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Items: 13


Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-dependent upregulation of glutathione synthesis.

He Y, Jackman NA, Thorn TL, Vought VE, Hewett SJ.

Glia. 2015 Sep;63(9):1568-80. doi: 10.1002/glia.22828. Epub 2015 Apr 16.


A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.

Shinsky SA, Hu M, Vought VE, Ng SB, Bamshad MJ, Shendure J, Cosgrove MS.

J Mol Biol. 2014 Jun 12;426(12):2283-99. doi: 10.1016/j.jmb.2014.03.011. Epub 2014 Mar 27.


Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.

Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.

J Biol Chem. 2014 Jan 10;289(2):868-84. doi: 10.1074/jbc.M113.501064. Epub 2013 Nov 14.


Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the C. elegans germline.

Fox PM, Vought VE, Hanazawa M, Lee MH, Maine EM, Schedl T.

Development. 2011 Jun;138(11):2223-34. doi: 10.1242/dev.059535.


Myosin5a tail associates directly with Rab3A-containing compartments in neurons.

Wöllert T, Patel A, Lee YL, Provance DW Jr, Vought VE, Cosgrove MS, Mercer JA, Langford GM.

J Biol Chem. 2011 Apr 22;286(16):14352-61. doi: 10.1074/jbc.M110.187286. Epub 2011 Feb 23.


A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.

Patel A, Vought VE, Dharmarajan V, Cosgrove MS.

J Biol Chem. 2011 Feb 4;286(5):3359-69. doi: 10.1074/jbc.M110.174524. Epub 2010 Nov 24. Erratum in: J Biol Chem. 2011 May 20;286(20):18344.


On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

Patel A, Dharmarajan V, Vought VE, Cosgrove MS.

J Biol Chem. 2009 Sep 4;284(36):24242-56. doi: 10.1074/jbc.M109.014498. Epub 2009 Jun 25.


A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.

Patel A, Vought VE, Dharmarajan V, Cosgrove MS.

J Biol Chem. 2008 Nov 21;283(47):32162-75. doi: 10.1074/jbc.M806317200. Epub 2008 Oct 1.


EGO-1, a putative RNA-dependent RNA polymerase, is required for heterochromatin assembly on unpaired dna during C. elegans meiosis.

Maine EM, Hauth J, Ratliff T, Vought VE, She X, Kelly WG.

Curr Biol. 2005 Nov 8;15(21):1972-8.


Caenorhabditis elegans atx-2 promotes germline proliferation and the oocyte fate.

Maine EM, Hansen D, Springer D, Vought VE.

Genetics. 2004 Oct;168(2):817-30.

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