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Items: 1 to 50 of 257

1.

An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin.

Coufalova D, Remnant L, Hernychova L, Muller P, Healy A, Kannan S, Westwood N, Verma CS, Vojtesek B, Hupp TR, Houston DR.

J Proteomics. 2019 Mar 9;199:89-101. doi: 10.1016/j.jprot.2019.02.012. [Epub ahead of print]

PMID:
30862565
2.

The role of miR-409-3p in regulation of HPV16/18-E6 mRNA in human cervical high-grade squamous intraepithelial lesions.

Sommerova L, Anton M, Bouchalova P, Jasickova H, Rak V, Jandakova E, Selingerova I, Bartosik M, Vojtesek B, Hrstka R.

Antiviral Res. 2019 Mar;163:185-192. doi: 10.1016/j.antiviral.2019.01.019. Epub 2019 Jan 31.

PMID:
30711417
3.

Radiation-induced astrocyte senescence is rescued by Δ133p53.

Turnquist C, Beck JA, Horikawa I, Obiorah IE, Von Muhlinen N, Vojtesek B, Lane DP, Grunseich C, Chahine JJ, Ames HM, Smart DD, Harris BT, Harris CC.

Neuro Oncol. 2019 Mar 18;21(4):474-485. doi: 10.1093/neuonc/noz001.

PMID:
30615147
4.

Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding.

Trcka F, Durech M, Vankova P, Chmelik J, Martinkova V, Hausner J, Kadek A, Marcoux J, Klumpler T, Vojtesek B, Muller P, Man P.

Mol Cell Proteomics. 2019 Feb;18(2):320-337. doi: 10.1074/mcp.RA118.001044. Epub 2018 Nov 20.

PMID:
30459217
5.

Genomagnetic LAMP-based electrochemical test for determination of high-risk HPV16 and HPV18 in clinical samples.

Bartosik M, Jirakova L, Anton M, Vojtesek B, Hrstka R.

Anal Chim Acta. 2018 Dec 26;1042:37-43. doi: 10.1016/j.aca.2018.08.020. Epub 2018 Aug 11.

PMID:
30428986
6.

Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition.

Pastorek M, Muller P, Coates PJ, Vojtesek B.

PLoS One. 2018 Aug 23;13(8):e0202758. doi: 10.1371/journal.pone.0202758. eCollection 2018.

7.

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 May 22;9(1):2071. doi: 10.1038/s41467-018-04198-5.

8.

Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses.

Wang ECY, Pjechova M, Nightingale K, Vlahava VM, Patel M, Ruckova E, Forbes SK, Nobre L, Antrobus R, Roberts D, Fielding CA, Seirafian S, Davies J, Murrell I, Lau B, Wilkie GS, Suárez NM, Stanton RJ, Vojtesek B, Davison A, Lehner PJ, Weekes MP, Wilkinson GWG, Tomasec P.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):4998-5003. doi: 10.1073/pnas.1720950115. Epub 2018 Apr 24.

9.

STAT3, stem cells, cancer stem cells and p63.

Galoczova M, Coates P, Vojtesek B.

Cell Mol Biol Lett. 2018 Mar 22;23:12. doi: 10.1186/s11658-018-0078-0. eCollection 2018. Review.

10.

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 Mar 16;9(1):1107. doi: 10.1038/s41467-018-03441-3. Erratum in: Nat Commun. 2018 May 22;9(1):2071.

11.

p63 isoforms in triple-negative breast cancer: ΔNp63 associates with the basal phenotype whereas TAp63 associates with androgen receptor, lack of BRCA mutation, PTEN and improved survival.

Coates PJ, Nenutil R, Holcakova J, Nekulova M, Podhorec J, Svoboda M, Vojtesek B.

Virchows Arch. 2018 Mar;472(3):351-359. doi: 10.1007/s00428-018-2324-2. Epub 2018 Feb 27.

PMID:
29484502
12.

p53 isoforms regulate premature aging in human cells.

von Muhlinen N, Horikawa I, Alam F, Isogaya K, Lissa D, Vojtesek B, Lane DP, Harris CC.

Oncogene. 2018 May;37(18):2379-2393. doi: 10.1038/s41388-017-0101-3. Epub 2018 Feb 12.

13.

Microgradient separation technique for purification and fractionation of permethylated N-glycans before mass spectrometric analyses.

Rehulka P, Zahradnikova M, Rehulkova H, Dvorakova P, Nenutil R, Valik D, Vojtesek B, Hernychova L, Novotny MV.

J Sep Sci. 2018 May;41(9):1973-1982. doi: 10.1002/jssc.201701339. Epub 2018 Mar 6.

PMID:
29392831
14.

The Sequence-specific Peptide-binding Activity of the Protein Sulfide Isomerase AGR2 Directs Its Stable Binding to the Oncogenic Receptor EpCAM.

Mohtar MA, Hernychova L, O'Neill JR, Lawrence ML, Murray E, Vojtesek B, Hupp TR.

Mol Cell Proteomics. 2018 Apr;17(4):737-763. doi: 10.1074/mcp.RA118.000573. Epub 2018 Jan 16.

15.

Evidence for allosteric effects on p53 oligomerization induced by phosphorylation.

Muller P, Chan JM, Simoncik O, Fojta M, Lane DP, Hupp T, Vojtesek B.

Protein Sci. 2018 Feb;27(2):523-530. doi: 10.1002/pro.3344. Epub 2017 Dec 8.

16.

Corrigendum: The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.

Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M.

Genes Dev. 2017 Sep 15;31(18):1926. doi: 10.1101/gad.307207.117. No abstract available.

17.

Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition.

Sommerova L, Ondrouskova E, Vojtesek B, Hrstka R.

BMC Cancer. 2017 Aug 15;17(1):546. doi: 10.1186/s12885-017-3537-5.

18.

[Diagnostic and Therapeutic Potential of Membrane HSP90].

Vacek O, Pastorek M, Durech M, Vojtěšek B, Müller P.

Klin Onkol. 2017 Spring;30(Supplementum1):191-194. Czech.

PMID:
28471204
19.

[Ascites May Provide Useful Information for Diagnosis of Ovarian Cancer].

Stuchlíková E, Zahradníková M, Nenutil R, Valík D, Vojtěšek B, Novotný M, Hernychova L.

Klin Onkol. 2017 Spring;30(Supplementum1):187-190. Czech.

PMID:
28471203
20.

[Application of PLA Method for Detection of p53/p63/p73 Complexes in Situ in Tumour Cells and Tumour Tissue].

Hrabal V, Nekulová M, Nenutil R, Holčaková J, Coates PJ, Vojtěšek B.

Klin Onkol. 2017 Spring;30(Supplementum1):159-162. Czech.

PMID:
28471195
21.

Regulation of AGR2 expression via 3'UTR shortening.

Matoulkova E, Sommerova L, Pastorek M, Vojtesek B, Hrstka R.

Exp Cell Res. 2017 Jul 1;356(1):40-47. doi: 10.1016/j.yexcr.2017.04.011. Epub 2017 Apr 11.

PMID:
28408318
22.

Tamoxifen-Dependent Induction of AGR2 Is Associated with Increased Aggressiveness of Endometrial Cancer Cells.

Hrstka R, Podhorec J, Nenutil R, Sommerova L, Obacz J, Durech M, Faktor J, Bouchal P, Skoupilova H, Vojtesek B.

Cancer Invest. 2017 May 28;35(5):313-324. doi: 10.1080/07357907.2017.1309546. Epub 2017 Apr 12.

PMID:
28402678
23.

Mutations in the TP53 gene affected recruitment of 53BP1 protein to DNA lesions, but level of 53BP1 was stable after γ-irradiation that depleted MDC1 protein in specific TP53 mutants.

Suchánková J, Legartová S, Ručková E, Vojtěšek B, Kozubek S, Bártová E.

Histochem Cell Biol. 2017 Sep;148(3):239-255. doi: 10.1007/s00418-017-1567-3. Epub 2017 Apr 10.

PMID:
28397142
24.

ΔNp63 activates EGFR signaling to induce loss of adhesion in triple-negative basal-like breast cancer cells.

Holcakova J, Nekulova M, Orzol P, Nenutil R, Podhorec J, Svoboda M, Dvorakova P, Pjechova M, Hernychova L, Vojtesek B, Coates PJ.

Breast Cancer Res Treat. 2017 Jun;163(3):475-484. doi: 10.1007/s10549-017-4216-6. Epub 2017 Mar 27.

PMID:
28349272
25.

Quantitative Shotgun Proteomics Unveils Candidate Novel Esophageal Adenocarcinoma (EAC)-specific Proteins.

O'Neill JR, Pak HS, Pairo-Castineira E, Save V, Paterson-Brown S, Nenutil R, Vojtěšek B, Overton I, Scherl A, Hupp TR.

Mol Cell Proteomics. 2017 Jun;16(6):1138-1150. doi: 10.1074/mcp.M116.065078. Epub 2017 Mar 23.

26.

AGR2 associates with HER2 expression predicting poor outcome in subset of estrogen receptor negative breast cancer patients.

Ondrouskova E, Sommerova L, Nenutil R, Coufal O, Bouchal P, Vojtesek B, Hrstka R.

Exp Mol Pathol. 2017 Apr;102(2):280-283. doi: 10.1016/j.yexmp.2017.02.016. Epub 2017 Feb 24.

PMID:
28238761
27.

Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation.

Fielding CA, Weekes MP, Nobre LV, Ruckova E, Wilkie GS, Paulo JA, Chang C, Suárez NM, Davies JA, Antrobus R, Stanton RJ, Aicheler RJ, Nichols H, Vojtesek B, Trowsdale J, Davison AJ, Gygi SP, Tomasec P, Lehner PJ, Wilkinson GW.

Elife. 2017 Feb 10;6. pii: e22206. doi: 10.7554/eLife.22206.

28.

Immunoassays of chemically modified polysaccharides, glycans in glycoproteins and ribose in nucleic acids.

Strmečki S, Trefulka M, Zatloukalová P, Durech M, Vojtesek B, Paleček E.

Anal Chim Acta. 2017 Feb 22;955:108-115. doi: 10.1016/j.aca.2016.12.013. Epub 2016 Dec 26.

PMID:
28088277
29.

Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

Galtsidis S, Logotheti S, Pavlopoulou A, Zampetidis CP, Papachristopoulou G, Scorilas A, Vojtesek B, Gorgoulis V, Zoumpourlis V.

Cancer Lett. 2017 Mar 1;388:96-106. doi: 10.1016/j.canlet.2016.11.036. Epub 2016 Dec 3.

PMID:
27919789
30.

[New Technologies for In Vivo Cancer Diagnostics].

Hernychova L, Coufalová D, Michalova E, Nenutil R, Vojtěšek B.

Klin Onkol. Fall 2016;29 Suppl 4(Suppl 4):88-94. Review. Czech.

PMID:
27846726
31.

[The Role of PD-1/PD-L1 Signaling Pathway in Antitumor Immune Response].

Zatloukalová P, Pjechová M, Babčanová S, Hupp TR, Vojtěšek B.

Klin Onkol. Fall 2016;29 Suppl 4(Suppl 4):72-77. Review. Czech.

PMID:
27846724
32.

[Utilization of Hydrogen/Deuterium Exchange in Biopharmaceutical Industry].

Coufalová D, Vojtěšek B, Hernychova L.

Klin Onkol. Fall 2016;29 Suppl 4(Suppl 4):59-63. Review. Czech.

PMID:
27846722
33.

[Molecular Mechanisms of Carcinogenesis of Epithelial Ovarian Cancers].

Müllerová Z, Müller T, Křivánková K, Vojtěšek B, Müller P.

Klin Onkol. Fall 2016;29 Suppl 4(Suppl 4):46-53. Review. Czech.

PMID:
27846720
34.

[Impact of HSP90 Inhibition on Viability and Cell Cycle in Relation to p53 Status].

Pastorek M, Müller P, Vojtěšek B.

Klin Onkol. Fall 2016;29 Suppl 4(Suppl 4):40-45. Czech.

PMID:
27846719
35.

[Endoplasmic Reticulum Chaperones at the Tumor Cell Surface and in the Extracellular Space].

Brychtová V, Vojtěšek B.

Klin Onkol. Fall 2016;29 Suppl 4(Suppl 4):25-30. Review. Czech.

PMID:
27846717
36.

[Mechanisms of Protein Homeostasis Regulation in Cancer Development].

Trčka F, Müller P, Vojtěšek B.

Klin Onkol. Fall 2016;29 Suppl 4(Suppl 4):18-24. Czech.

PMID:
27846716
37.

ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells.

Nekulova M, Holcakova J, Gu X, Hrabal V, Galtsidis S, Orzol P, Liu Y, Logotheti S, Zoumpourlis V, Nylander K, Coates PJ, Vojtesek B.

BMC Cancer. 2016 Oct 10;16(1):782.

38.

p53 binds the mdmx mRNA and controls its translation.

Tournillon AS, López I, Malbert-Colas L, Findakly S, Naski N, Olivares-Illana V, Karakostis K, Vojtesek B, Nylander K, Fåhraeus R.

Oncogene. 2017 Feb 2;36(5):723-730. doi: 10.1038/onc.2016.236. Epub 2016 Jul 4.

PMID:
27375027
39.

IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation.

Hároníková L, Coufal J, Kejnovská I, Jagelská EB, Fojta M, Dvořáková P, Muller P, Vojtesek B, Brázda V.

PLoS One. 2016 Jun 9;11(6):e0157156. doi: 10.1371/journal.pone.0157156. eCollection 2016.

40.

Rearrangement of mitochondrial pyruvate dehydrogenase subunit dihydrolipoamide dehydrogenase protein-protein interactions by the MDM2 ligand nutlin-3.

Way L, Faktor J, Dvorakova P, Nicholson J, Vojtesek B, Graham D, Ball KL, Hupp T.

Proteomics. 2016 Sep;16(17):2327-44. doi: 10.1002/pmic.201500501.

41.

Electrochemical chip-based genomagnetic assay for detection of high-risk human papillomavirus DNA.

Bartosik M, Durikova H, Vojtesek B, Anton M, Jandakova E, Hrstka R.

Biosens Bioelectron. 2016 Sep 15;83:300-5. doi: 10.1016/j.bios.2016.04.035. Epub 2016 Apr 14.

PMID:
27132004
42.

Erratum to: ΔNp63 regulates cell proliferation, differentiation, adhesion, and migration in the BL2 subtype of basal-like breast cancer.

Orzol P, Nekulova M, Holcakova J, Muller P, Vojtesek B, Coates PJ.

Tumour Biol. 2016 Jun;37(6):8469. No abstract available.

PMID:
27113740
43.

p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration.

Turnquist C, Horikawa I, Foran E, Major EO, Vojtesek B, Lane DP, Lu X, Harris BT, Harris CC.

Cell Death Differ. 2016 Sep 1;23(9):1515-28. doi: 10.1038/cdd.2016.37. Epub 2016 Apr 22.

44.

Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance.

Gibadulinova A, Pastorek M, Filipcik P, Radvak P, Csaderova L, Vojtesek B, Pastorekova S.

Oncotarget. 2016 Apr 19;7(16):22508-22. doi: 10.18632/oncotarget.7999.

45.

Novel Entropically Driven Conformation-specific Interactions with Tomm34 Protein Modulate Hsp70 Protein Folding and ATPase Activities.

Durech M, Trcka F, Man P, Blackburn EA, Hernychova L, Dvorakova P, Coufalova D, Kavan D, Vojtesek B, Muller P.

Mol Cell Proteomics. 2016 May;15(5):1710-27. doi: 10.1074/mcp.M116.058131. Epub 2016 Mar 4.

46.

The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine.

Jain S, Aresu L, Comazzi S, Shi J, Worrall E, Clayton J, Humphries W, Hemmington S, Davis P, Murray E, Limeneh AA, Ball K, Ruckova E, Muller P, Vojtesek B, Fahraeus R, Argyle D, Hupp TR.

PLoS One. 2016 Feb 19;11(2):e0148366. doi: 10.1371/journal.pone.0148366. eCollection 2016.

47.

Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond.

Clarke DJ, Murray E, Faktor J, Mohtar A, Vojtesek B, MacKay CL, Smith PL, Hupp TR.

Biochim Biophys Acta. 2016 May;1864(5):551-61. doi: 10.1016/j.bbapap.2016.02.011. Epub 2016 Feb 10.

PMID:
26876500
48.

p53 mRNA and p53 Protein Structures Have Evolved Independently to Interact with MDM2.

Karakostis K, Ponnuswamy A, Fusée LT, Bailly X, Laguerre L, Worall E, Vojtesek B, Nylander K, Fåhraeus R.

Mol Biol Evol. 2016 May;33(5):1280-92. doi: 10.1093/molbev/msw012. Epub 2016 Jan 27.

PMID:
26823446
49.

AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway.

Hrstka R, Bouchalova P, Michalova E, Matoulkova E, Muller P, Coates PJ, Vojtesek B.

Mol Oncol. 2016 May;10(5):652-62. doi: 10.1016/j.molonc.2015.12.003. Epub 2015 Dec 17.

50.

[Bioinformatics and Next -generation Sequencing].

Krejčí A, Müller P, Vojtěšek B.

Klin Onkol. 2015;28 Suppl 2:2S91-6. Review. Czech.

PMID:
26374164

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