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Items: 14

1.

Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).

Kikuchi R, Lao Y, Bow DA, Chiou WJ, Andracki ME, Carr RA, Voorman RL, De Morais SM.

J Pharm Sci. 2013 Dec;102(12):4426-32. doi: 10.1002/jps.23737. Epub 2013 Oct 2.

PMID:
24122511
2.

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

Chiou WJ, de Morais SM, Kikuchi R, Voorman RL, Li X, Bow DA.

Xenobiotica. 2014 Mar;44(3):276-82. doi: 10.3109/00498254.2013.820006. Epub 2013 Jul 25.

PMID:
23886114
3.

Development of in vitro methods to predict induction of CYP1A2 and CYP3A4 in humans.

Grover GS, Brayman TG, Voorman RL, Ware JA.

Assay Drug Dev Technol. 2007 Dec;5(6):793-804.

PMID:
18052847
4.

Parabens inhibit human skin estrogen sulfotransferase activity: possible link to paraben estrogenic effects.

Prusakiewicz JJ, Harville HM, Zhang Y, Ackermann C, Voorman RL.

Toxicology. 2007 Apr 11;232(3):248-56. Epub 2007 Jan 19.

PMID:
17306434
5.

Metabolic aromatization of N-alkyl-1,2,3,4-tetrahydroquinoline substructures to quinolinium by human liver microsomes and horseradish peroxidase.

Gu C, Collins R, Holsworth DD, Walker GS, Voorman RL.

Drug Metab Dispos. 2006 Dec;34(12):2044-55. Epub 2006 Sep 19.

PMID:
16985099
6.

Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.

Voorman RL, Payne NA, Wienkers LC, Hauer MJ, Sanders PE.

Drug Metab Dispos. 2001 Jan;29(1):41-7.

PMID:
11124228
7.

Synthesis and structure-activity relationships of the (alkylamino)piperidine-containing BHAP class of non-nucleoside reverse transcriptase inhibitors: effect of 3-alkylpyridine ring substitution.

Genin MJ, Poel TJ, May PD, Kopta LA, Yagi Y, Olmsted RA, Friis JM, Voorman RL, Adams WJ, Thomas RC, Romero DL.

J Med Chem. 1999 Oct 7;42(20):4140-9.

PMID:
10514284
8.

Microsomal metabolism of delavirdine: evidence for mechanism-based inactivation of human cytochrome P450 3A.

Voorman RL, Maio SM, Payne NA, Zhao Z, Koeplinger KA, Wang X.

J Pharmacol Exp Ther. 1998 Oct;287(1):381-8.

PMID:
9765359
9.

Absorption, distribution, metabolism, and excretion of atevirdine in the rat.

Chang M, Sood VK, Wilson GJ, Kloosterman DA, Sanders PE, Schuette MR, Judy RW, Voorman RL, Maio SM, Slatter JG.

Drug Metab Dispos. 1998 Oct;26(10):1008-18.

PMID:
9763407
11.

Synthesis and bioactivity of novel bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships and increased metabolic stability of novel substituted pyridine analogs.

Genin MJ, Poel TJ, Yagi Y, Biles C, Althaus I, Keiser BJ, Kopta LA, Friis JM, Reusser F, Adams WJ, Olmsted RA, Voorman RL, Thomas RC, Romero DL.

J Med Chem. 1996 Dec 20;39(26):5267-75.

PMID:
8978855
12.

Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.

Romero DL, Olmsted RA, Poel TJ, Morge RA, Biles C, Keiser BJ, Kopta LA, Friis JM, Hosley JD, Stefanski KJ, Wishka DG, Evans DB, Morris J, Stehle RG, Sharma SK, Yagi Y, Voorman RL, Adams WJ, Tarpley WG, Thomas RC.

J Med Chem. 1996 Sep 13;39(19):3769-89.

PMID:
8809165
13.

Identification of dioxin-responsive genes in Hep G2 cells using differential mRNA display RT-PCR.

Wang X, Harris PK, Ulrich RG, Voorman RL.

Biochem Biophys Res Commun. 1996 Mar 27;220(3):784-8.

PMID:
8607842
14.

Insertion of constant region domains of human IgG1 into CD4-PE40 increases its plasma half-life.

Batra JK, Kasturi S, Gallo MG, Voorman RL, Maio SM, Chaudhary VK, Pastan I.

Mol Immunol. 1993 Mar;30(4):379-86.

PMID:
8455638

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