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Items: 1 to 50 of 84

1.

Extended hepatic metastasectomy for renal cell carcinoma-new aspects in times of targeted therapy: a single-center experience over three decades.

Beetz O, Söffker R, Cammann S, Oldhafer F, Vondran FWR, Imkamp F, Klempnauer J, Kleine M.

Langenbecks Arch Surg. 2020 Jan 14. doi: 10.1007/s00423-019-01852-4. [Epub ahead of print]

PMID:
31938833
2.

Robust hepatitis E virus infection and transcriptional response in human hepatocytes.

Todt D, Friesland M, Moeller N, Praditya D, Kinast V, Brüggemann Y, Knegendorf L, Burkard T, Steinmann J, Burm R, Verhoye L, Wahid A, Meister TL, Engelmann M, Pfankuche VM, Puff C, Vondran FWR, Baumgärtner W, Meuleman P, Behrendt P, Steinmann E.

Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1731-1741. doi: 10.1073/pnas.1912307117. Epub 2020 Jan 2.

3.

A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection.

Ko C, Bester R, Zhou X, Xu Z, Blossey C, Sacherl J, Vondran FWR, Gao L, Protzer U.

Antimicrob Agents Chemother. 2019 Dec 20;64(1). pii: e01440-19. doi: 10.1128/AAC.01440-19. Print 2019 Dec 20.

PMID:
31658963
4.

Abdominal Surgery in Patients with Ventricular Assist Devices: a Single-Center Report.

Beetz O, Bajunaid A, Meißler L, Vondran FWR, Kleine M, Cammann S, Hanke JS, Schmitto JD, Haverich A, Klempnauer J, Ringe KI, Oldhafer F, Timrott K.

ASAIO J. 2019 Oct 23. doi: 10.1097/MAT.0000000000001085. [Epub ahead of print]

PMID:
31651459
5.

Recipient natural killer cells alter the course of rejection of allogeneic heart grafts in rats.

Beetz O, Kolb J, Buck B, Trautewig B, Timrott K, Vondran FWR, Meder I, Löbbert C, Hundrieser J, Klempnauer J, Bektaş H, Lieke T.

PLoS One. 2019 Aug 22;14(8):e0220546. doi: 10.1371/journal.pone.0220546. eCollection 2019.

6.

Alloresponses of Mixed Lymphocyte Hepatocyte Culture to Immunosuppressive Drugs as an In-Vitro Model of Hepatocyte Transplantation.

Oldhafer F, Wittauer EM, Falk CS, DeTemple DE, Beetz O, Timrott K, Kleine M, Vondran FWR.

Ann Transplant. 2019 Aug 13;24:472-480. doi: 10.12659/AOT.915982.

7.

Response to "Critical appraisal of the modified ante situm liver resection-is the original method the better choice?"

Oldhafer F, Ringe KI, Timrott K, Kleine M, Beetz O, Ramackers W, Cammann S, Klempnauer J, Bektas H, Vondran FWR.

Langenbecks Arch Surg. 2019 Aug;404(5):649-651. doi: 10.1007/s00423-019-01795-w. Epub 2019 Jun 29. No abstract available.

PMID:
31256253
8.

Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver.

Kinast V, Leber SL, Brown RJP, Vieyres G, Behrendt P, Eßbach C, Strnad P, Vondran FWR, Cornberg M, Wex C, Pietschmann T, Haybaeck J, Todt D, Steinmann E.

Cells. 2019 Jun 18;8(6). pii: E610. doi: 10.3390/cells8060610.

9.

Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity.

Figueiredo C, Oldhafer F, Wittauer EM, Carvalho-Oliveira M, Akhdar A, Beetz O, Chen-Wacker C, Yuzefovych Y, Falk CS, Blasczyk R, Vondran FWR.

J Cell Mol Med. 2019 Aug;23(8):5705-5714. doi: 10.1111/jcmm.14484. Epub 2019 Jun 10.

10.

Porcine model for the study of liver regeneration enhanced by non-invasive 13C-methacetin breath test (LiMAx test) and permanent portal venous access.

Wittauer EM, Oldhafer F, Augstein E, Beetz O, Kleine M, Schumacher C, Sieg L, Eismann H, Johanning K, Bleich A, Vondran FWR.

PLoS One. 2019 May 31;14(5):e0217488. doi: 10.1371/journal.pone.0217488. eCollection 2019.

11.

Transient increase of activated regulatory T cells early after kidney transplantation.

Mederacke YS, Vondran FW, Kollrich S, Schulde E, Schmitt R, Manns MP, Klempnauer J, Schwinzer R, Noyan F, Jaeckel E.

Sci Rep. 2019 Jan 31;9(1):1021. doi: 10.1038/s41598-018-37218-x.

12.

Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis.

Tsay HC, Yuan Q, Balakrishnan A, Kaiser M, Möbus S, Kozdrowska E, Farid M, Tegtmeyer PK, Borst K, Vondran FWR, Kalinke U, Kispert A, Manns MP, Ott M, Sharma AD.

J Hepatol. 2019 Apr;70(4):722-734. doi: 10.1016/j.jhep.2018.12.016. Epub 2018 Dec 22.

PMID:
30582979
13.

Use of Rotational Thromboelastometry in Liver Transplantation Is Associated With Reduced Transfusion Requirements.

Schumacher C, Eismann H, Sieg L, Friedrich L, Scheinichen D, Vondran FWR, Johanning K.

Exp Clin Transplant. 2019 Apr;17(2):222-230. doi: 10.6002/ect.2017.0236. Epub 2018 Oct 5.

14.

Randomized clinical trial comparing liver resection with and without perioperative assessment of liver function.

Stockmann M, Vondran FWR, Fahrner R, Tautenhahn HM, Mittler J, Bektas H, Malinowski M, Jara M, Klein I, Lock JF; Collaborative Fast‐track Liver Study Group.

BJS Open. 2018 Jun 14;2(5):301-309. doi: 10.1002/bjs5.81. eCollection 2018 Sep.

15.

T5 Exonuclease Hydrolysis of Hepatitis B Virus Replicative Intermediates Allows Reliable Quantification and Fast Drug Efficacy Testing of Covalently Closed Circular DNA by PCR.

Qu B, Ni Y, Lempp FA, Vondran FWR, Urban S.

J Virol. 2018 Nov 12;92(23). pii: e01117-18. doi: 10.1128/JVI.01117-18. Print 2018 Dec 1.

16.

Relevant prognostic factors influencing outcome of patients after surgical resection of distal cholangiocarcinoma.

Beetz O, Klein M, Schrem H, Gwiasda J, Vondran FWR, Oldhafer F, Cammann S, Klempnauer J, Oldhafer KJ, Kleine M.

BMC Surg. 2018 Aug 13;18(1):56. doi: 10.1186/s12893-018-0384-5.

17.

Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice.

Koestner W, Spanier J, Klause T, Tegtmeyer PK, Becker J, Herder V, Borst K, Todt D, Lienenklaus S, Gerhauser I, Detje CN, Geffers R, Langereis MA, Vondran FWR, Yuan Q, van Kuppeveld FJM, Ott M, Staeheli P, Steinmann E, Baumgärtner W, Wacker F, Kalinke U.

PLoS Pathog. 2018 Aug 3;14(8):e1007235. doi: 10.1371/journal.ppat.1007235. eCollection 2018 Aug.

18.

Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.

Bruening J, Lasswitz L, Banse P, Kahl S, Marinach C, Vondran FW, Kaderali L, Silvie O, Pietschmann T, Meissner F, Gerold G.

PLoS Pathog. 2018 Jul 19;14(7):e1007111. doi: 10.1371/journal.ppat.1007111. eCollection 2018 Jul.

19.

Preoperative Recipient Parameters Allow Early Estimation of Postoperative Outcome and Intraoperative Transfusion Requirements in Liver Transplantation.

Schumacher C, Eismann H, Sieg L, Friedrich L, Scheinichen D, Vondran FWR, Johanning K.

Prog Transplant. 2018 Jun;28(2):116-123. doi: 10.1177/1526924818765805. Epub 2018 Mar 20.

PMID:
29558874
20.

Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes.

Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, Schnitzler P, Neumann-Haefelin C, Thimme R, Binder M, Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V.

Gastroenterology. 2018 Jun;154(8):2237-2251.e16. doi: 10.1053/j.gastro.2018.03.020. Epub 2018 Mar 11.

21.

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.

Zhang Z, Filzmayer C, Ni Y, Sültmann H, Mutz P, Hiet MS, Vondran FWR, Bartenschlager R, Urban S.

J Hepatol. 2018 Jul;69(1):25-35. doi: 10.1016/j.jhep.2018.02.021. Epub 2018 Mar 8.

PMID:
29524530
22.

Modified ante situm liver resection without use of cold perfusion nor veno-venous bypass for treatment of hepatic lesions infiltrating the hepatocaval confluence.

Oldhafer F, Ringe KI, Timrott K, Kleine M, Beetz O, Ramackers W, Cammann S, Klempnauer J, Vondran FWR, Bektas H.

Langenbecks Arch Surg. 2018 May;403(3):379-386. doi: 10.1007/s00423-018-1658-1. Epub 2018 Feb 22.

PMID:
29470630
23.

Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles.

Tu T, Budzinska MA, Vondran FWR, Shackel NA, Urban S.

J Virol. 2018 May 14;92(11). pii: e02007-17. doi: 10.1128/JVI.02007-17. Print 2018 Jun 1.

24.

Hepatitis E virus replication and interferon responses in human placental cells.

Knegendorf L, Drave SA, Dao Thi VL, Debing Y, Brown RJP, Vondran FWR, Resner K, Friesland M, Khera T, Engelmann M, Bremer B, Wedemeyer H, Behrendt P, Neyts J, Pietschmann T, Todt D, Steinmann E.

Hepatol Commun. 2018 Jan 8;2(2):173-187. doi: 10.1002/hep4.1138. eCollection 2018 Feb.

25.

Hepatocyte-induced CD4+ T cell alloresponse is associated with major histocompatibility complex class II up-regulation on hepatocytes and suppressible by regulatory T cells.

DeTemple DE, Oldhafer F, Falk CS, Chen-Wacker C, Figueiredo C, Kleine M, Ramackers W, Timrott K, Lehner F, Klempnauer J, Bock M, Vondran FWR.

Liver Transpl. 2018 Mar;24(3):407-419. doi: 10.1002/lt.25019.

26.

Myeloid Dendritic Cells Repress Human Cytomegalovirus Gene Expression and Spread by Releasing Interferon-Unrelated Soluble Antiviral Factors.

Kasmapour B, Kubsch T, Rand U, Eiz-Vesper B, Messerle M, Vondran FWR, Wiegmann B, Haverich A, Cicin-Sain L.

J Virol. 2017 Dec 14;92(1). pii: e01138-17. doi: 10.1128/JVI.01138-17. Print 2018 Jan 1.

27.

Early Tracheostomy Reduces Time of Mechanical Ventilation in Respiratory High-Risk Patients After Liver Transplant.

Cammann S, Timrott K, Vondran FWR, Schrem H, Lehner F, Klempnauer J, Knitsch W, Kleine M.

Exp Clin Transplant. 2018 Oct;16(5):631-634. doi: 10.6002/ect.2017.0113. Epub 2017 Oct 12.

28.

Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry.

Behrendt P, Perin P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meuleman P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, Pietschmann T.

Antiviral Res. 2017 Nov;147:19-28. doi: 10.1016/j.antiviral.2017.09.006. Epub 2017 Sep 18.

PMID:
28923507
29.

Use of the liver maximum function capacity test (LiMAx) for the management of liver resection in cirrhosis - A case of hypopharyngeal cancer liver metastasis.

Cammann S, Oldhafer F, Ringe KI, Ramackers W, Timrott K, Kleine M, Klempnauer J, Lehner F, Bektas H, Vondran FWR.

Int J Surg Case Rep. 2017;39:140-144. doi: 10.1016/j.ijscr.2017.08.003. Epub 2017 Aug 10.

30.

Hepatitis C Virus Strain-Dependent Usage of Apolipoprotein E Modulates Assembly Efficiency and Specific Infectivity of Secreted Virions.

Weller R, Hueging K, Brown RJP, Todt D, Joecks S, Vondran FWR, Pietschmann T.

J Virol. 2017 Aug 24;91(18). pii: e00422-17. doi: 10.1128/JVI.00422-17. Print 2017 Sep 15.

31.

A Case of Recurrent Pneumoperitoneum and Pneumatosis Intestinalis After Bilateral Lung Transplant.

Beetz O, Kleine M, Vondran FWR, Cammann S, Klempnauer J, Kettler B.

Exp Clin Transplant. 2019 Feb;17(1):124-127. doi: 10.6002/ect.2016.0249. Epub 2017 Jun 5.

32.

Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity.

Bankwitz D, Doepke M, Hueging K, Weller R, Bruening J, Behrendt P, Lee JY, Vondran FWR, Manns MP, Bartenschlager R, Pietschmann T.

J Hepatol. 2017 Sep;67(3):480-489. doi: 10.1016/j.jhep.2017.04.010. Epub 2017 Apr 22.

33.

Associating Liver Partition and Portal vein ligation for Staged hepatectomy after pre-operative chemotherapy.

Vondran FWR, Oldhafer F, Ringe KI, Wirth TC, Kleine M, Jäger MD, Klempnauer J, Bektas H.

ANZ J Surg. 2018 Apr;88(4):E324-E328. doi: 10.1111/ans.13944. Epub 2017 Apr 16.

PMID:
28419692
34.

Scavenger receptor class B member 1 (SCARB1) variants modulate hepatitis C virus replication cycle and viral load.

Westhaus S, Deest M, Nguyen ATX, Stanke F, Heckl D, Costa R, Schambach A, Manns MP, Berg T, Vondran FWR, Sarrazin C, Ciesek S, von Hahn T.

J Hepatol. 2017 Aug;67(2):237-245. doi: 10.1016/j.jhep.2017.03.020. Epub 2017 Mar 29.

PMID:
28363797
35.

Sodium taurocholate cotransporting polypeptide is the limiting host factor of hepatitis B virus infection in macaque and pig hepatocytes.

Lempp FA, Wiedtke E, Qu B, Roques P, Chemin I, Vondran FWR, Le Grand R, Grimm D, Urban S.

Hepatology. 2017 Sep;66(3):703-716. doi: 10.1002/hep.29112. Epub 2017 Jul 18.

PMID:
28195359
36.

Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture.

Harak C, Meyrath M, Romero-Brey I, Schenk C, Gondeau C, Schult P, Esser-Nobis K, Saeed M, Neddermann P, Schnitzler P, Gotthardt D, Perez-Del-Pulgar S, Neumann-Haefelin C, Thimme R, Meuleman P, Vondran FW, De Francesco R, Rice CM, Bartenschlager R, Lohmann V.

Nat Microbiol. 2016 Dec 19;2:16247. doi: 10.1038/nmicrobiol.2016.247. Erratum in: Nat Microbiol. 2017 Jan 23;2:17012.

PMID:
27991882
37.

Inactivation of HCV and HIV by microwave: a novel approach for prevention of virus transmission among people who inject drugs.

Siddharta A, Pfaender S, Malassa A, Doerrbecker J, Anggakusuma, Engelmann M, Nugraha B, Steinmann J, Todt D, Vondran FW, Mateu-Gelabert P, Goffinet C, Steinmann E.

Sci Rep. 2016 Nov 18;6:36619. doi: 10.1038/srep36619.

38.

Monitoring of liver function in a 73-year old patient undergoing 'Associating Liver Partition and Portal vein ligation for Staged hepatectomy': case report applying the novel liver maximum function capacity test.

Oldhafer F, Ringe KI, Timrott K, Kleine M, Ramackers W, Cammann S, Jäger MD, Klempnauer J, Bektas H, Vondran FW.

Patient Saf Surg. 2016 Jun 10;10:16. doi: 10.1186/s13037-016-0104-y. eCollection 2016.

39.

Application of the Liver Maximum Function Capacity Test in Acute Liver Failure: A Helpful Tool for Decision-Making in Liver Transplantation?

Vondran FW, Schumacher C, Johanning K, Hartleben B, Knitsch W, Wiesner O, Jaeckel E, Manns MP, Klempnauer J, Bektas H, Lehner F.

Case Rep Transplant. 2016;2016:7074636. doi: 10.1155/2016/7074636. Epub 2016 May 4.

40.

Cholangitis in the postoperative course after biliodigestive anastomosis.

Cammann S, Timrott K, Vonberg RP, Vondran FW, Schrem H, Suerbaum S, Klempnauer J, Bektas H, Kleine M.

Langenbecks Arch Surg. 2016 Aug;401(5):715-24. doi: 10.1007/s00423-016-1450-z. Epub 2016 May 28.

PMID:
27236290
41.

A Depleting Anti-CD45 Monoclonal Antibody as Isolated Conditioning for Bone Marrow Transplantation in the Rat.

Jäger MD, Vondran FW, Ramackers W, Röseler T, Schlitt HJ, Bektas H, Klempnauer J, Timrott K.

PLoS One. 2016 May 3;11(5):e0154682. doi: 10.1371/journal.pone.0154682. eCollection 2016.

42.

ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production.

Vieyres G, Welsch K, Gerold G, Gentzsch J, Kahl S, Vondran FW, Kaderali L, Pietschmann T.

PLoS Pathog. 2016 Apr 28;12(4):e1005568. doi: 10.1371/journal.ppat.1005568. eCollection 2016 Apr.

43.

Immunological aspects of liver cell transplantation.

Oldhafer F, Bock M, Falk CS, Vondran FW.

World J Transplant. 2016 Mar 24;6(1):42-53. doi: 10.5500/wjt.v6.i1.42. Review.

44.

Prediction of survival and tumor recurrence in patients undergoing surgery for pancreatic neuroendocrine neoplasms.

Kaltenborn A, Matzke S, Kleine M, Krech T, Ramackers W, Vondran FW, Klempnauer J, Bektas H, Schrem H.

J Surg Oncol. 2016 Feb;113(2):194-202. doi: 10.1002/jso.24116. Epub 2015 Dec 28.

PMID:
26709239
45.

Intraoperative Conversion to ALPPS in a Case of Intrahepatic Cholangiocarcinoma.

Oldhafer F, Ringe KI, Timrott K, Kleine M, Ramackers W, Cammann S, Jäger MD, Klempnauer J, Bektas H, Vondran FW.

Case Rep Surg. 2015;2015:273641. doi: 10.1155/2015/273641. Epub 2015 Nov 16.

46.

[Transplant Surgeon Meets Nephrologist: Important Nephrological Aspects Before and After Kidney or Liver Transplantation].

Vondran FWR, Wintterle S, Bräsen JH, Haller H, Klempnauer J, Richter N, Lehner F, Schiffer M.

Zentralbl Chir. 2017 Apr;142(2):180-188. doi: 10.1055/s-0035-1557918. Epub 2015 Nov 12. Review. German.

PMID:
26562501
47.

Host cell mTORC1 is required for HCV RNA replication.

Stöhr S, Costa R, Sandmann L, Westhaus S, Pfaender S, Anggakusuma, Dazert E, Meuleman P, Vondran FW, Manns MP, Steinmann E, von Hahn T, Ciesek S.

Gut. 2016 Dec;65(12):2017-2028. doi: 10.1136/gutjnl-2014-308971. Epub 2015 Aug 14.

48.

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

Perin PM, Haid S, Brown RJ, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FW, Speerstra S, Awadh A, Mukhtarov F, Schang LM, Kirschning A, Müller R, Guzman CA, Kaderali L, Randall G, Meuleman P, Ploss A, Pietschmann T.

Hepatology. 2016 Jan;63(1):49-62. doi: 10.1002/hep.28111. Epub 2015 Oct 9.

49.

Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses.

Hueging K, Weller R, Doepke M, Vieyres G, Todt D, Wölk B, Vondran FW, Geffers R, Lauber C, Kaderali L, Penin F, Pietschmann T.

PLoS One. 2015 Jul 30;10(7):e0134529. doi: 10.1371/journal.pone.0134529. eCollection 2015.

50.

Effect of TNF-alpha blockade on coagulopathy and endothelial cell activation in xenoperfused porcine kidneys.

Ramackers W, Klose J, Tiede A, Werwitzke S, Rataj D, Friedrich L, Johanning K, Vondran FW, Bergmann S, Schuettler W, Bockmeyer CL, Becker JU, Klempnauer J, Winkler M.

Xenotransplantation. 2015 Jul-Aug;22(4):284-94. doi: 10.1111/xen.12179. Erratum in: Xenotransplantation. 2015 Nov-Dec;22(6):493.

PMID:
26216261

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