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Items: 26

1.

The role of lymphatic transport on the systemic bioavailability of the Bcl-2 protein family inhibitors navitoclax (ABT-263) and ABT-199.

Choo EF, Boggs J, Zhu C, Lubach JW, Catron ND, Jenkins G, Souers AJ, Voorman R.

Drug Metab Dispos. 2014 Feb;42(2):207-12. doi: 10.1124/dmd.113.055053. Epub 2013 Nov 8.

PMID:
24212376
2.

Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).

Kikuchi R, Lao Y, Bow DA, Chiou WJ, Andracki ME, Carr RA, Voorman RL, De Morais SM.

J Pharm Sci. 2013 Dec;102(12):4426-32. doi: 10.1002/jps.23737. Epub 2013 Oct 2.

PMID:
24122511
3.

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

Chiou WJ, de Morais SM, Kikuchi R, Voorman RL, Li X, Bow DA.

Xenobiotica. 2014 Mar;44(3):276-82. doi: 10.3109/00498254.2013.820006. Epub 2013 Jul 25.

PMID:
23886114
4.

Disposition and drug-drug interaction potential of veliparib (ABT-888), a novel and potent inhibitor of poly(ADP-ribose) polymerase.

Li X, Delzer J, Voorman R, de Morais SM, Lao Y.

Drug Metab Dispos. 2011 Jul;39(7):1161-9. doi: 10.1124/dmd.110.037820. Epub 2011 Mar 24.

PMID:
21436403
5.

Development of in vitro methods to predict induction of CYP1A2 and CYP3A4 in humans.

Grover GS, Brayman TG, Voorman RL, Ware JA.

Assay Drug Dev Technol. 2007 Dec;5(6):793-804.

PMID:
18052847
6.

Hydrolysis of a series of parabens by skin microsomes and cytosol from human and minipigs and in whole skin in short-term culture.

Jewell C, Prusakiewicz JJ, Ackermann C, Payne NA, Fate G, Voorman R, Williams FM.

Toxicol Appl Pharmacol. 2007 Dec 1;225(2):221-8. Epub 2007 Aug 16.

PMID:
17889094
7.

Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver.

Jewell C, Ackermann C, Payne NA, Fate G, Voorman R, Williams FM.

Drug Metab Dispos. 2007 Nov;35(11):2015-22. Epub 2007 Jul 30.

PMID:
17664252
8.

The time to move cytochrome p450 induction into mainstream pharmacology is long overdue.

Smith DA, Dickins M, Fahmi OA, Iwasaki K, Lee C, Obach RS, Padbury G, De Morais SM, Ripp SL, Stevens J, Voorman R, Youdim K.

Drug Metab Dispos. 2007 Apr;35(4):697-8. No abstract available.

PMID:
17384203
9.

Parabens inhibit human skin estrogen sulfotransferase activity: possible link to paraben estrogenic effects.

Prusakiewicz JJ, Harville HM, Zhang Y, Ackermann C, Voorman RL.

Toxicology. 2007 Apr 11;232(3):248-56. Epub 2007 Jan 19.

PMID:
17306434
10.

Comparison of paraben stability in human and rat skin.

Harville HM, Voorman R, Prusakiewicz JJ.

Drug Metab Lett. 2007 Jan;1(1):17-21.

PMID:
19356013
11.

Metabolic aromatization of N-alkyl-1,2,3,4-tetrahydroquinoline substructures to quinolinium by human liver microsomes and horseradish peroxidase.

Gu C, Collins R, Holsworth DD, Walker GS, Voorman RL.

Drug Metab Dispos. 2006 Dec;34(12):2044-55. Epub 2006 Sep 19.

PMID:
16985099
12.

Comparison of skin esterase activities from different species.

Prusakiewicz JJ, Ackermann C, Voorman R.

Pharm Res. 2006 Jul;23(7):1517-24. Epub 2006 Jun 21.

PMID:
16779705
13.

Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.

Voorman RL, Payne NA, Wienkers LC, Hauer MJ, Sanders PE.

Drug Metab Dispos. 2001 Jan;29(1):41-7.

PMID:
11124228
14.

Synthesis and structure-activity relationships of the (alkylamino)piperidine-containing BHAP class of non-nucleoside reverse transcriptase inhibitors: effect of 3-alkylpyridine ring substitution.

Genin MJ, Poel TJ, May PD, Kopta LA, Yagi Y, Olmsted RA, Friis JM, Voorman RL, Adams WJ, Thomas RC, Romero DL.

J Med Chem. 1999 Oct 7;42(20):4140-9.

PMID:
10514284
15.

Microsomal metabolism of delavirdine: evidence for mechanism-based inactivation of human cytochrome P450 3A.

Voorman RL, Maio SM, Payne NA, Zhao Z, Koeplinger KA, Wang X.

J Pharmacol Exp Ther. 1998 Oct;287(1):381-8.

PMID:
9765359
16.

Absorption, distribution, metabolism, and excretion of atevirdine in the rat.

Chang M, Sood VK, Wilson GJ, Kloosterman DA, Sanders PE, Schuette MR, Judy RW, Voorman RL, Maio SM, Slatter JG.

Drug Metab Dispos. 1998 Oct;26(10):1008-18.

PMID:
9763407
18.

Synthesis and bioactivity of novel bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships and increased metabolic stability of novel substituted pyridine analogs.

Genin MJ, Poel TJ, Yagi Y, Biles C, Althaus I, Keiser BJ, Kopta LA, Friis JM, Reusser F, Adams WJ, Olmsted RA, Voorman RL, Thomas RC, Romero DL.

J Med Chem. 1996 Dec 20;39(26):5267-75.

PMID:
8978855
19.

Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.

Romero DL, Olmsted RA, Poel TJ, Morge RA, Biles C, Keiser BJ, Kopta LA, Friis JM, Hosley JD, Stefanski KJ, Wishka DG, Evans DB, Morris J, Stehle RG, Sharma SK, Yagi Y, Voorman RL, Adams WJ, Tarpley WG, Thomas RC.

J Med Chem. 1996 Sep 13;39(19):3769-89.

PMID:
8809165
20.

Identification of dioxin-responsive genes in Hep G2 cells using differential mRNA display RT-PCR.

Wang X, Harris PK, Ulrich RG, Voorman RL.

Biochem Biophys Res Commun. 1996 Mar 27;220(3):784-8.

PMID:
8607842
21.

Insertion of constant region domains of human IgG1 into CD4-PE40 increases its plasma half-life.

Batra JK, Kasturi S, Gallo MG, Voorman RL, Maio SM, Chaudhary VK, Pastan I.

Mol Immunol. 1993 Mar;30(4):379-86.

PMID:
8455638
22.

TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) is a tight binding inhibitor of cytochrome P-450d.

Voorman R, Aust SD.

J Biochem Toxicol. 1989 Summer;4(2):105-9.

PMID:
2593129
23.
24.

Inhibition of 2-aminofluorene mutagenesis in bacteria by inducers of cytochrome P-450d.

Miller DM, Aust AE, Voorman R, Aust SD.

Carcinogenesis. 1988 Feb;9(2):327-9.

PMID:
3123085
25.

Activity of thyroid hormone-inducible enzymes following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Roth W, Voorman R, Aust SD.

Toxicol Appl Pharmacol. 1988 Jan;92(1):65-74.

PMID:
3341028

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