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Items: 43


A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models.

Boutin ME, Voss TC, Titus SA, Cruz-Gutierrez K, Michael S, Ferrer M.

Sci Rep. 2018 Jul 24;8(1):11135. doi: 10.1038/s41598-018-29169-0.


The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

Baranes-Bachar K, Levy-Barda A, Oehler J, Reid DA, Soria-Bretones I, Voss TC, Chung D, Park Y, Liu C, Yoon JB, Li W, Dellaire G, Misteli T, Huertas P, Rothenberg E, Ramadan K, Ziv Y, Shiloh Y.

Mol Cell. 2018 Mar 1;69(5):866-878.e7. doi: 10.1016/j.molcel.2018.02.002.


Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.

Veschi V, Liu Z, Voss TC, Ozbun L, Gryder B, Yan C, Hu Y, Ma A, Jin J, Mazur SJ, Lam N, Souza BK, Giannini G, Hager GL, Arrowsmith CH, Khan J, Appella E, Thiele CJ.

Cancer Cell. 2017 Jan 9;31(1):50-63. doi: 10.1016/j.ccell.2016.12.002.


Repression of the Antioxidant NRF2 Pathway in Premature Aging.

Kubben N, Zhang W, Wang L, Voss TC, Yang J, Qu J, Liu GH, Misteli T.

Cell. 2016 Jun 2;165(6):1361-1374. doi: 10.1016/j.cell.2016.05.017.


High-throughput imaging: Focusing in on drug discovery in 3D.

Li L, Zhou Q, Voss TC, Quick KL, LaBarbera DV.

Methods. 2016 Mar 1;96:97-102. doi: 10.1016/j.ymeth.2015.11.013. Epub 2015 Nov 21. Review.


Identification of Gene Positioning Factors Using High-Throughput Imaging Mapping.

Shachar S, Voss TC, Pegoraro G, Sciascia N, Misteli T.

Cell. 2015 Aug 13;162(4):911-23. doi: 10.1016/j.cell.2015.07.035.


Cell cycle staging of individual cells by fluorescence microscopy.

Roukos V, Pegoraro G, Voss TC, Misteli T.

Nat Protoc. 2015 Feb;10(2):334-48. doi: 10.1038/nprot.2015.016. Epub 2015 Jan 29.


Identification by high-throughput imaging of the histone methyltransferase EHMT2 as an epigenetic regulator of VEGFA alternative splicing.

Salton M, Voss TC, Misteli T.

Nucleic Acids Res. 2014 Dec 16;42(22):13662-73. doi: 10.1093/nar/gku1226. Epub 2014 Nov 20.


Dynamic regulation of transcriptional states by chromatin and transcription factors.

Voss TC, Hager GL.

Nat Rev Genet. 2014 Feb;15(2):69-81. doi: 10.1038/nrg3623. Epub 2013 Dec 17. Review.


High-throughput fluorescence-based screen to identify factors involved in nuclear receptor recruitment to response elements.

Miranda TB, Voss TC, Hager GL.

Methods Mol Biol. 2013;1042:3-12. doi: 10.1007/978-1-62703-526-2_1.


Spatial dynamics of chromosome translocations in living cells.

Roukos V, Voss TC, Schmidt CK, Lee S, Wangsa D, Misteli T.

Science. 2013 Aug 9;341(6146):660-4. doi: 10.1126/science.1237150.


Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level.

Miranda TB, Voss TC, Sung MH, Baek S, John S, Hawkins M, Grøntved L, Schiltz RL, Hager GL.

Cancer Res. 2013 Aug 15;73(16):5130-9. doi: 10.1158/0008-5472.CAN-13-0742. Epub 2013 Jun 26.


Prevalent glucocorticoid and androgen activity in US water sources.

Stavreva DA, George AA, Klausmeyer P, Varticovski L, Sack D, Voss TC, Schiltz RL, Blazer VS, Iwanowicz LR, Hager GL.

Sci Rep. 2012;2:937. doi: 10.1038/srep00937. Epub 2012 Dec 6.


Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation.

Hakim O, Sung MH, Nakayamada S, Voss TC, Baek S, Hager GL.

Genome Res. 2013 Mar;23(3):462-72. doi: 10.1101/gr.147652.112. Epub 2012 Dec 3.


Identification of mammalian protein quality control factors by high-throughput cellular imaging.

Pegoraro G, Voss TC, Martin SE, Tuzmen P, Guha R, Misteli T.

PLoS One. 2012;7(2):e31684. doi: 10.1371/journal.pone.0031684. Epub 2012 Feb 20.


DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.

Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, Nussenzweig A, Hager GL, Nussenzweig MC, Casellas R.

Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909.


Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism.

Voss TC, Schiltz RL, Sung MH, Yen PM, Stamatoyannopoulos JA, Biddie SC, Johnson TA, Miranda TB, John S, Hager GL.

Cell. 2011 Aug 19;146(4):544-54. doi: 10.1016/j.cell.2011.07.006. Epub 2011 Aug 11.


Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements.

Hakim O, Sung MH, Voss TC, Splinter E, John S, Sabo PJ, Thurman RE, Stamatoyannopoulos JA, de Laat W, Hager GL.

Genome Res. 2011 May;21(5):697-706. doi: 10.1101/gr.111153.110. Epub 2011 Apr 6.


Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription.

Stavreva DA, Wiench M, John S, Conway-Campbell BL, McKenna MA, Pooley JR, Johnson TA, Voss TC, Lightman SL, Hager GL.

Nat Cell Biol. 2009 Sep;11(9):1093-102. doi: 10.1038/ncb1922. Epub 2009 Aug 16.


Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity.

Voss TC, Schiltz RL, Sung MH, Johnson TA, John S, Hager GL.

J Cell Sci. 2009 Feb 1;122(Pt 3):345-56. doi: 10.1242/jcs.035865. Epub 2009 Jan 6.


Dynamic effect of bortezomib on nuclear factor-kappaB activity and gene expression in tumor cells.

Sung MH, Bagain L, Chen Z, Karpova T, Yang X, Silvin C, Voss TC, McNally JG, Van Waes C, Hager GL.

Mol Pharmacol. 2008 Nov;74(5):1215-22. doi: 10.1124/mol.108.049114. Epub 2008 Aug 6.


Visualizing chromatin dynamics in intact cells.

Voss TC, Hager GL.

Biochim Biophys Acta. 2008 Nov;1783(11):2044-51. doi: 10.1016/j.bbamcr.2008.06.022. Epub 2008 Jul 16. Review.


cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression.

Rodriguez-Collazo P, Snyder SK, Chiffer RC, Bressler EA, Voss TC, Anderson EP, Genieser HG, Smith CL.

Exp Cell Res. 2008 Sep 10;314(15):2855-69. doi: 10.1016/j.yexcr.2008.06.022. Epub 2008 Jul 8.


Interaction of the glucocorticoid receptor with the chromatin landscape.

John S, Sabo PJ, Johnson TA, Sung MH, Biddie SC, Lightman SL, Voss TC, Davis SR, Meltzer PS, Stamatoyannopoulos JA, Hager GL.

Mol Cell. 2008 Mar 14;29(5):611-24. doi: 10.1016/j.molcel.2008.02.010.


Dynamic interactions between Pit-1 and C/EBPalpha in the pituitary cell nucleus.

Demarco IA, Voss TC, Booker CF, Day RN.

Mol Cell Biol. 2006 Nov;26(21):8087-98. Epub 2006 Aug 14.


Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus.

Voss TC, Demarco IA, Booker CF, Day RN.

J Cell Sci. 2005 Aug 1;118(Pt 15):3277-88. Epub 2005 Jul 19.


Quantitative imaging of protein interactions in the cell nucleus.

Voss TC, Demarco IA, Day RN.

Biotechniques. 2005 Mar;38(3):413-24. Review.


Corepressor subnuclear organization is regulated by estrogen receptor via a mechanism that requires the DNA-binding domain.

Voss TC, Demarco IA, Booker CF, Day RN.

Mol Cell Endocrinol. 2005 Feb 28;231(1-2):33-47.


Imaging the localized protein interactions between Pit-1 and the CCAAT/enhancer binding protein alpha in the living pituitary cell nucleus.

Day RN, Voss TC, Enwright JF 3rd, Booker CF, Periasamy A, Schaufele F.

Mol Endocrinol. 2003 Mar;17(3):333-45. Epub 2002 Dec 12.


Editorial: Pitx-2 mutants and somatolactotroph gene regulation--deciphering the combinatorial code.

Voss TC, Day RN.

Endocrinology. 2002 Aug;143(8):2836-8. No abstract available.


GH mRNA levels are elevated by forskolin but not GH releasing hormone in GHRH receptor-expressing MtT/S somatotroph cell line.

Voss TC, Goldman LR, Seek SL, Miller TL, Mayo KE, Somogyvari-Vigh A, Arimura A, Hurley DL.

Mol Cell Endocrinol. 2001 Feb 14;172(1-2):125-34.


Mouse growth hormone transcription factor Zn-16: unique bipartite structure containing tandemly repeated zinc finger domains not reported in rat Zn-15.

VanderHeyden TC, Wojtkiewicz PW, Voss TC, Mangin TM, Harrelson Z, Ahlers KM, Phelps CJ, Hurley DL.

Mol Cell Endocrinol. 2000 Jan 25;159(1-2):89-98.


Limitations to tobacco mosaic virus infection of turnip.

Zhang Y, Lartey RT, Hartson SD, Voss TC, Melcher U.

Arch Virol. 1999;144(5):957-71.


Clinical and molecular characterization of a Brazilian patient with Pit-1 deficiency.

Arnhold IJ, Nery M, Brown MR, Voss TC, VanderHeyden TC, Adess ME, Hurley DL, Wajchenberg BL, Parks JS.

J Pediatr Endocrinol Metab. 1998 Sep-Oct;11(5):623-30.


Central hypothyroidism reveals compound heterozygous mutations in the Pit-1 gene.

Brown MR, Parks JS, Adess ME, Rich BH, Rosenthal IM, Voss TC, VanderHeyden TC, Hurley DL.

Horm Res. 1998;49(2):98-102.


Tobamovirus evolution: gene overlaps, recombination, and taxonomic implications.

Lartey RT, Voss TC, Melcher U.

Mol Biol Evol. 1996 Dec;13(10):1327-38.


Completion of a cDNA sequence from a tobamovirus pathogenic to crucifers.

Lartey RT, Voss TC, Melcher U.

Gene. 1995 Dec 12;166(2):331-2. Erratum in: Gene 1997 Apr 1;188(2):295.


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