 Apr 2;16(1):8. doi: 10.1186/s12977-019-0472-3.

2.

Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection.

Lampi Y, Van Looveren D, Vranckx LS, Thiry I, Bornschein S, Debyser Z, Gijsbers R.

Sci Rep. 2019 Feb 20;9(1):2389. doi: 10.1038/s41598-019-38718-0.

3.

Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent.

Lévy C, Amirache F, Girard-Gagnepain A, Frecha C, Roman-Rodríguez FJ, Bernadin O, Costa C, Nègre D, Gutierrez-Guerrero A, Vranckx LS, Clerc I, Taylor N, Thielecke L, Cornils K, Bueren JA, Rio P, Gijsbers R, Cosset FL, Verhoeyen E.

Blood Adv. 2017 Oct 24;1(23):2088-2104. doi: 10.1182/bloodadvances.2017007773. eCollection 2017 Oct 24.

4.

Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor.

Roymans D, Alnajjar SS, Battles MB, Sitthicharoenchai P, Furmanova-Hollenstein P, Rigaux P, Berg JVD, Kwanten L, Ginderen MV, Verheyen N, Vranckx L, Jaensch S, Arnoult E, Voorzaat R, Gallup JM, Larios-Mora A, Crabbe M, Huntjens D, Raboisson P, Langedijk JP, Ackermann MR, McLellan JS, Vendeville S, Koul A.

Nat Commun. 2017 Aug 1;8(1):167. doi: 10.1038/s41467-017-00170-x.

5.

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy.

El Ashkar S, Van Looveren D, Schenk F, Vranckx LS, Demeulemeester J, De Rijck J, Debyser Z, Modlich U, Gijsbers R.

Mol Ther Nucleic Acids. 2017 Jun 16;7:231-245. doi: 10.1016/j.omtn.2017.04.002. Epub 2017 Apr 12.

6.

Insight into HIV-2 latency may disclose strategies for a cure for HIV-1 infection.

Saleh S, Vranckx L, Gijsbers R, Christ F, Debyser Z.

J Virus Erad. 2017 Jan 1;3(1):7-14.

7.

Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.

Vranckx LS, Demeulemeester J, Debyser Z, Gijsbers R.

PLoS One. 2016 Oct 27;11(10):e0164167. doi: 10.1371/journal.pone.0164167. eCollection 2016.

8.

LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV.

Vranckx LS, Demeulemeester J, Saleh S, Boll A, Vansant G, Schrijvers R, Weydert C, Battivelli E, Verdin E, Cereseto A, Christ F, Gijsbers R, Debyser Z.

EBioMedicine. 2016 Jun;8:248-264. doi: 10.1016/j.ebiom.2016.04.039. Epub 2016 May 13.

9.

In vitro culture conditions affecting minimal inhibitory concentration of bedaquiline against M. tuberculosis.

Lounis N, Vranckx L, Gevers T, Kaniga K, Andries K.

Med Mal Infect. 2016 Jun;46(4):220-5. doi: 10.1016/j.medmal.2016.04.007.

PMID:
27210281
10.

Comparative Analysis of HIV-1 and Murine Leukemia Virus Three-Dimensional Nuclear Distributions.

Quercioli V, Di Primio C, Casini A, Mulder LCF, Vranckx LS, Borrenberghs D, Gijsbers R, Debyser Z, Cereseto A.

J Virol. 2016 Apr 29;90(10):5205-5209. doi: 10.1128/JVI.03188-15. Print 2016 May 15.

11.

Molecular mechanism of respiratory syncytial virus fusion inhibitors.

Battles MB, Langedijk JP, Furmanova-Hollenstein P, Chaiwatpongsakorn S, Costello HM, Kwanten L, Vranckx L, Vink P, Jaensch S, Jonckers TH, Koul A, Arnoult E, Peeples ME, Roymans D, McLellan JS.

Nat Chem Biol. 2016 Feb;12(2):87-93. doi: 10.1038/nchembio.1982. Epub 2015 Dec 7.

12.

Acquired resistance of Mycobacterium tuberculosis to bedaquiline.

Andries K, Villellas C, Coeck N, Thys K, Gevers T, Vranckx L, Lounis N, de Jong BC, Koul A.

PLoS One. 2014 Jul 10;9(7):e102135. doi: 10.1371/journal.pone.0102135. eCollection 2014.

13.

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism.

Koul A, Vranckx L, Dhar N, Göhlmann HW, Özdemir E, Neefs JM, Schulz M, Lu P, Mørtz E, McKinney JD, Andries K, Bald D.

Nat Commun. 2014 Feb 26;5:3369. doi: 10.1038/ncomms4369.

14.

Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.

Balemans W, Vranckx L, Lounis N, Pop O, Guillemont J, Vergauwen K, Mol S, Gilissen R, Motte M, Lançois D, De Bolle M, Bonroy K, Lill H, Andries K, Bald D, Koul A.

Antimicrob Agents Chemother. 2012 Aug;56(8):4131-9. doi: 10.1128/AAC.00273-12. Epub 2012 May 21.

15.

ATP synthase inhibition of Mycobacterium avium is not bactericidal.

Lounis N, Gevers T, Van den Berg J, Vranckx L, Andries K.

Antimicrob Agents Chemother. 2009 Nov;53(11):4927-9. doi: 10.1128/AAC.00689-09. Epub 2009 Sep 8.

16.

Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis.

Koul A, Vranckx L, Dendouga N, Balemans W, Van den Wyngaert I, Vergauwen K, Göhlmann HW, Willebrords R, Poncelet A, Guillemont J, Bald D, Andries K.

J Biol Chem. 2008 Sep 12;283(37):25273-80. doi: 10.1074/jbc.M803899200. Epub 2008 Jul 14.

17.

Legionella pneumophila exhibits plasminogen activator activity.

Vranckx L, De Buck E, Anné J, Lammertyn E.

Microbiology. 2007 Nov;153(Pt 11):3757-65.

PMID:
17975084
18.

Diarylquinolines target subunit c of mycobacterial ATP synthase.

Koul A, Dendouga N, Vergauwen K, Molenberghs B, Vranckx L, Willebrords R, Ristic Z, Lill H, Dorange I, Guillemont J, Bald D, Andries K.

Nat Chem Biol. 2007 Jun;3(6):323-4. Epub 2007 May 13.

PMID:
17496888
19.

The twin-arginine translocation pathway is necessary for correct membrane insertion of the Rieske Fe/S protein in Legionella pneumophila.

De Buck E, Vranckx L, Meyen E, Maes L, Vandersmissen L, Anné J, Lammertyn E.

FEBS Lett. 2007 Jan 23;581(2):259-64. Epub 2006 Dec 18.

20.

The type II signal peptidase of Legionella pneumophila.

Geukens N, De Buck E, Meyen E, Maes L, Vranckx L, Van Mellaert L, Anné J, Lammertyn E.

Res Microbiol. 2006 Nov;157(9):836-41. Epub 2006 Jul 12.

PMID:
17005379
21.

Antifungal susceptibility testing of yeasts: evaluation of technical variables for test automation.

Odds FC, Vranckx L, Woestenborghs F.

Antimicrob Agents Chemother. 1995 Sep;39(9):2051-60.

22.

Oxygen as limiting nutrient for growth of Cryptococcus neoformans.

Odds FC, De Backer T, Dams G, Vranckx L, Woestenborghs F.

J Clin Microbiol. 1995 Apr;33(4):995-7.

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