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Items: 1 to 50 of 287

1.

Deltamethrin exposure daily from postnatal day 3-20 in Sprague-Dawley rats causes long-term cognitive and behavioral deficits.

Pitzer EM, Sugimoto C, Gudelsky GA, Huff Adams CL, Williams MT, Vorhees CV.

Toxicol Sci. 2019 Mar 8. pii: kfz067. doi: 10.1093/toxsci/kfz067. [Epub ahead of print]

PMID:
30850843
2.

Metal bashing: iron deficiency and manganese overexposure impact on peripheral nerves.

Amos-Kroohs RM, Usach V, Piñero G, Vorhees CV, Martinez Vivot R, Soto PA, Williams MT, Setton-Avruj P.

J Toxicol Environ Health A. 2019;82(2):99-112. doi: 10.1080/15287394.2019.1566105. Epub 2019 Jan 17.

PMID:
30652531
3.

Effects of Preweaning Manganese in Combination with Adult Striatal Dopamine Lesions on Monoamines, BDNF, TrkB, and Cognitive Function in Sprague-Dawley Rats.

Bailey RA, Gutierrez A, Kyser TL, Hemmerle AM, Hufgard JR, Seroogy KB, Vorhees CV, Williams MT.

Neurotox Res. 2019 Apr;35(3):606-620. doi: 10.1007/s12640-018-9992-1. Epub 2019 Jan 5.

PMID:
30612279
4.

Prenatal exposure to PCBs in Cyp1a2 knock-out mice interferes with F1 fertility, impairs long-term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects.

Hufgard JR, Sprowles JLN, Pitzer EM, Koch SE, Jiang M, Wang Q, Zhang X, Biesiada J, Rubinstein J, Puga A, Williams MT, Vorhees CV.

J Appl Toxicol. 2019 Apr;39(4):603-621. doi: 10.1002/jat.3751. Epub 2018 Dec 18.

PMID:
30561030
5.

A Test of Dietary Monosodium Glutamate Developmental Neurotoxicity in Rats: A Reappraisal.

Vorhees CV.

Ann Nutr Metab. 2018;73 Suppl 5:36-42. doi: 10.1159/000494781. Epub 2018 Dec 3. Review.

6.

Introduction and Summary of the 2018 Dietary Glutamate Workshop.

Cynober L, Fernstrom JD, Koletzko B, Rietjens IMCM, Roberts A, Tennant DR, Tomé D, Vorhees CV.

Ann Nutr Metab. 2018;73 Suppl 5:1-4. doi: 10.1159/000494775. Epub 2018 Dec 3.

7.
8.

Effects of Acute Exposure of Permethrin in Adult and Developing Sprague-Dawley Rats on Acoustic Startle Response and Brain and Plasma Concentrations.

Williams MT, Gutierrez A, Vorhees CV.

Toxicol Sci. 2018 Oct 1;165(2):361-371. doi: 10.1093/toxsci/kfy142.

PMID:
29893952
9.

Developmental manganese, lead, and barren cage exposure have adverse long-term neurocognitive, behavioral and monoamine effects in Sprague-Dawley rats.

Sprowles JLN, Amos-Kroohs RM, Braun AA, Sugimoto C, Vorhees CV, Williams MT.

Neurotoxicol Teratol. 2018 May - Jun;67:50-64. doi: 10.1016/j.ntt.2018.04.001. Epub 2018 Apr 7.

PMID:
29631003
10.

A better approach to in vivo developmental neurotoxicity assessment: Alignment of rodent testing with effects seen in children after neurotoxic exposures.

Vorhees CV, Sprowles JN, Regan SL, Williams MT.

Toxicol Appl Pharmacol. 2018 Sep 1;354:176-190. doi: 10.1016/j.taap.2018.03.012. Epub 2018 Mar 12.

PMID:
29544898
11.

A Single High Dose of Methamphetamine Reduces Monoamines and Impairs Egocentric and Allocentric Learning and Memory in Adult Male Rats.

Gutierrez A, Williams MT, Vorhees CV.

Neurotox Res. 2018 Apr;33(3):671-680. doi: 10.1007/s12640-018-9871-9. Epub 2018 Feb 9.

PMID:
29427284
12.

Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8.

Udobi KC, Kokenge AN, Hautman ER, Ullio G, Coene J, Williams MT, Vorhees CV, Mabondzo A, Skelton MR.

Genes Brain Behav. 2018 Jul;17(6):e12461. doi: 10.1111/gbb.12461. Epub 2018 Feb 20.

PMID:
29384270
13.

Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes.

Kuerbitz J, Arnett M, Ehrman S, Williams MT, Vorhees CV, Fisher SE, Garratt AN, Muglia LJ, Waclaw RR, Campbell K.

J Neurosci. 2018 Jan 31;38(5):1160-1177. doi: 10.1523/JNEUROSCI.1412-17.2017. Epub 2017 Dec 18.

14.

Learning and memory effects of neonatal methamphetamine exposure in rats: Role of reactive oxygen species and age at assessment.

Jablonski SA, Williams MT, Vorhees CV.

Synapse. 2017 Nov;71(11). doi: 10.1002/syn.21992. Epub 2017 Jul 26.

PMID:
28686793
15.

Differential effects of perinatal exposure to antidepressants on learning and memory, acoustic startle, anxiety, and open-field activity in Sprague-Dawley rats.

Sprowles JLN, Hufgard JR, Gutierrez A, Bailey RA, Jablonski SA, Williams MT, Vorhees CV.

Int J Dev Neurosci. 2017 Oct;61:92-111. doi: 10.1016/j.ijdevneu.2017.06.004. Epub 2017 Jun 24.

PMID:
28655626
16.

Brain uptake of deltamethrin in rats as a function of plasma protein binding and blood-brain barrier maturation.

Amaraneni M, Pang J, Mortuza TB, Muralidhara S, Cummings BS, White CA, Vorhees CV, Zastre J, Bruckner JV.

Neurotoxicology. 2017 Sep;62:24-29. doi: 10.1016/j.neuro.2017.04.009. Epub 2017 May 8.

PMID:
28495520
17.

Phosphodiesterase-1b deletion confers depression-like behavioral resistance separate from stress-related effects in mice.

Hufgard JR, Williams MT, Vorhees CV.

Genes Brain Behav. 2017 Nov;16(8):756-767. doi: 10.1111/gbb.12391. Epub 2017 Jun 7.

18.

Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior.

López-Juárez A, Titus HE, Silbak SH, Pressler JW, Rizvi TA, Bogard M, Bennett MR, Ciraolo G, Williams MT, Vorhees CV, Ratner N.

Cell Rep. 2017 Apr 18;19(3):545-557. doi: 10.1016/j.celrep.2017.03.073.

19.

Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a.

Hufgard JR, Williams MT, Skelton MR, Grubisha O, Ferreira FM, Sanger H, Wright ME, Reed-Kessler TM, Rasmussen K, Duman RS, Vorhees CV.

Psychopharmacology (Berl). 2017 Jun;234(12):1803-1813. doi: 10.1007/s00213-017-4587-8. Epub 2017 Mar 23.

PMID:
28337525
20.

Effects of Housing on Methamphetamine-Induced Neurotoxicity and Spatial Learning and Memory.

Gutierrez A, Jablonski SA, Amos-Kroohs RM, Barnes AC, Williams MT, Vorhees CV.

ACS Chem Neurosci. 2017 Jul 19;8(7):1479-1489. doi: 10.1021/acschemneuro.6b00419. Epub 2017 Mar 27.

PMID:
28287691
21.
22.

Effects of Neonatal Methamphetamine and Stress on Brain Monoamines and Corticosterone in Preweanling Rats.

Jablonski SA, Graham DL, Vorhees CV, Williams MT.

Neurotox Res. 2017 Feb;31(2):269-282. doi: 10.1007/s12640-016-9680-y. Epub 2016 Nov 5.

23.

Developmental manganese neurotoxicity in rats: Cognitive deficits in allocentric and egocentric learning and memory.

Amos-Kroohs RM, Davenport LL, Atanasova N, Abdulla ZI, Skelton MR, Vorhees CV, Williams MT.

Neurotoxicol Teratol. 2017 Jan - Feb;59:16-26. doi: 10.1016/j.ntt.2016.10.005. Epub 2016 Oct 15.

24.

A heterozygous mutation in tubulin, beta 2B ( Tubb2b ) causes cognitive deficits and hippocampal disorganization.

Stottmann RW, Driver A, Gutierrez A, Skelton MR, Muntifering M, Stepien C, Knudson L, Kofron M, Vorhees CV, Williams MT.

Genes Brain Behav. 2017 Feb;16(2):250-259. doi: 10.1111/gbb.12327. Epub 2016 Oct 3.

25.

Perinatal exposure to the selective serotonin reuptake inhibitor citalopram alters spatial learning and memory, anxiety, depression, and startle in Sprague-Dawley rats.

Sprowles JL, Hufgard JR, Gutierrez A, Bailey RA, Jablonski SA, Williams MT, Vorhees CV.

Int J Dev Neurosci. 2016 Nov;54:39-52. doi: 10.1016/j.ijdevneu.2016.08.007. Epub 2016 Aug 31.

PMID:
27591973
26.

Cincinnati water maze: A review of the development, methods, and evidence as a test of egocentric learning and memory.

Vorhees CV, Williams MT.

Neurotoxicol Teratol. 2016 Sep - Oct;57:1-19. doi: 10.1016/j.ntt.2016.08.002. Epub 2016 Aug 18. Review.

27.

Developmental manganese exposure in combination with developmental stress and iron deficiency: Effects on behavior and monoamines.

Amos-Kroohs RM, Davenport LL, Gutierrez A, Hufgard JR, Vorhees CV, Williams MT.

Neurotoxicol Teratol. 2016 Jul-Aug;56:55-67. doi: 10.1016/j.ntt.2016.06.004. Epub 2016 Jun 11.

PMID:
27302314
28.

Mechanisms involved in the neurotoxic and cognitive effects of developmental methamphetamine exposure.

Jablonski SA, Williams MT, Vorhees CV.

Birth Defects Res C Embryo Today. 2016 Jun;108(2):131-41. doi: 10.1002/bdrc.21130. Epub 2016 Jun 13. Review.

PMID:
27297291
29.

6-Hydroxydopamine-Induced Dopamine Reductions in the Nucleus Accumbens, but not the Medial Prefrontal Cortex, Impair Cincinnati Water Maze Egocentric and Morris Water Maze Allocentric Navigation in Male Sprague-Dawley Rats.

Braun AA, Amos-Kroohs RM, Gutierrez A, Lundgren KH, Seroogy KB, Vorhees CV, Williams MT.

Neurotox Res. 2016 Aug;30(2):199-212. doi: 10.1007/s12640-016-9616-6. Epub 2016 Mar 22.

PMID:
27003940
30.

Developmental stress and lead (Pb): Effects of maternal separation and/or Pb on corticosterone, monoamines, and blood Pb in rats.

Amos-Kroohs RM, Graham DL, Grace CE, Braun AA, Schaefer TL, Skelton MR, Vorhees CV, Williams MT.

Neurotoxicology. 2016 May;54:22-33. doi: 10.1016/j.neuro.2016.02.011. Epub 2016 Mar 2.

31.

Assessment of learning, memory, and attention in developmental neurotoxicity regulatory studies: synthesis, commentary, and recommendations.

Vorhees CV, Makris SL.

Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt A):109-15. doi: 10.1016/j.ntt.2015.10.004. Epub 2015 Oct 23.

PMID:
26526903
32.

Neurobehavioral Effects from Developmental Methamphetamine Exposure.

Jablonski SA, Williams MT, Vorhees CV.

Curr Top Behav Neurosci. 2016;29:183-230. doi: 10.1007/7854_2015_405. Review.

PMID:
26520437
33.

Modulation of Polycystic Kidney Disease Severity by Phosphodiesterase 1 and 3 Subfamilies.

Ye H, Wang X, Sussman CR, Hopp K, Irazabal MV, Bakeberg JL, LaRiviere WB, Manganiello VC, Vorhees CV, Zhao H, Harris PC, van Deursen J, Ward CJ, Torres VE.

J Am Soc Nephrol. 2016 May;27(5):1312-20. doi: 10.1681/ASN.2015010057. Epub 2015 Sep 15.

34.

Systemic and behavioral effects of intranasal administration of silver nanoparticles.

Davenport LL, Hsieh H, Eppert BL, Carreira VS, Krishan M, Ingle T, Howard PC, Williams MT, Vorhees CV, Genter MB.

Neurotoxicol Teratol. 2015 Sep-Oct;51:68-76. doi: 10.1016/j.ntt.2015.08.006. Epub 2015 Sep 2.

36.

Reprint of "Value of water mazes for assessing spatial and egocentric learning and memory in rodent basic research and regulatory studies".

Vorhees CV, Williams MT.

Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt A):93-108. doi: 10.1016/j.ntt.2015.06.002. Epub 2015 Jun 9.

PMID:
26071087
37.

Assessment of learning, memory and attention in developmental neurotoxicity regulatory studies: Introduction.

Makris SL, Vorhees CV.

Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt A):62-7. doi: 10.1016/j.ntt.2015.05.010. Epub 2015 Jun 3.

PMID:
26049062
38.

Chronic social defeat, but not restraint stress, alters bladder function in mice.

Mann EA, Alam Z, Hufgard JR, Mogle M, Williams MT, Vorhees CV, Reddy P.

Physiol Behav. 2015 Oct 15;150:83-92. doi: 10.1016/j.physbeh.2015.02.021. Epub 2015 Feb 15.

39.

Effects of developmental manganese, stress, and the combination of both on monoamines, growth, and corticosterone.

Vorhees CV, Graham DL, Amos-Kroohs RM, Braun AA, Grace CE, Schaefer TL, Skelton MR, Erikson KM, Aschner M, Williams MT.

Toxicol Rep. 2014;1:1046-1061.

40.

Dopamine depletion in either the dorsomedial or dorsolateral striatum impairs egocentric Cincinnati water maze performance while sparing allocentric Morris water maze learning.

Braun AA, Amos-Kroohs RM, Gutierrez A, Lundgren KH, Seroogy KB, Skelton MR, Vorhees CV, Williams MT.

Neurobiol Learn Mem. 2015 Feb;118:55-63. doi: 10.1016/j.nlm.2014.10.009. Epub 2014 Nov 13.

41.

Prenatal immune challenge in rats: effects of polyinosinic-polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine.

Vorhees CV, Graham DL, Braun AA, Schaefer TL, Skelton MR, Richtand NM, Williams MT.

Neurotoxicol Teratol. 2015 Jan-Feb;47:54-65. doi: 10.1016/j.ntt.2014.10.007. Epub 2014 Nov 8.

42.

Neuronal reorganization in adult rats neonatally exposed to (±)-3,4-methylenedioxymethamphetamine.

Williams MT, Skelton MR, Longacre ID, Huggins KN, Maple AM, Vorhees CV, Brown RW.

Toxicol Rep. 2014;1:699-706.

43.

Assessing spatial learning and memory in rodents.

Vorhees CV, Williams MT.

ILAR J. 2014;55(2):310-32. doi: 10.1093/ilar/ilu013. Review.

44.

Value of water mazes for assessing spatial and egocentric learning and memory in rodent basic research and regulatory studies.

Vorhees CV, Williams MT.

Neurotoxicol Teratol. 2014 Sep-Oct;45:75-90. doi: 10.1016/j.ntt.2014.07.003. Epub 2014 Aug 10. Review.

PMID:
25116937
45.

A combination of mild hypothermia and sevoflurane affords long-term protection in a modified neonatal mouse model of cerebral hypoxia-ischemia.

Lin EP, Miles L, Hughes EA, McCann JC, Vorhees CV, McAuliffe JJ, Loepke AW.

Anesth Analg. 2014 Nov;119(5):1158-73. doi: 10.1213/ANE.0000000000000262.

PMID:
24878681
46.

Kaolin-induced ventriculomegaly at weaning produces long-term learning, memory, and motor deficits in rats.

Williams MT, Braun AA, Amos-Kroohs RM, McAllister JP 2nd, Lindquist DM, Mangano FT, Vorhees CV, Yuan W.

Int J Dev Neurosci. 2014 Jun;35:7-15. doi: 10.1016/j.ijdevneu.2014.02.002. Epub 2014 Mar 2.

47.

The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse.

Ehrman LA, Mu X, Waclaw RR, Yoshida Y, Vorhees CV, Klein WH, Campbell K.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4026-35. doi: 10.1073/pnas.1308275110. Epub 2013 Sep 30.

48.

Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature.

Mayes DA, Rizvi TA, Titus-Mitchell H, Oberst R, Ciraolo GM, Vorhees CV, Robinson AP, Miller SD, Cancelas JA, Stemmer-Rachamimov AO, Ratner N.

Cell Rep. 2013 Sep 26;4(6):1197-212. doi: 10.1016/j.celrep.2013.08.011. Epub 2013 Sep 12.

49.

Female mice heterozygous for creatine transporter deficiency show moderate cognitive deficits.

Hautman ER, Kokenge AN, Udobi KC, Williams MT, Vorhees CV, Skelton MR.

J Inherit Metab Dis. 2014 Jan;37(1):63-8. doi: 10.1007/s10545-013-9619-x. Epub 2013 May 29.

PMID:
23716276
50.

Tissue-specific effects of saposin A and saposin B on glycosphingolipid degradation in mutant mice.

Sun Y, Zamzow M, Ran H, Zhang W, Quinn B, Barnes S, Witte DP, Setchell KD, Williams MT, Vorhees CV, Grabowski GA.

Hum Mol Genet. 2013 Jun 15;22(12):2435-50. doi: 10.1093/hmg/ddt096. Epub 2013 Feb 27.

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