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The effectiveness of an emotion-focused educational programme in reducing diabetes distress in adults with type 2 diabetes mellitus at 12-month follow-up: a cluster randomized controlled trial.

Chew BH, Vos RC, Fernandez A, Shariff Ghazali S, Shamsuddin NH, Ismail M, Rutten GEHM.

Ther Adv Endocrinol Metab. 2019 May 31;10:2042018819853761. doi: 10.1177/2042018819853761. eCollection 2019.


Metabolomics of Thrips Resistance in Pepper (Capsicum spp.) Reveals Monomer and Dimer Acyclic Diterpene Glycosides as Potential Chemical Defenses.

Macel M, Visschers IGS, Peters JL, Kappers IF, de Vos RCH, van Dam NM.

J Chem Ecol. 2019 Jun;45(5-6):490-501. doi: 10.1007/s10886-019-01074-4. Epub 2019 Jun 8.


Light-Induced Vitamin C Accumulation in Tomato Fruits is Independent of Carbohydrate Availability.

Ntagkas N, Woltering E, Bouras S, de Vos RC, Dieleman JA, Nicole CC, Labrie C, Marcelis LF.

Plants (Basel). 2019 Apr 3;8(4). pii: E86. doi: 10.3390/plants8040086.


A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters.

Witjes L, Kooke R, van der Hooft JJJ, de Vos RCH, Keurentjes JJB, Medema MH, Nijveen H.

BMC Res Notes. 2019 Apr 2;12(1):194. doi: 10.1186/s13104-019-4222-3.


Pyrethric acid of natural pyrethrin insecticide: complete pathway elucidation and reconstitution in Nicotiana benthamiana.

Xu H, Li W, Schilmiller AL, van Eekelen H, de Vos RCH, Jongsma MA, Pichersky E.

New Phytol. 2019 Mar 28. doi: 10.1111/nph.15821. [Epub ahead of print]


Association between vitamin content, plant morphology and geographical origin in a worldwide collection of the orphan crop Gynandropsis gynandra (Cleomaceae).

Sogbohossou EOD, Kortekaas D, Achigan-Dako EG, Maundu P, Stoilova T, Van Deynze A, de Vos RCH, Schranz ME.

Planta. 2019 Mar 25. doi: 10.1007/s00425-019-03142-1. [Epub ahead of print]


The effect of isolation methods of tomato pollen on the results of metabolic profiling.

Paupière MJ, Tikunov YM, Firon N, de Vos RCH, Maliepaard C, Visser RGF, Bovy AG.

Metabolomics. 2019 Jan 8;15(1):11. doi: 10.1007/s11306-018-1471-4.


Metabolite variation in the lettuce gene pool: towards healthier crop varieties and food.

van Treuren R, van Eekelen HDLM, Wehrens R, de Vos RCH.

Metabolomics. 2018 Oct 29;14(11):146. doi: 10.1007/s11306-018-1443-8.


Theory-based diabetes self-management education with pre-selection of participants: a randomized controlled trial with 2.5 years' follow-up (ELDES Study).

Vos RC, van Heusden L, Eikelenboom NWD, Rutten GEHM.

Diabet Med. 2019 Jul;36(7):827-835. doi: 10.1111/dme.13907. Epub 2019 Feb 15.


Epigenetic mapping of the Arabidopsis metabolome reveals mediators of the epigenotype-phenotype map.

Kooke R, Morgado L, Becker F, van Eekelen H, Hazarika R, Zheng Q, de Vos RCH, Johannes F, Keurentjes JJB.

Genome Res. 2019 Jan;29(1):96-106. doi: 10.1101/gr.232371.117. Epub 2018 Nov 30.


Cluster randomised trial on the effectiveness of a computerised prompt to refer (back) patients with type 2 diabetes.

Ronda MCM, Dijkhorst-Oei LT, Vos RC, Westers P, Rutten GEHM.

PLoS One. 2018 Dec 5;13(12):e0207653. doi: 10.1371/journal.pone.0207653. eCollection 2018.


A simple to implement and low-cost supervised walking programme in highly motivated individuals with or at risk for type 2 diabetes: An observational study with a pre-post design.

Hoogendoorn SW, Rutten GEHM, Hart HE, de Wolf C, Vos RC.

Prev Med Rep. 2018 Nov 7;13:30-36. doi: 10.1016/j.pmedr.2018.11.003. eCollection 2019 Mar.


QTL mapping of insect resistance components of Solanum galapagense.

Vosman B, Kashaninia A, Van't Westende W, Meijer-Dekens F, van Eekelen H, Visser RGF, de Vos RCH, Voorrips RE.

Theor Appl Genet. 2019 Feb;132(2):531-541. doi: 10.1007/s00122-018-3239-7. Epub 2018 Nov 23.


Kauniolide synthase is a P450 with unusual hydroxylation and cyclization-elimination activity.

Liu Q, Beyraghdar Kashkooli A, Manzano D, Pateraki I, Richard L, Kolkman P, Lucas MF, Guallar V, de Vos RCH, Franssen MCR, van der Krol A, Bouwmeester H.

Nat Commun. 2018 Nov 7;9(1):4657. doi: 10.1038/s41467-018-06565-8.


Laser Ablation Electrospray Ionization-Mass Spectrometry Imaging (LAESI-MS) for Spatially Resolved Plant Metabolomics.

Etalo DW, Díez-Simón C, de Vos RCH, Hall RD.

Methods Mol Biol. 2018;1778:253-267. doi: 10.1007/978-1-4939-7819-9_18.


The effectiveness of an emotion-focused educational programme in reducing diabetes distress in adults with Type 2 diabetes mellitus (VEMOFIT): a cluster randomized controlled trial.

Chew BH, Vos RC, Stellato RK, Ismail M, Rutten GEHM.

Diabet Med. 2018 Jun;35(6):750-759. doi: 10.1111/dme.13615. Epub 2018 Mar 30.


Disentangling the effect of illness perceptions on health status in people with type 2 diabetes after an acute coronary event.

Vos RC, Kasteleyn MJ, Heijmans MJ, de Leeuw E, Schellevis FG, Rijken M, Rutten GE; Diacourse study group.

BMC Fam Pract. 2018 Mar 2;19(1):35. doi: 10.1186/s12875-018-0720-y.


Broad spectrum insect resistance and metabolites in close relatives of the cultivated tomato.

Vosman B, Van't Westende WPC, Henken B, van Eekelen HDLM, de Vos RCH, Voorrips RE.

Euphytica. 2018;214(3):46. doi: 10.1007/s10681-018-2124-4. Epub 2018 Feb 6.


Metabolic responses of Eucalyptus species to different temperature regimes.

Mokochinski JB, Mazzafera P, Sawaya ACHF, Mumm R, de Vos RCH, Hall RD.

J Integr Plant Biol. 2018 May;60(5):397-411. doi: 10.1111/jipb.12626. Epub 2018 Feb 9.


Overtreatment of older patients with type 2 diabetes mellitus in primary care.

Hart HE, Rutten GE, Bontje KN, Vos RC.

Diabetes Obes Metab. 2018 Apr;20(4):1066-1069. doi: 10.1111/dom.13174. Epub 2018 Jan 24.


Oral Hypoglycemic Agents Added to Insulin Monotherapy for Type 2 Diabetes.

Vos RC, Rutten GEHM.

JAMA. 2017 Oct 17;318(15):1489-1490. doi: 10.1001/jama.2017.13463.


Psychological interventions for diabetes-related distress in adults with type 2 diabetes mellitus.

Chew BH, Vos RC, Metzendorf MI, Scholten RJ, Rutten GE.

Cochrane Database Syst Rev. 2017 Sep 27;9:CD011469. doi: 10.1002/14651858.CD011469.pub2. Review.


Validity and reliability of a Malay version of the brief illness perception questionnaire for patients with type 2 diabetes mellitus.

Chew BH, Vos RC, Heijmans M, Shariff-Ghazali S, Fernandez A, Rutten GEHM.

BMC Med Res Methodol. 2017 Aug 3;17(1):118. doi: 10.1186/s12874-017-0394-5.


What determines treatment satisfaction of patients with type 2 diabetes on insulin therapy? An observational study in eight European countries.

Boels AM, Vos RC, Hermans TGT, Zuithoff NPA, Müller N, Khunti K, Rutten GEHM; GUIDANCE study group.

BMJ Open. 2017 Jul 11;7(7):e016180. doi: 10.1136/bmjopen-2017-016180.


Effectiveness of shared goal setting and decision making to achieve treatment targets in type 2 diabetes patients: A cluster-randomized trial (OPTIMAL).

Den Ouden H, Vos RC, Rutten GEHM.

Health Expect. 2017 Oct;20(5):1172-1180. doi: 10.1111/hex.12563. Epub 2017 May 24.


The effectiveness of a value-based EMOtion-cognition-Focused educatIonal programme to reduce diabetes-related distress in Malay adults with Type 2 diabetes (VEMOFIT): study protocol for a cluster randomised controlled trial.

Chew BH, Vos RC, Shariff Ghazali S, Shamsuddin NH, Fernandez A, Mukhtar F, Ismail M, Mohd Ahad A, Sundram NN, Ali SZ, Rutten GE.

BMC Endocr Disord. 2017 Apr 4;17(1):22. doi: 10.1186/s12902-017-0172-8.


Internet-based Self-Management Support for Patients With Well-Controlled Type 2 Diabetes: A Real-Life Study.

Hart HE, Geilen IE, de Leeuw E, Rutten GE, Vos RC.

JMIR Res Protoc. 2017 Mar 23;6(3):e47. doi: 10.2196/resprot.6910.


Diabetes self-management education after pre-selection of patients: design of a randomised controlled trial.

Vos RC, Eikelenboom NW, Klomp M, Stellato RK, Rutten GE.

Diabetol Metab Syndr. 2016 Dec 20;8:82. doi: 10.1186/s13098-016-0199-4. eCollection 2016.


Arabidopsis myrosinases link the glucosinolate-myrosinase system and the cuticle.

Ahuja I, de Vos RC, Rohloff J, Stoopen GM, Halle KK, Ahmad SJ, Hoang L, Hall RD, Bones AM.

Sci Rep. 2016 Dec 15;6:38990. doi: 10.1038/srep38990.


Insulin monotherapy compared with the addition of oral glucose-lowering agents to insulin for people with type 2 diabetes already on insulin therapy and inadequate glycaemic control.

Vos RC, van Avendonk MJ, Jansen H, Goudswaard AN, van den Donk M, Gorter K, Kerssen A, Rutten GE.

Cochrane Database Syst Rev. 2016 Sep 18;9:CD006992. doi: 10.1002/14651858.CD006992.pub2. Review.


Personalised treatment targets in type 2 diabetes patients: The Dutch approach.

Boels AM, Hart HE, Rutten GE, Vos RC.

Prim Care Diabetes. 2017 Feb;11(1):71-77. doi: 10.1016/j.pcd.2016.08.001. Epub 2016 Sep 13.


Metabolomics meets functional assays: coupling LC-MS and microfluidic cell-based receptor-ligand analyses.

Henquet MGL, Roelse M, de Vos RCH, Schipper A, Polder G, de Ruijter NCA, Hall RD, Jongsma MA.

Metabolomics. 2016;12:115. doi: 10.1007/s11306-016-1057-y. Epub 2016 Jun 22.


Chemical composition and anti-inflammatory activity of the leaves of Byrsonima verbascifolia.

Saldanha AA, do Carmo LF, do Nascimento SB, de Matos NA, de Carvalho Veloso C, Castro AH, De Vos RC, Klein A, de Siqueira JM, Carollo CA, do Nascimento TV, Toffoli-Kadri MC, Soares AC.

J Nat Med. 2016 Oct;70(4):760-8. doi: 10.1007/s11418-016-1011-3. Epub 2016 Jun 8.


Differences in clinical characteristics between patients with and without type 2 diabetes hospitalized with a first myocardial infarction.

Kasteleyn MJ, Vos RC, Jansen H, Rutten GE.

J Diabetes Complications. 2016 Jul;30(5):830-3. doi: 10.1016/j.jdiacomp.2016.03.024. Epub 2016 Mar 21.


Longitudinal Association Between Gross Motor Capacity and Neuromusculoskeletal Function in Children and Youth With Cerebral Palsy.

Vos RC, Becher JG, Voorman JM, Gorter JW, van Eck M, van Meeteren J, Smits DW, Twisk JW, Dallmeijer AJ; PERRIN+ Study Group.

Arch Phys Med Rehabil. 2016 Aug;97(8):1329-37. doi: 10.1016/j.apmr.2016.03.012. Epub 2016 Apr 13.


Improved batch correction in untargeted MS-based metabolomics.

Wehrens R, Hageman JA, van Eeuwijk F, Kooke R, Flood PJ, Wijnker E, Keurentjes JJ, Lommen A, van Eekelen HD, Hall RD, Mumm R, de Vos RC.

Metabolomics. 2016;12:88. Epub 2016 Mar 18.


Efficacy of three therapy approaches in preschool children with cerebral palsy: a randomized controlled trial.

Kruijsen-Terpstra AJA, Ketelaar M, Verschuren O, Gorter JW, Vos RC, Verheijden J, Jongmans MJ, Visser-Meily A.

Dev Med Child Neurol. 2016 Jul;58(7):758-766. doi: 10.1111/dmcn.12966. Epub 2015 Nov 24.


Multi-platform metabolomics analyses of a broad collection of fragrant and non-fragrant rice varieties reveals the high complexity of grain quality characteristics.

Mumm R, Hageman JA, Calingacion MN, de Vos RCH, Jonker HH, Erban A, Kopka J, Hansen TH, Laursen KH, Schjoerring JK, Ward JL, Beale MH, Jongee S, Rauf A, Habibi F, Indrasari SD, Sakhan S, Ramli A, Romero M, Reinke RF, Ohtsubo K, Boualaphanh C, Fitzgerald MA, Hall RD.

Metabolomics. 2016;12:38. doi: 10.1007/s11306-015-0925-1. Epub 2016 Jan 23.


Spatially Resolved Plant Metabolomics: Some Potentials and Limitations of Laser-Ablation Electrospray Ionization Mass Spectrometry Metabolite Imaging.

Etalo DW, De Vos RC, Joosten MH, Hall RD.

Plant Physiol. 2015 Nov;169(3):1424-35. doi: 10.1104/pp.15.01176. Epub 2015 Sep 21.


Effectiveness of tailored support for people with Type 2 diabetes after a first acute coronary event: a multicentre randomized controlled trial (the Diacourse-ACE study).

Kasteleyn MJ, Vos RC, Rijken M, Schellevis FG, Rutten GE.

Diabet Med. 2016 Jan;33(1):125-33. doi: 10.1111/dme.12816. Epub 2015 Jun 22.


Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae: Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis.

Božić D, Papaefthimiou D, Brückner K, de Vos RC, Tsoleridis CA, Katsarou D, Papanikolaou A, Pateraki I, Chatzopoulou FM, Dimitriadou E, Kostas S, Manzano D, Scheler U, Ferrer A, Tissier A, Makris AM, Kampranis SC, Kanellis AK.

PLoS One. 2015 May 28;10(5):e0124106. doi: 10.1371/journal.pone.0124106. eCollection 2015.


Diabetes-related distress over the course of illness: results from the Diacourse study.

Kasteleyn MJ, de Vries L, van Puffelen AL, Schellevis FG, Rijken M, Vos RC, Rutten GE; Diacourse study group.

Diabet Med. 2015 Dec;32(12):1617-24. doi: 10.1111/dme.12743. Epub 2015 Mar 28.


Control of anthocyanin and non-flavonoid compounds by anthocyanin-regulating MYB and bHLH transcription factors in Nicotiana benthamiana leaves.

Outchkourov NS, Carollo CA, Gomez-Roldan V, de Vos RC, Bosch D, Hall RD, Beekwilder J.

Front Plant Sci. 2014 Oct 8;5:519. doi: 10.3389/fpls.2014.00519. eCollection 2014.


Regulatory network of secondary metabolism in Brassica rapa: insight into the glucosinolate pathway.

Pino Del Carpio D, Basnet RK, Arends D, Lin K, De Vos RC, Muth D, Kodde J, Boutilier K, Bucher J, Wang X, Jansen R, Bonnema G.

PLoS One. 2014 Sep 15;9(9):e107123. doi: 10.1371/journal.pone.0107123. eCollection 2014.


Comprehensive metabolomics to evaluate the impact of industrial processing on the phytochemical composition of vegetable purees.

Lopez-Sanchez P, de Vos RC, Jonker HH, Mumm R, Hall RD, Bialek L, Leenman R, Strassburg K, Vreeken R, Hankemeier T, Schumm S, van Duynhoven J.

Food Chem. 2015 Feb 1;168:348-55. doi: 10.1016/j.foodchem.2014.07.076. Epub 2014 Jul 24.


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