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Items: 1 to 50 of 92

1.

Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.

Klein BJ, Jang SM, Lachance C, Mi W, Lyu J, Sakuraba S, Krajewski K, Wang WW, Sidoli S, Liu J, Zhang Y, Wang X, Warfield BM, Kueh AJ, Voss AK, Thomas T, Garcia BA, Liu WR, Strahl BD, Kono H, Li W, Shi X, Côté J, Kutateladze TG.

Nat Commun. 2019 Oct 17;10(1):4724. doi: 10.1038/s41467-019-12551-5.

2.

MOZ directs the distal-less homeobox gene expression program during craniofacial development.

Vanyai HK, Garnham A, May RE, McRae HM, Collin C, Wilcox S, Smyth GK, Thomas T, Voss AK.

Development. 2019 Jul 24;146(14). pii: dev175042. doi: 10.1242/dev.175042.

PMID:
31340933
3.

Are transplantable stem cells required for adult hematopoiesis?

McRae HM, Voss AK, Thomas T.

Exp Hematol. 2019 Jul;75:1-10. doi: 10.1016/j.exphem.2019.05.007. Epub 2019 Jun 5. Review.

PMID:
31175894
4.

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.

Delbridge ARD, Kueh AJ, Ke F, Zamudio NM, El-Saafin F, Jansz N, Wang GY, Iminitoff M, Beck T, Haupt S, Hu Y, May RE, Whitehead L, Tai L, Chiang W, Herold MJ, Haupt Y, Smyth GK, Thomas T, Blewitt ME, Strasser A, Voss AK.

Cell Rep. 2019 Apr 9;27(2):442-454.e5. doi: 10.1016/j.celrep.2019.03.048.

5.

Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment.

Urdinguio RG, Lopez V, Bayón GF, Diaz de la Guardia R, Sierra MI, García-Toraño E, Perez RF, García MG, Carella A, Pruneda PC, Prieto C, Dmitrijeva M, Santamarina P, Belmonte T, Mangas C, Diaconu E, Ferrero C, Tejedor JR, Fernandez-Morera JL, Bravo C, Bueno C, Sanjuan-Pla A, Rodriguez RM, Suarez-Alvarez B, López-Larrea C, Bernal T, Colado E, Balbín M, García-Suarez O, Chiara MD, Sáenz-de-Santa-María I, Rodríguez F, Pando-Sandoval A, Rodrigo L, Santos L, Salas A, Vallejo-Díaz J, C Carrera A, Rico D, Hernández-López I, Vayá A, Ricart JM, Seto E, Sima-Teruel N, Vaquero A, Valledor L, Cañal MJ, Pisano D, Graña-Castro O, Thomas T, Voss AK, Menéndez P, Villar-Garea A, Deutzmann R, Fernandez AF, Fraga MF.

Nucleic Acids Res. 2019 Jun 4;47(10):5016-5037. doi: 10.1093/nar/gkz195.

6.

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.

McRae HM, Garnham AL, Hu Y, Witkowski MT, Corbett MA, Dixon MP, May RE, Sheikh BN, Chiang W, Kueh AJ, Nguyen TA, Man K, Gloury R, Aubrey BJ, Policheni A, Di Rago L, Alexander WS, Gray DHD, Strasser A, Hawkins ED, Wilcox S, Gécz J, Kallies A, McCormack MP, Smyth GK, Voss AK, Thomas T.

Blood. 2019 Apr 18;133(16):1729-1741. doi: 10.1182/blood-2018-07-860726. Epub 2019 Feb 12.

7.

Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development.

Aubrey BJ, Janic A, Chen Y, Chang C, Lieschke EC, Diepstraten ST, Kueh AJ, Bernardini JP, Dewson G, O'Reilly LA, Whitehead L, Voss AK, Smyth GK, Strasser A, Kelly GL.

Genes Dev. 2018 Nov 1;32(21-22):1420-1429. doi: 10.1101/gad.314286.118. Epub 2018 Oct 26.

8.

Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities.

Grabow S, Kueh AJ, Ke F, Vanyai HK, Sheikh BN, Dengler MA, Chiang W, Eccles S, Smyth IM, Jones LK, de Sauvage FJ, Scott M, Whitehead L, Voss AK, Strasser A.

Cell Rep. 2018 Sep 18;24(12):3285-3295.e4. doi: 10.1016/j.celrep.2018.08.048.

9.

Histone Lysine and Genomic Targets of Histone Acetyltransferases in Mammals.

Voss AK, Thomas T.

Bioessays. 2018 Oct;40(10):e1800078. doi: 10.1002/bies.201800078. Epub 2018 Aug 24. Review.

PMID:
30144132
10.

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.

Baell JB, Leaver DJ, Hermans SJ, Kelly GL, Brennan MS, Downer NL, Nguyen N, Wichmann J, McRae HM, Yang Y, Cleary B, Lagiakos HR, Mieruszynski S, Pacini G, Vanyai HK, Bergamasco MI, May RE, Davey BK, Morgan KJ, Sealey AJ, Wang B, Zamudio N, Wilcox S, Garnham AL, Sheikh BN, Aubrey BJ, Doggett K, Chung MC, de Silva M, Bentley J, Pilling P, Hattarki M, Dolezal O, Dennis ML, Falk H, Ren B, Charman SA, White KL, Rautela J, Newbold A, Hawkins ED, Johnstone RW, Huntington ND, Peat TS, Heath JK, Strasser A, Parker MW, Smyth GK, Street IP, Monahan BJ, Voss AK, Thomas T.

Nature. 2018 Aug;560(7717):253-257. doi: 10.1038/s41586-018-0387-5. Epub 2018 Aug 1.

PMID:
30069049
11.

Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK.

Ke FFS, Vanyai HK, Cowan AD, Delbridge ARD, Whitehead L, Grabow S, Czabotar PE, Voss AK, Strasser A.

Cell. 2018 May 17;173(5):1217-1230.e17. doi: 10.1016/j.cell.2018.04.036.

12.

Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription.

El-Saafin F, Curry C, Ye T, Garnier JM, Kolb-Cheynel I, Stierle M, Downer NL, Dixon MP, Negroni L, Berger I, Thomas T, Voss AK, Dobyns W, Devys D, Tora L.

Hum Mol Genet. 2018 Jun 15;27(12):2171-2186. doi: 10.1093/hmg/ddy126.

13.

Implementing augmentative and alternative communication in critical care settings: Perspectives of healthcare professionals.

Handberg C, Voss AK.

J Clin Nurs. 2018 Jan;27(1-2):102-114. doi: 10.1111/jocn.13851. Epub 2017 Jun 20.

PMID:
28401613
14.

MOZ and BMI1 act synergistically to maintain hematopoietic stem cells.

Sheikh BN, Metcalf D, Voss AK, Thomas T.

Exp Hematol. 2017 Mar;47:83-97.e8. doi: 10.1016/j.exphem.2016.10.006. Epub 2016 Oct 24.

PMID:
27773671
15.

Essential role for the histone acetyltransferase KAT7 in T cell development, fitness, and survival.

Newman DM, Voss AK, Thomas T, Allan RS.

J Leukoc Biol. 2017 Apr;101(4):887-892. doi: 10.1189/jlb.1MA0816-338R. Epub 2016 Oct 12.

PMID:
27733580
16.

MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells.

Sheikh BN, Yang Y, Schreuder J, Nilsson SK, Bilardi R, Carotta S, McRae HM, Metcalf D, Voss AK, Thomas T.

Blood. 2016 Nov 10;128(19):2307-2318. doi: 10.1182/blood-2015-10-676072. Epub 2016 Sep 23.

PMID:
27663673
17.

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Newman DM, Sakaguchi S, Lun A, Preston S, Pellegrini M, Khamina K, Bergthaler A, Nutt SL, Smyth GK, Voss AK, Thomas T, Ellmeier W, Belz GT, Allan RS.

Cell Rep. 2016 Sep 20;16(12):3311-3321. doi: 10.1016/j.celrep.2016.08.056.

18.

Cortical Layer Inversion and Deregulation of Reelin Signaling in the Absence of SOCS6 and SOCS7.

Lawrenson ID, Krebs DL, Linossi EM, Zhang JG, McLennan TJ, Collin C, McRae HM, Kolesnik TB, Koh K, Britto JM, Kueh AJ, Sheikh BN, El-Saafin F, Nicola NA, Tan SS, Babon JJ, Nicholson SE, Alexander WS, Thomas T, Voss AK.

Cereb Cortex. 2017 Jan 1;27(1):576-588. doi: 10.1093/cercor/bhv253.

PMID:
26503265
19.

Response to Heard et al.

Moulin M, Voss AK, Thomas T, Wong WW, Cook WD, Koentgen F, Vince J, Silke J, Vaux DL.

EMBO J. 2015 Oct 1;34(19):2396-7. doi: 10.15252/embj.201592761. No abstract available.

20.

MOF maintains transcriptional programs regulating cellular stress response.

Sheikh BN, Bechtel-Walz W, Lucci J, Karpiuk O, Hild I, Hartleben B, Vornweg J, Helmstädter M, Sahyoun AH, Bhardwaj V, Stehle T, Diehl S, Kretz O, Voss AK, Thomas T, Manke T, Huber TB, Akhtar A.

Oncogene. 2016 May;35(21):2698-710. doi: 10.1038/onc.2015.335. Epub 2015 Sep 21.

21.

MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo.

Sheikh BN, Downer NL, Phipson B, Vanyai HK, Kueh AJ, McCarthy DJ, Smyth GK, Thomas T, Voss AK.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5437-42. doi: 10.1073/pnas.1422872112. Epub 2015 Apr 14.

22.

Mesodermal expression of Moz is necessary for cardiac septum development.

Vanyai HK, Thomas T, Voss AK.

Dev Biol. 2015 Jul 1;403(1):22-9. doi: 10.1016/j.ydbio.2015.04.011. Epub 2015 Apr 23.

23.

The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.

Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, Tønnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP.

Nat Commun. 2015 Mar 17;6:6535. doi: 10.1038/ncomms7535.

24.

MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway.

Sheikh BN, Phipson B, El-Saafin F, Vanyai HK, Downer NL, Bird MJ, Kueh AJ, May RE, Smyth GK, Voss AK, Thomas T.

Oncogene. 2015 Nov 19;34(47):5807-20. doi: 10.1038/onc.2015.33. Epub 2015 Mar 16.

PMID:
25772242
25.

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.

Sheikh BN, Lee SC, El-Saafin F, Vanyai HK, Hu Y, Pang SH, Grabow S, Strasser A, Nutt SL, Alexander WS, Smyth GK, Voss AK, Thomas T.

Blood. 2015 Mar 19;125(12):1910-21. doi: 10.1182/blood-2014-08-594655. Epub 2015 Jan 20.

26.

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J.

Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03464.

27.

Excessive versus physiologically relevant levels of retinoic acid in embryonic stem cell differentiation.

Sheikh BN, Downer NL, Kueh AJ, Thomas T, Voss AK.

Stem Cells. 2014 Jun;32(6):1451-8. doi: 10.1002/stem.1604.

28.

Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ.

Good-Jacobson KL, Chen Y, Voss AK, Smyth GK, Thomas T, Tarlinton D.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9585-90. doi: 10.1073/pnas.1402485111. Epub 2014 Jun 16.

29.

Pro-apoptotic BIM is an essential initiator of physiological endothelial cell death independent of regulation by FOXO3.

Koenig MN, Naik E, Rohrbeck L, Herold MJ, Trounson E, Bouillet P, Thomas T, Voss AK, Strasser A, Coultas L.

Cell Death Differ. 2014 Nov;21(11):1687-95. doi: 10.1038/cdd.2014.90. Epub 2014 Jun 27.

30.

A new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelination.

Carpinelli MR, Voss AK, Manning MG, Perera AA, Cooray AA, Kile BT, Burt RA.

Dis Model Mech. 2014 Jun;7(6):649-57. doi: 10.1242/dmm.014605. Epub 2014 Mar 28.

31.

Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.

Puccini J, Shalini S, Voss AK, Gatei M, Wilson CH, Hiwase DK, Lavin MF, Dorstyn L, Kumar S.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19920-5. doi: 10.1073/pnas.1311947110. Epub 2013 Nov 18.

32.

Consequences of the combined loss of BOK and BAK or BOK and BAX.

Ke F, Bouillet P, Kaufmann T, Strasser A, Kerr J, Voss AK.

Cell Death Dis. 2013 Jun 6;4:e650. doi: 10.1038/cddis.2013.176.

33.

MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.

Voss AK, Vanyai HK, Collin C, Dixon MP, McLennan TJ, Sheikh BN, Scambler P, Thomas T.

Dev Cell. 2012 Sep 11;23(3):652-63. doi: 10.1016/j.devcel.2012.07.010. Epub 2012 Aug 23.

34.

Proteomic and metabolomic analyses of mitochondrial complex I-deficient mouse model generated by spontaneous B2 short interspersed nuclear element (SINE) insertion into NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) gene.

Leong DW, Komen JC, Hewitt CA, Arnaud E, McKenzie M, Phipson B, Bahlo M, Laskowski A, Kinkel SA, Davey GM, Heath WR, Voss AK, Zahedi RP, Pitt JJ, Chrast R, Sickmann A, Ryan MT, Smyth GK, Thorburn DR, Scott HS.

J Biol Chem. 2012 Jun 8;287(24):20652-63. doi: 10.1074/jbc.M111.327601. Epub 2012 Apr 25.

35.
36.

Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells.

Sheikh BN, Dixon MP, Thomas T, Voss AK.

J Cell Sci. 2012 Jan 15;125(Pt 2):295-309. doi: 10.1242/jcs.077271. Epub 2012 Feb 13.

37.

IAPs limit activation of RIP kinases by TNF receptor 1 during development.

Moulin M, Anderton H, Voss AK, Thomas T, Wong WW, Bankovacki A, Feltham R, Chau D, Cook WD, Silke J, Vaux DL.

EMBO J. 2012 Apr 4;31(7):1679-91. doi: 10.1038/emboj.2012.18. Epub 2012 Feb 10.

38.

Chromatin immunoprecipitation of mouse embryos.

Voss AK, Dixon MP, McLennan T, Kueh AJ, Thomas T.

Methods Mol Biol. 2012;809:335-52. doi: 10.1007/978-1-61779-376-9_23.

PMID:
22113287
39.

Whole-exome-sequencing identifies mutations in histone acetyltransferase gene KAT6B in individuals with the Say-Barber-Biesecker variant of Ohdo syndrome.

Clayton-Smith J, O'Sullivan J, Daly S, Bhaskar S, Day R, Anderson B, Voss AK, Thomas T, Biesecker LG, Smith P, Fryer A, Chandler KE, Kerr B, Tassabehji M, Lynch SA, Krajewska-Walasek M, McKee S, Smith J, Sweeney E, Mansour S, Mohammed S, Donnai D, Black G.

Am J Hum Genet. 2011 Nov 11;89(5):675-81. doi: 10.1016/j.ajhg.2011.10.008.

40.

Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice.

Kraft M, Cirstea IC, Voss AK, Thomas T, Goehring I, Sheikh BN, Gordon L, Scott H, Smyth GK, Ahmadian MR, Trautmann U, Zenker M, Tartaglia M, Ekici A, Reis A, Dörr HG, Rauch A, Thiel CT.

J Clin Invest. 2011 Sep;121(9):3479-91. doi: 10.1172/JCI43428. Epub 2011 Aug 1.

41.

Respiratory distress and perinatal lethality in Nedd4-2-deficient mice.

Boase NA, Rychkov GY, Townley SL, Dinudom A, Candi E, Voss AK, Tsoutsman T, Semsarian C, Melino G, Koentgen F, Cook DI, Kumar S.

Nat Commun. 2011;2:287. doi: 10.1038/ncomms1284.

42.

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification.

Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson TA, Collin C, Thomas T, Voss AK, Kile BT, Alexander WS, Pimanda JE, Hilton DJ.

Genes Dev. 2011 Feb 1;25(3):251-62. doi: 10.1101/gad.2009211. Epub 2011 Jan 18.

43.

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

Kueh AJ, Dixon MP, Voss AK, Thomas T.

Mol Cell Biol. 2011 Feb;31(4):845-60. doi: 10.1128/MCB.00159-10. Epub 2010 Dec 13.

44.

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.

Hewitt CA, Ling KH, Merson TD, Simpson KM, Ritchie ME, King SL, Pritchard MA, Smyth GK, Thomas T, Scott HS, Voss AK.

PLoS One. 2010 Jul 16;5(7):e11561. doi: 10.1371/journal.pone.0011561.

45.

Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity.

Voss AK, Collin C, Dixon MP, Thomas T.

Dev Cell. 2009 Nov;17(5):674-86. doi: 10.1016/j.devcel.2009.10.006.

46.

MYST family histone acetyltransferases take center stage in stem cells and development.

Voss AK, Thomas T.

Bioessays. 2009 Oct;31(10):1050-61. doi: 10.1002/bies.200900051. Review.

PMID:
19722182
47.

NHS-A isoform of the NHS gene is a novel interactor of ZO-1.

Sharma S, Koh KS, Collin C, Dave A, McMellon A, Sugiyama Y, McAvoy JW, Voss AK, Gécz J, Craig JE.

Exp Cell Res. 2009 Aug 15;315(14):2358-72. doi: 10.1016/j.yexcr.2009.05.008. Epub 2009 May 15.

PMID:
19447104
48.

Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.

Thomas T, Dixon MP, Kueh AJ, Voss AK.

Mol Cell Biol. 2008 Aug;28(16):5093-105. doi: 10.1128/MCB.02202-07. Epub 2008 Jun 9.

49.

C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment.

Voss AK, Britto JM, Dixon MP, Sheikh BN, Collin C, Tan SS, Thomas T.

Development. 2008 Jun;135(12):2139-49. doi: 10.1242/dev.016725.

50.

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells.

Loughran SJ, Kruse EA, Hacking DF, de Graaf CA, Hyland CD, Willson TA, Henley KJ, Ellis S, Voss AK, Metcalf D, Hilton DJ, Alexander WS, Kile BT.

Nat Immunol. 2008 Jul;9(7):810-9. doi: 10.1038/ni.1617. Epub 2008 May 25.

PMID:
18500345

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