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Items: 1 to 50 of 53

1.

PI3K/AKT pathway genetic alterations and dysregulation of expression in bladder cancer.

Kachrilas S, Dellis A, Papatsoris A, Avgeris S, Anastasiou D, Gavriil A, Horti M, Tseleni Balafouta S, Livadas K, Stravopodis DJ, Alivizatos G, Voutsinas GE, Deliveliotis C.

J BUON. 2019 Jan-Feb;24(1):329-337.

2.

Revisiting Histone Deacetylases in Human Tumorigenesis: The Paradigm of Urothelial Bladder Cancer.

Giannopoulou AF, Velentzas AD, Konstantakou EG, Avgeris M, Katarachia SA, Papandreou NC, Kalavros NI, Mpakou VE, Iconomidou V, Anastasiadou E, Kostakis IK, Papassideri IS, Voutsinas GE, Scorilas A, Stravopodis DJ.

Int J Mol Sci. 2019 Mar 14;20(6). pii: E1291. doi: 10.3390/ijms20061291. Review.

3.

Functional characterization of CHEK2 variants in a Saccharomyces cerevisiae system.

Delimitsou A, Fostira F, Kalfakakou D, Apostolou P, Konstantopoulou I, Kroupis C, Papavassiliou AG, Kleibl Z, Stratikos E, Voutsinas GE, Yannoukakos D.

Hum Mutat. 2019 May;40(5):631-648. doi: 10.1002/humu.23728. Epub 2019 Mar 9.

PMID:
30851065
4.

Gene-Specific Intron Retention Serves as Molecular Signature that Distinguishes Melanoma from Non-Melanoma Cancer Cells in Greek Patients.

Giannopoulou AF, Konstantakou EG, Velentzas AD, Avgeris SN, Avgeris M, Papandreou NC, Zoi I, Filippa V, Katarachia S, Lampidonis AD, Prombona A, Syntichaki P, Piperi C, Basdra EK, Iconomidou V, Papadavid E, Anastasiadou E, Papassideri IS, Papavassiliou AG, Voutsinas GE, Scorilas A, Stravopodis DJ.

Int J Mol Sci. 2019 Feb 21;20(4). pii: E937. doi: 10.3390/ijms20040937.

5.

Resistance to Fas-Mediated Apoptosis Does Not Correlate to Structural Alterations or Expression Changes of the Death Receptor in Papillary Thyroid Carcinomas.

Fanourakis, Saetta AA, Lazaris AC, Miaouli M, Voutsinas GE, Patsouris E, Tseleni-Balafouta S.

Pathobiology. 2018;85(5-6):304-310. doi: 10.1159/000492358. Epub 2018 Oct 2.

PMID:
30278467
6.

Mutational analysis of TSC1 and TSC2 genes in Tuberous Sclerosis Complex patients from Greece.

Avgeris S, Fostira F, Vagena A, Ninios Y, Delimitsou A, Vodicka R, Vrtel R, Youroukos S, Stravopodis DJ, Vlassi M, Astrinidis A, Yannoukakos D, Voutsinas GE.

Sci Rep. 2017 Dec 1;7(1):16697. doi: 10.1038/s41598-017-16988-w.

7.

Unraveling the human protein atlas of metastatic melanoma in the course of ultraviolet radiation-derived photo-therapy.

Konstantakou EG, Velentzas AD, Anagnostopoulos AK, Giannopoulou AF, Anastasiadou E, Papassideri IS, Voutsinas GE, Tsangaris GT, Stravopodis DJ.

J Proteomics. 2018 Sep 30;188:119-138. doi: 10.1016/j.jprot.2017.11.015. Epub 2017 Nov 24.

PMID:
29180045
8.

Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets.

Konstantakou EG, Velentzas AD, Anagnostopoulos AK, Litou ZI, Konstandi OA, Giannopoulou AF, Anastasiadou E, Voutsinas GE, Tsangaris GT, Stravopodis DJ.

PLoS One. 2017 Feb 3;12(2):e0171512. doi: 10.1371/journal.pone.0171512. eCollection 2017.

9.

Evidence for APOBEC3B mRNA and protein expression in oral squamous cell carcinomas.

Fanourakis G, Tosios K, Papanikolaou N, Chatzistamou I, Xydous M, Tseleni-Balafouta S, Sklavounou A, Voutsinas GE, Vastardis H.

Exp Mol Pathol. 2016 Dec;101(3):314-319. doi: 10.1016/j.yexmp.2016.11.001. Epub 2016 Nov 4.

PMID:
27818121
10.

17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.

Karkoulis PK, Stravopodis DJ, Voutsinas GE.

Tumour Biol. 2016 May;37(5):6861-73. doi: 10.1007/s13277-015-4544-2. Epub 2015 Dec 11.

PMID:
26662567
11.

3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants.

Konstantakou EG, Voutsinas GE, Velentzas AD, Basogianni AS, Paronis E, Balafas E, Kostomitsopoulos N, Syrigos KN, Anastasiadou E, Stravopodis DJ.

Mol Cancer. 2015 Jul 22;14:135. doi: 10.1186/s12943-015-0399-9.

12.

CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.

Apostolou P, Fostira F, Papamentzelopoulou M, Michelli M, Panopoulos C, Fountzilas G, Konstantopoulou I, Voutsinas GE, Yannoukakos D.

Cancer Genet. 2015 Apr;208(4):129-34. doi: 10.1016/j.cancergen.2015.02.006. Epub 2015 Feb 20.

PMID:
25835597
13.

Genetic evaluation based on family history and Her2 status correctly identifies TP53 mutations in very early onset breast cancer cases.

Fostira F, Konstantopoulou I, Mavroudis D, Tryfonopoulos D, Yannoukakos D, Voutsinas GE.

Clin Genet. 2015 Apr;87(4):383-7. doi: 10.1111/cge.12397. Epub 2014 Apr 29.

PMID:
24702488
14.

Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer cases.

Stavropoulou AV, Fostira F, Pertesi M, Tsitlaidou M, Voutsinas GE, Triantafyllidou O, Bamias A, Dimopoulos MA, Timotheadou E, Pectasides D, Christodoulou C, Klouvas G, Papadimitriou C, Makatsoris T, Pentheroudakis G, Aravantinos G, Karydakis V, Yannoukakos D, Fountzilas G, Konstantopoulou I.

PLoS One. 2013;8(3):e58182. doi: 10.1371/journal.pone.0058182. Epub 2013 Mar 11. Erratum in: PLoS One. 2013;8(4). doi:10.1371/annotation/159f0ba3-5a24-4de9-99be-1cd6d5037760.

15.
16.

Correlation of CYP1A1, GSTP1 and GSTM1 gene polymorphisms and lung cancer risk among smokers.

Pliarchopoulou K, Voutsinas G, Papaxoinis G, Florou K, Skondra M, Kostaki K, Roussou P, Syrigos K, Pectasides D.

Oncol Lett. 2012 Jun;3(6):1301-1306. Epub 2012 Mar 30.

17.

The resurgence of Hormone-Sensitive Lipase (HSL) in mammalian lipolysis.

Lampidonis AD, Rogdakis E, Voutsinas GE, Stravopodis DJ.

Gene. 2011 May 15;477(1-2):1-11. doi: 10.1016/j.gene.2011.01.007. Epub 2011 Jan 15. Review.

PMID:
21241784
18.
19.

Thymidylate synthase inhibition induces p53-dependent and p53-independent apoptotic responses in human urinary bladder cancer cells.

Stravopodis DJ, Karkoulis PK, Konstantakou EG, Melachroinou S, Thanasopoulou A, Aravantinos G, Margaritis LH, Anastasiadou E, Voutsinas GE.

J Cancer Res Clin Oncol. 2011 Feb;137(2):359-74. doi: 10.1007/s00432-010-0891-y. Epub 2010 Apr 28.

PMID:
20425122
20.

Allelic imbalance of expression and epigenetic regulation within the alpha-synuclein wild-type and p.Ala53Thr alleles in Parkinson disease.

Voutsinas GE, Stavrou EF, Karousos G, Dasoula A, Papachatzopoulou A, Syrrou M, Verkerk AJ, van der Spek P, Patrinos GP, Stöger R, Athanassiadou A.

Hum Mutat. 2010 Jun;31(6):685-91. doi: 10.1002/humu.21248.

PMID:
20340137
21.

Mutational and immunohistochemical study of the PI3K/Akt pathway in papillary thyroid carcinoma in Greece.

Sozopoulos E, Litsiou H, Voutsinas G, Mitsiades N, Anagnostakis N, Tseva T, Patsouris E, Tseleni-Balafouta S.

Endocr Pathol. 2010 Jun;21(2):90-100. doi: 10.1007/s12022-010-9112-0.

PMID:
20186503
22.

Molecular targeting and gene delivery in bladder cancer therapy.

Voutsinas GE, Stravopodis DJ.

J BUON. 2009 Sep;14 Suppl 1:S69-78. Review.

23.

Human bladder cancer cells undergo cisplatin-induced apoptosis that is associated with p53-dependent and p53-independent responses.

Konstantakou EG, Voutsinas GE, Karkoulis PK, Aravantinos G, Margaritis LH, Stravopodis DJ.

Int J Oncol. 2009 Aug;35(2):401-16.

PMID:
19578756
24.

Mutational analysis of the BRAF, RAS and EGFR genes in human adrenocortical carcinomas.

Kotoula V, Sozopoulos E, Litsiou H, Fanourakis G, Koletsa T, Voutsinas G, Tseleni-Balafouta S, Mitsiades CS, Wellmann A, Mitsiades N.

Endocr Relat Cancer. 2009 Jun;16(2):565-72. doi: 10.1677/ERC-08-0101. Epub 2009 Feb 3.

PMID:
19190079
25.

Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines.

Stravopodis DJ, Karkoulis PK, Konstantakou EG, Melachroinou S, Lampidonis AD, Anastasiou D, Kachrilas S, Messini-Nikolaki N, Papassideri IS, Aravantinos G, Margaritis LH, Voutsinas GE.

Int J Oncol. 2009 Jan;34(1):137-60.

PMID:
19082486
26.

Cloning and functional characterization of the 5' regulatory region of ovine Hormone Sensitive Lipase (HSL) gene.

Lampidonis AD, Stravopodis DJ, Voutsinas GE, Messini-Nikolaki N, Stefos GC, Margaritis LH, Argyrokastritis A, Bizelis I, Rogdakis E.

Gene. 2008 Dec 31;427(1-2):65-79. doi: 10.1016/j.gene.2008.09.001. Epub 2008 Sep 11.

PMID:
18824087
27.

Imatinib mesylate inhibits proliferation and exerts an antifibrotic effect in human breast stroma fibroblasts.

Gioni V, Karampinas T, Voutsinas G, Roussidis AE, Papadopoulos S, Karamanos NK, Kletsas D.

Mol Cancer Res. 2008 May;6(5):706-14. doi: 10.1158/1541-7786.MCR-07-0355.

28.

A PCR-based integrated protocol for the structural analysis of the 13th exon of the human beta-myosin heavy chain gene (MYH7): development of a diagnostic tool for HCM disease.

Stravopodis DJ, Zapheiropoulos AZ, Voutsinas G, Margaritis LH, Papassideri IS.

Exp Mol Pathol. 2008 Jun;84(3):245-50. doi: 10.1016/j.yexmp.2008.03.014. Epub 2008 Apr 16.

PMID:
18499102
29.

Cloning and functional characterization of the ovine Hormone Sensitive Lipase (HSL) full-length cDNAs: an integrated approach.

Lampidonis AD, Argyrokastritis A, Stravopodis DJ, Voutsinas GE, Ntouroupi TG, Margaritis LH, Bizelis I, Rogdakis E.

Gene. 2008 Jun 15;416(1-2):30-43. doi: 10.1016/j.gene.2008.02.026. Epub 2008 Mar 12.

PMID:
18436396
30.

Low frequency of the glutathione-S-transferase T1-null genotype in patients with primary myelodysplastic syndrome and 5q deletion.

Stavropoulou C, Sambani C, Rigana H, Georgakakos VN, Voutsinas G, Manola KN, Pantelias GE, Makropoulos V; Hellenic MDS Study Group.

Leukemia. 2008 Aug;22(8):1643-6. doi: 10.1038/leu.2008.35. Epub 2008 Feb 28. No abstract available.

PMID:
18305556
31.

Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.

Stravopodis DJ, Margaritis LH, Voutsinas GE.

Curr Med Chem. 2007;14(29):3122-38. Review.

PMID:
18220746
32.

Glutathione-S-transferase T1 and M1 gene polymorphisms in Greek patients with multiple sclerosis: a pilot study.

Stavropoulou C, Korakaki D, Rigana H, Voutsinas G, Polyzoi M, Georgakakos VN, Manola KN, Karageorgiou CE, Sambani C.

Eur J Neurol. 2007 May;14(5):572-4.

PMID:
17437619
33.

Targeting BRAFV600E in thyroid carcinoma: therapeutic implications.

Mitsiades CS, Negri J, McMullan C, McMillin DW, Sozopoulos E, Fanourakis G, Voutsinas G, Tseleni-Balafouta S, Poulaki V, Batt D, Mitsiades N.

Mol Cancer Ther. 2007 Mar;6(3):1070-8.

34.

Epidermal growth factor receptor as a therapeutic target in human thyroid carcinoma: mutational and functional analysis.

Mitsiades CS, Kotoula V, Poulaki V, Sozopoulos E, Negri J, Charalambous E, Fanourakis G, Voutsinas G, Tseleni-Balafouta S, Mitsiades N.

J Clin Endocrinol Metab. 2006 Sep;91(9):3662-6. Epub 2006 Jul 5.

PMID:
16822827
35.

Fas signaling in thyroid carcinomas is diverted from apoptosis to proliferation.

Mitsiades CS, Poulaki V, Fanourakis G, Sozopoulos E, McMillin D, Wen Z, Voutsinas G, Tseleni-Balafouta S, Mitsiades N.

Clin Cancer Res. 2006 Jun 15;12(12):3705-12.

36.

Fibrillin expression and localization in various types of carcinomas of the thyroid gland.

Tseleni-Balafouta S, Gakiopoulou H, Fanourakis G, Voutsinas G, Litsiou H, Sozopoulos E, Balafoutas D, Patsouris E.

Mod Pathol. 2006 May;19(5):695-700.

37.

Tenascin-C protein expression and mRNA splice variants in thyroid carcinoma.

Tseleni-Balafouta S, Gakiopoulou H, Fanourakis G, Voutsinas G, Balafoutas D, Patsouris E.

Exp Mol Pathol. 2006 Apr;80(2):177-82. Epub 2005 Nov 2.

PMID:
16259977
38.

Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing.

Poulaki V, Mitsiades CS, McMullan C, Fanourakis G, Negri J, Goudopoulou A, Halikias IX, Voutsinas G, Tseleni-Balafouta S, Miller JW, Mitsiades N.

Invest Ophthalmol Vis Sci. 2005 Jan;46(1):358-66.

PMID:
15623796
39.

mRNA assessment for procollagen production in women with genuine stress urinary incontinence.

Bakas PG, Liapis AE, Zervolea I, Voutsinas G, Kletsas D, Creatsas G.

Int Urogynecol J Pelvic Floor Dysfunct. 2004 Nov-Dec;15(6):429-31; discussion 431. Epub 2004 Jun 9.

PMID:
15549263
40.

Mononucleotide markers of microsatellite instability in carcinomas of the urinary bladder.

Saetta AA, Goudopoulou A, Korkolopoulou P, Voutsinas G, Thomas-Tsagli E, Michalopoulos NV, Patsouris E.

Eur J Surg Oncol. 2004 Sep;30(7):796-803.

PMID:
15296997
41.

c-FLIP expression in bladder urothelial carcinomas: its role in resistance to Fas-mediated apoptosis and clinicopathologic correlations.

Korkolopoulou P, Goudopoulou A, Voutsinas G, Thomas-Tsagli E, Kapralos P, Patsouris E, Saetta AA.

Urology. 2004 Jun;63(6):1198-204.

PMID:
15183989
42.

Lack of Fas (APO-1/CD95) gene structural alterations or transcript variant ratio changes in breast cancer.

Puiu L, Petrakou E, Apostolidou A, Athanassiadou A, Psiouri L, Papachatzopoulou A, Gorgoulis VG, Kotsinas A, Tzoracoeleftherakis E, Maniatis GM, Voutsinas G.

Cancer Lett. 2003 May 8;194(1):91-7.

PMID:
12706862
43.

Detection of genetic abnormalities in neoplasms from Greek patients with FAP.

Michalopoulos NV, Saetta A, Lazaris ACh, Voutsinas G, Davaris PS.

Eur J Surg Oncol. 2003 Feb;29(1):38-43.

PMID:
12559075
44.

Mutagenesis, apoptosis, basic relation to carcinogenic models.

Voutsinas G.

Folia Histochem Cytobiol. 2001;39 Suppl 2:56-7. Review.

PMID:
11820628
45.

Bladder cancer mortality in the Epirus district population (Greece).

Baltogiannis D, Tasos A, Voutsinas G, Dauaher H, Chambilomatis P, Giannakopoulos X.

Int Urol Nephrol. 2001;32(3):377-9.

PMID:
11583356
46.

Genetic analysis of families with Parkinson disease that carry the Ala53Thr mutation in the gene encoding alpha-synuclein.

Athanassiadou A, Voutsinas G, Psiouri L, Leroy E, Polymeropoulos MH, Ilias A, Maniatis GM, Papapetropoulos T.

Am J Hum Genet. 1999 Aug;65(2):555-8. No abstract available.

47.

A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3.

Timmer T, Terpstra P, van den Berg A, Veldhuis PM, Ter Elst A, Voutsinas G, Hulsbeek MM, Draaijers TG, Looman MW, Kok K, Naylor SL, Buys CH.

Eur J Hum Genet. 1999 May-Jun;7(4):478-86.

48.

Specific recombinogenic activity of a new polyene antibiotic.

Vachkova R, Kappas A, Tyagunenko E, Markaki M, Voutsinas G.

Cell Mol Life Sci. 1998 Feb;54(2):143-7.

PMID:
9539955
49.
50.

Antimutagenicity of three isomers of aminobenzoic acid in Salmonella typhimurium.

Gichner T, Voutsinas G, Patrineli A, Kappas A, Plewa MJ.

Mutat Res. 1994 Sep 1;309(2):201-10.

PMID:
7520977

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