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Items: 19


Machine Learning Predicts the Yeast Metabolome from the Quantitative Proteome of Kinase Knockouts.

Zelezniak A, Vowinckel J, Capuano F, Messner CB, Demichev V, Polowsky N, Mülleder M, Kamrad S, Klaus B, Keller MA, Ralser M.

Cell Syst. 2018 Sep 26;7(3):269-283.e6. doi: 10.1016/j.cels.2018.08.001. Epub 2018 Sep 5.


Proteotype profiling unmasks a viral signalling network essential for poxvirus assembly and transcriptional competence.

Novy K, Kilcher S, Omasits U, Bleck CKE, Beerli C, Vowinckel J, Martin CK, Syedbasha M, Maiolica A, White I, Mercer J, Wollscheid B.

Nat Microbiol. 2018 May;3(5):588-599. doi: 10.1038/s41564-018-0142-6. Epub 2018 Apr 9.


Cost-effective generation of precise label-free quantitative proteomes in high-throughput by microLC and data-independent acquisition.

Vowinckel J, Zelezniak A, Bruderer R, Mülleder M, Reiter L, Ralser M.

Sci Rep. 2018 Mar 12;8(1):4346. doi: 10.1038/s41598-018-22610-4.


Variable repeats in the eukaryotic polyubiquitin gene ubi4 modulate proteostasis and stress survival.

Gemayel R, Yang Y, Dzialo MC, Kominek J, Vowinckel J, Saels V, Van Huffel L, van der Zande E, Ralser M, Steensels J, Voordeckers K, Verstrepen KJ.

Nat Commun. 2017 Aug 30;8(1):397. doi: 10.1038/s41467-017-00533-4.


The metabolic background is a global player in Saccharomyces gene expression epistasis.

Alam MT, Zelezniak A, Mülleder M, Shliaha P, Schwarz R, Capuano F, Vowinckel J, Radmanesfahar E, Krüger A, Calvani E, Michel S, Börno S, Christen S, Patil KR, Timmermann B, Lilley KS, Ralser M.

Nat Microbiol. 2016 Feb 1;1:15030. doi: 10.1038/nmicrobiol.2015.30.


Cell-to-cell heterogeneity emerges as consequence of metabolic cooperation in a synthetic yeast community.

Campbell K, Vowinckel J, Ralser M.

Biotechnol J. 2016 Sep;11(9):1169-78. doi: 10.1002/biot.201500301. Epub 2016 Jul 5.


Analysis of Drosophila melanogaster proteome dynamics during embryonic development by a combination of label-free proteomics approaches.

Fabre B, Korona D, Groen A, Vowinckel J, Gatto L, Deery MJ, Ralser M, Russell S, Lilley KS.

Proteomics. 2016 Aug;16(15-16):2068-80. doi: 10.1002/pmic.201500482. Epub 2016 May 10.


Methionine Metabolism Alters Oxidative Stress Resistance via the Pentose Phosphate Pathway.

Campbell K, Vowinckel J, Keller MA, Ralser M.

Antioxid Redox Signal. 2016 Apr 1;24(10):543-7. doi: 10.1089/ars.2015.6516. Epub 2016 Mar 15.


Self-establishing communities enable cooperative metabolite exchange in a eukaryote.

Campbell K, Vowinckel J, Mülleder M, Malmsheimer S, Lawrence N, Calvani E, Miller-Fleming L, Alam MT, Christen S, Keller MA, Ralser M.

Elife. 2015 Oct 26;4. pii: e09943. doi: 10.7554/eLife.09943.


MitoLoc: A method for the simultaneous quantification of mitochondrial network morphology and membrane potential in single cells.

Vowinckel J, Hartl J, Butler R, Ralser M.

Mitochondrion. 2015 Sep;24:77-86. doi: 10.1016/j.mito.2015.07.001. Epub 2015 Jul 13.


Using the canary genome to decipher the evolution of hormone-sensitive gene regulation in seasonal singing birds.

Frankl-Vilches C, Kuhl H, Werber M, Klages S, Kerick M, Bakker A, de Oliveira EH, Reusch C, Capuano F, Vowinckel J, Leitner S, Ralser M, Timmermann B, Gahr M.

Genome Biol. 2015 Jan 29;16:19. doi: 10.1186/s13059-014-0578-9.


Mitochondria in ageing: there is metabolism beyond the ROS.

Breitenbach M, Rinnerthaler M, Hartl J, Stincone A, Vowinckel J, Breitenbach-Koller H, Ralser M.

FEMS Yeast Res. 2014 Feb;14(1):198-212. doi: 10.1111/1567-1364.12134. Epub 2014 Jan 16. Review.


Tpo1-mediated spermine and spermidine export controls cell cycle delay and times antioxidant protein expression during the oxidative stress response.

Krüger A, Vowinckel J, Mülleder M, Grote P, Capuano F, Bluemlein K, Ralser M.

EMBO Rep. 2013 Dec;14(12):1113-9. doi: 10.1038/embor.2013.165. Epub 2013 Oct 18.


The beauty of being (label)-free: sample preparation methods for SWATH-MS and next-generation targeted proteomics.

Vowinckel J, Capuano F, Campbell K, Deery MJ, Lilley KS, Ralser M.

Version 2. F1000Res. 2013 Dec 13 [revised 2014 Jan 1];2:272. doi: 10.12688/f1000research.2-272.v2. eCollection 2013.


Histaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signaling.

Vowinckel J, Stahlberg S, Paulmann N, Bluemlein K, Grohmann M, Ralser M, Walther DJ.

FEBS Lett. 2012 Nov 2;586(21):3819-24. doi: 10.1016/j.febslet.2012.09.027. Epub 2012 Sep 26.


Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases.

Walther DJ, Stahlberg S, Vowinckel J.

FEBS J. 2011 Dec;278(24):4740-55. doi: 10.1111/j.1742-4658.2011.08347.x. Epub 2011 Nov 21. Review.


Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation.

Paulmann N, Grohmann M, Voigt JP, Bert B, Vowinckel J, Bader M, Skelin M, Jevsek M, Fink H, Rupnik M, Walther DJ.

PLoS Biol. 2009 Oct;7(10):e1000229. doi: 10.1371/journal.pbio.1000229. Epub 2009 Oct 27.


A mammalianized synthetic nitroreductase gene for high-level expression.

Grohmann M, Paulmann N, Fleischhauer S, Vowinckel J, Priller J, Walther DJ.

BMC Cancer. 2009 Aug 27;9:301. doi: 10.1186/1471-2407-9-301.


Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release.

Walther DJ, Peter JU, Winter S, Höltje M, Paulmann N, Grohmann M, Vowinckel J, Alamo-Bethencourt V, Wilhelm CS, Ahnert-Hilger G, Bader M.

Cell. 2003 Dec 26;115(7):851-62.

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