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Items: 1 to 50 of 144

1.

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers TW, van den Biggelaar M, Voorberg J, Bierings R.

Haematologica. 2019 Jan 10. pii: haematol.2018.207787. doi: 10.3324/haematol.2018.207787. [Epub ahead of print]

2.

Prevention of the anti-factor VIII memory B-cell response by inhibition of Bruton tyrosine kinase in experimental hemophilia A.

Delignat S, Russick J, Gangadharan B, Rayes J, Ing M, Voorberg J, Kaveri SV, Lacroix-Desmazes S.

Haematologica. 2019 May;104(5):1046-1054. doi: 10.3324/haematol.2018.200279. Epub 2018 Dec 13.

3.

Generation of anti-idiotypic antibodies to detect anti-spacer antibody idiotopes in acute thrombotic thrombocytopenic purpura patients.

Schelpe AS, Roose E, Joly BS, Pareyn I, Mancini I, Biganzoli M, Deckmyn H, Voorberg J, Fijnheer R, Peyvandi F, De Meyer SF, Coppo P, Veyradier A, Vanhoorelbeke K.

Haematologica. 2018 Dec 6. pii: haematol.2018.205666. doi: 10.3324/haematol.2018.205666. [Epub ahead of print]

4.

Antibodies against recombinant alpha-galactosidase A in Fabry disease: Subclass analysis and impact on response to treatment.

van der Veen SJ, van Kuilenburg ABP, Hollak CEM, Kaijen PHP, Voorberg J, Langeveld M.

Mol Genet Metab. 2019 Feb;126(2):162-168. doi: 10.1016/j.ymgme.2018.11.008. Epub 2018 Nov 17.

PMID:
30473480
5.

Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets.

Rijkers M, Schmidt D, Lu N, Kramer CSM, Heidt S, Mulder A, Porcelijn L, Claas FHJ, Leebeek FWG, Jansen AJG, Jongerius I, Zeerleder SS, Vidarsson G, Voorberg J, de Haas M.

Haematologica. 2019 Feb;104(2):403-416. doi: 10.3324/haematol.2018.201665. Epub 2018 Sep 27.

6.

Anti-ADAMTS13 Autoantibodies against Cryptic Epitopes in Immune-Mediated Thrombotic Thrombocytopenic Purpura.

Roose E, Vidarsson G, Kangro K, Verhagen OJHM, Mancini I, Desender L, Pareyn I, Vandeputte N, Vandenbulcke A, Vendramin C, Schelpe AS, Voorberg J, Azerad MA, Gilardin L, Scully M, Dierickx D, Deckmyn H, De Meyer SF, Peyvandi F, Vanhoorelbeke K.

Thromb Haemost. 2018 Oct;118(10):1729-1742. doi: 10.1055/s-0038-1669459. Epub 2018 Sep 20.

7.

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Schillemans M, Karampini E, van den Eshof BL, Gangaev A, Hofman M, van Breevoort D, Meems H, Janssen H, Mulder AA, Jost CR, Escher JC, Adam R, Carter T, Koster AJ, van den Biggelaar M, Voorberg J, Bierings R.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1549-1561. doi: 10.1161/ATVBAHA.117.310701. Epub 2018 Jun 7.

8.

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation.

Rijkers M, Saris A, Heidt S, Mulder A, Porcelijn L, Claas FHJ, Bierings R, Leebeek FWG, Jansen AJG, Vidarsson G, Voorberg J, de Haas M.

Haematologica. 2018 Oct;103(10):1741-1752. doi: 10.3324/haematol.2018.189365. Epub 2018 Jun 1.

9.

Emerging Concepts in Immune Thrombocytopenia.

Swinkels M, Rijkers M, Voorberg J, Vidarsson G, Leebeek FWG, Jansen AJG.

Front Immunol. 2018 Apr 30;9:880. doi: 10.3389/fimmu.2018.00880. eCollection 2018. Review.

10.

Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers.

Hrdinová J, D'Angelo S, Graça NAG, Ercig B, Vanhoorelbeke K, Veyradier A, Voorberg J, Coppo P.

Haematologica. 2018 Jul;103(7):1099-1109. doi: 10.3324/haematol.2016.151407. Epub 2018 Apr 19. Review.

11.

Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ.

Hrdinová J, Verbij FC, Kaijen PHP, Hartholt RB, van Alphen F, Lardy N, Ten Brinke A, Vanhoorelbeke K, Hindocha PJ, De Groot AS, Meijer AB, Voorberg J, Peyron I.

Haematologica. 2018 Jun;103(6):1083-1092. doi: 10.3324/haematol.2017.179119. Epub 2018 Mar 22.

12.

Correction: Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.

Smeets MWJ, Bierings R, Meems H, Mul FPJ, Geerts D, Vlaar APJ, Voorberg J, Hordijk PL.

PLoS One. 2018 Mar 21;13(3):e0194958. doi: 10.1371/journal.pone.0194958. eCollection 2018.

13.

Inhibitors in Nonsevere Hemophilia A: What Is Known and Searching for the Unknown.

Abdi A, Linari S, Pieri L, Voorberg J, Fijnvandraat K, Castaman G.

Semin Thromb Hemost. 2018 Sep;44(6):568-577. doi: 10.1055/s-0037-1621717. Epub 2018 Feb 13. Review.

PMID:
29439277
14.

Desmopressin in moderate hemophilia A patients: a treatment worth considering.

Loomans JI, Kruip MJHA, Carcao M, Jackson S, van Velzen AS, Peters M, Santagostino E, Platokouki H, Beckers E, Voorberg J, van der Bom JG, Fijnvandraat K; RISE consortium.

Haematologica. 2018 Mar;103(3):550-557. doi: 10.3324/haematol.2017.180059. Epub 2018 Jan 5.

15.

Insights into 3D Structure of ADAMTS13: A Stepping Stone towards Novel Therapeutic Treatment of Thrombotic Thrombocytopenic Purpura.

Ercig B, Wichapong K, Reutelingsperger CPM, Vanhoorelbeke K, Voorberg J, Nicolaes GAF.

Thromb Haemost. 2018 Jan;118(1):28-41. doi: 10.1160/TH17-06-0404. Epub 2018 Jan 5.

PMID:
29304523
16.

The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages.

Verbij FC, Sorvillo N, Kaijen PHP, Hrdinova J, Peyron I, Fijnheer R, Ten Brinke A, Meijer AB, van Alphen FPJ, van den Berg TK, Graversen JJH, Moestrup SK, Voorberg J.

Blood Adv. 2017 Jan 16;1(5):293-305. doi: 10.1182/bloodadvances.2016001321. eCollection 2017 Jan 24.

17.

Early cellular interactions and immune transcriptome profiles in human factor VIII-exposed hemophilia A mice.

Lai JD, Cartier D, Hartholt RB, Swystun LL, van Velzen AS, den Haan JMM, Hough C, Voorberg J, Lillicrap D.

J Thromb Haemost. 2018 Mar;16(3):533-545. doi: 10.1111/jth.13936. Epub 2018 Feb 2.

PMID:
29285874
18.

An open conformation of ADAMTS-13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura.

Roose E, Schelpe AS, Joly BS, Peetermans M, Verhamme P, Voorberg J, Greinacher A, Deckmyn H, De Meyer SF, Coppo P, Veyradier A, Vanhoorelbeke K.

J Thromb Haemost. 2018 Feb;16(2):378-388. doi: 10.1111/jth.13922. Epub 2018 Jan 23.

PMID:
29222940
19.

Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells.

Peyron I, Hartholt RB, Pedró-Cos L, van Alphen F, Brinke AT, Lardy N, Meijer AB, Voorberg J.

Haematologica. 2018 Jan;103(1):172-178. doi: 10.3324/haematol.2017.175083. Epub 2017 Oct 12.

20.

Monitoring storage induced changes in the platelet proteome employing label free quantitative mass spectrometry.

Rijkers M, van den Eshof BL, van der Meer PF, van Alphen FPJ, de Korte D, Leebeek FWG, Meijer AB, Voorberg J, Jansen AJG.

Sci Rep. 2017 Sep 8;7(1):11045. doi: 10.1038/s41598-017-11643-w.

21.

To serve and protect: The modulatory role of von Willebrand factor on factor VIII immunogenicity.

Hartholt RB, van Velzen AS, Peyron I, Ten Brinke A, Fijnvandraat K, Voorberg J.

Blood Rev. 2017 Sep;31(5):339-347. doi: 10.1016/j.blre.2017.07.001. Epub 2017 Jul 4. Review.

PMID:
28716211
22.

Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.

Smeets MW, Bierings R, Meems H, Mul FP, Geerts D, Vlaar AP, Voorberg J, Hordijk PL.

PLoS One. 2017 Mar 1;12(3):e0173077. doi: 10.1371/journal.pone.0173077. eCollection 2017. Erratum in: PLoS One. 2018 Mar 21;13(3):e0194958.

23.

Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking.

Ebberink EH, Bouwens EA, Bloem E, Boon-Spijker M, van den Biggelaar M, Voorberg J, Meijer AB, Mertens K.

Haematologica. 2017 Apr;102(4):686-694. doi: 10.3324/haematol.2016.153163. Epub 2017 Jan 5.

24.

Variation in baseline factor VIII concentration in a retrospective cohort of mild/moderate hemophilia A patients carrying identical F8 mutations.

Loomans JI, van Velzen AS, Eckhardt CL, Peters M, Mäkipernaa A, Holmstrom M, Brons PP, Dors N, Haya S, Voorberg J, van der Bom JG, Fijnvandraat K.

J Thromb Haemost. 2017 Feb;15(2):246-254. doi: 10.1111/jth.13581. Epub 2017 Feb 3.

25.

Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells.

Hartholt RB, Wroblewska A, Herczenik E, Peyron I, Ten Brinke A, Rispens T, Nolte MA, Slot E, Claassens JW, Nimmerjahn F, Verbeek JS, Voorberg J.

J Thromb Haemost. 2017 Feb;15(2):329-340. doi: 10.1111/jth.13570. Epub 2017 Jan 19.

26.

Evaluation of the role of the GPIb-IX-V receptor complex in development of the platelet storage lesion.

Rijkers M, van der Meer PF, Bontekoe IJ, Daal BB, de Korte D, Leebeek FW, Voorberg J, Jansen AJ.

Vox Sang. 2016 Oct;111(3):247-256. doi: 10.1111/vox.12416. Epub 2016 May 17.

PMID:
27184018
27.

Identification of glycans on plasma-derived ADAMTS13.

Verbij FC, Stokhuijzen E, Kaijen PH, van Alphen F, Meijer AB, Voorberg J.

Blood. 2016 Nov 24;128(21):e51-e58. Epub 2016 Aug 29.

28.

Up or out: polarity of VWF release.

Bierings R, Voorberg J.

Blood. 2016 Jul 14;128(2):154-5. doi: 10.1182/blood-2016-05-713057. No abstract available.

29.

Analysis of the HLA-DR peptidome from human dendritic cells reveals high affinity repertoires and nonconventional pathways of peptide generation.

Ciudad MT, Sorvillo N, van Alphen FP, Catalán D, Meijer AB, Voorberg J, Jaraquemada D.

J Leukoc Biol. 2017 Jan;101(1):15-27. doi: 10.1189/jlb.6HI0216-069R. Epub 2016 Jun 30.

PMID:
27365532
30.

CD4+ T cells from patients with acquired thrombotic thrombocytopenic purpura recognize CUB2 domain-derived peptides.

Verbij FC, Turksma AW, de Heij F, Kaijen P, Lardy N, Fijnheer R, Sorvillo N, ten Brinke A, Voorberg J.

Blood. 2016 Mar 24;127(12):1606-9. doi: 10.1182/blood-2015-10-668053. Epub 2016 Jan 8.

31.

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

Sorvillo N, Hartholt RB, Bloem E, Sedek M, ten Brinke A, van der Zwaan C, van Alphen FP, Meijer AB, Voorberg J.

Haematologica. 2016 Mar;101(3):309-18. doi: 10.3324/haematol.2015.137067. Epub 2015 Dec 3.

32.

Hunting down factor VIII in the immunopeptidome.

Hartholt RB, Peyron I, Voorberg J.

Cell Immunol. 2016 Mar;301:59-64. doi: 10.1016/j.cellimm.2015.11.001. Epub 2015 Nov 5. Review.

PMID:
26610639
33.

Disappearing acts of ADAMTS13.

Voorberg J, Verbij FC, Fijnheer R.

EBioMedicine. 2015 Jul 10;2(8):800-1. doi: 10.1016/j.ebiom.2015.07.013. eCollection 2015 Aug. Review. No abstract available.

34.

Angiogenic characteristics of blood outgrowth endothelial cells from patients with von Willebrand disease.

Groeneveld DJ, van Bekkum T, Dirven RJ, Wang JW, Voorberg J, Reitsma PH, Eikenboom J.

J Thromb Haemost. 2015 Oct;13(10):1854-66. doi: 10.1111/jth.13112. Epub 2015 Sep 21.

35.

Content delivery to newly forming Weibel-Palade bodies is facilitated by multiple connections with the Golgi apparatus.

Mourik MJ, Faas FG, Zimmermann H, Voorberg J, Koster AJ, Eikenboom J.

Blood. 2015 May 28;125(22):3509-16. doi: 10.1182/blood-2014-10-608596. Epub 2015 Feb 25.

36.

Acquired TTP: ADAMTS13 meets the immune system.

Verbij FC, Fijnheer R, Voorberg J, Sorvillo N.

Blood Rev. 2014 Nov;28(6):227-34. doi: 10.1016/j.blre.2014.07.004. Epub 2014 Aug 15. Review.

PMID:
25213289
37.

Storage and secretion of naturally occurring von Willebrand factor A domain variants.

Groeneveld DJ, Wang JW, Mourik MJ, Dirven RJ, Valentijn KM, Voorberg J, Reitsma PH, Eikenboom J.

Br J Haematol. 2014 Nov;167(4):529-40. doi: 10.1111/bjh.13074. Epub 2014 Aug 8.

PMID:
25103891
38.

Identification of N-linked glycosylation and putative O-fucosylation, C-mannosylation sites in plasma derived ADAMTS13.

Sorvillo N, Kaijen PH, Matsumoto M, Fujimura Y, van der Zwaan C, Verbij FC, Pos W, Fijnheer R, Voorberg J, Meijer AB.

J Thromb Haemost. 2014 May;12(5):670-9.

PMID:
24977290
39.

Individual with subclinical atherosclerosis have impaired proliferation of blood outgrowth endothelial cells, which can be restored by statin therapy.

Martin-Ramirez J, Kok MG, Hofman M, Bierings R, Creemers EE, Meijers JC, Voorberg J, Pinto-Sietsma SJ.

PLoS One. 2014 Jun 23;9(6):e99890. doi: 10.1371/journal.pone.0099890. eCollection 2014.

40.

Decrypting C2 inhibitors.

Voorberg J, Meems H.

Blood. 2014 Apr 24;123(17):2601-2. doi: 10.1182/blood-2014-03-562165. No abstract available.

41.

STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a.

van Breevoort D, Snijders AP, Hellen N, Weckhuysen S, van Hooren KW, Eikenboom J, Valentijn K, Fernandez-Borja M, Ceulemans B, De Jonghe P, Voorberg J, Hannah M, Carter T, Bierings R.

Blood. 2014 May 15;123(20):3185-94. doi: 10.1182/blood-2013-10-535831. Epub 2014 Apr 3.

42.

Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells.

van Hooren KW, Spijkers LJ, van Breevoort D, Fernandez-Borja M, Bierings R, van Buul JD, Alewijnse AE, Peters SL, Voorberg J.

PLoS One. 2014 Mar 14;9(3):e91346. doi: 10.1371/journal.pone.0091346. eCollection 2014.

43.

Phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 regulates epinephrine-induced exocytosis of Weibel-Palade bodies.

van Hooren KW, van Breevoort D, Fernandez-Borja M, Meijer AB, Eikenboom J, Bierings R, Voorberg J.

J Thromb Haemost. 2014 Feb;12(2):273-81. doi: 10.1111/jth.12460.

44.

Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII.

van Haren SD, Wroblewska A, Herczenik E, Kaijen PH, Ruminska A, ten Brinke A, Meijer AB, Voorberg J.

PLoS One. 2013 Nov 14;8(11):e80239. doi: 10.1371/journal.pone.0080239. eCollection 2013.

45.

Rational design of small molecules targeting the C2 domain of coagulation factor VIII.

Nicolaes GA, Kulharia M, Voorberg J, Kaijen PH, Wroblewska A, Wielders S, Schrijver R, Sperandio O, Villoutreix BO.

Blood. 2014 Jan 2;123(1):113-20. doi: 10.1182/blood-2013-05-503227. Epub 2013 Nov 13.

46.

Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis.

McGrath RT, van den Biggelaar M, Byrne B, O'Sullivan JM, Rawley O, O'Kennedy R, Voorberg J, Preston RJ, O'Donnell JS.

Blood. 2013 Dec 12;122(25):4107-10. doi: 10.1182/blood-2013-04-496851. Epub 2013 Oct 8.

47.

von Willebrand factor remodeling during exocytosis from vascular endothelial cells.

Mourik MJ, Valentijn JA, Voorberg J, Koster AJ, Valentijn KM, Eikenboom J.

J Thromb Haemost. 2013 Nov;11(11):2009-19. doi: 10.1111/jth.12401.

48.

Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake.

Bloem E, van den Biggelaar M, Wroblewska A, Voorberg J, Faber JH, Kjalke M, Stennicke HR, Mertens K, Meijer AB.

J Biol Chem. 2013 Oct 11;288(41):29670-9. doi: 10.1074/jbc.M113.473116. Epub 2013 Sep 5.

49.

Acquired thrombotic thrombocytopenic purpura. Development of an autoimmune response.

Schaller M, Studt JD, Voorberg J, Kremer Hovinga JA.

Hamostaseologie. 2013 May 29;33(2):121-30. doi: 10.5482/HAMO-12-12-0023. Epub 2013 Feb 27. Review.

PMID:
23443151
50.

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.

Wang JW, Bouwens EA, Pintao MC, Voorberg J, Safdar H, Valentijn KM, de Boer HC, Mertens K, Reitsma PH, Eikenboom J.

Blood. 2013 Apr 4;121(14):2762-72. doi: 10.1182/blood-2012-06-434373. Epub 2013 Feb 20.

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