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Items: 1 to 50 of 58

1.

The Anticancer Activity of a First-in-class Small-molecule Targeting PCNA.

Gu L, Lingeman R, Yakushijin F, Sun E, Cui Q, Chao J, Hu W, Li H, Hickey RJ, Stark JM, Yuan YC, Chen Y, Vonderfecht SL, Synold TW, Shi Y, Reckamp KL, Horne D, Malkas LH.

Clin Cancer Res. 2018 Dec 1;24(23):6053-6065. doi: 10.1158/1078-0432.CCR-18-0592. Epub 2018 Jul 2.

PMID:
29967249
2.

miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression.

Magilnick N, Reyes EY, Wang WL, Vonderfecht SL, Gohda J, Inoue JI, Boldin MP.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7140-E7149. doi: 10.1073/pnas.1706833114. Epub 2017 Aug 7.

3.

Analysis of Liver Tumor-Prone Mouse Models of the Hippo Kinase Scaffold Proteins RASSF1A and SAV1.

Zhang X, Guo C, Wu X, Li AX, Liu L, Tsark W, Dammann R, Shen H, Vonderfecht SL, Pfeifer GP.

Cancer Res. 2016 May 1;76(9):2824-35. doi: 10.1158/0008-5472.CAN-15-3010. Epub 2016 Mar 15.

4.

Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model.

Ouyang M, White EE, Ren H, Guo Q, Zhang I, Gao H, Yanyan S, Chen X, Weng Y, Da Fonseca A, Shah S, Manuel ER, Zhang L, Vonderfecht SL, Alizadeh D, Berlin JM, Badie B.

PLoS One. 2016 Feb 1;11(2):e0148139. doi: 10.1371/journal.pone.0148139. eCollection 2016.

5.

Altered lymphopoiesis and immunodeficiency in miR-142 null mice.

Kramer NJ, Wang WL, Reyes EY, Kumar B, Chen CC, Ramakrishna C, Cantin EM, Vonderfecht SL, Taganov KD, Chau N, Boldin MP.

Blood. 2015 Jun 11;125(24):3720-30. doi: 10.1182/blood-2014-10-603951. Epub 2015 Apr 30.

PMID:
25931583
6.

AMG 595, an Anti-EGFRvIII Antibody-Drug Conjugate, Induces Potent Antitumor Activity against EGFRvIII-Expressing Glioblastoma.

Hamblett KJ, Kozlosky CJ, Siu S, Chang WS, Liu H, Foltz IN, Trueblood ES, Meininger D, Arora T, Twomey B, Vonderfecht SL, Chen Q, Hill JS, Fanslow WC.

Mol Cancer Ther. 2015 Jul;14(7):1614-24. doi: 10.1158/1535-7163.MCT-14-1078. Epub 2015 Apr 30.

7.

Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease.

Chen JJ, Liu Q, Yuan C, Gore V, Lopez P, Ma V, Amegadzie A, Qian W, Judd TC, Minatti AE, Brown J, Cheng Y, Xue M, Zhong W, Dineen TA, Epstein O, Human J, Kreiman C, Marx I, Weiss MM, Hitchcock SA, Powers TS, Chen K, Wen PH, Whittington DA, Cheng AC, Bartberger MD, Hickman D, Werner JA, Vargas HM, Everds NE, Vonderfecht SL, Dunn RT 2nd, Wood S, Fremeau RT Jr, White RD, Patel VF.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):767-74. doi: 10.1016/j.bmcl.2014.12.092. Epub 2015 Jan 8.

PMID:
25613679
8.

Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-concept.

Ashton KS, Andrews KL, Bryan MC, Chen J, Chen K, Chen M, Chmait S, Croghan M, Cupples R, Fotsch C, Helmering J, Jordan SR, Kurzeja RJ, Michelsen K, Pennington LD, Poon SF, Sivits G, Van G, Vonderfecht SL, Wahl RC, Zhang J, Lloyd DJ, Hale C, St Jean DJ Jr.

J Med Chem. 2014 Jan 23;57(2):309-24. doi: 10.1021/jm4016735. Epub 2014 Jan 9. Erratum in: J Med Chem. 2014 Mar 27;57(6):2820. Bryan, Marion C [corrected to Bryan, Marian C].

PMID:
24405172
9.

Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.

Lloyd DJ, St Jean DJ Jr, Kurzeja RJ, Wahl RC, Michelsen K, Cupples R, Chen M, Wu J, Sivits G, Helmering J, Komorowski R, Ashton KS, Pennington LD, Fotsch C, Vazir M, Chen K, Chmait S, Zhang J, Liu L, Norman MH, Andrews KL, Bartberger MD, Van G, Galbreath EJ, Vonderfecht SL, Wang M, Jordan SR, Véniant MM, Hale C.

Nature. 2013 Dec 19;504(7480):437-40. doi: 10.1038/nature12724. Epub 2013 Nov 13.

PMID:
24226772
10.

Nonclinical safety evaluation of sunitinib: a potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors.

Patyna S, Arrigoni C, Terron A, Kim TW, Heward JK, Vonderfecht SL, Denlinger R, Turnquist SE, Evering W.

Toxicol Pathol. 2008 Dec;36(7):905-16. doi: 10.1177/0192623308326151. Epub 2008 Nov 3.

PMID:
18981453
11.

Phospholipidosis in nonclinical toxicity studies.

Berridge BR, Chatman LA, Odin M, Schultze AE, Losco PE, Meehan JT, Peters T, Vonderfecht SL; Society of Toxicologic Pathology Scientific and Regulatory Policy Committee Working Group.

Toxicol Pathol. 2007 Feb;35(2):325. No abstract available.

PMID:
17366328
12.

Adoptive transfer of in vitro-stimulated CD4+CD25+ regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis.

Heuer JG, Zhang T, Zhao J, Ding C, Cramer M, Justen KL, Vonderfecht SL, Na S.

J Immunol. 2005 Jun 1;174(11):7141-6.

13.

Epididymal and systemic phospholipidosis in rats and dogs treated with the dopamine D3 selective antagonist PNU-177864.

Rudmann DG, McNerney ME, VanderEide SL, Schemmer JK, Eversole RR, Vonderfecht SL.

Toxicol Pathol. 2004 May-Jun;32(3):326-32.

PMID:
15204974
14.

Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence.

Vonderfecht SL, Stone ML, Eversole RR, Yancey MF, Schuette MR, Duncan BA, Ware JA.

Toxicol Pathol. 2004 May-Jun;32(3):318-25.

PMID:
15204973
15.

Reactive oxygen as modulator of TNF and fas receptor-mediated apoptosis in vivo: studies with glutathione peroxidase-deficient mice.

Bajt ML, Ho YS, Vonderfecht SL, Jaeschke H.

Antioxid Redox Signal. 2002 Oct;4(5):733-40.

PMID:
12470500
16.

Strategic importance of research support through pathology.

Cockerell GL, McKim JM, Vonderfecht SL.

Toxicol Pathol. 2002 Jan-Feb;30(1):4-7. Review.

PMID:
11890474
17.
18.
19.

Involvement of intercellular adhesion molecule-1 in the antigen-induced infiltration of eosinophils and lymphocytes into the airways in a murine model of pulmonary inflammation.

Chin JE, Winterrowd GE, Hatfield CA, Brashler JR, Griffin RL, Vonderfecht SL, Kolbasa KP, Fidler SF, Shull KL, Krzesicki RF, Ready KA, Dunn CJ, Sly LM, Staite ND, Richards IM.

Am J Respir Cell Mol Biol. 1998 Feb;18(2):158-67.

PMID:
9476902
20.
21.

Airway recruitment of leukocytes in mice is dependent on alpha4-integrins and vascular cell adhesion molecule-1.

Chin JE, Hatfield CA, Winterrowd GE, Brashler JR, Vonderfecht SL, Fidler SF, Griffin RL, Kolbasa KP, Krzesicki RF, Sly LM, Staite ND, Richards IM.

Am J Physiol. 1997 Feb;272(2 Pt 1):L219-29.

PMID:
9124372
22.

Role of intercellular adhesion molecule-1 in antigen-induced lung inflammation in brown Norway rats.

Richards IM, Kolbasa KP, Winterrowd GE, Hatfield CA, Vonderfecht SL, Fidler SF, Griffin RL, Brashler JR, Krzesicki RF, Lane CL, Anderson DC, Sly LM, Staite ND, Chin JE.

Am J Physiol. 1996 Aug;271(2 Pt 1):L267-76.

PMID:
8770066
23.

Role of very late activation antigen-4 in the antigen-induced accumulation of eosinophils and lymphocytes in the lungs and airway lumen of sensitized brown Norway rats.

Richards IM, Kolbasa KP, Hatfield CA, Winterrowd GE, Vonderfecht SL, Fidler SF, Griffin RL, Brashler JR, Krzesicki RF, Sly LM, Ready KA, Staite ND, Chin JE.

Am J Respir Cell Mol Biol. 1996 Aug;15(2):172-83.

PMID:
8703473
24.

Phenotypic analysis of airway eosinophils and lymphocytes in a Th-2-driven murine model of pulmonary inflammation.

Watkins AD, Hatfield CA, Fidler SF, Winterrowd GE, Brashler JR, Sun FF, Taylor BM, Vonderfecht SL, Conder GA, Holgate ST, Chin JE, Richards IM.

Am J Respir Cell Mol Biol. 1996 Jul;15(1):20-34.

PMID:
8679219
25.

Release of soluble intercellular adhesion molecule 1 into bile and serum in murine endotoxin shock.

Jaeschke H, Essani NA, Fisher MA, Vonderfecht SL, Farhood A, Smith CW.

Hepatology. 1996 Mar;23(3):530-6.

PMID:
8617433
26.

Borna disease virus p24 and p38/40 synthesized in a baculovirus expression system: virus protein interactions in insect and mammalian cells.

Hsu TA, Carbone KM, Rubin SA, Vonderfecht SL, Eiden JJ.

Virology. 1994 Nov 1;204(2):854-9.

PMID:
7524242
27.

The 21-aminosteroid tirilazad mesylate protects against endotoxin shock and acute liver failure in rats.

Liu P, Vonderfecht SL, McGuire GM, Fisher MA, Farhood A, Jaeschke H.

J Pharmacol Exp Ther. 1994 Oct;271(1):438-45.

PMID:
7965745
28.
29.
30.

Group B rotavirus VP2: sequence analysis, expression, and gene coding assignment.

Lindsay DA, Vonderfecht SL, Eiden JJ.

Virology. 1994 Feb 15;199(1):141-50.

PMID:
8116237
31.
32.

Baculovirus expression of gene 6 of the IDIR strain of group B rotavirus (GBR): coding assignment of the major inner capsid protein.

Lindsay DA, Vonderfecht SL, Betenbaugh MJ, Eiden JJ.

Virology. 1993 Mar;193(1):367-75.

PMID:
8382401
33.

Diarrhea caused by a slow-growing Enterococcus-like agent in neonatal rats.

Etheridge ME, Vonderfecht SL.

Lab Anim Sci. 1992 Dec;42(6):548-50.

PMID:
1479804
34.

Human milk mucin inhibits rotavirus replication and prevents experimental gastroenteritis.

Yolken RH, Peterson JA, Vonderfecht SL, Fouts ET, Midthun K, Newburg DS.

J Clin Invest. 1992 Nov;90(5):1984-91.

35.

Immunocytochemical localization of platelets in baboon hepatic sinusoids using monoclonal mouse anti-human platelet glycoprotein IIIa following induction of thrombocytopenia.

Frank JD, Gould RJ, Schaffer LW, Davidson JT, Gibson RE, Patrick DH, Vonderfecht SL, Cartwright ME.

Histochemistry. 1992 May;97(4):355-60.

PMID:
1618650
36.
37.

Growth of group A rotaviruses in a human liver cell line.

Schwarz KB, Moore TJ, Willoughby RE Jr, Wee SB, Vonderfecht SL, Yolken RH.

Hepatology. 1990 Oct;12(4 Pt 1):638-43.

PMID:
2170264
38.

Pathology of infectious diarrhea of infant rats (IDIR) induced by an antigenically distinct rotavirus.

Huber AC, Yolken RH, Mader LC, Strandberg JD, Vonderfecht SL.

Vet Pathol. 1989 Sep;26(5):376-85.

PMID:
2555957
39.

Detection of group B rotavirus in fecal specimens by dot hybridization with a cloned cDNA probe.

Eiden JJ, Firoozmand F, Sato S, Vonderfecht SL, Yin FZ, Yolken RH.

J Clin Microbiol. 1989 Mar;27(3):422-6.

40.

Monoclonal antibody assay for detection of double-stranded RNA and application for detection of group A and non-group A rotaviruses.

Kinney JS, Viscidi RP, Vonderfecht SL, Eiden JJ, Yolken RH.

J Clin Microbiol. 1989 Jan;27(1):6-12.

41.

Protease inhibitors suppress the in vitro and in vivo replication of rotavirus.

Vonderfecht SL, Miskuff RL, Wee SB, Sato S, Tidwell RR, Geratz JD, Yolken RH.

J Clin Invest. 1988 Dec;82(6):2011-6.

42.

Enterococcus hirae implicated as a cause of diarrhea in suckling rats.

Etheridge ME, Yolken RH, Vonderfecht SL.

J Clin Microbiol. 1988 Sep;26(9):1741-4.

43.

Terminal fingerprint analysis of group B rotaviruses.

Eiden JJ, Yolken RH, Vonderfecht SL, Tao H, McCrae MA.

J Infect Dis. 1988 Sep;158(3):657-8. No abstract available.

PMID:
2842411
44.

Duration and pattern of asymptomatic rotavirus shedding by hospitalized children.

Eiden JJ, Verleur DG, Vonderfecht SL, Yolken RH.

Pediatr Infect Dis J. 1988 Aug;7(8):564-9.

PMID:
2845347
45.

Kinetics of intestinal replication of group B rotavirus and relevance to diagnostic methods.

Vonderfecht SL, Eiden JJ, Miskuff RL, Yolken RH.

J Clin Microbiol. 1988 Feb;26(2):216-21.

46.

Comparison of methods for detection of serum antibody to murine rotavirus.

Ferner WT, Miskuff RL, Yolken RH, Vonderfecht SL.

J Clin Microbiol. 1987 Aug;25(8):1364-9.

47.

Homotypic and heterotypic antibodies for prevention of experimental rotavirus gastroenteritis.

Losonsky GA, Vonderfecht SL, Eiden J, Wee SB, Yolken RH.

J Clin Microbiol. 1986 Dec;24(6):1041-4.

48.

Identification of a bovine enteric syncytial virus as a nongroup A rotavirus.

Vonderfecht SL, Eiden JJ, Torres A, Miskuff RL, Mebus CA, Yolken RH.

Am J Vet Res. 1986 Sep;47(9):1913-8.

PMID:
3021026
50.

Pathology of larval Eustrongylides in the rabbit.

Shirazian D, Schiller EL, Glaser CA, Vonderfecht SL.

J Parasitol. 1984 Oct;70(5):803-6.

PMID:
6512643

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