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Items: 29

1.

Highly specific and selective anti-pS396-tau antibody C10.2 targets seeding-competent tau.

Rosenqvist N, Asuni AA, Andersson CR, Christensen S, Daechsel JA, Egebjerg J, Falsig J, Helboe L, Jul P, Kartberg F, Pedersen LØ, Sigurdsson EM, Sotty F, Skjødt K, Stavenhagen JB, Volbracht C, Pedersen JT.

Alzheimers Dement (N Y). 2018 Oct 14;4:521-534. doi: 10.1016/j.trci.2018.09.005. eCollection 2018.

2.

Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.

Chukwu JE, Pedersen JT, Pedersen LØ, Volbracht C, Sigurdsson EM, Kong XP.

Sci Rep. 2018 Apr 18;8(1):6209. doi: 10.1038/s41598-018-24276-4.

3.

Early depletion of CA1 neurons and late neurodegeneration in a mouse tauopathy model.

Helboe L, Egebjerg J, Barkholt P, Volbracht C.

Brain Res. 2017 Jun 15;1665:22-35. doi: 10.1016/j.brainres.2017.04.002. Epub 2017 Apr 11.

PMID:
28411086
4.

Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model.

Jul P, Volbracht C, de Jong IE, Helboe L, Elvang AB, Pedersen JT.

J Alzheimers Dis. 2016;49(3):783-95. doi: 10.3233/JAD-150292.

PMID:
26519432
5.

Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions.

Filser S, Ovsepian SV, Masana M, Blazquez-Llorca L, Brandt Elvang A, Volbracht C, Müller MB, Jung CK, Herms J.

Biol Psychiatry. 2015 Apr 15;77(8):729-39. doi: 10.1016/j.biopsych.2014.10.013. Epub 2014 Oct 29.

PMID:
25599931
6.

The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function.

Jensen T, Elster L, Nielsen SM, Poda SB, Loechel F, Volbracht C, Klewe IV, David L, Watson SP.

Bioorg Med Chem Lett. 2014 Nov 15;24(22):5195-8. doi: 10.1016/j.bmcl.2014.09.077. Epub 2014 Oct 2.

PMID:
25442311
7.

Altered function of hippocampal CA1 pyramidal neurons in the rTg4510 mouse model of tauopathy.

Dalby NO, Volbracht C, Helboe L, Larsen PH, Jensen HS, Egebjerg J, Elvang AB.

J Alzheimers Dis. 2014;40(2):429-42. doi: 10.3233/JAD-131358.

PMID:
24448785
8.

Characteristics of TBS-extractable hyperphosphorylated tau species: aggregation intermediates in rTg4510 mouse brain.

Sahara N, DeTure M, Ren Y, Ebrahim AS, Kang D, Knight J, Volbracht C, Pedersen JT, Dickson DW, Yen SH, Lewis J.

J Alzheimers Dis. 2013;33(1):249-63. doi: 10.3233/JAD-2012-121093.

9.

Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.

Kuhn PH, Koroniak K, Hogl S, Colombo A, Zeitschel U, Willem M, Volbracht C, Schepers U, Imhof A, Hoffmeister A, Haass C, Roßner S, Bräse S, Lichtenthaler SF.

EMBO J. 2012 Jun 22;31(14):3157-68. doi: 10.1038/emboj.2012.173.

10.

Memantine potentiates hippocampal θ oscillations at a therapeutic dose in anesthetized mice: a mechanistic link to its cognitive-enhancing properties.

Guadagna S, Bundgaard C, Hovelsø N, Volbracht C, Francis PT, Egebjerg J, Sotty F.

Neuropharmacology. 2012 Jun;62(7):2208-18. doi: 10.1016/j.neuropharm.2012.01.014. Epub 2012 Jan 24.

PMID:
22300835
11.

Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.

Bittner T, Fuhrmann M, Burgold S, Jung CK, Volbracht C, Steiner H, Mitteregger G, Kretzschmar HA, Haass C, Herms J.

J Neurosci. 2009 Aug 19;29(33):10405-9. doi: 10.1523/JNEUROSCI.2288-09.2009.

12.

Differential effects of gamma-secretase and BACE1 inhibition on brain Abeta levels in vitro and in vivo.

Elvang AB, Volbracht C, Pedersen LØ, Jensen KG, Karlsson JJ, Larsen SA, Mørk A, Stensbøl TB, Bastlund JF.

J Neurochem. 2009 Sep;110(5):1377-87. doi: 10.1111/j.1471-4159.2009.06215.x. Epub 2009 Jun 10.

13.

Measurement of cellular beta-site of APP cleaving enzyme 1 activity and its modulation in neuronal assay systems.

Volbracht C, Penzkofer S, Mansson D, Christensen KV, Fog K, Schildknecht S, Leist M, Nielsen J.

Anal Biochem. 2009 Apr 15;387(2):208-20. doi: 10.1016/j.ab.2009.01.008. Epub 2009 Jan 15.

PMID:
19454261
14.

Wide spectrum modulation by KP-544 in models relevant for neuronal survival.

Geist MA, Volbracht C, Podhorna J, Falsig J, Leist M.

Neuroreport. 2007 Apr 16;18(6):571-5.

PMID:
17413659
15.

Attenuated amyloid-beta aggregation and neurotoxicity owing to methionine oxidation.

Johansson AS, Bergquist J, Volbracht C, Päiviö A, Leist M, Lannfelt L, Westlind-Danielsson A.

Neuroreport. 2007 Apr 16;18(6):559-63.

PMID:
17413657
16.

Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity.

Volbracht C, van Beek J, Zhu C, Blomgren K, Leist M.

Eur J Neurosci. 2006 May;23(10):2611-22.

PMID:
16817864
17.

The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide.

Volbracht C, Chua BT, Ng CP, Bahr BA, Hong W, Li P.

J Neurochem. 2005 Jun;93(5):1280-92. Erratum in: J Neurochem. 2005 Sep;94(5):1471.

18.

Mitochondrial translocation of cofilin is an early step in apoptosis induction.

Chua BT, Volbracht C, Tan KO, Li R, Yu VC, Li P.

Nat Cell Biol. 2003 Dec;5(12):1083-9. Epub 2003 Nov 23.

PMID:
14634665
19.

Calpain inhibitors prevent nitric oxide-triggered excitotoxic apoptosis.

Volbracht C, Fava E, Leist M, Nicotera P.

Neuroreport. 2001 Dec 4;12(17):3645-8.

PMID:
11726766
20.

Apoptosis in caspase-inhibited neurons.

Volbracht C, Leist M, Kolb SA, Nicotera P.

Mol Med. 2001 Jan;7(1):36-48.

21.

Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis.

Gerhardt E, Kügler S, Leist M, Beier C, Berliocchi L, Volbracht C, Weller M, Bähr M, Nicotera P, Schulz JB.

Mol Cell Neurosci. 2001 Apr;17(4):717-31.

PMID:
11312607
22.

Energy requirement for caspase activation and neuronal cell death.

Nicotera P, Leist M, Fava E, Berliocchi L, Volbracht C.

Brain Pathol. 2000 Apr;10(2):276-82. Review.

PMID:
10764047
23.

Execution of apoptosis: converging or diverging pathways?

Nicotera P, Leist M, Single B, Volbracht C.

Biol Chem. 1999 Sep;380(9):1035-40. Review.

PMID:
10543440
24.
25.

CD95-Mediated murine hepatic apoptosis requires an intact glutathione status.

Hentze H, Künstle G, Volbracht C, Ertel W, Wendel A.

Hepatology. 1999 Jul;30(1):177-85.

PMID:
10385654
26.

The expression of plasma membrane Ca2+ pump isoforms in cerebellar granule neurons is modulated by Ca2+.

Guerini D, García-Martin E, Gerber A, Volbracht C, Leist M, Merino CG, Carafoli E.

J Biol Chem. 1999 Jan 15;274(3):1667-76.

27.

1-Methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation, and neuronal apoptosis.

Leist M, Volbracht C, Fava E, Nicotera P.

Mol Pharmacol. 1998 Nov;54(5):789-801.

PMID:
9804614
28.

Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide.

Leist M, Volbracht C, Kühnle S, Fava E, Ferrando-May E, Nicotera P.

Mol Med. 1997 Nov;3(11):750-64.

29.

Apoptosis in the absence of poly-(ADP-ribose) polymerase.

Leist M, Single B, Künstle G, Volbracht C, Hentze H, Nicotera P.

Biochem Biophys Res Commun. 1997 Apr 17;233(2):518-22.

PMID:
9144569

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