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Items: 1 to 50 of 139

1.

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis.

Berkers G, van Mourik P, Vonk AM, Kruisselbrink E, Dekkers JF, de Winter-de Groot KM, Arets HGM, Marck-van der Wilt REP, Dijkema JS, Vanderschuren MM, Houwen RHJ, Heijerman HGM, van de Graaf EA, Elias SG, Majoor CJ, Koppelman GH, Roukema J, Bakker M, Janssens HM, van der Meer R, Vries RGJ, Clevers HC, de Jonge HR, Beekman JM, van der Ent CK.

Cell Rep. 2019 Feb 12;26(7):1701-1708.e3. doi: 10.1016/j.celrep.2019.01.068.

PMID:
30759382
2.

Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass.

Dekker NAM, Veerhoek D, Koning NJ, van Leeuwen ALI, Elbers PWG, van den Brom CE, Vonk ABA, Boer C.

Anaesthesia. 2019 Jan 27. doi: 10.1111/anae.14577. [Epub ahead of print]

PMID:
30687934
3.

Folding-function relationship of the most common cystic fibrosis-causing CFTR conductance mutants.

van Willigen M, Vonk AM, Yeoh HY, Kruisselbrink E, Kleizen B, van der Ent CK, Egmond MR, de Jonge HR, Braakman I, Beekman JM, van der Sluijs P.

Life Sci Alliance. 2019 Jan 18;2(1). pii: e201800172. doi: 10.26508/lsa.201800172. Print 2019 Feb.

4.

Vasculotide, an angiopoietin-1 mimetic, reduces pulmonary vascular leakage and preserves microcirculatory perfusion during cardiopulmonary bypass in rats.

Dekker NAM, van Meurs M, van Leeuwen ALI, Hofland HM, van Slyke P, Vonk ABA, Boer C, van den Brom CE.

Br J Anaesth. 2018 Nov;121(5):1041-1051. doi: 10.1016/j.bja.2018.05.049. Epub 2018 Jun 19.

PMID:
30336848
5.

Male-female differences in aortic valve and combined aortic valve/coronary surgery: a national cohort study in the Netherlands.

Mokhles MM, Soloukey Tbalvandany S, Siregar S, Versteegh MIM, Noyez L, van Putte B, Vonk ABA, Roos-Hesselink JW, Bogers AJJC, Takkenberg JJM.

Open Heart. 2018 Sep 10;5(2):e000868. doi: 10.1136/openhrt-2018-000868. eCollection 2018.

6.

Correction to: Antithrombotic therapy after mitral valve repair: VKA or aspirin?

van der Wall SJ, Olsthoorn JR, Heuts S, Klautz RJM, Tomsic A, Jansen EK, Vonk ABA, Sardari Nia P, Klok FA, Huisman MV.

J Thromb Thrombolysis. 2018 Nov;46(4):482. doi: 10.1007/s11239-018-1735-x.

PMID:
30203248
7.

Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function.

de Winter-de Groot KM, Janssens HM, van Uum RT, Dekkers JF, Berkers G, Vonk A, Kruisselbrink E, Oppelaar H, Vries R, Clevers H, Houwen RHJ, Escher JC, Elias SG, de Jonge HR, de Rijke YB, Tiddens HAWM, van der Ent CK, Beekman JM.

Eur Respir J. 2018 Sep 17;52(3). pii: 1702529. doi: 10.1183/13993003.02529-2017. Print 2018 Sep.

PMID:
30166324
8.

Antithrombotic therapy after mitral valve repair: VKA or aspirin?

van der Wall SJ, Olsthoorn JR, Heuts S, Klautz RJM, Tomsic A, Jansen EK, Vonk ABA, Sardari Nia P, Klok FA, Huisman MV.

J Thromb Thrombolysis. 2018 Nov;46(4):473-481. doi: 10.1007/s11239-018-1724-0. Erratum in: J Thromb Thrombolysis. 2018 Sep 10;:.

9.

Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study.

Schauwvlieghe AFAD, Rijnders BJA, Philips N, Verwijs R, Vanderbeke L, Van Tienen C, Lagrou K, Verweij PE, Van de Veerdonk FL, Gommers D, Spronk P, Bergmans DCJJ, Hoedemaekers A, Andrinopoulou ER, van den Berg CHSB, Juffermans NP, Hodiamont CJ, Vonk AG, Depuydt P, Boelens J, Wauters J; Dutch-Belgian Mycosis study group.

Lancet Respir Med. 2018 Oct;6(10):782-792. doi: 10.1016/S2213-2600(18)30274-1. Epub 2018 Jul 31.

PMID:
30076119
10.

R560S: A class II CFTR mutation that is not rescued by current modulators.

Awatade NT, Ramalho S, Silva IAL, Felício V, Botelho HM, de Poel E, Vonk A, Beekman JM, Farinha CM, Amaral MD.

J Cyst Fibros. 2018 Jul 18. pii: S1569-1993(18)30643-X. doi: 10.1016/j.jcf.2018.07.001. [Epub ahead of print]

PMID:
30030066
11.

Reduction of vascular leakage by imatinib is associated with preserved microcirculatory perfusion and reduced renal injury markers in a rat model of cardiopulmonary bypass.

Koning NJ, de Lange F, van Meurs M, Jongman RM, Ahmed Y, Schwarte LA, van Nieuw Amerongen GP, Vonk ABA, Niessen HW, Baufreton C, Boer C.

Br J Anaesth. 2018 Jun;120(6):1165-1175. doi: 10.1016/j.bja.2017.11.095. Epub 2018 Jan 17.

PMID:
29793583
12.

The diagnosis and treatment of invasive aspergillosis in Dutch haematology units facing a rapidly increasing prevalence of azole-resistance. A nationwide survey and rationale for the DB-MSG 002 study protocol.

Schauwvlieghe AFAD, de Jonge N, van Dijk K, Verweij PE, Brüggemann RJ, Biemond BJ, Bart A, von dem Borne PA, Verbon A, van der Beek MT, Demandt AMP, Oudhuis GJ, Cornelissen JJ, van der Velden WJFM, Span LFR, Kampinga GA, Bruns AH, Vonk AG, Haas PA, Doorduijn JK, Rijnders BJA.

Mycoses. 2018 Apr 23. doi: 10.1111/myc.12788. [Epub ahead of print]

PMID:
29687483
13.

Anticoagulant and side-effects of protamine in cardiac surgery: a narrative review.

Boer C, Meesters MI, Veerhoek D, Vonk ABA.

Br J Anaesth. 2018 May;120(5):914-927. doi: 10.1016/j.bja.2018.01.023. Epub 2018 Feb 26. Review.

PMID:
29661409
14.

Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity.

Zomer-van Ommen DD, de Poel E, Kruisselbrink E, Oppelaar H, Vonk AM, Janssens HM, van der Ent CK, Hagemeijer MC, Beekman JM.

J Cyst Fibros. 2018 May;17(3):316-324. doi: 10.1016/j.jcf.2018.02.007. Epub 2018 Mar 13.

PMID:
29544685
15.

Lung ultrasound compared with chest X-ray in diagnosing postoperative pulmonary complications following cardiothoracic surgery: a prospective observational study.

Touw HR, Parlevliet KL, Beerepoot M, Schober P, Vonk A, Twisk JW, Elbers PW, Boer C, Tuinman PR.

Anaesthesia. 2018 Aug;73(8):946-954. doi: 10.1111/anae.14243. Epub 2018 Mar 12.

16.

Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells.

Schiering C, Vonk A, Das S, Stockinger B, Wincent E.

Biochem Pharmacol. 2018 May;151:47-58. doi: 10.1016/j.bcp.2018.02.031. Epub 2018 Mar 1.

17.

Minimally Invasive Determinations of Oxygen Delivery and Consumption in Cardiac Surgery: An Observational Study.

Burtman DTM, Stolze A, Genaamd Dengler SEK, Vonk ABA, Boer C.

J Cardiothorac Vasc Anesth. 2018 Jun;32(3):1266-1272. doi: 10.1053/j.jvca.2017.06.042. Epub 2017 Jun 27.

18.

Chitinase Induction Prior to Caspofungin Treatment of Experimental Invasive Aspergillosis in Neutropenic Rats Does Not Enhance Survival.

Refos JM, Vonk AG, Ten Kate MT, Verbrugh HA, Bakker-Woudenberg IAJM, van de Sande WWJ.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e00960-17. doi: 10.1128/AAC.00960-17. Print 2018 Jan.

19.

2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.

Task Force on Patient Blood Management for Adult Cardiac Surgery of the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Cardiothoracic Anaesthesiology (EACTA), Boer C, Meesters MI, Milojevic M, Benedetto U, Bolliger D, von Heymann C, Jeppsson A, Koster A, Osnabrugge RL, Ranucci M, Ravn HB, Vonk ABA, Wahba A, Pagano D.

J Cardiothorac Vasc Anesth. 2018 Feb;32(1):88-120. doi: 10.1053/j.jvca.2017.06.026. Epub 2017 Sep 30. Review. No abstract available.

20.

2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.

Pagano D, Milojevic M, Meesters MI, Benedetto U, Bolliger D, von Heymann C, Jeppsson A, Koster A, Osnabrugge RL, Ranucci M, Ravn HB, Vonk ABA, Wahba A, Boer C.

Eur J Cardiothorac Surg. 2018 Jan 1;53(1):79-111. doi: 10.1093/ejcts/ezx325. No abstract available.

PMID:
29029100
21.

Detection of azole-susceptible and azole-resistant Aspergillus coinfection by cyp51A PCR amplicon melting curve analysis.

Schauwvlieghe AFAD, Vonk AG, Buddingh EP, Hoek RAS, Dalm VA, Klaassen CHW, Rijnders BJA.

J Antimicrob Chemother. 2017 Nov 1;72(11):3047-3050. doi: 10.1093/jac/dkx262.

PMID:
28961889
22.

Individual Differences in Heparin Sensitivity and Their Effect on Heparin Anticoagulation During Arterial Vascular Surgery.

Veerhoek D, Groepenhoff F, van der Sluijs MGJM, de Wever JWB, Blankensteijn JD, Vonk ABA, Boer C, Vermeulen CFW.

Eur J Vasc Endovasc Surg. 2017 Oct;54(4):534-541. doi: 10.1016/j.ejvs.2017.07.006. Epub 2017 Aug 9.

23.

Addition of 17-(allylamino)-17-demethoxygeldanamycin to a suboptimal caspofungin treatment regimen in neutropenic rats with invasive pulmonary aspergillosis delays the time to death but does not enhance the overall therapeutic efficacy.

Refos JM, Vonk AG, Ten Kate MT, Eadie K, Verbrugh HA, Bakker-Woudenberg IAJM, van de Sande WWJ.

PLoS One. 2017 Jul 24;12(7):e0180961. doi: 10.1371/journal.pone.0180961. eCollection 2017.

24.

Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study.

van Ingen J, Kohl TA, Kranzer K, Hasse B, Keller PM, Katarzyna Szafrańska A, Hillemann D, Chand M, Schreiber PW, Sommerstein R, Berger C, Genoni M, Rüegg C, Troillet N, Widmer AF, Becker SL, Herrmann M, Eckmanns T, Haller S, Höller C, Debast SB, Wolfhagen MJ, Hopman J, Kluytmans J, Langelaar M, Notermans DW, Ten Oever J, van den Barselaar P, Vonk ABA, Vos MC, Ahmed N, Brown T, Crook D, Lamagni T, Phin N, Smith EG, Zambon M, Serr A, Götting T, Ebner W, Thürmer A, Utpatel C, Spröer C, Bunk B, Nübel U, Bloemberg GV, Böttger EC, Niemann S, Wagner D, Sax H.

Lancet Infect Dis. 2017 Oct;17(10):1033-1041. doi: 10.1016/S1473-3099(17)30324-9. Epub 2017 Jul 12.

PMID:
28711585
25.

PX-18 Protects Human Saphenous Vein Endothelial Cells under Arterial Blood Pressure.

Kupreishvili K, Stooker W, Emmens RW, Vonk ABA, Sipkens JA, van Dijk A, Eijsman L, Quax PH, van Hinsbergh VWM, Krijnen PAJ, Niessen HWM.

Ann Vasc Surg. 2017 Jul;42:293-298. doi: 10.1016/j.avsg.2016.10.063. Epub 2017 Mar 11.

PMID:
28300679
26.

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients.

Boj SF, Vonk AM, Statia M, Su J, Vries RR, Beekman JM, Clevers H.

J Vis Exp. 2017 Feb 11;(120). doi: 10.3791/55159.

27.

Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts.

Kupreishvili K, Meischl C, Vonk ABA, Stooker W, Eijsman L, Blom AM, Quax PHA, van Hinsbergh VWM, Niessen HWM, Krijnen PAJ.

Ann Vasc Surg. 2017 May;41:259-264. doi: 10.1016/j.avsg.2016.10.033. Epub 2017 Feb 3.

PMID:
28163174
28.

Interspecies discrimination of A. fumigatus and siblings A. lentulus and A. felis of the Aspergillus section Fumigati using the AsperGenius® assay.

Chong GM, Vonk AG, Meis JF, Dingemans GJ, Houbraken J, Hagen F, Gaajetaan GR, van Tegelen DW, Simons GF, Rijnders BJ.

Diagn Microbiol Infect Dis. 2017 Mar;87(3):247-252. doi: 10.1016/j.diagmicrobio.2016.11.020. Epub 2016 Dec 5.

29.

Benchmarking the use of blood products in cardiac surgery to stimulate awareness of transfusion behaviour : Results from a four-year longitudinal study.

Brouwers C, Hooftman B, Vonk S, Vonk A, Stooker W, Te Gussinklo WH, Wesselink RM, Wagner C, de Bruijne MC.

Neth Heart J. 2017 Mar;25(3):207-214. doi: 10.1007/s12471-016-0936-1.

30.

Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase.

Hunter SR, Vonk A, Mullen Grey AK, Riddick DS.

Drug Metab Dispos. 2017 Feb;45(2):118-129. doi: 10.1124/dmd.116.073833. Epub 2016 Nov 16.

PMID:
27856527
31.

PCR-based detection of Aspergillus fumigatus Cyp51A mutations on bronchoalveolar lavage: a multicentre validation of the AsperGenius assay® in 201 patients with haematological disease suspected for invasive aspergillosis.

Chong GM, van der Beek MT, von dem Borne PA, Boelens J, Steel E, Kampinga GA, Span LF, Lagrou K, Maertens JA, Dingemans GJ, Gaajetaan GR, van Tegelen DW, Cornelissen JJ, Vonk AG, Rijnders BJ.

J Antimicrob Chemother. 2016 Dec;71(12):3528-3535. Epub 2016 Aug 15.

PMID:
27530755
32.

Validation of a point-of-care prothrombin time test after cardiopulmonary bypass in cardiac surgery.

Meesters MI, Kuiper G, Vonk AB, Loer SA, Boer C.

Anaesthesia. 2016 Oct;71(10):1163-8. doi: 10.1111/anae.13591. Epub 2016 Aug 8.

33.

β2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis.

Vijftigschild LA, Berkers G, Dekkers JF, Zomer-van Ommen DD, Matthes E, Kruisselbrink E, Vonk A, Hensen CE, Heida-Michel S, Geerdink M, Janssens HM, van de Graaf EA, Bronsveld I, de Winter-de Groot KM, Majoor CJ, Heijerman HG, de Jonge HR, Hanrahan JW, van der Ent CK, Beekman JM.

Eur Respir J. 2016 Sep;48(3):768-79. doi: 10.1183/13993003.01661-2015. Epub 2016 Jul 28.

34.

Distribution and dynamics of quinones in the lipid bilayer mimicking the inner membrane of mitochondria.

Kaurola P, Sharma V, Vonk A, Vattulainen I, Róg T.

Biochim Biophys Acta. 2016 Sep;1858(9):2116-2122. doi: 10.1016/j.bbamem.2016.06.016. Epub 2016 Jun 21.

35.

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.

Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM.

Sci Transl Med. 2016 Jun 22;8(344):344ra84. doi: 10.1126/scitranslmed.aad8278.

PMID:
27334259
36.

Mast cells are increased in the media of coronary lesions in patients with myocardial infarction and may favor atherosclerotic plaque instability.

Kupreishvili K, Fuijkschot WW, Vonk AB, Smulders YM, Stooker W, Van Hinsbergh VW, Niessen HW, Krijnen PA.

J Cardiol. 2017 Mar;69(3):548-554. doi: 10.1016/j.jjcc.2016.04.018. Epub 2016 Jun 7.

37.

Effect of high or low protamine dosing on postoperative bleeding following heparin anticoagulation in cardiac surgery. A randomised clinical trial.

Meesters MI, Veerhoek D, de Lange F, de Vries JW, de Jong JR, Romijn JW, Kelchtermans H, Huskens D, van der Steeg R, Thomas PW, Burtman DT, van Barneveld LJ, Vonk AB, Boer C.

Thromb Haemost. 2016 Aug 1;116(2):251-61. doi: 10.1160/TH16-02-0117. Epub 2016 Jun 9.

PMID:
27277211
38.

Male-female differences and survival in patients undergoing isolated mitral valve surgery: a nationwide cohort study in the Netherlands.

Mokhles MM, Siregar S, Versteegh MI, Noyez L, van Putte B, Vonk AB, Roos-Hesselink JW, Bogers AJ, Takkenberg JJ; data registry committee of the Netherlands Association for Cardio-Thoracic Surgery.

Eur J Cardiothorac Surg. 2016 Sep;50(3):482-7. doi: 10.1093/ejcts/ezw151. Epub 2016 May 12.

PMID:
27174553
39.

Potentiator synergy in rectal organoids carrying S1251N, G551D, or F508del CFTR mutations.

Dekkers JF, Van Mourik P, Vonk AM, Kruisselbrink E, Berkers G, de Winter-de Groot KM, Janssens HM, Bronsveld I, van der Ent CK, de Jonge HR, Beekman JM.

J Cyst Fibros. 2016 Sep;15(5):568-78. doi: 10.1016/j.jcf.2016.04.007. Epub 2016 May 5.

40.

Myocardial infarction induces atrial inflammation that can be prevented by C1-esterase inhibitor.

Begieneman MP, Emmens RW, Rijvers L, Woudstra L, Paulus WJ, Kubat B, Vonk AB, van Rossum AC, Wouters D, Zeerleder S, van Ham M, Schalkwijk CG, Niessen HW, Krijnen PA.

J Clin Pathol. 2016 Dec;69(12):1093-1099. doi: 10.1136/jclinpath-2016-203639. Epub 2016 May 6.

PMID:
27153875
41.

Optimal correction of distinct CFTR folding mutants in rectal cystic fibrosis organoids.

Dekkers JF, Gogorza Gondra RA, Kruisselbrink E, Vonk AM, Janssens HM, de Winter-de Groot KM, van der Ent CK, Beekman JM.

Eur Respir J. 2016 Aug;48(2):451-8. doi: 10.1183/13993003.01192-2015. Epub 2016 Apr 21.

42.

Moderate hyperoxic versus near-physiological oxygen targets during and after coronary artery bypass surgery: a randomised controlled trial.

Smit B, Smulders YM, de Waard MC, Boer C, Vonk AB, Veerhoek D, Kamminga S, de Grooth HJ, García-Vallejo JJ, Musters RJ, Girbes AR, Oudemans-van Straaten HM, Spoelstra-de Man AM.

Crit Care. 2016 Mar 10;20:55. doi: 10.1186/s13054-016-1240-6.

43.

Improved Prediction by Dynamic Modeling: An Exploratory Study in the Adult Cardiac Surgery Database of the Netherlands Association for Cardio-Thoracic Surgery.

Siregar S, Nieboer D, Vergouwe Y, Versteegh MI, Noyez L, Vonk AB, Steyerberg EW, Takkenberg JJ.

Circ Cardiovasc Qual Outcomes. 2016 Mar;9(2):171-81. doi: 10.1161/CIRCOUTCOMES.114.001645. Epub 2016 Mar 1.

PMID:
26933048
44.

C4b-Binding Protein Deposition is Induced in Diseased Aortic Heart Valves, Coinciding with C3d.

Dikhoff MJ, ter Weeme M, Vonk AB, Kupreishvili K, Blom AM, Krijnen PA, Stooker W, Niessen HW.

J Heart Valve Dis. 2015 Jul;24(4):451-6.

PMID:
26897815
45.

Prevention of age-induced N(ε)-(carboxymethyl)lysine accumulation in the microvasculature.

Fuijkschot WW, de Graaff HJ, Berishvili E, Kakabadze Z, Kupreishvili K, Meinster E, Houtman M, van Broekhoven A, Schalkwijk CG, Vonk AB, Krijnen PA, Smulders YM, Niessen HW.

Eur J Clin Invest. 2016 Apr;46(4):334-41. doi: 10.1111/eci.12599. Epub 2016 Mar 3.

PMID:
26842530
46.

Endothelial hyperpermeability after cardiac surgery with cardiopulmonary bypass as assessed using an in vitro bioassay for endothelial barrier function.

Koning NJ, Overmars MA, van den Brom CE, van Bezu J, Simon LE, Vonk AB, Girbes AR, van Nieuw Amerongen GP, Boer C.

Br J Anaesth. 2016 Feb;116(2):223-32. doi: 10.1093/bja/aev411.

47.

Ventricular myocarditis coincides with atrial myocarditis in patients.

Begieneman MP, Emmens RW, Rijvers L, Kubat B, Paulus WJ, Vonk AB, Rozendaal L, Biesbroek PS, Wouters D, Zeerleder S, van Ham M, Heymans S, van Rossum AC, Niessen HW, Krijnen PA.

Cardiovasc Pathol. 2016 Mar-Apr;25(2):141-8. doi: 10.1016/j.carpath.2015.12.001. Epub 2015 Dec 4.

PMID:
26764148
48.

Impaired microcirculatory perfusion in a rat model of cardiopulmonary bypass: the role of hemodilution.

Koning NJ, de Lange F, Vonk AB, Ahmed Y, van den Brom CE, Bogaards S, van Meurs M, Jongman RM, Schalkwijk CG, Begieneman MP, Niessen HW, Baufreton C, Boer C.

Am J Physiol Heart Circ Physiol. 2016 Mar 1;310(5):H550-8. doi: 10.1152/ajpheart.00913.2015. Epub 2016 Jan 8.

49.

Echinocandin to fluconazole step-down therapy in critically ill patients with invasive, susceptible Candida albicans infections.

van der Geest PJ, Rijnders BJ, Vonk AG, Groeneveld AB.

Mycoses. 2016 Mar;59(3):179-85. doi: 10.1111/myc.12450. Epub 2015 Dec 28.

PMID:
26707572
50.

Side-by-Side Alterations in Glycocalyx Thickness and Perfused Microvascular Density During Acute Microcirculatory Alterations in Cardiac Surgery.

Koning NJ, Vonk AB, Vink H, Boer C.

Microcirculation. 2016 Jan;23(1):69-74. doi: 10.1111/micc.12260.

PMID:
26638697

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